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1680 articles for “BCS Class II/IV drugs”
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Histoplasma capsulatum (Dimorphic Fungus) in India: Biological Features, Virulence Mechanisms, and Clinical Implications of Histoplasmosis.
Abstract: Histoplasmosis is a systemic mycosis caused by the thermally dimorphic fungus Histoplasma capsulatum. Infection is acquired primarily by inhalation of infectious microconidia and may range from asymptomatic infection to severe disseminated disease. Although histoplasmosis has classically been associated with the river valleys of the Americas, it is being increasingly recognized in Asia, including India, where it frequently mimics tuberculosis, leishmaniasis, lymphoma, and leprosy, resulting in delayed diagnosis and treatment. Cutaneous …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 38–48 Read article
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Marine Fungi – An Expandable Source for Production of Novel Bioactive Metabolites: A Comprehensive Review
Abstract: The marine environment, representing the largest and most extreme biome on Earth, serves as an unparalleled reservoir of biodiversity. Within this vast ecosystem, marine fungi have emerged as a prolific source of structurally diverse and pharmacologically active secondary metabolites. Dwelling in habitats characterized by extreme high salinity, high hydrostatic pressure, and low temperatures, these microorganisms have evolved unique biochemical and metabolic pathways to synthesize novel compounds, including pyrrole-imidazole alkaloids, cyclic …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 30–37 Read article
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Fungi in the Global Bioeconomy: Harnessing the R Potential Across Agriculture, Medicine, Industry, and Environmental Sustainability
Abstract: One of the most diverse and functionally versatile groups of living organisms, fungi has played a significant role in maintaining ecological balance, human well-being, agricultural production, and industrial processes. Despite their vast potential, the use of fungi systems in solving some of the most serious challenges facing the world today, such as climate change, food security, and AMR, is still in its infancy. New developments in genomics, biotechnology, and systems …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 20–27 Read article
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Dermatophytoses: Taxonomy, Pathogenesis, Diagnosis, Resistance, and Management.
Abstract: Dermatophytes, belonging to the family Arthrodermataceae, are keratinophilic fungi responsible for superficial mycoses. Dermatophytoses affect the skin, hair, and nails globally. Over the last few years, dermatophytic infections have seen a sharp rise in India, with the main causative agent being antifungal-resistant Trichophyton mentagrophytes genotype VIII. This review provides a detailed overview of dermatophytoses, including taxonomy, pathogenesis, epidemiology, diagnosis, and treatment. Dermatophytes belong to the kingdom Fungi, family Arthrodermataceae, with …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 28–37 Read article
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Bridging the Gap Between Product Development and Entrepreneurship in Engineering Curriculum: A Framework-Based Approach Aligned with NEP 2020
Abstract: Despite advancements in technical education, Indian engineering graduates frequently enter the workforce lacking critical competencies in product development (PD) and entrepreneurship. This imbalance has drawn scrutiny from industry and policymakers alike, with national directives such as the National Education Policy (NEP 2020) emphasizing a shift toward “experiential, holistic, integrated and inquiry-driven” learning models. Similarly, the All-India Council for Technical Education (AICTE) has embedded innovation labs, internship mandates and entrepreneurship courses …
Published in International Journal of Education Sciences · Vol. 3, Issue 1, 2026 · pp. 87–100 Read article
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Transforming Hospital Environments: The Role of Sound Detection
Abstract: Hospitals are sanctuaries of healing, yet they are often paradoxically exposed to a pervasive, often underestimated threat: excessive noise. While internal hospital sounds pose their own challenges, the impact of external sounds – traffic, construction, sirens, and urban clamor – can profoundly compromise patient safety, recovery, and overall well-being. This article explores the critical role of advanced sound detection systems in mitigating this external acoustic intrusion, leveraging technology to create …
Published in International Journal of Electrical and Communication Engineering Technology · Vol. 4, Issue 1, 2026 · pp. 28–40 Read article
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LQR-Based Optimal Control of Inverted Pendulum System with State Estimation and Stability Analysis
