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318 articles for “absorption”
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UV Method of Development and Validation of Olaparib
Abstract: An analytical method must be developed and validated in the discovery, development, and production of pharmaceuticals to ensure the identification, purity, potency, and performance of drug commodities. Quality control laboratories use official test protocols that emerge from the processes. A simple ultraviolet spectrophotometric approach was designed and validated using various characteristics, including linearity. Precision, reproducibility, accuracy, robustness, ruggedness, limit of detection, and limit of quantification are among the measuring criteria. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 20–27 Read article
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Exploring Biomedical Innovations in the Formulation and Assessment of Medicated Hard Candy Lozenges Containing Metoclopramide Hydrochloride
Abstract: The objective of this study was to formulate and evaluate metoclopramide hydrochloride medicated lozenges for antiemetic action through buccal absorption by incorporating a polymer. All formulations were developed and assessed for in-vitro drug release, physical appearance, weight variation, thickness, hardness, moisture content, mouth-dissolving time, and drug content. The prepared lozenges exhibited uniformity in weight and thickness. The hardness of all formulations ranged between 7.3–15.50 kg/cm², falling within standard limits. The …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 50–62 Read article
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A Study of Environmental Pollution in Some Areas of the City of Najaf for Some Heavy Metals
Abstract: Pollution is one of the most important problems that people face at the present time, and the problem of soil pollution is the most serious, due to its relationship to human health and other organisms. Soil sample collection areas in the city of Najaf were chosen based on several factors, including traffic, industrial and urban activities, and population density. Soil samples were taken at a depth level ranging between 0-15 …
Published in Research & Reviews : Journal of Ecology · Vol. 13, Issue 2, 2024 · pp. 14–23 Read article
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To Study Properties of Concrete by Using Manganese Ore Aggregate
Abstract: Aggregate is one of the major ingredients of the concrete and the maximum part of strength of the concrete is governed by the aggregate. And thus, partial or total replacement of it can change the physical as well as the chemical properties of the concrete. Nowadays researchers are quite interested in obtaining the more durable and more resisting concrete to the diverse climatic conditions. In this research, aggregate is proportionately …
Published in Journal of Construction Engineering, Technology & Management · Vol. 14, Issue 2, 2024 · pp. 38–45 Read article
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Li-Fi based Underwater Audio and Data Transmission System
Abstract: Visible Light Communication, or Li-Fi (Light Fidelity), is a wireless optical networking technique used for communication (VLC). Due to its lack of RF communication's drawbacks, such as water absorption and scattering, Li-Fi has the potential to completely transform underwater communication. This project suggests utilizing two Arduinos, a solar panel, a speaker, a display, an amplifier, a laser, a battery, and other components to create a Li-Fi based underwater audio and …
Published in Recent Trends in Fluid Mechanics · Vol. 11, Issue 2, 2024 · pp. 23–29 Read article
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Anticancer Activity of Calotropis procera by Molecular Docking Analysis
Abstract: Cyclin-dependent kinase 2 (CDK2) is a protein synthesized by Calotropis procera. It is known to be responsible for causing cancer in the human body. Studies have presented the significance of the phytochemicals to inhibit the CDK2 protein. Adsorption, distribution, metabolism, and excretion (Swiss ADME) and PubChem were the pharmacological tools which were used to check molecular weight, which should be less than 500D, acceptors less than 10, and donors less …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 01–07 Read article
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Oral Thin Films of Ondanetron Hcl: Formulation and Performance Evaluation
Abstract: This study had the goal to formulate oral polymeric thin film that would dissolve and disintegrate instantly, while also having high mechanical features. These are the most advanced forms of solid dosage forms. Solvent casting was the technique employed to create oral thin films. These are additionally referred to as buccal films/strip, mouth dissolving films, oral thin films, as well as oral strips of paper. These films are suitable for …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 3, 2024 · pp. 1–6 Read article
