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134 articles for “Novel Treatments”
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Comprehensive Review on Antimicrobial based Hydrogel for Wound Healing
Abstract: Chronic wounds present a significant clinical challenge due to their prolonged healing time, high risk of infection, and frequent recurrence. The development of novel wound dressings with both healing and antimicrobial properties is essential for effective wound management. This study focuses on the formulation and evaluation of an antimicrobial drug-loaded hydrogel designed to promote chronic wound healing. Chronic wounds are a growing concern in healthcare, often taking weeks or even …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 · pp. 72–88 Read article
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Synthesis and Evaluation of New Coumarin Derivatives for Inflammatory Bowel Disease Against DSS-Induced Acute Ulcerative Colitis Mice Model
Abstract: Objective: The discovery of the now numerous mouse models of intestinal inflammation has increased our understanding of the intestinal inflammation that occurs in inflammatory bowel disorders (IBD). This study aimed to investigate the use of a standardized animal model subjected to coumarin derivative treatment, and the action of synthesized molecule administration of dextran sodium sulphate (DSS)- induced colitis in experimental mice. Materials and Methods: We generated a variety of unique …
Published in Journal of Modern Chemistry & Chemical Technology Read article
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To Investigate Hormonal Fluctuations in Male Rattus norvegicus after Treatment with 50% Methanolic Extract of Acacia arabica
Abstract: The use of medicinal plants in traditional and modern medicine has garnered significant interest for their therapeutic potential. Acacia arabica, commonly known as babul, is renowned for its bioactive compounds and diverse pharmacological properties. This study investigates the hormonal fluctuations induced by 50% methanolic extract of Acacia arabica in male Rattus norvegicus, aiming to explore its potential as a male contraceptive. Male contraception remains limited primarily to condoms and vasectomy, …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 3, 2024 · pp. 28–38 Read article
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A Split and Merge UNet: A Deep Learning Assisted UNet Model to Segment Corpus Callosum of Brain for Automatic Autism Detection
Abstract: In recent years, deep learning techniques have shown remarkable performance in various image analysis applications, particularly in the domain of medical image processing. Among these, image segmentation plays a critical role, as it helps in isolating and analyzing specific regions within medical images. The proposed study focuses on segmenting the corpus callosum, a vital structure in the human brain, using a novel optimization technique known as the Split and Merge …
Published in Journal of Multimedia Technology & Recent Advancements · Vol. 11, Issue 3, 2024 · pp. 1–9 Read article
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Early Alzheimer’s Disease Prediction Using Vision Transformers and Attention-Guided MRI Analysis
Abstract: Alzheimer’s Disease (AD) continues to be a major global health concern, with early detection being crucial for effective intervention. While conventional machine learning and convolutional neural network (CNN) approaches have made notable progress in automated AD diagnosis using MRI data, they often struggle with capturing long-range dependencies and maintaining spatial contextual awareness. In this research, we propose a novel framework using Vision Transformers (ViTs) for early Alzheimer’s prediction from 3D …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 16, Issue 1, 2026 · pp. 30–40 Read article
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Deciphering the Pathophysiology of Migraine: Understanding Trigeminovascular System Activity and the Importance of the Gut-Brain Axis
Abstract: Migraine, a prevalent and disabling neurological condition, manifests in distinct phases: premonitory, aura, headache, postdrome, and interictal. Being a primary contributor to adult disability, it presents a substantial economic challenge on a global scale. Even with extensive research spanning centuries, the complete grasp of its root causes continues to evade us. This intricate neurovascular disorder primarily involves local vasodilation of intracranial and extracerebral blood vessels, coupled with simultaneous stimulation of …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 50–61 Read article
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Engineered Polymer Composites for Non-Surgical Lip Posture Correction in Facial Paralysis
Abstract: Facial paralysis presents significant functional and aesthetic challenges, particularly through lip posture deficits such as drooping and drooling, often inadequately addressed by traditional surgical or drug-based interventions, especially in debilitated patients. This study explores the application of engineered polymer composites in a novel, non-surgical lip posture corrector designed to statically suspend and correct lip position without requiring surgical or dental support. The device utilizes a precisely formulated blend of polymethylmethacrylate …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 Read article