Abstract: The inverted pendulum on a cart is a canonical benchmark problem in control systems engineering, capturing the essential challenges of stabilizing an inherently unstable, underactuated, and nonlinear plant. Classical Proportional-Integral-Derivative (PID) controllers, while widely employed in industrial practice, exhibit fundamental performance limitations when applied to such systems, primarily due to their inability to account for multivariable coupling, process noise, and the absence of a systematic optimization framework. This paper presents …
Published in International Journal of Advanced Control and System Engineering · Vol. 4, Issue 1, 2026 · pp. 31–43 Read article
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Damage Evolution and Delamination Resistance in Polymer Matrix Functionally Graded Laminates
Abstract: Functionally graded laminates (FGLs) in polymer-matrix systems represent a promising pathway to enhance damage tolerance and delay delamination in advanced structural composites. In this study, we explore the mechanisms of damage initiation, propagation, and delamination resistance in polymer matrix functionally graded laminates (PM-FGLs) through a combined experimental–computational approach. Laminates with linear, exponential, and bio-inspired gradation profiles were fabricated using vacuum-assisted resin transfer molding (VARTM) and additive manufacturing techniques. Comprehensive mechanical …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 321–337 Read article
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A Review on Evolution of Aircraft Fuselage Materials: From Wood to Composites & Functionally Graded Materials
Abstract: This article presents a comprehensive overview of the evolution of materials for construction of aircraft fuselages, with a focus on the expanding use of polymer composites and functionally graded materials (FGMs) in modern aerostructures. The baseline fuselage design is thought to be from wood, to be followed by metallic systems such as aluminum, titanium, and nickel alloys. All systems improved manufacturability, strength, and longevity, but there was a substantial revolution …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 447–455 Read article
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Face Recognition Attendance System Using Local Binary Pattern Histogram Algorithm
Abstract: Maintaining accurate and tamper-proof attendance records in educational and corporate environments has long been a challenge due to the limitations of manual and biometric systems. This study introduces the development and deployment of a contactless, automated attendance system that utilizes facial recognition through the local binary pattern histogram (LBPH) algorithm. The primary goal is to offer a secure and efficient substitute for conventional attendance methods by harnessing the power of …
Published in Journal of Image Processing & Pattern Recognition Progress · Vol. 13, Issue 1, 2026 · pp. 29–34 Read article
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Integrating Advanced Technologies for the Scientific Revalidation of Ayurvedic Principles
Abstract: Background: Ayurveda, a 5,000-year-old holistic healthcare system, emphasizes the dynamic balance of body, mind, and spirit. Recent advancements in science and technology have accelerated its integration into global healthcare systems. Objective: This paper explores the contribution of modern tools and methodologies to the scientific validation and enhancement of Ayurvedic principles across education, clinical practice, and research. Methods: A comprehensive literature review was conducted using databases like PubMed, Google Scholar, and …
Published in Research and Reviews: A Journal of Medicine · Vol. 16, Issue 1, 2026 · pp. 1–6 Read article
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CNN-Based Diagnosis of Skin Cancer from Dermoscopic Images
Abstract: Skin cancer has become one of the diseases widely spread over the globe, with melanoma becoming a severe threat to one’s health. Detection of such diseases at the initial stage saves an individual from drastic damage. Using a Convolutional Neural Network (CNN) for detecting skin cancer through image classification as benign or malignant provides significant support to dermatological practice and reduces dependence solely on subjective visual examination. Dermatologists often face …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 1, 2026 · pp. 37–42 Read article
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Parametric Study of Laser Drilling Process Using Multi Variable Regression Analysis
Abstract: The laser drilling process is an advanced manufacturing technique extensively employed for intricate and high-value components in aerospace, automotive, and electronics industries. Laser drilling technology offers opportunities to meet the contemporary demands of industries using a broad spectrum of engineering materials. However, this process encounters several engineering challenges such as thermal damage, dimensional inaccuracies, and the formation of a recast layer in the drilled components. This study focuses on examining …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1000–1015 Read article
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Immunological Mechanisms Underlying Autoimmune Disorders: Recent Advances and Therapeutic Implications
