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319 articles for “Drug delivery systems”
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Controlled Release Drug Delivery Using 3D Printing Techniques: A Current Scenario In Personalized Medicine
Abstract: Three-dimensional (3D) printing is particularly influencing the pharmaceutical manufacturing sector in the creation of controlled release drug delivery systems. This technology enables the precise fabrication of personalized medicines with tailored drug release profiles, dosages, and geometries, marking a significant advancement over traditional mass production methods. An array of 3D printing techniques, including extrusion-based, powder-based, and others, can be used to build complex dosage forms that regulate drug release through processes …
Published in Trends in Drug Delivery · Vol. 12, Issue 3, 2025 · pp. 28–43 Read article
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Use of CRISPR/Cas9 in Delivery System with Nanotechnology Concept
Abstract: In this emerging era of science and technology development, the use of drug delivery concept has made possible to cure several health problems, but for certain genetic diseases like Sickle cell anemia, chronic diseases like cancers, Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)/CRISPR associated system (Cas) gene-editing system is here as a promising tool to cure them by doing certain gene manipulation in specific gene area causing the disease. However, …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 12, Issue 2, 2022 · pp. 16–23 Read article
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A Comprehensive Review: Emerging Nanotechnology in Cancer Drug Delivery
Abstract: Nanotechnology has become a groundbreaking strategy in cancer therapy, especially in drug delivery systems, offering improved treatment effectiveness while minimizing the adverse effects associated with traditional methods. This review presents an in-depth analysis of recent progress in nanotechnology for cancer drug delivery, emphasizing the design, mechanisms, and practical applications of nanoparticle-based systems. Nanoparticles, such as liposomes, dendrimers, and gold nanoparticles, offer unique advantages, including improved drug solubility, targeted delivery to …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 1, 2025 · pp. 24–33 Read article
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A Review on: Oral Thin Films: A New Approach to Effective and Easy Drug Delivery
Abstract: Oral Thin Film (OTF) is an advance drug delivery system in which drug is incorporated into dissolvable strip and place in oral cavity for rapid absorption. OTF is useful for patient such as pediatric and geriatric who have difficulty swallowing pills. It provides rapid action, precise dosage and improved bioavailability. OTFs consist of fast-dissolving films, extended-release films, and mucoadhesive films for various therapeutic applications. The manufacturing processes of OTFs such …
Published in Trends in Drug Delivery · Vol. 11, Issue 3, 2024 · pp. 22–41 Read article
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Microneedles: A New Concept for Transdermal Drug Delivery
Abstract: Transdermal delivery keeps a promising carrier in the transport of drugs which get direct access across the skin deep into the systemic circulation. Advantages of transdermal drug delivery system include improved patient compliance, less dose of biologicals, avoidance of gastric irritation as well as the elimination of the first-pass metabolism. Microneedles can be used to improve transdermal drug delivery for some drugs. In this study, we focus on methods of …
Published in Trends in Drug Delivery · Vol. 6, Issue 3, 2019 · pp. 22–29 Read article
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A Review on Novel Emulsification Technique: A Nanoemulsion
Abstract: Kinetically stable and isotropic system of submicron size range is the nanoemulsion. In this system two immiscible liquids are mixed together to form a single-phase system with the identical concentration and ratio of surfactant and cosurfactant. Nanoemulsion droplet sizes fall typically in the range of 20- 200 nm. Some literature suggest this range below 100 nm with shows narrow size distribution. In this review, major focus is given on the …
Published in Trends in Drug Delivery · Vol. 3, Issue 2, 2016 · pp. 25–34 Read article
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Microemulsion: Novel Carrier for Drug Delivery
Abstract: Since the discovery of much novel formulation belongs to the lipid based drug delivery system, the handicapped property of drug molecule reverted to the fittest, doable and easily delivered with strategies of improving bioavailability and depleting dose of the same. Microemulsion system is clear, stable, isotropic mixture of oil, water and Smix (Surfactant and co-surfactant mixture), frequently in combination with a co-solvents. To date microemulsions have been shown to be …
