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166 articles for “drug response”
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Towards Intelligent Healthcare: Artificial Intelligence’s Impact on Healthcare
Abstract: Artificial Intelligence (AI) stands as a transformative force within healthcare, offering multifaceted support to various processes and medical professionals. This comprehensive study investigates the extensive array of AI applications and its potential to reshape the healthcare landscape. Specifically, it examines the utilization of deep-learning methodologies in harnessing vast medical datasets to enhance healthcare provision. Expanding beyond theoretical discussions, this study scrutinizes AI's role in breast cancer, seizure, and tumor detection, …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 11, Issue 2, 2024 · pp. 77–83 Read article
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Dermatophytoses: Taxonomy, Pathogenesis, Diagnosis, Resistance, and Management.
Abstract: Dermatophytes, belonging to the family Arthrodermataceae, are keratinophilic fungi responsible for superficial mycoses. Dermatophytoses affect the skin, hair, and nails globally. Over the last few years, dermatophytic infections have seen a sharp rise in India, with the main causative agent being antifungal-resistant Trichophyton mentagrophytes genotype VIII. This review provides a detailed overview of dermatophytoses, including taxonomy, pathogenesis, epidemiology, diagnosis, and treatment. Dermatophytes belong to the kingdom Fungi, family Arthrodermataceae, with …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 28–37 Read article
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Biopolymer Hydrogels: Patent Insights and Emerging Technological Trends
Abstract: Hydrogel biopolymers have become a valuable resource for next-generation functional materials due to their inherent properties, including compatibility with biological systems, environmental degradability, and minimal toxicity. Intelligent gels that respond to changes in temperature, pH, or ionic strength have various applications across industries like pharmaceuticals, biomedical engineering, and the food sector. This review systematically compiles findings from patent disclosures and non-patent literature to highlight recent trends in biopolymer-based hydrogel research, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 916–924 Read article
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Prevalence and Distribution of Staphylococcus Aureus in Clinical Samples Across Age Groups
Abstract: The bacteria that cause everything from ordinary skin infections to serious illnesses is called Staphylococcus aureus. It is now known that Staphylococcus aureus may develop resistance to a variety of drugs. Staphylococcus aureus has been displaying an unusual kind of resistance to antibiotics, especially to those based on β-lactum. As a result, Methicillin Resistant Staphylococcus Aureus (MRSA) is the new name for the resistant strain of Staphylococcus aureus. The prevalence …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 15–19 Read article
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Revolutionizing Artificial Organs: Next-Generation Membrane Technologies for Precision Medicine and Global Health
Abstract: Membrane technology has emerged as a cornerstone in the advancement of artificial organ systems, offering critical functionalities in selective molecular filtration, tissue scaffolding, and controlled therapeutic delivery. Recent innovations have propelled the field beyond traditional polymeric membranes to include nanostructured, biomimetic, and stimuli-responsive materials, significantly enhancing biocompatibility, selectivity, and durability. The integration of smart technologies, such as AI-driven membrane design, bioelectronic sensors, and personalized fabrication via 3D printing, is ushering …
Published in International Journal of Membranes · Vol. 2, Issue 2, 2025 · pp. 29–39 Read article
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The Impact of Artificial Intelligence on the Sales and Marketing of Pharmaceutical Products
Abstract: The rapid development of computing and technology has permeated all branches of science, with artificial intelligence (AI) emerging as a pivotal field in computer science. AI has significantly influenced disciplines ranging from basic engineering to pharmaceuticals. In healthcare and medicinal chemistry, AI applications have become indispensable. Traditional drug discovery approaches are gradually being overtaken by computer-aided drug design. In recent years, artificial intelligence (AI) and machine learning (ML) have become …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 1, 2025 · pp. 10–18 Read article
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Biomarkers in Cancer Research: Discovery and Future Directions
Abstract: Biomarkers have transformed the study of cancer, providing critical information regarding prognosis and therapy response and promoting earlier diagnosis. This paper discusses the different parts of cancer biomarkers, starting with their description, classification, and major types, which are the groundwork for understanding their clinical role. The discussion on the development and validation process of biomarkers is then undertaken, focusing on state-of-the-art techniques and the importance of ensuring accuracy and reproducibility. …
Published in Trends in Drug Delivery · Vol. 12, Issue 1, 2025 · pp. 22–26 Read article
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The Mycobiome Frontier – Pre & Post 2020 Status: Integrating Fungal Bioactive Compounds, Probiotics, and Antimicrobial Peptides in Modern Therapeutics and Biotechnology.
