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465 articles for “Toxic effects”
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Comprehensive Insights into Toxicology: Mechanisms, Applications, and Modern Developments
Abstract: Toxicology, the study of the harmful effects of substances on living organisms, has become increasingly vital in today's world due to industrial growth, agricultural advancements, and heightened exposure to environmental and chemical toxins. This article examines the foundations of toxicology, exploring its definitions, core principles, and mechanisms of action. It also delves into specialized branches such as forensic, environmental, and medical toxicology, highlighting the differences between toxicants, toxins, and poisons, …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 1, 2025 · pp. 31–37 Read article
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Molecular Mechanism of Fluoride Induced Oxidative Stress and Its Possible Reversal by Chelation Therapy
Abstract: Fluorine (Fl) a member of the halogen family is the most electronegative and reactive of all the elements of the Periodic table. Chronic and acute exposures of fluoride leads to cardiovascular disease (hypertension and atherosclerosis), neurological disorders, gastrointestinal disturbances, liver disease, renal disease, reproductive effects, other health disorders and also affects the antioxidant system in the body. Furthermore, reactive oxygen species (ROS)-mediated oxidative damage is a common malady in fluoride …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 2, 2013 · pp. 7–34 Read article
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Toxicity of Alpha-Cypermethrin on Fish
Abstract: Alpha-cypermethrin is a type II synthetic pyrethroid. Synthetic pyrethroids are used extensively for the control of insect pest and public health purpose. A fresh water fish was exposed to lethal concentration and sub lethal concentration of alpha-cypermethrin, respectively to observe the enzyme activity in functionally two different tissues—gills and liver. The present article focusses on non-target organism in fresh water environment and critically evaluates the toxicity of these pyrethroids in …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 10, Issue 2, 2021 · pp. 33–38 Read article
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From Trace to Truth: Integrating Forensic Science, Analytical Chemistry, Medical Evidence and Artificial Intelligence in Modern Criminal Investigation
Abstract: Modern criminal investigations are inherently interdisciplinary, integrating medical research, forensic science, analytical chemistry, and artificial intelligence (AI) to transform hazy traces into reliable, legally recognised evidence. This study examines the ways in which different domains collaborate across the whole investigation process, ranging from judicial review, laboratory analysis, and computer processing to crime scene management and evidence retrieval. This research is based on a thorough review of scholarly literature and a …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 2, 2026 Read article
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Systematic Analysis of the Pharmacological Properties of Different Plant Parts of Madhuca sp.
Abstract: Madhuca sp., a perennial tree belonging to the Sapotaceae family, is widely distributed across South and Southeast Asia. It holds considerable value across the food, beverage, and pharmaceutical sectors. The growing interest among cultivators, agronomists, and industry stakeholders stems from the diverse bioactive potential documented across different parts of the plant, including the bark, leaves, seeds, and flowers. Traditional and emerging evidence points to a wide spectrum of pharmacological actions, …
Published in Research & Reviews : Journal of Botany · Vol. 15, Issue 2, 2026 · pp. 1–11 Read article
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Biochemical Biomarkers as a Tool in Chromium Induced Toxicity to Green Tiger Prawn, Penaeus semisulcatus (De-Haan, 1844)
Abstract: Estuarine ecosystem and its biodiversity are at higher risk due to coastal contamination by heavy metals and conservation of biodiversity can be accomplished by utilizing biomarkers of pollutant at different exposure levels. In the present study, chronic toxicity test was conducted to evaluate the antioxidants and enzymes as the possible biomarkers in Green Tiger Prawn, Penaeus semisulcatus. The chronic endpoint value (MATC), no-observed effect concentration (NOEC), and low-observed effective concentration …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 4, Issue 2, 2014 · pp. 1–12 Read article
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Strategies in the Delivery of Nonsteroidal Antiinflammatory Drugs