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The Evaluation of the Light Parameters and Pleural Fluid Cholesterol to Determine the Differences Between Exudative and Transudative Pleural Discharge
Abstract: Background: Pleural effusion occurs when an imbalance between pleural fluid production and absorption leads to the accumulation of excess fluid in the pleural cavity. Pleural effusions are commonly classified into two types: transudative or exudative, depending on the underlying mechanism of fluid formation. While transudates typically result from systemic factors like heart failure or liver cirrhosis, exudates are usually caused by local factors such as infection, malignancy, or inflammation. Differentiating …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 30–35 Read article
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Herbal Dusting Powders: A Comprehensive Review of Benefits, Applications, and Market Trends
Abstract: Herbal dusting powders are gaining popularity as a natural alternative to conventional talcum powders, offering benefits such as moisture absorption, soothing skin irritations, and preventing friction. This review article explores the multifaceted aspects of herbal dusting powders, focusing on their composition, therapeutic benefits, sustainability, regulatory considerations, and consumer trends. The article delves into the wide array of herbal ingredients used in these powders, including neem, chamomile, lavender, and sandalwood, each …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 3, 2024 · pp. 21–27 Read article
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Selected Heavy Metals Levels (Cu, Cr, Cd, Pb, Fe) in Gwadabawa Lake, Sokoto State, Nigeria
Abstract: The main aim of this work was to determine the concentrations of some heavy metals, specifically Cu, Cd, Pb, Cr and Fe in Gwadabawa lake, Gwadabawa Local Government, Sokoto State using standard methods (atomic absorption spectroscopy) and materials of analytical grade. The results were analyzed. The range of Fe concentration was 0.01 ± 0.001 to 1.37 ± 0.3(ppm), and range of Cu concentration determined was 0.00 to 0.02±0.008(ppm). The range …
Published in International Journal of Minerals · Vol. 1, Issue 1, 2024 · pp. 8–15 Read article
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Groundwater Quality Assessment for Drinking and Irrigation Purposes in Tadimarri Mandal, Sri Sathya Sai District, Andhra Pradesh Using Water Quality Index and Geospatial Techniques
Abstract: Groundwater is the primary source of potable water and supports agriculture worldwide. Assessing its quality is vital to determine its suitability for various purposes, especially as a safe drinking water source. This study focuses on evaluating the quality of groundwater used for drinking and irrigation in Tadimarri Mandal, Anantapur district, Andhra Pradesh, India. During the pre-monsoon season, 30 groundwater samples were collected from boreholes and analyzed for physicochemical parameters. The …
Published in Journal of Remote Sensing & GIS · Vol. 15, Issue 3, 2024 · pp. 1–19 Read article
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Flaxseed and Diabetes Management: A Comprehensive Review of Recent Studies and Potential Mechanisms
Abstract: Diabetes mellitus, a condition characterized by chronic hyperglycemia, has become a significant global health challenge, leading to substantial morbidity and mortality rates. Dietary techniques are crucial for the effective control of diabetes, including both pharmaceutical and non-pharmacological therapies. Flaxseed (Linum usitatissimum) is one of the functional foods that has attracted a lot of interest because of its abundance of bioactive components, including lignans, dietary fiber, and alpha-linolenic acid (ALA). The …
Published in International Journal of Nutritions · Vol. 2, Issue 1, 2025 · pp. 24–32 Read article
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Geochemometric Assessment of Primordial Radionuclides and Trace Elements in Coastal Sediments: Environmental and Radiological Implications for South India
Abstract: This study focuses on environmental radioactivity and trace element contamination in coastal sediments along the southern region of the Indian subcontinent, from the Palar River to Pulicat Lake. Utilizing gamma-ray spectroscopy with a NaI (Tl) detector, along with atomic absorption spectroscopy, the research examines the spatial distribution and activity concentrations of primordial radionuclides—namely, 238U, 232Th, and 40K—as well as trace elements such as Ni, Pb, Mn, Zn, Cu, Co, Fe, …
Published in International Journal of Minerals · Vol. 1, Issue 1, 2024 · pp. 33–37 Read article
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Development of Sodium Alginate Beads of Telmisartan Using Emulsion Gelation Method: Formulation and In-Vitro Characterization