Published in Trends in Drug Delivery · Vol. 3, Issue 1, 2016 · pp. 1–18 Read article
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Development of Polymersomes as Macromolecular Platforms for Nanomedicine
Abstract: The conventional method of drug delivery is plagued with instability, low targeting and low bioavailability. A solution to these shortcomings is the use of polymersomes, artificial vesicles that are produced through self-assembly of amphiphilic block copolymer, and they are suggested as universal nanoscale carriers. They have stiff, tunable membranes (thickness = 2–50 nm) due to accurate control of polymer chemistry, chain length, and hydrophilic mass fraction (f), which allows predictability …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 · pp. 71–89 Read article
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Formulation and Development of Gastroretentive Hydrogels of Glipizide
Abstract: The aim of the present study was to develop a pH sensitive gastroretentive drug delivery system for an antidiabetic drug glipizide, based on gas formation technique using 32-factorial design, in order to prolong the gastric residence time and increase the overall bioavailability of the dosage form, since the absorption is erratic in diabetic patients. The system consists of the drug, glycol chitosan (5% w/w) and aqueous PVA solution (10% w/w) …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 4, Issue 1, 2017 · pp. 1–7 Read article
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In Vitro–In Vivo Correlation (IVIVC): A Strategic Tool in Drug Product Development
Abstract: In a recent era many concepts are dealing as an emerging tool for the drug delivery application like Biopharmaceutical Classification System (BCS), In vitro and In vivo study, and Bioavailability/Bioequivalence (BA/BE) study etc. To determine Therapeutic efficiency in vitro is not enough so the concept of In vitro-In vivo correlation (IVIVC) is playing as an convincing correlation with this for concept of pharmaceutical dosage forms have been a main focus …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 3, Issue 3, 2016 · pp. 31–54 Read article
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Design And Evaluation Of Meloxicam Tablet For Colon Cancer
Abstract: Meloxicam, recognized as a preferential COX-2 inhibitor, has emerged as a promising chemopreventive agent for colorectal cancer. Leveraging its local and targeted action on the colon, Meloxicam proves to be a formidable component in the prevention of colorectal malignancies. This study aims to innovate by formulating and evaluating a targeted tablet delivery system for Meloxicam, emphasizing site-specific and instant drug release in the colon, thereby maximizing its therapeutic efficacy in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 10, Issue 3, 2023 · pp. 1–7 Read article
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A Review on Nose to brain Drug Delivery
Abstract: Nose to Brain drug delivery is very important drug delivery to enter drug molecule inside of brain. There are various severe disease like Parkinson disease, Alzheimer, depression and many more disease associated with brain it can be easily recover with the nasal route. Different type of nerve present in the nasal cavity which absorb the drug and hence easily enter into the brain. There are various barrier for other drug …
Published in Trends in Drug Delivery · Vol. 7, Issue 3, 2020 · pp. 6–10 Read article
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Polymer Chemistry and Its Applications in Pharmaceutical Composite Formulations
Abstract: Polymer chemistry plays a critical role in pharmaceutical formulations, particularly in enhancing drug stability, bioavailability, and controlled release. Polymers are widely utilized in drug delivery systems. Polymers are widely used in pharmaceutical sciences for drug delivery, controlled release, and stability enhancement. This paper explores the role of polymers in the extraction and formulation of glycyrrhetinic acid from Glycyrrhiza glabra, a bioactive compound. Various polymer-based extraction and purification techniques are discussed, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 216–221 Read article
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Polymer Chemistry-Driven Approaches for Improved Therapeutic Delivery
Abstract: Polymer chemistry has revolutionized pharmaceutical technology by enabling the development of advanced drug delivery systems with improved precision, stability, and therapeutic outcomes. This review explores the role of polymer design, synthesis, and functionalization in the development of responsive and targeted drug carriers. Emphasis is placed on various types of polymers—biodegradable, synthetic, natural, and stimuli-responsive—and their suitability for drug delivery platforms such as nanoparticles, micelles, hydrogels, dendrimers, and implants. The physicochemical …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 Read article
