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1133 articles for “integrative review”
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Unlocking Potential: Capecitabine’s Evolution as an Anticancer Wonder Drug
Abstract: Capecitabine, a precursor to 5-fluorouracil (5-FU), is Anticancer Drug in treating solid tumors like colorectal, breast, and gastric cancers. Its mechanism involves converting to 5-FU mainly within tumor cells, reducing toxicity while maximizing effectiveness. Besides being effective alone, it is also valuable in combination therapies, showcasing its versatility in cancer treatment. This review explores the transformative journey of capecitabine as a pivotal anticancer drug. Beginning with an introduction to its …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 17–24 Read article
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A Critical Review on Permanent Catenary Mooring Health Monitoring and Evaluation Technologies
Abstract: Recent times have seen the proliferation of Oil and Activities in increasing deeper waters. In such context, fixed structures are no longer a viable option. Floating structures applied for deepwater developments comprise of several major floater concepts that are either moored in position or employ dynamic positioning. For permanently anchored Floating Production Systems, the vessel and mooring systems are expected to withstand up to 10,000 years return period storms. Permanent …
Published in Journal of Offshore Structure and Technology · Vol. 1, Issue 3, 2014 · pp. 1–12 Read article
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Planar Light wave Circuits: Reviews and Applications
Abstract: PLCs are waveguide devices that integrate fiber-matched optical waveguides on a silicon or glass substrate to provide an efficient means of interaction for guided-wave optical signals. PLCs are used in optical wavelength-division multiplexing, time-division multiplexing systems, and subscriber networks. This study examines recent advancements in PLC technologies such as arrayed-waveguide grating multiplexers, optical add-drop multiplexers, and hybrid optoelectronics integration technologies, as well as their future possibilities. Silicon photonics has lately …
Published in Journal of Microelectronics and Solid State Devices · Vol. 9, Issue 1, 2022 · pp. 26–28 Read article
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Review article on Quality Control in Clinical Trials
Abstract: Quality control (QC) is a critical component in the conduct of clinical trials, ensuring the accuracy, reliability, and credibility of data collected throughout the study. It encompasses a systematic set of procedures designed to monitor trial conduct and data integrity, thus safeguarding the rights, safety, and well-being of participants. This review explores the principles, implementation, and evolving practices of quality control in clinical trials, highlighting its importance across all phases …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 01–07 Read article
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Intelligent Paradigms in Subsea Connectivity: A Comprehensive Review of Artificial Intelligence in Underwater Communications
Abstract: Underwater wireless communication (UWC) plays a critical role in ocean exploration, environmental monitoring, offshore energy operations, disaster management, and naval defense. However, the underwater environment presents significant communication challenges, including severe signal attenuation, multipath propagation, Doppler effects, limited bandwidth, high latency, and energy constraints. Recent advancements in Artificial Intelligence (AI) and Machine Learning (ML) have emerged as promising solutions to address these limitations and enhance the efficiency, reliability, and adaptability …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 13, Issue 3, 2025 Read article
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Current Trends in Optimization of Parameters of Electric Discharge Machining Process: A Review
Abstract: Wire-cut electrical discharge machining (EDM) is an emerging machining process for machining hard-to-machine materials and intricate shapes which are impossible to make with conventional machining process. The optimum selection of input parameters for the wire electrical discharge machining (WEDM) process is based mainly on the technology used and experience of the operator. This paper reviews the effect of most significant input process parameters of WEDM such as pulse on, pulse …
Published in Trends in Mechanical Engineering & Technology · Vol. 6, Issue 2, 2016 · pp. 25–33 Read article
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Polymer Chemistry-Guided Development of Biomimetic Composite Scaffolds
Abstract: Polymer chemistry plays a fundamental role in advancing biomaterials for anatomical tissue engineering, particularly in the design of composite scaffolds that replicate the intrinsic characteristics of native tissues. The regeneration of damaged tissues, especially within anatomically complex structures such as bone, cartilage, and skin, necessitates biomaterials that closely emulate the hierarchical architecture and biological functions of native extracellular matrices (ECMs). The capacity to replicate both mechanical and biochemical cues of …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 7–13 Read article
