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538 articles for “efficacy”
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Antibiotic Resistance: Molecular Mechanisms of Resistance
Abstract: Antibiotics are called as ‘Wonder Drugs’, the miracles of modern sciences. They help combat bacteria and prevent their growth. But due to unmonitored and uncontrolled consumption of these antibiotics, there is an emergence of antibiotic resistance. This has led to a series of downfall in the therapeutic potency and efficacy of many drugs. More and more bacteria are becoming Multi-Drug Resistant (MDR); such highly resistant strains of certain bacteria are …
Published in Research and Reviews: A Journal of Microbiology and Virology Read article
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Numerical Study and Comparison of Passive Mixing in Helical Micromixers
Abstract: A passive mixing inside three micromixers has been studied with water as the mixing fluid. Since the mixing at the micro-level is governed by species diffusion hence it is a time-consuming process that requires an extended length of micromixer for the required amount of mixing. The present study tackles this problem by introducing two helical micromixers, a Three-dimensional helical micromixer (TDHM), and TDHM having four inlets (TDHM-FO). These micromixers need …
Published in Journal of Polymer & Composites Read article
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Exploring The Multitarget Pharmacological Mechanism of Diabex for T2dm by Combining Network Pharmacology and Molecular Docking Techniques
Abstract: Objective: Hyperglycemia brought on by an absolute or relative absence of insulin synthesis or action characterises a set of illnesses known as diabetes mellitus. Chronic hyperglycemia in diabetes mellitus has been linked to organ damage, heart, and blood vessels. The persistent metabolic condition Diabetes is a severe global issue with negative social, health, and economic effects. It is a type of metabolism disorder that interferes with food digestion in the …
Published in International Journal of Bioinformatics and Computational Biology Read article
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Youthful Students’ Perception of The Nursing Profession: A Preliminary Single-group Research
Abstract: Aim: This study had four objectives: (1) examine how adolescents perceive nursing before and after organized teaching programs; (2) examine how adolescents perceive nursing after structured teaching programs; (3) compare pre-test and post-test results to assess the efficacy of a structured teaching program; (4) relate the mean improvement in nursing image to particular demographic factors. Background: This study assists in identifying potential areas for improvement or any potential interventions to …
Published in International Journal of Community Health Nursing And Practices · Vol. 1, Issue 2, 2023 Read article
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Molecular Docking and Pharmacokinetic Profiling of the Phytocompounds of Jatropha curcas as Antagonist for Salmonella typhi
Abstract: Background: Typhoid is an infection caused by the Gram-negative bacterium, Salmonella enterica serovar typhi. The study assessed the potential use of Jatropha curcas as a typhoid fever therapy alternative to traditional medications. The ability to uncover novel drug indications for currently available medications using in silico methods has increased thanks to the wealth of pharmacological and biological knowledge that is available. Objective: In this study, we assessed the potential inhibitory …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 · pp. 67–81 Read article
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Evaluation of Inhibition Effect of Nanohybrid Curcumin (Cur-ZnO) and Cur-free Against Some Types of Bacteria
Abstract: This study aimed to prepare an efficient nanohybrid food preservative by loading curcumin on zinc oxide. The prepared compound was characterized using microscopy and spectral methods. Fourier transform infrared spectrum of the nanohybrid curcumin showed a shift in the frequencies of some chemical groups towards high and low frequencies. X-ray diffraction (XRS) spectrum also revealed the emergence of new diffraction planes in the nanohybrid compound, Compared with the carrier spectrum …
Published in Journal of Polymer & Composites · Vol. 11, Issue 2, 2023 · pp. 68–79 Read article
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Development and Evaluation of a Novel Polyaniline/Polyvinyl Alcohol/Silver Nanocomposite for Antibacterial Applications: Synthesis and Characterization
Abstract: A novel nanocomposite made up of polyaniline, polyvinyl alcohol, and silver (PAL/PVA/Ag) was synthesized using the reduction of chemical technique in this study. Aniline was polymerized in situ with ammonium persulfate to create polyaniline (PAL), while Ag+ ions were employed to make an nanoparticle of Ag colloidal solution. The combination of Ag nanoparticles with the PAL/PVA composite resulted in the development of a new nanocomposite. Scanning electron microscopy (SEM) and …