Abstract: A diverse range of illnesses known as autoimmune disorders are typified by dysregulated immune responses against self-antigens, which result in tissue damage and persistent inflammation. Understanding the genetic, epigenetic, and environmental variables that contribute to autoimmune pathogenesis has advanced significantly during the last ten years. Current disease models have been transformed by new understandings of immunological tolerance mechanisms such as the functions of regulatory T cells, cytokine networks, and the …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 1, 2026 · pp. 21–25 Read article
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IoT-Based Structural Health Monitoring and Damage Detection in Fiber Reinforced Polymer Composite Structures
Abstract: Applications of fiber-reinforced polymer (FRP) composite in the aerospace, civil infrastructure and renewable energy systems are increasing due to the fact that the composite possesses high ratio of strength to weight and can resist corrosion. However, processes of internal damages such as the cracking of the matrix, delamination and fiber fracture, are likely to take place without being visible on the surface and therefore a periodic check of the structure …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1076–1100 Read article
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Nitrosamine Accumulation, Processing Variables, and Indigenous Plant Inhibitors in Nigerian Traditionally Processed Meats
Abstract: N-nitrosamines are classified as probable or possible human carcinogens by the International Agency for Research on Cancer. Carcinogenic N-nitrosamines — principally N-nitrosodimethylamine (NDMA) and N-nitrosodiethylamine (NDEA) — are formed in abundance during the preparation of widely consumed Nigerian traditional processed meats including suya, kilishi, and balangu. This original investigation combined a six geopolitical zone of Nigerian market survey with laboratory-controlled model system experiments, effects of processing parameters on N-Nitrosamine formation …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 17, Issue 1, 2026 · pp. 61–72 Read article
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IOT and algorithmic intelligent motor health monitoring as well as maintenance prediction
Abstract: Manufacturing, transportation, and energy systems rely largely on industrial electric motors, and their untimely failure can result in expensive downtime, safety hazards, and decreased operational efficiency. The majority of traditional motor maintenance procedures rely on reactive methods or routine inspections, which frequently miss early-stage problems and lead to needless maintenance or unexpected breakdowns. This project offers an Intelligent Motor Health Monitoring and Predictive Maintenance System that combines Internet of Things …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 4, Issue 1, 2026 · pp. 28–37 Read article
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Nutrient–Xenobiotic Crosstalk in Dairy Cattle: Implications for Metabolism, Immunity, Health, and Productivity in Resilient Dairy Development
Abstract: Dairy cattle are routinely exposed to a wide range of xenobiotics, including mycotoxins, heavy metals, pesticides, residues from veterinary drugs, and plant secondary metabolites, through feed, water, and environmental sources. These xenobiotics, being foreign to biological systems, can interfere with the absorption, metabolism, and utilization of essential nutrients, while also compromising immune function, organ health, and overall physiological performance. Chronic or subclinical exposure can reduce feed efficiency, disrupt energy and …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 16, Issue 1, 2026 · pp. 37–46 Read article
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An Adaptive and Privacy-Aware Federated Learning Framework for Efficient and Secure Model Training Across Heterogeneous Datasets
Abstract: The problem of efficiency and privacy regarding heterogeneous data in modern distributed machine learning systems is a vital point that should be taken into account. The absence of IID data distribution, client heterogeneity, and privacy invasion during the aggregation model are the bane of conventional federated learning (FL) approaches to learning like FedAvg and FedProx. The paper proposes that the adaptive and privacy-aware FL framework (AFL-P) can be used to …
Published in Journal of Mobile Computing, Communications & Mobile Networks · Vol. 13, Issue 1, 2026 · pp. 16–25 Read article
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Sustainable Green Solvents: Ionic Liquid-Based Hydrogels
Abstract: Green solvents have been widely used in a wide range of applications, such as catalysis, separation sciences, energy storage and pharmaceutical applications. The main ingredient in the collection of the environmentally benign reagents is ionic liquids (ILs). Ionic liquid-based hydrogels are being used in the biological sciences and medicinal chemistry fields because of their excellent biocompatibility and biosafety features. The versatility of ionic liquids is great, as they can be …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1263–1274 Read article