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171 articles for “neurodegeneration Beta-amyloid peptide”
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A Study to Assess the Effectiveness of an Informational Booklet on Knowledge Regarding First Aid for Snake Bite Among People in Selected Rural Community Area of Kanpur Dehat, U.P.
Abstract: Snake bite is a common and frequently devastating environmental and occupational health problem, particularly in rural areas of tropical developing countries. Despite its significant contribution to morbidity and mortality, snake bite remains a neglected public health issue. Snake venoms contain a variety of proteins and peptide toxins with specific actions on different tissue receptors, making snake bite management clinically challenging. Immediate and appropriate first aid plays a crucial role in …
Published in International Journal of Community Health Nursing And Practices · Vol. 4, Issue 1, 2026 · pp. 34–56 Read article
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Nanotechnology-Based Cosmeceuticals for Anti-Aging and Skin Regeneration
Abstract: Nanotechnology has transformed the cosmetic industry of the cosmeceuticals by allowing the production of sophisticated delivery systems that improve the stability, penetration, bioavailability, and therapeutic efficacy of active ingredients in cosmetics. The present review identifies the value of nanotechnology-based cosmeceuticals in anti-aging and skin regeneration, with special focus on the recent developments in nanocarrier technologies and their use in dermatology. Many nanocarriers have exhibited great potentials in enhancing delivery of …
Published in Recent Trends in Cosmetics · Vol. 3, Issue 2, 2026 · pp. 33–45 Read article
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Prospects and Growth Opportunities of Female-Owned Rural Farm Businesses in Plateau State, Nigeria
Abstract: The potential and growth chances of female-owned rural agricultural companies in Nigeria's Plateau State were investigated in this study. The objectives were to assess the prospects and opportunities available to female-owned rural farm businesses and to determine their effect on business growth and development across the state. The study covered female farm business owners engaged in crop production, livestock farming, mixed farming, and agro- processing across all 17 Local Government …
Published in Journal of Energy, Environment & Carbon Credits · Vol. 16, Issue 2, 2026 Read article
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Strategies for the Development and Optimization of Orally Disintegrating Tablets (ODTs) to Improve Bioavailability and Patient Compliance
Abstract: Background: Pharmaceutical scientists have developed Orally Disintegrating Tablets (ODTs) to advance patient drug acceptance and biological system availability through simplified medi-cation delivery especially for children and senior citizens and people who cannot swallow pills regularly. The oral disintegrating tablets dissolve in the mouth within thirty seconds or less (USP 701) while needing no additional liquid thus making them suitable for both emergency treatments. Objective: The research examines ODT development strategies …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 · pp. 50–64 Read article
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Integrative Therapeutics for Antimicrobial Resistance and Autoimmune Disease: Evidence and Pathways
Abstract: Background: Antimicrobial resistance (AMR) is accelerating globally, while autoimmune diseases and adverse drug reactions (ADRs) continue to rise. Ayurveda offers immunomodulatory, antimicrobial, and detoxification‑oriented interventions that may complement biomedical strategies. Objective: To propose a hypothesis‑driven integrative model combining Ayurvedic phytotherapy, panchakarma detoxification, and personalized dosha‑based care with evidence‑based medical management to mitigate AMR emergence, modulate autoimmunity, and reduce ADR incidence. Methods: A synthesis of mechanistic literature on Ayurvedic herbs with …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 2, 2026 · pp. 25–30 Read article
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Mathematical Modeling of Concentration Flux in Thermosensitive Biopolymer-assisted Drug Delivery
Abstract: A mathematical model of drug concentration flux across thermosensitive biopolymer with degradable cross-link was developed to predict the effect of the physical configuration and chemical composition of thermosensitive biopolymer on the kinetics of MK2 inhibitor peptide drug release. The overall goal of this research was to efficiently model the 3D drug release kinetics of a controlled drug from a double-shell spherical nanoparticle. The newly developed model would be used to …
Published in Journal of Thermal Engineering and Applications · Vol. 9, Issue 3, 2022 · pp. 9–15 Read article
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Natural Radioactivity in Fresh Water System