Published in Journal of Polymer & Composites · Vol. 11, Issue 3, 2023 · pp. 39–47 Read article
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A Novel Approach to Fingerprint Authentication Using Histogram Oriented Gradients for Feature Extraction and Machine Learning Convolution Neural Network for Classification
Abstract: With applied biometrics, it is possible to identify a person by examining a feature vector of attributes derived from their physical and behaviour characteristics. In biometrics, fingerprints have become one of the most famous and well known techniques of identification and authentication. In light of technological advancements and safety, fingerprint recognition has been successfully used in a variety of Civil, Defence, and Commercial applications for more than a decade. The …
Published in International Journal of Wireless Security and Networks · Vol. 1, Issue 2, 2023 · pp. 1–12 Read article
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Application of Grey Wolf Optimizer (GWO) strategy for Malware Analysis
Abstract: The ever-evolving landscape of cybersecurity necessitates continuous advancements in malware analysis techniques. This study explores the deployment of the Grey Wolf Optimizer (GWO) algorithm as a novel bio-inspired optimization mechanism to address the challenges posed by modern malware threats. The primary objective is to enhance various facets of malware analysis, including feature selection, parameter optimization, and the overall efficacy of malware detection models. The study begins by introducing the GWO …
Published in International Journal of Wireless Security and Networks · Vol. 1, Issue 2, 2023 · pp. 43–53 Read article
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Numerical Analysis and Comparison of Various Cross Sections of Heat Pipes in Heat Exchanger
Abstract: The present work describes about numerical analysis of heat pipe with different cross sections such as L-shape, U-shape, wave and spring configurations. The effect of various configurations of heat pipe plate exchanger are examined by considering temperatures, velocities, pressure depressions. The numerical values of Reynolds number, Nusselt number, heat transfer were calculated at different velocities. The outcome of numerical analysis found that it influences fluid flow and pressure depression. Hence, …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 74–81 Read article
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Assessment of the Impact of a Structured Educational Program on PCOS Knowledge Among Adolescent Girls in a Chosen Area of Tarn Taran District, Punjab
Abstract: Polycystic ovary syndrome (PCOS) is a health condition characterized by elevated levels of androgen hormones, irregular menstrual patterns, and the existence of small cysts on one or both ovaries. The disorder can be morphological or biochemical. Prevention of PCOS includes lifestyle modifications that are to manage weight, exercise, and dietary changes. Aim and Objectives: The main goal of this study was to assess the efficacy of a structured educational program …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 36–41 Read article
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Isolation and Evaluation of Aspergillus Niger : A Fungi Implicated in Infectious Diseases and its application as potential Biofertilizer
Abstract: In the quest to improve the agronomic effectiveness of Rock Phosphate (RP), a widely available and cost-effective phosphate fertilizer, this study aimed to overcome its limited solubility by isolating fungal strains capable of solubilizing rock phosphate. Soil samples were collected from Garhmukteshwar, Hapur, for the isolation process. Among several isolates, three strains exhibited the highest rock phosphate solubilization within a seven-day timeframe, coinciding with a significant decrease in soil pH. …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 2, 2024 · pp. 29–34 Read article
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Designing a Novel Insider Threat Model for Enhanced Cybersecurity
Abstract: Designing a novel insider threat model is a critical imperative in the realm of cybersecurity. As organizations face an ever-expanding threat landscape, insider threats, whether deliberate or inadvertent, present a formidable challenge to the safeguarding of sensitive data and critical assets. This abstract encapsulates the significance, challenges, and innovations inherent in crafting an effective insider threat model for enhanced cybersecurity. The necessity for novel insider threat models arises from the …
Published in International Journal of Information Security Engineering · Vol. 1, Issue 2, 2023 · pp. 24–27 Read article
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A Quasi-experimental Research Project Designed to Evaluate the Impact of a Structured Educational Program on the Awareness of Cervical Cancer Prevention Among Adolescent Girls Attending Specific Schools in Moga, Punjab