Abstract: Non-steroidal anti-inflammatory drugs [NSAIDs]. are widely used for the management of pain, inflammation, and fever. However, their effectiveness is often limited by gastrointestinal side effects such as ulceration and bleeding, as well as systemic complications including renal toxicity and cardiovascular risks. To address these challenges, various strategies have been developed to improve the delivery of NSAIDs, aiming to enhance their therapeutic efficacy while minimizing adverse effects. This abstract provides an …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 44–61 Read article
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Pneumatic Car: Solution to Fossil Fuels
Abstract: AbstractUse of conventional source of energy such as petrol, diesel etc. has rapidly affected the environment by means of rapid emission of greenhouse gases such as NOx, SOx,CO2 etc. These modern sources of energy are readily available thus their consumption has increased over the years and it is assumed that after 30 years these conventional sources of energy will be completely exhausted from the modern arena, also there will be …
Published in Journal of Industrial Safety Engineering · Vol. 5, Issue 1, 2018 · pp. 18–27 Read article
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Phytochemical, Pharmacological and Toxicological Studies of Solanum americanum: A Systemic Review
Abstract: Solanum americanum, a plant widely used in folk medicine, has recently gained attention in the scientific community due to its diverse therapeutic potential. The bioactive compounds found in different plant parts, such as alkaloids, flavonoids, and tannins, have significant medicinal effects. These compounds exhibit several pharmacological properties, such as antimicrobial, anti-inflammatory, anticancer, and antioxidant effects. However, despite these medicinal benefits, some compounds show significant toxicity to the human body if …
Published in Research & Reviews : Journal of Herbal Science · Vol. 14, Issue 2, 2025 · pp. 52–62 Read article
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Toxic Potential of Carbaryl on Reproductive and Fertility Parameter in Male Wister Albino Rats
Abstract: This study aims to evaluate the adverse effect of carbaryl on reproductive system of male Wister albino rats. Adult male Wister albino rats were orally administered with 50, 100 and 150 mg/kg body weight of carbaryl for 90 days. Animals from each group were sacrificed after the study period. Sperm count, sperm motility, antioxidant assay (SOD, CAT, LPO, and protein carbonyl), Hormones assay histological analysis and fertility parameters were performed …
Published in Research and Reviews: A Journal of Toxicology · Vol. 5, Issue 2, 2015 · pp. 1–6 Read article
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POTENTIAL BIOPRESERVATIVE EFFECT OF ANTIMICROBIAL PEPTIDES OF SEEDS OF Vigna unguiculata (Cow Pea) ON Hibiscus sabdariffa L. (Roselle) Calyces (Zobo) DRINK
Abstract: Natural and efficient food preservatives are in greater demand because of growing concerns about the safety and quality of processed beverages. Antimicrobial peptides have emerged as promising natural substitutes for synthetic preservatives, boasting advantages like wide-ranging activity and reduced toxicity. In this research, we investigate the inhibitory effects of these peptides against common spoilage microorganisms in 'Zobo' drink. Peptides were extracted and purified from germinated Vigna unguiculata) seeds harvested on …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 14, Issue 1, 2025 · pp. 26–41 Read article
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Review on Histological and Functional Effect of Alcohol on Liver and Kidney
Abstract: Alcohol consumption represents the third largest risk factor for disease burden in most countries of the world. The purpose of this review is to give a comprehensive report of the existing data on the potential adverse effects of alcohol on liver and kidney toxicity. We used 82 different published materials for the compilation of this review article. The Google search engine was used for accessing published materials from databases like …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 7, Issue 2, 2018 · pp. 49–62 Read article
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Polymer Nanocomposites As Emerging Platforms in Pharmaceutical Nanotechnology
Abstract: Nanotechnology allows the handling of materials in the 1–100 nm range, where distinct physicochemical phenomena, including quantum effects and higher surface-to-volume ratio, enable disruptive uses in pharmaceuticals and biomedicine. Significant challenges in solubility, stability and targeted biodistribution of therapeutics can be overcome by incorporating nanostructured polymers and polymer-based composites into drug delivery systems. PLGA nanoparticle and other nanocarriers, such as PLGA micelles, dendrimers, and hydrogels, have revealed promising effects on …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 268–278 Read article
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Toxicity Evaluation of a Few PAHs on a Local Freshwater Fish—Rasbora daniconius