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Radio Frequency Next-Generation Advances
Abstract: Radio frequency (RF) technology is a key enabler for modern wireless communications, driving the evolution of telecommunications, healthcare, aerospace, defence and the Internet of Things (IoT). Faster, more reliable and energy-efficient communication systems have been developed at a rapid pace due to recent discoveries in RF engineering. This article discusses novel advancements in RF technologies including enhanced antenna design, millimeter-wave communication, software defined radio, smart spectrum management, and RF-based sensor …
Published in International Journal of Radio Frequency Innovations · Vol. 4, Issue 1, 2026 Read article
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Precision Medicine for Neurofibromatosis Type 1: Progress and Prospects in Drug Discovery
Abstract: Objective: The development of neurofibromas, café-au-lait spots, and other neurological problems are the hallmarks of neurofibromatosis type 1 (NF1), a hereditary disorder. The dearth of efficacious pharmaceutical therapies underscores the need for novel therapeutic approaches, even in the face of clinical variability. Through very accurate prediction of the binding affinity of possible therapeutic drugs with the target protein, the computational technique known as “molecular docking” has become a potent tool …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 01–15 Read article
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Exploring Type-II Diabetes Potential of Phyto-Derived Carbon Dots
Abstract: The integration of phytoconstituents with carbon dots (C-dots) presents a novel and sustainable approach to the development of nanotherapeutics for type 2 diabetes mellitus (T2DM). C-dots, zero-dimensional carbon-based nanomaterials, exhibit unique physicochemical properties including high fluorescence, tunable surface chemistry, biocompatibility, and low toxicity. Their ability to enhance the solubility, bioavailability, and targeted delivery of poorly soluble phytochemicals renders them highly suitable for biomedical applications. This study explores the synthesis of …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 08–25 Read article
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Brain Tumor Detection Using RestNet50 Architecture
Abstract: This paper presents a novel deep learning model for brain tumor diagnosis from MRI scans on the basis of ResNet50 with some modifications. Optimizing the modified layers and pre-trained ResNet50 for improved diagnostic accuracy and reliability in real-world clinical settings is one of the key contributions of this paper. The model was trained on an extremely well-balanced data of 2,577 MRI scans, which were split equally among the tumor and …
Published in Current Trends in Signal Processing · Vol. 15, Issue 2, 2025 · pp. 1–13 Read article
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In Silico Screening of Terminalia chebula Phytocompounds as Potential Inhibitors of NTCP and DDB1 in Hepatitis B Virus Infection
Abstract: Hepatitis B virus (HBV) infection is a major global health concern, and chronic carriers are at risk of developing cirrhosis, hepatocellular carcinoma (HCC), and even death. Existing treatments can effectively inhibit viral replication, but they achieve little eradication of the virus because of covalently closed circular DNA (cccDNA) retention. In this investigation, bioactive compounds of Terminalia chebula, a plant known for its hepatoprotective and antiviral properties in traditional medicine, were …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 1, 2026 · pp. 33–44 Read article
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Machine-Learning-Assisted Development of Polymer-Biochar Composite Adsorbents for the Removal of Heavy Metals from Gomti River Water
Abstract: Rapid urbanization, industrial discharge, and agricultural runoff pose a significant threat to freshwater sustainability and public health. Within these ecosystems, polymer pollutants—such as microplastics, nanoplastics, synthetic fibres, and additive residues—have emerged as persistent vectors capable of adsorbing and transporting toxic heavy metals. Because these polymeric contaminants dynamically interact with conventional aquatic parameters to alter pollutant mobility and ecological risk profiles, there is an urgent need to transition from passive environmental …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 72–95 Read article
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Application of Drug Delivery using Nano- technology to Cure Mental Disorders (Schizophrenia)
Abstract: Nanotechnology involves the manipulation of the count at an atomic scale to create novel systems, materials, and devices. This groundbreaking era holds substantial potential for scientific development across various domain names, which includes manufacturing, patron items, electricity, substances, and remedies. In current times, the sphere of prescribed drugs has witnessed a brilliant surge in the usage of nanotechnology for the improvement of revolutionary medications. Schizophrenia, a neuropsychiatric disorder affecting the …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 1, 2024 · pp. 51–65 Read article