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314 articles for “Toxicity”
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A Review of Different Polymer and Plasticizers
Abstract: Plasticizer and polymer are essential components in the pharmaceutical industry, especially when creating both cutting-edge and conventional drug delivery systems. The differences between synthetic, semi-synthetic, and all-natural polymers are examined in this review to highlight their diverse qualities and uses. When designing drug delivery systems to target areas, the choice of polymer is crucial. Because of their repeatability and adaptability, synthetic polymers are widely used in the creation of precision …
Published in International Journal of Membranes · Vol. 1, Issue 1, 2024 · pp. 1–7 Read article
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Precision Medicine for Neurofibromatosis Type 1: Progress and Prospects in Drug Discovery
Abstract: Objective: The development of neurofibromas, café-au-lait spots, and other neurological problems are the hallmarks of neurofibromatosis type 1 (NF1), a hereditary disorder. The dearth of efficacious pharmaceutical therapies underscores the need for novel therapeutic approaches, even in the face of clinical variability. Through very accurate prediction of the binding affinity of possible therapeutic drugs with the target protein, the computational technique known as “molecular docking” has become a potent tool …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 01–15 Read article
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Molecular Docking Studies for the Identification of Mycobacterial Adenosine Triphosphate (ATP) Synthase Inhibitors Using Active Phytocompounds from Plants Curcuma longa, Curcuma zedoaria and Galipea officinalis
Abstract: Objective: Tuberculosis (TB), known in human history for several decades, remains the second leading infectious disease after COVID-19. Still, the occurrence of TB increases due to the bacterium’s greater survival nature. They can survive in extreme conditions by being in long latency and adapting to the host. This study seeks to identify potential inhibitors from Curcuma longa, Curcuma zeodaria, and Galipea officinalis based on ancient folklore and compare them against …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 16–26 Read article
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Hydroponics Culture Regulated Metabolic Variations in Plants of Medicinal Value
Abstract: The current review chiefly brings to light the importance of alternative cultivation strategies for medicinal plants about the effective enhancement of the bioactive substances. The fast-paced society is favoring the need for its cost-effective cultivation and studying the effects thereafter. The mis-steps while collecting the plant from the wild lead to identification issues, genetic and phenotypic variations, variable bioactive substances/secondary metabolites, and toxic compounds. So, cultivation happening in controlled environments, …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 2, 2024 · pp. 14–20 Read article
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Design of Coal Mine Safety and Monitoring System Using Sensors and IOT
Abstract: The paper proposes the application of a network of wireless sensors deployed within coal mining safety systems to oversee the operational environment and bolster safety protocols within coal mines. The system consists of master controllers and slave controllers, where the slave controllers detect dangers and send alerts to the master controller through Wi-Fi, enabling quick action to be taken. The system is powered by the NodeMCU microcontroller and includes various …
Published in Journal of Thermal Engineering and Applications · Vol. 11, Issue 1, 2024 · pp. 1–7 Read article
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In Silico Investigation of 2,3-Dihydrobenzofuran from Centella asiatica: A Possible Pioneer in the Management of Tetanus
Abstract: Objective: Tetanus toxin (TeNT) is a neuroprotein toxin, the most toxic known. They have three functional domains and are structurally similar. They possess an N-terminal catalytic section (light chain), an internal domain for heavy-chain translocation (HN domain), and a C-terminal receptor binding domain for the heavy chain (Hc domain or RBD). Tetanus, an acute nerve-affecting disease, is provoked by a toxin-producing bacterium called Clostridium tetani. This bacterium is environmental, Gram-positive, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 19–30 Read article
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Unlocking Potential: Capecitabine’s Evolution as an Anticancer Wonder Drug