Abstract: Measurement of natural radioactivity in drinking water has been performed for the assessment of the doses and the risks resulting from consuming water. Ingestion is a major pathway for internal exposure; hence, the measurement of radioactivity in drinking water is relevant. The dose contribution is primarily due to the presence of naturally occurring radionuclides of the uranium and thorium series. It is observed that the most natural radioactivity present in …
Published in Journal of Energy, Environment & Carbon Credits · Vol. 2, Issue 1-3, 2012 · pp. 27–36 Read article
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Cancer Treatment by Radionuclide Therapy
Abstract: Recently, pretargeted nuclear imaging and radiotherapy have gained tremendous attention for diagnosis and treatment of cancer with nanomedicines. Radionuclide therapy (RNT) is one of the rapidly growing fields of nuclear medicine which works on the mechanism of delivery of cytotoxic levels of radiation to the disease sites, sparing the normal cells. RNT targets diseases at the cellular level rather than on a topographic anatomical level when compared to conventional external …
Published in Journal of Nuclear Engineering & Technology · Vol. 8, Issue 2, 2018 · pp. 4–7 Read article
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Formulating Pure Natural Polyherbal Hair Dye Preparation for Improved Coloring and Superior Protection Attributes as Compared to Marketed Products
Abstract: AbstractThe commercial synthetic hair dyes include permanent coloring agents like amino compounds (meta-aminophenol, 4-amino-2-hydroxytoluene, etc.), aromatic diamine, polycompounds (para-phenylenediamine), hydric phenols, etc. that precipitates several adverse effects like erythema, skin irritation, skin cancer, loss or damage of hair, etc. In the traditional systems of medicines like Unani, Ayurveda, Homeopathy, and Siddha, the recommended hair dyes are wholly based on plant materials (extracts) and metal oxides (iron oxide, titanium dioxide, etc.). …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 7, Issue 1, 2020 Read article
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Computational Software Assisted Multiple Therapeutic Targets Oriented Screening of Some Natural Alkaloid Compounds
Abstract: The current efforts endeavor towards the computational exploration of some interestingpharmacological potentials of some natural alkaloids by using the Schrodinger Maestro 9.1software. The excellence in therapeutics was screened against five most imperative targets:Cyclin-Dependent Kinase-5 (anti-cancer), Cycloxygenase-2 (anti-inflammatory), Proteinkinase C (anti-cancer), Dipeptidyl peptidase (anti-diabetic), and Angiotensin-1-ConvertingEnzyme (anti-hypertensive). The alkaloids which were previously reported to possessantibiotic activities against Bacillus subtilis, Staphylococcus aureus, and Mycobacteriumsmegmatis and anti-photo-oxidative, have now perceived to be multi-dimensional …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 2, 2019 · pp. 5–9 Read article
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An Introduction to Proteome Bioinformatics
Abstract: For basic and translational research, high-throughput approaches are essential. Recent improvements in proteomics techniques, for example, have allowed biomedical researchers to characterise the proteome of a variety of creatures. Proteome bioinformatics approaches and technologies have greatly aided this extraordinary progress. The study and use of informatics in the realm of proteomics is known as proteome bioinformatics. This chapter presents an overview of the computational strategies, methodologies, and techniques for bioinformatics …
Published in Research and Reviews : Journal of Computational Biology · Vol. 10, Issue 3, 2021 · pp. 7–9 Read article
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A Review on Sarcopenic Obesity: A Rising Epidemic
Abstract: Age-related changes in body composition in geriatrics coupled with increased prevalence of obesity because of immobility and reduced activity gives rise to excess weight and reduced muscle mass or strength; the condition is recently defined as Sarcopenic obesity (SO).The prevalence of sarcopenia and Sarcopenic Obesity increases with age. Muscle and fat mass are strongly interconnected pathogenetically. A better understanding of the mechanisms which lead from loss of muscle mass to …
Published in Research and Reviews: A Journal of Health Professions · Vol. 5, Issue 3, 2015 · pp. 1–5 Read article
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Mucosal Vaccines in Fish: Novel Advances in Technology and Delivery: A Review
Abstract: Vaccines rely on the acquired immune system and prime an animal to a particular antigen so that on subsequent encounter; it is recognized and quickly destroyed. The vast majority of pathogens enter the body via the mucosal surfaces of the gastrointestinal, respiratory, and urogenital tracts, where they initiate mucosal infections that lead to systemic infections. There is strong evidence that an optimum mucosal immune response can prevent systemic infection and …