Abstract: The fungal kingdom represents an indispensable resource in modern therapeutics and biotechnology, offering a diverse array of bioactive compounds, probiotics, and antimicrobial peptides (AMPs). Functional fungal polysaccharides (FFPs), such as beta-glucans, chitin, and mannans, are centrally involved in modulating the human gut microbiota, providing novel therapeutic avenues for chronic conditions including diabetes, neurodegenerative disorders, and cancer. These compounds act as prebiotics, nourishing beneficial bacteria and enhancing metabolic parameters such as …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 1–11 Read article
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Consumer Awareness and Adoption Barriers of E-Pharmacy Services in Delhi/NCR: A Mixed-Methods Investigation
Abstract: Background: The rapid digitization of India's pharmaceutical market has positioned e-pharmacies as a transformative force; yet, consumer adoption remains significantly low despite growing awareness. Objectives: This study investigates consumer awareness levels, purchasing behaviors, trust perceptions, and adoption barriers regarding e-pharmacy services among urban Indian consumers. Methods: A sequential explanatory mixed-methods design was employed. Quantitative data were gathered via a structured questionnaire administered to 65 respondents in Delhi. Qualitative insights were …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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Antimicrobial Resistance: - A Growing Serious Threat for Global Public Health
Abstract: Antibiotics, among the most significant discoveries of the 20th century, have prevented infectious diseases from claiming millions of lives. However, their widespread use and misuse have created strong selection pressure, enabling microbes to develop antimicrobial resistance (AMR) to many drugs. Over time, AMR has spread primarily through human-to-human contact, both within healthcare settings and in the community. It is driven by a complex interplay of healthcare and agricultural factors, including …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 Read article
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Artificial Intelligence in Microbiological Research: Methods, Applications and Implications
Abstract: Artificial Intelligence (AI) is revolutionising microbiological research by enabling the rapid analysis of complex biological data and improving the accuracy, efficiency, and reliability of scientific investigations. Recent advances in machine learning, deep learning, and bioinformatics have transformed AI into a powerful tool for studying microorganisms, their genetic composition, evolutionary patterns, and interactions with hosts and the environment. AI-driven computational models can process large and complex datasets far more efficiently than …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 2, 2026 Read article
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Visualization of genomic sequence in BRCA1 and BRCA2
Abstract: Heredity is the main reason of breast cancer in women and mutation or genetic variations also another reason for the spread of breast cancer. Heredity and genetic variations are responsible 5%-10%, 30%-50% respectively. There are 90% chances of developing neoplasm by the mutations. The effect of BRCA1 and BRCA2 may leads to the variations in DNA therefore it should be in limited amounts so that there will be minimum changes …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 49–55 Read article
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Photochemically Assisted LC–MS Method Development and Validation for Stability-Indicating Determination of Glasdegib in Rat Plasma
Abstract: A simple, precise, and cost-effective LC–MS method was successfully developed for the determination of Glasdegib in rat plasma. The method optimization was carried out by systematically varying key chromatographic parameters, including flow rate, injection volume, analyte concentration, and mobile phase composition, to achieve optimal sensitivity and resolution. A C18 Hypersil BDS column (150 mm × 4.6 mm, 3.5 µm particle size) was used for chromatographic separation, offering effective peak shape …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 1, 2026 · pp. 11–20 Read article
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Understanding the Impact: Adult BCG Vaccination in the Fight Against Tuberculosis
Abstract: Tuberculosis (TB) remains a big global health challenge, with significant mortality rates, especially in developing nations. India holds most TB cases throughout the globe. As HIV rates, multidrug-resistant tuberculosis (MDR-TB), and extensively drug-resistant tuberculosis (XDR-TB) continue to increase, the situation is deteriorating. These all come in the way of the End TB epidemic campaign by the World Health Organization (WHO) by 2030. Immunology and vaccinology represent critical fronts in TB …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 · pp. 1–6 Read article