Abstract: Capecitabine, a precursor to 5-fluorouracil (5-FU), is Anticancer Drug in treating solid tumors like colorectal, breast, and gastric cancers. Its mechanism involves converting to 5-FU mainly within tumor cells, reducing toxicity while maximizing effectiveness. Besides being effective alone, it is also valuable in combination therapies, showcasing its versatility in cancer treatment. This review explores the transformative journey of capecitabine as a pivotal anticancer drug. Beginning with an introduction to its …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 17–24 Read article
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Synthesis and Functional Group Analysis of Solution Processed Zinc Oxide Thin Film Grown on Polyethylene Terephthalate
Abstract: Flexible electronics field is growing every day. Existing technology is facing issues like brittleness, toxicity, inadequacy. Fabrication cost increases in processing of such materials. In this work, zinc oxide nanoparticles synthesized by solution processing technique were used to grow 120nm thick thin film (TF) on Polyethylene terephthalate (PET). This method reduces the processing cost and Zinc Oxide (ZnO) is cheaper and abundant in comparison to other semiconductors option. Material was …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 56–66 Read article
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Impact of Marine Pollution Threats and Conservation of Marine Biodiversity
Abstract: Ocean occupies 71% of earth’s surface and is traditionally divided into four large basins including North and South Atlantic, North and South Pacific, Arctic and Indian oceans. In India we have a vast coastal area of 7516.6 km from Kolkata to Gujarat and also many islands including Andaman and Nicobar and Lakshadweep with vast fin and shellfish biodiversity. Human interference and both natural and artificial factors pose the biggest threat …
Published in International Journal of Marine Life · Vol. 1, Issue 1, 2024 · pp. 20–24 Read article
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A Perspective Review on Role of Environmental Pollutants in Developing Neurodegenerative Diseases
Abstract: As human society progresses towards industrialization, an excess number of environmental pollutants are released to our ecosystem, which significantly contribute in causing various health issues primarily associated with neurodegenerative diseases such as cognitive disorder, dementia, anxiety, Alzheimer, Parkinson etc. Because of their high global occurrence, these diseases have attracted attention in recent decades, however, the etiology of these diseases remains unclear. Pollutants are discharged into the environment by natural events …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 2, 2024 · pp. 1–18 Read article
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Recovery of Mycelial Biomass of Agaricus Bisporus, Pleurotus Ostreatus, Ganoderma lucidum, Hieracium Erinaceus: A comparative Study
Abstract: Mushrooms are the spore-bearing fruiting body of fungi which has a significant potential for numerous applications like pharmaceuticals, textile industry, bioremediation, soil management, alternative to toxic packaging materials and environment sustainability. Mushrooms generally belongs to the class Basidiomycota or Ascomycota. They are typically made of hyphae, the tiniest threads which comprises most fungi. Mycelia are tiny thread like structure which help in making vegetative part of fungus. In this study, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 2, 2024 · pp. 12–18 Read article
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Investigations Into the Potential for Anthracene Decomposition of Novel Soil Bacterium, Pseudomonas putida P7
Abstract: Bioremediation of hazardous contaminants holds immense importance for the preservation of a clean and healthy environment. Conversely, the accumulation of toxicants can be mitigated with the assistance of microorganisms capable of breaking down these harmful substances into benign molecules. Anthracene is frequently used as a model molecule for studies on PAH pollution because it is found in many carcinogenic PAHs. Therefore, the hunt for new microorganisms with the ability to …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 2, 2024 · pp. 29–44 Read article
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NanoBioAI: Utilizing Python to Investigate Magnetocaloric Effects in Magnetotactic Bacteria and Optimized Conditions for Thermotherapy
Abstract: The study presented in the research work represents a multidisciplinary approach, integrating biology, nanotechnology, and artificial intelligence. It specifically highlights the use of python computational power to investigate magnetocaloric effect (MCE) in magnetotactic bacteria (MTB), a phenomenon yet to be fully understood, characterized by reversible heating and cooling effects induced by magnetic fields. MTB are unique in that they contain embedded magnetic nanoparticles ranging from 10–100 nm in diameters. These …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 11, Issue 2, 2024 · pp. 122–131 Read article