Abstract: Polycyclic Aromatic Hydrocarbons (PAHs) have become ubiquitous pollutants of water resulting mainly from petroleum products. These are absorbed into the living systems and converted into secondary metabolites which show bioaccumulation in the living systems and have several deleterious effects on them. The present study attempts to evaluate toxicity of two such PAHs— Naphthalene and Anthracene—on the freshwater fish, Rasbora daniconius, using pure PAHs dissolved in dichloromethane. LC50 values were seen …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 1, 2020 · pp. 42–46 Read article
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A Unique Insight on Detoxification and Inactivation of Metal Toxicity in Herbal-Metal Preparations in Siddha System
Abstract: Metal chelating property of various time tested siddha herbs were tested individually vis a vis Phyllanthus emblica, Embelia ribes, Elettaria cardamomum, Withania somnifera, Corollocarpus epigaeus, Centella asiatica, Celastrus paniculatus, Smilax chinensis, Psoralea corylifolia, Solanum trilobatum and Indigofera aspalathoides. Most of the plants showed metal chelating effect suggesting their role in in-activating metal toxicity. Use of these herbs along with metal preparation may offer some value in reducing toxicity due to …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 2, Issue 2, 2015 · pp. 13–17 Read article
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Preparation and evaluation of Herbal cosmetic
Abstract: In this investigation herbal cosmetics namely Liquorice cold cream and Catechu shampoo were prepared and evaluated. This investigation for herbal cosmetics was done for reducing toxicity for long term use in skin effectively using various herbal ingredients prepared in the laboratory such as tulsi extract, catechu extract, liquorice extract, and clove water. Liquorice cold cream provides numerous skincare benefits , thanks to liquorice extract's properties: It hydrates and nourishes dry …
Published in Recent Trends in Cosmetics · Vol. 1, Issue 2, 2024 · pp. 26–43 Read article
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Study Review: Molecular Mechanisms of Nanoparticle-Cell Interaction – Implications for Drug Delivery and Toxicity
Abstract: The application of nanoparticles in drug delivery and biomedical therapies holds great promise, yet their interaction with cells and the underlying molecular mechanisms remains areas of active research. This study explores the molecular mechanisms of nanoparticle-cell interactions, focusing on the effects of gold nanoparticles (AuNPs) and silica nanoparticles (SiNPs) in human cancer cell lines (HeLa and MCF-7). The study examines how nanoparticles are internalized by cells, their impact on cellular …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 · pp. 31–40 Read article
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Green Fabrication of Glutaraldehyde-Crosslinked Chitosan/PVA Biocomposite for Heavy Metal Removal from Wastewater
Abstract: Chitosan (CS) and Polyvinyl alcohol (PVA) are polymers that possess biodegradable, biocompatible, and non-toxic properties, making them suitable for wastewater treatment applications. The primary objective of this research is to chemically modify chitosan in a novel manner to enhance its ability to remove hexavalent chromium Cr(VI) from aqueous solutions. In this study, a composite material was synthesized by crosslinking PVA and CS with glutaraldehyde (GA), resulting in the formation of …
Published in Journal of Water Pollution & Purification Research · Vol. 12, Issue 3, 2025 · pp. 59–83 Read article
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Green Solvents in Synthesis of Schiff’s Base: A Comprehensive Review of Sustainable Approach
Abstract: The synthesis of Schiffs & bases is a fundamental process of organic synthesis that traditionally involves using hazardous organic solvents. These solvents pose significant risks to both the environment and human health due to their toxicity, volatility, and persistence in nature. These negative effects of organic solvents have led to the development of greener and more sustainable alternatives that aligns with the principles of Green Chemistry. This review paper aims …
Published in Emerging Trends in Chemical Engineering · Vol. 11, Issue 3, 2024 · pp. 30–40 Read article
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Harnessing the Bioactive Potential of Calotropis gigantea and Calotropis procera
Abstract: The medicinal plants of the Apocynaceae family Calotropis gigantea and Calotropis procera have gained more and more interest as source of bioactive molecules for biomedical applications like cancer therapy. They have various pharmacological activities, which are believed to be linked to various phytochemical constituents such as cardenolides, cardiac glycosides, flavonoids, triterpenoids, steroids, phenolic compounds, alkaloids, and proteins in their latex. The recent molecular and cellular studies show that extracts and …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 2, 2026 Read article