Published in Research and Reviews : A Journal of Immunology · Vol. 9, Issue 1, 2019 · pp. 14–26 Read article
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Characterization of a Broadly Specific LPS-Neutralizing Single Domain Antibody
Abstract: Gram negative endotoxaemia or sepsis remains a lethal challenge to humans and animals, globally. Single domain antibodies (dAbs) have emerged as therapeutic biologics for challenging antigens such as lipopolysachharide (LPS). The present study characterized a broadly specific LPS-neutralising dAb produced from phage display library from LPS-immunized Indian desert camel, for its sequence validation with mass spectrometry. Also, the dAb clone 26 was subjected to co-crystallisation with LPS, extracted from E. …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 1, 2017 · pp. 1–7 Read article
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Vaccine Candidates and Animal Models for Kala-Azar
Abstract: Kala-azar or Visceral Leishmaniasis (VL) is a serious human disease in tropical regions and rapidly emerging as an opportunistic infection in HIV patients. The available treatment against VL is associated with toxicity and drug resistance. Even though the development of vaccines against VL is received limited attention. The only successful immunization strategy in humans has been leishmanization, which is based on the development of durable immunity after recovery from infection …
Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 1, 2015 · pp. 29–35 Read article
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Cryptosporidium parvum Mediated Diarrhea in Immunocompromised Patients
Abstract: Cryptosporidium parvum is one of the important diarrheal agents, especially in malnourished children and immunocompromised patients. Of the many species, Cryptosporidium parvum and Cryptosporidium hominis are the two major species that cause water borne outbreaks. The geographic difference in the distribution of parasite has been attributed to sources and its mode of transmission. The parasite is able to survive in the environment for long time and is resistant to many …
Published in Research and Reviews : A Journal of Immunology · Vol. 6, Issue 3, 2016 · pp. 5–9 Read article
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Progress from the Traditional Vaccines to Novel Rational Vaccine Designs
Abstract: Vaccines are among the most valuable assets for saving human and animal lives. The vaccines discovered and designed on the Pasteurian principles laid the foundations of the traditional vaccine regime during the late-19th century. Some traditional vaccine designs proved remarkably successful, while others had safety or efficacy problems, and still others failed- particularly those against diseases caused by non-cultivable, hyper-variable or opportunist pathogens, or those requiring cellular immunity. The problems …
Published in Research and Reviews : A Journal of Immunology · Vol. 6, Issue 3, 2016 · pp. 17–31 Read article
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A short review on scenario of Type 1 diabetes in Australia
Abstract: Type 1 diabetes (T1D) is caused by an autoimmune attack on pancreatic beta cells that leads to insulin deficiency. The incidence of T1D in Australia has doubled over the past 20 years. T1D treatment focuses on physiological insulin replacement, aiming for near-normal blood glucose levels. Morbidity and mortality result in hypoglycemia in T1D. Better results can be achieved by following some of the new technologies which includes insulin pumps, continuous …
Published in Research and Reviews : A Journal of Immunology · Vol. 9, Issue 2, 2019 · pp. 1–5 Read article
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A Review on Current Scenario and Update on Vaccine for Covid-19
Abstract: Background: COVID-19 pandemic is caused by SARS-CoV-2 . The SARS-CoV-2 is a beta coronavirus belonging to the family of Coronaviridae. The outbreak of novel coronavirus had a major impact on health care professionals like physicians, pharmacist, microbiologist etc. Current scenario of detection of SARS-CoV-2(COVID-19) is made through a nasopharyngeal swab based on RT-PCR technique. Some novel recent studies suggest the evidence of the possible role of fluid which is present …
Published in Research and Reviews : A Journal of Immunology · Vol. 10, Issue 3, 2020 · pp. 1–7 Read article
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β-cell Deficit Due to Increased Apoptosis Islet Cell Plasticity in Humans Type 2 Diabetes
Abstract: Beta cells (β cells) in the pancreatic islets produces insulin and the number of functional insulin-producing β-cell contributes to the pathophysiology of type 2 diabetes . Type 2 diabetes is a chronic disease characterized by the deficiency in β-cells and increase in the levels of sugar in blood. β cells promote inflammation in obesity and type 2 diabetes. The low β-cell accumulation in Type 2 diabetes paves way to diabetes …
Published in Research and Reviews : A Journal of Immunology · Vol. 11, Issue 1, 2021 · pp. 1–7 Read article