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Develop And Assess a Multifunctional Herbal Face Pack
Abstract: This study aims to develop and assess a multifunctional herbal face pack that reduces tan lines and brightens skin through the trituration of herbal ingredients. Following preparation, the formulation is assessed using a variety of criteria, including, extrudability, stability, irritant test, physicochemical, and organoleptic factors. Physically, the formulation was found to be good, devoid of skin irritation, and able to retain its consistency even after stability in storage. An herbal …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 2, 2024 · pp. 1–7 Read article
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An experimental investigation of Prosopis Juliflora Biodiesel’s performance and emission characteristics
Abstract: Fossil fuels are currently in crisis due to their higher cost, their increasing use, and their scarcity. In view of the large number of cars on the road and the emission levels caused by combustion ignition engines, fuel substitutes are sought. Diesel is the most expensive fuel on the market, so biodiesel is a good alternative. Aside from its low toxicity, it reduces greenhouse gas emissions, does not emit sulphur, …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 67–75 Read article
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Properties of ZnO Thin Film deposited on Flexible Substrate using RF Sputtering
Abstract: Semiconductor materials demand is increased in recent years, due to new emerging technologies. There is need to find the alternate for silicon in electronics industry, as silicon is brittle in nature and has low efficiency, which makes it unsuitable for transparent and flexible device. Zinc oxide (ZnO) is emerging as popular choice of researchers due to its wide range of properties, abundancy and non-toxicity. This work explores the properties of …
Published in Journal of Polymer & Composites · Vol. 12, Issue 4, 2024 · pp. 50–56 Read article
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Case Study on Snake Bite
Abstract: Snakebites are a major public health concern in India, with the World Health Organization (WHO) estimating approximately 5 million cases annually. Out of these, around 2.7 million involve envenomation, where venom is injected through the snake's bite. These venomous bites pose significant medical emergencies and can lead to severe complications, including permanent physical impairments if not treated promptly. Immediate medical intervention is crucial to mitigating the adverse effects of snakebites. …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 2, 2024 · pp. 21–25 Read article
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Eco-Friendly Elixirs: A Critical Review of Biosurfactants for Sustainable Wastewater Solutions
Abstract: Biosurfactants are the amphiphilic substances which are acquired from the remains of the living microorganisms and have attracted a lot of scientific interests because of their applicability in various fields. This review aims at reviewing current research and development on biosurfactants with special emphasis on their application in wastewater and oil. Biosurfactants being less hazardous to the environment are produced by microorganisms and works as a substitute for chemically produced …
Published in Emerging Trends in Chemical Engineering · Vol. 11, Issue 2, 2024 · pp. 14–33 Read article
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Nucleonic Level Measurement in Fluid Catalytic Cracking Unit, Oil & Gas Refinery
Abstract: The measurement of ‘Level’ is crucial in an Industrial Process, as low levels can cause problems and damage equipment. In contrast, high levels can cause overflow and potentially create safety and environmental problems. When working with the Fluid Catalytic Cracking System Unit (FCCU) in Refineries, there are requirements for various types of level measurement instruments. One of them is the Nucleonic Level Measurement device used in the process involved in …
Published in Emerging Trends in Chemical Engineering · Vol. 11, Issue 3, 2024 · pp. 41–49 Read article
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Development of Herbal Mosquitoes repellent candle
Abstract: Citronella oil and essential oil are commonly used for their insect-repellent properties. They’re important for creating natural insect repellents, candles, and sprays, offering a safer alternative to chemical-based products. Citronella oil is particularly effective against mosquitoes, making it invaluable for outdoor activities and protecting against insect-borne diseases like malaria and Zika virus. Its pleasant scent also adds to its appeal as a natural air freshener. In a mosquito repellent study, …
Published in Recent Trends in Cosmetics · Vol. 1, Issue 2, 2024 · pp. 8–12 Read article