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FLUTTERCHAT: A Real-time Firebase Chat Application with AI-based Chatbot
Abstract: Recently, the development and deployment of chatbots have gathered significant attention from both developers and researchers. Chatbots represent AI-driven conversational systems capable of understanding and responding to human language using advanced techniques like Natural Language Processing (NLP) and Neural Networks (NN). A cutting-edge real-time chat application has been crafted using Flutter and OpenAI, seamlessly integrating an AI-powered chatbot with an innovative image generator to enrich user interaction and engagement. The …
Published in Journal of Mobile Computing, Communications & Mobile Networks · Vol. 12, Issue 1, 2025 · pp. 42–51 Read article
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Circadian Regulation of Lipid Peroxidation in the Brain: Linking Ferroptosis to Neurodegenerative Vulnerability
Abstract: The human brain operates through highly coordinated physiological and biochemical processes that regulate cognition, behavior, and neural adaptability. Central to these processes are mechanisms governing brain function, neurophysiology, and neuroplasticity, which are increasingly recognized to be influenced by circadian rhythms. Recent advances in cognitive neuroscience, neuroimaging, and behavioral neuroscience have revealed that disruptions in circadian regulation can significantly impact oxidative balance within the brain, particularly through enhanced lipid peroxidation. Lipid …
Published in International Journal of Brain Sciences · Vol. 3, Issue 2, 2026 · pp. 1–14 Read article
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A Comprehensive Review on FinFet Technology : Advantages, Challenges and Applications
Abstract: New devices and enhanced layers have been developed, specially the FinFET (Fin Field-Effect Transistor) which is considerably superior to the planar transistor because of its ability to meet the new demands of systems for high-performance, low-power, and dimensions reduction. Some of the recent developments in FinFETs mentioned in this review include a reduction of leakage currents by 50% and an enhancement of the speed by 30%; thus, FinFETs remain fundamental …
Published in Journal of Semiconductor Devices and Circuits · Vol. 11, Issue 4, 2024 Read article
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A Brief Review on Perovskite Materials: Synthesis, Properties, and Applications
Abstract: Perovskite materials have emerged as a transformative class of compounds, capturing widespread interest due to their remarkable properties and diverse applications across various fields, including optoelectronics, catalysis, energy storage, and environmental technologies. The synthesis techniques, classification, and unique properties of perovskite materials are thoroughly examined in this paper, which highlights the materials' potential to completely transform a number of sectors. One of the standout features of perovskites is their highly …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 1, 2025 · pp. 42–49 Read article
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A Review on Digital Twin Technology in Robotics
Abstract: Digital Twin (DT) technology has emerged as a transformative concept in robotics and automation, enabling virtual representation of physical systems, real-time monitoring, and performance optimization. This review explores the foundations of Digital Twin, its integration in robotic systems, key enabling technologies, applications, current challenges, and future research directions. The paper concludes by highlighting how Digital Twin transforms design, control, prediction, and human-robot collaboration.Digital Twin technology is transforming the field of …
Published in International Journal of Manufacturing and Production Engineering · Vol. 4, Issue 1, 2026 · pp. 10–15 Read article
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Radiopaque Polymer Composites for Improved Visualization of Interventional Devices
Abstract: Radiopaque polymer composites are increasingly important for improving the visualization of interventional medical devices under X-ray and fluoroscopic imaging while maintaining the flexibility, mechanical performance, and processability required for minimally invasive applications. This narrative review summarizes recent developments in radiopaque polymer composites, with emphasis on radiopaque filler selection, polymer–filler interactions, processing strategies, structure–property relationships, biocompatibility, and device applications. A focused literature search was conducted using PubMed, Scopus, Web of Science, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Microbial Safety of Dairy Products