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The Renaissance and Resilience of CB1 Reverse Agonists: From Central Liabilities to Peripheral Promise
Abstract: Building upon these foundational insights, current research has increasingly focused on refining the pharmacological profile of CB1 reverse agonists to maximize therapeutic benefit while minimizing central adverse effects. The adverse neuropsychiatric outcomes associated with first-generation agents such as Rimonabant including anxiety, depression, and suicidal ideation highlighted the critical role of central CB1 receptors in mood regulation. Consequently, drug development strategies have shifted toward peripherally restricted CB1 reverse agonists that exhibit …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 30–35 Read article
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UV Method of Development and Validation of Olaparib
Abstract: An analytical method must be developed and validated in the discovery, development, and production of pharmaceuticals to ensure the identification, purity, potency, and performance of drug commodities. Quality control laboratories use official test protocols that emerge from the processes. A simple ultraviolet spectrophotometric approach was designed and validated using various characteristics, including linearity. Precision, reproducibility, accuracy, robustness, ruggedness, limit of detection, and limit of quantification are among the measuring criteria. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 20–27 Read article
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Mass Spectrometry–Based Phosphoproteomic Markers to Predict Kinase Inhibitor Response in Solid Tumors
Abstract: Mass spectrometry-based phosphoproteomics has emerged as a powerful tool for predicting kinase inhibitor responses in solid tumors, offering direct functional insights into signaling pathways that surpass traditional genomic profiling by capturing dynamic kinase activities and adaptive resistance mechanisms. Technological breakthroughs, including data- independent acquisition (DIA), trapped ion mobility spectrometry (timsTOF), and efficient enrichment methods like TiO2 or IMAC, now enable comprehensive profiling of over 40,000 phosphorylation sites from limited clinical …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 2, 2026 Read article
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In Silico Molecular Docking of Indigofera tinctoria Phytocompounds to Target EGFR/ERK and FGFR/FGF Pathway Proteins Involved in Prostate Cancer
Abstract: Objective: Prostate cancer being the second major cause of cancer-related deaths in males, affects the small walnut-shaped gland below the bladder called the prostate gland. The epidermal growth factor protein (EGFR), cascade protein (ERK), and fibroblast growth factor proteins (FGFR and FGF) are involved in the different signaling pathways that lead to the formation of different products, that are responsible for the progression of cancer and thus can be considered …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 34–56 Read article
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Phosphorescence of Carbon Nanodots – The Phenomena and the Applications
Abstract: Photoluminescence has emerged as a fundamental phenomenon in modern biomedical science, enabling advanced diagnostic, therapeutic, and theranostic applications through light–matter interactions at the nanoscale. The ability of photoluminescent materials to absorb electromagnetic radiation and emit light at distinct wavelengths has been widely exploited in bioimaging, biosensing, drug delivery tracking, and photodynamic therapy. Among various photoluminescent nanomaterials, carbon nanodots have attracted significant attention due to their strong emission intensity, tunable fluorescence, …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 1, 2026 · pp. 01–05 Read article
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Sequence analysis, DNA Methylation and Molecular therapy of Oral cancer caused by Human Papilloma Virus
Abstract: DNA methylations with oral cancer are been associated with high-risk Human Papillomavirus (HPV) and Epstein-Barr Virus (EBV) onco-proteins interactions may cooperate to increase disease severity. The work focused on human papillomavirus strain 16, a high-risk, sexually transmitted responsible for 95% of all cervical cancers and a large portion of oropharyngeal cancers. The prediction of genes from has shown seven genes from HPV16 strain. Based on gene identification studies, Human papilloma …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 2, 2026 · pp. 1–9 Read article