Abstract: Introduction: The antihypertensive medication Telmisartan (TEL) is a member of BCS class II, which is distinguished by limited oral rate and extent and water solubility. By localizing the medication release in the stomach, gastro-retentive floating bead devices may be able to address the issues related to partial absorption and the low solubility of TEL. The preparation of TEL floating alginate beads was the aim of this investigation. The current work …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 3, 2024 · pp. 13–21 Read article
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Structural, Electrical and Optical Properties of RGO-Incorporated PVA Nanocomposites for UV Shielding Applications
Abstract: Polymer matrix-based nanocomposites reinforced with appropriate nanoparticles have the potential to exhibit improved electrical, optical and mechanical properties, as well as improved UV-shielding capabilities. These materials are currently being utilised for various commercial applications, such as window shields and automotive components. We prepared reduced graphene oxide (rGO)-incorporated polyvinyl alcohol (PVA) polymer nanocomposites employing a solution casting method. XRD and SEM results confirmed that the rGO nanosheets were dispersed well in …
Published in Journal of Polymer & Composites · Vol. 12, Issue 6, 2024 · pp. 119–137 Read article
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Analysis of Physical Properties of Polyethylene Terephthalate Coated Aggregates used in Bituminous Concrete Mixes
Abstract: The main cause of climate change that the world has been facing for several years is burning of plastic waste in open air. To contribute to solution of this problem, an investigation was carried out with utilization of plastic waste in bituminous mixtures used in flexible pavement.With varied amounts of Polyethylene Terephthalate (0%, 6%, 6.5%, 7%, 7.5%, and 8%) of asphalt content, variousdesirable properties of aggregates required for bituminous mix …
Published in Journal of Polymer & Composites · Vol. 12, Issue 6, 2024 · pp. 206–213 Read article
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A Review on: Oral Thin Films: A New Approach to Effective and Easy Drug Delivery
Abstract: Oral Thin Film (OTF) is an advance drug delivery system in which drug is incorporated into dissolvable strip and place in oral cavity for rapid absorption. OTF is useful for patient such as pediatric and geriatric who have difficulty swallowing pills. It provides rapid action, precise dosage and improved bioavailability. OTFs consist of fast-dissolving films, extended-release films, and mucoadhesive films for various therapeutic applications. The manufacturing processes of OTFs such …
Published in Trends in Drug Delivery · Vol. 11, Issue 3, 2024 · pp. 22–41 Read article
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Targeting Vasopressin 2 Receptor (V2R) in Renal Cystogenesis by Exploring the Nephroprotective Potential of “Terminalia arjuna”
Abstract: Objectives: Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disorder, leading to the formation of multiple cysts in the kidneys. It is a major cause of end-stage renal disease (ESRD), which often requires dialysis or a kidney transplant for survival. This research focuses on identifying potential bioactive compounds derived from natural sources that show promise for drug development targeting the V2R gene. Methods: The naturally occurred …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 2, 2024 · pp. 14–24 Read article
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Exploring the Potential of Allium sativum Phytocompounds as B-Cell Leukemia 2 Inhibitors in Acute Lymphoblastic Leukemia: Molecular Docking Study
Abstract: Objective: Acute lymphoblastic leukemia (ALL) is a lymphoid progenitor cell malignancy that could be treated with plant-based drugs, thus alleviating the off-target effects caused by conventional chemotherapy. Since ancient days, Allium sativum has been an integral part of traditional medicine and an excellent antimicrobial, antioxidant, and antiproliferative agent. Hence, this study aims to assess the anti-leukemic potential of A. sativum phytoconstituents as the B-cell leukemia 2 protein (Bcl-2) natural inhibitor …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 2, 2024 · pp. 53–80 Read article
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Casein - A Unique Milk Protein
Abstract: Milk is a nutrient-rich food that contains proteins, fats, lactose, vitamins, minerals, enzymes, and other organic compounds. Essential for young mammals, milk proteins provide amino acids, nitrogen, and minerals necessary for muscle and tissue development. In human nutrition, milk is valued for its digestibility and as a source of calcium and phosphorus, crucial for infant growth. Milk proteins are classified into two primary types: caseins, which make up 75–80% of …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 13, Issue 3, 2024 · pp. 27–34 Read article