Abstract: Microbial safety is paramount in the dairy industry to ensure the production of high-quality and safe dairy products for consumers. This review article explores the microbial pathogens associated with dairy products, including bacterial and fungal species such as Listeria monocytogenes, Salmonella spp., Escherichia coli, Staphylococcus aureus, mycotoxigenic molds, and yeast species. We delve into the primary routes of contamination, emphasizing sources such as raw milk, processing equipment, and cross-contamination during …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 12, Issue 3, 2023 · pp. 7–11 Read article
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Dynamic Modeling and Simulation of Multi-Body Mechanical Systems: A Comprehensive Review of Methods, Tools, and Applications
Abstract: The dynamic modeling and simulation of multi-body mechanical systems (MBS) form a cornerstone in modern mechanical engineering, enabling in-depth analysis of the kinematic and kinetic behaviors of interconnected rigid and flexible components. MBS are foundational to a range of critical applications, from automotive suspensions and aerospace mechanisms to robotics and biomechanical structures. As system complexity and performance requirements increase, accurate and scalable modeling techniques are essential for both design validation …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 3, Issue 1, 2025 · pp. 35–42 Read article
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Full-Stack Web Development for Intelligent User Interfaces: Integration of MERN and Rails
Abstract: In the modern era of web development, by providing users with flexible, responsive, and interactive designs, Intelligent User Interfaces (IUIs) greatly improve the user experience. A hybrid method for constructing intelligent, scalable, as well as efficient online apps is discussed in this review work, which focuses on the integration of Ruby on Rails with the MERN stack (MongoDB, React.js, Express.js, Node.js). The MERN stack excels in dynamic frontend development, while …
Published in Journal of Web Engineering & Technology · Vol. 12, Issue 3, 2025 · pp. 15–25 Read article
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Herbal Frontiers: The Role of Alternative Remedies in Combating Typhoid Fevers
Abstract: Typhoid fever, caused by Salmonella typhi, remains a major health challenge, particularly in developing regions where sanitation and healthcare resources are limited. With an estimated global incidence of 17 million cases annually, the disease poses a significant public health burden. The growing resistance to conventional antibiotics, such as fluoroquinolones and third-generation cephalosporins, exacerbates treatment challenges. This has spurred interest in alternative remedies, including herbal and homeopathic treatments.Herbal medicine offers a …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 Read article
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Weaning Age Shaping Puberty in Heifer: Insights from Nutritional, Physiological, Hormonal and Environmental Perspectives
Abstract: The onset of puberty in dairy heifers is a critical determinant of their reproductive performance and overall productivity. This study reviews the influence of weaning age on the timing and quality of puberty, synthesizing insights from nutritional, physiological, hormonal, and environmental perspectives. Early or late weaning can significantly impact heifer development, influencing body weight, fat deposition, and metabolic health. Nutrition plays a vital role in shaping growth rates and reproductive …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 14, Issue 1, 2025 · pp. 19–31 Read article
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Biomedical Coatings: Surface Engineering for Enhanced Biocompatibility and Performance
Abstract: Biomedical coatings have become essential in modern healthcare, significantly improving the performance, durability, and biocompatibility of medical implants and devices. These coatings serve multiple functions, including reducing infection risks, enhancing osseointegration, promoting tissue integration, and enabling localized drug delivery. Advances in surface engineering have led to the development of innovative coatings with superior properties such as antimicrobial resistance, bioactivity, and controlled biodegradation. Various materials are employed in biomedical coatings, including …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 1, 2025 · pp. 8–15 Read article
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Risk Factors Associated with Subclinical Mastitis in Dairy Cows: Implications for Microbial Dynamics, Environmental Influences, and Management Factors
Abstract: Subclinical mastitis is a prevalent yet often overlooked condition in dairy cows, leading to reduced milk yield and quality. This study examines the microbial dynamics, environmental influences, and management factors contributing to subclinical mastitis in dairy herds. Microbial agents, including bacteria such as Staphylococcus aureus, Escherichia coli, and Streptococcus uberis, are key contributors, with their ability to persist and form biofilms complicating detection and treatment. Environmental factors, including bedding quality, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 2, 2025 · pp. 45–61 Read article