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Graphene-Polymer Nanocomposites for Drug Delivery Applications
Abstract: Graphene-polymer nanocomposites (GPNCs) have gained significant attention in drug delivery due to their exceptional physicochemical properties, including high surface area, mechanical strength, tunable functionality, and biocompatibility. These nanocomposites integrate graphene derivatives, such as graphene oxide (GO) and reduced graphene oxide (rGO), with biocompatible polymers to enhance drug loading efficiency, stability, and controlled release. Various natural (chitosan, alginate) and synthetic (PLGA, PEG, PCL) polymers are used to functionalize graphene, enabling targeted …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 362–374 Read article
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Formulation Development of Anti-psoriatic Topical Babchi Oil Emulgel
Abstract: AbstractPsoriasis is an inflammatory condition associated with painful, itchy, scaly skin and disfiguring skin lesions. It is an autoimmune disease that appears on the skin. The immune system plays a key role in psoriasis. The lack of possible cure and associated disadvantages in allopathic medicines has led to extensive research in natural products with anti-psoriatic activity. Psoralea corilyfolia (Babchi oil) was found to be efficacious and cheap anti-psoriatic drug with …
Published in Research & Reviews : Journal of Herbal Science · Vol. 2, Issue 2, 2013 · pp. 12–25 Read article
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AQUASOMES: A Vesicular, Self-assembled Ceramic Nanoparticulate Drug Carrier
Abstract: Nano-biopharmaceutics involves delivery of biopharmaceutical product through different biomaterials like multi-functional nanoparticles, quantum dots, aquasomes, super-paramagnetic iron oxide crystals, and liposomes dendrimers. Aquasomes are considered as one of the most recently developed delivery systems for bioactive molecules like peptides, proteins, hormones, antigens and genes to specific sites. Aquasomes have a spherical shape and a particle size of 60–300 nm. These are three layered self-assembled nano-particulate carrier system. This three-layered structure …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 3, 2025 · pp. 1–14 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Sustainable Biomedical Applications
Abstract: Liposomal drug delivery has evolved into a viable approach in modern pharmacology thanks to its enhanced bioavailability, reduced systemic toxicity, and targeted drug release. Conventional liposomes have limited stability, medicine leakage, and short circulation times among other problems. Overcoming these limits, the inclusion of nano-polymers into liposomal formulations has transformed medication delivery. Thorough research has been done on the potential of nano-polymers including chitosan, hyaluronic acid, polyethylene glycol (PEG), and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 420–432 Read article
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An Overview of Rheumatoid Arthritis: Enhancing Current Treatment Strategies Using Nanomaterials
Abstract: Background and Aim: Rheumatoid arthritis (RA) is a persistent and progressive autoimmune disease commonly affecting many people worldwide that severely attacks joints, leading to inflammation, cartilage destruction, and bone erosion. Exhaustive research on RA over the years has significantly contributed to a better understanding of the disease's causes, mechanism, progression, and treatment. Several therapies are available for its management, including anti-inflammatory and disease-modifying antirheumatic drugs. This present review aims at …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 25, Issue 1, 2023 · pp. 50–78 Read article
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Formulation and Characterization of Mesoporous Nanoparticulate Drug Delivery Platform
Abstract: The aim of this study was to synthesize and characterize mesoporous silica nanoparticles, namely, SBA-15 (Santa Barbara Amorphous) and MCM-41 (Mobile Crystalline Material) as a drug delivery platform. These MSNs have been synthesized using triblock copolymer F 127, cetyl trimethyl ammonium bromide (CTAB) as a co-surfactant and tetraethyl orthosilicate (TEOS) as a silica precursor. The synthesized MSNs were characterized by scanning electron microscopy (SEM), powder X-ray diffraction (PXRD), particle size …
Published in Trends in Drug Delivery · Vol. 2, Issue 1, 2015 · pp. 21–27 Read article