Abstract: A quasi-experimental research study aims to evaluate the efficacy of a structured educational program in enhancing the understanding of cervical cancer prevention among adolescent girls in specific schools located in Moga, Punjab. The knowledge score of adolescent girls in experimental group regarding prevention of cervical cancer was average (20%) and below average (80%), before imparting the structured teaching programme knowledge of adolescent girls were good (70%) and average (30%). The …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 1–9 Read article
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Evaluating Epidemiological and Physical Risk Factors in the Development of Chemotherapy-induced Peripheral Neuropathy (CIPN): An In-depth Systematic Review and Meta-analysis
Abstract: Background of study: Chemotherapy-induced peripheral neuropathy (CIPN) encompasses a range of adverse effects caused by various cytotoxic medications and stands as a primary source of pain among individuals who have survived cancer. In instances of pronounced and sudden CIPN, it might become necessary to diminish chemotherapy dosages or discontinue their application. Currently, no efficacious strategy exists for proactively preventing CIPN, managing established chronic CIPN is constrained, and the risk factors …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 10–21 Read article
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Advancements in Energy-Efficient Electrical Motor Design: A Comprehensive Review
Abstract: The rapid growth in energy demand poses a fundamental challenge for the whole power industry in fulfilling the increased demand. An exhaustive energy audit recommends substituting energy-efficient gadgets with conventional ones, which function with low efficiency and waste a significant amount of electricity. Electric motors are quite common in contemporary life, providing energy to a wide range of devices, including both domestic and industrial machinery. Nevertheless, they bear the responsibility …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 1, Issue 1, 2023 · pp. 29–35 Read article
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Tools, Modern Drugs, and Latest Investigations for the Diagnosis and Treatment of Heart Failure: A Systematic Review of the General Causes
Abstract: Heart failure (HF) diagnosis and treatment present formidable challenges, given the absence of a definitive single test. This systematic literature review aims to comprehensively analyze the current landscape of diagnostic tools, modern drugs, and latest investigative approaches in HF management. Recognizing the complexity of HF etiology, this systematic review emphasizes the importance of advanced diagnostic methods, such as genetic testing and artificial intelligence applications. The systematic review was conducted to …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 1–10 Read article
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Experimental Investigation on Heat Transfer Characteristics of Thermal Barrier Coating on Aero Engine Components
Abstract: The gas turbine blades play a crucial role in harnessing energy from the high-temperature and highpressure gas generated by the combustor. To withstand this challenging environment, turbine blades often employ super-alloys and incorporate new manufacturing technologies such as Direct Solidification (DS) and Single Crystal (SC). Additionally, the development of advanced ceramic Thermal Barrier Coating (TBC) is imperative to achieve higher operating temperatures (>1200°C). Therefore, the primary focus of this study …
Published in Journal of Polymer & Composites · Vol. 11, Issue 13, 2023 · pp. 50–58 Read article
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Exploring the properties and extraction of neem leaves
Abstract: Neem (Azadirachta indica) is a versatile medicinal plant, for its diverse therapeutic properties. This abstract provides a comprehensive overview of recent research focusing on phytochemical analysis, biochemical characterization, and antimicrobial susceptibility testing of Neem extracts. Utilizing the different from of chemical used in it, phytochemical analysis identified a plethora of secondary metabolites within Neem, including alkaloids, flavonoids, terpenoids, steroids, saponin, tannins, quinone, and phenolic compounds, indicative of its complex chemical …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 2, 2024 · pp. 32–39 Read article
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The Use of Autologous Platelet-Rich Plasma in Treating Web Space Scar Contractures in Pediatric Burn Patients
Abstract: Burn injuries are prevalent among children, with scald injuries emerging as the predominant type among those under the age of five, constituting more than 65% of cases. Despite receiving appropriate initial treatment and compressive therapy, deep burns often result in contractures, with web space and hand contractures being the most frequent and functionally limiting.To address these challenges in burn management, Autologous Platelet Rich Plasma (APRP) has emerged as a significant …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 1, 2024 · pp. 1–5 Read article