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136 articles for “Clinical validation”
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Study to Assess the Effectiveness of Teaching Program on Knowledge Regarding Management of Patients with Regenerative Orthopedics Procedures Among Orthopedic Nurses at Selected Orthopedic Departments
Abstract: Regenerative therapy is an emerging treatment approach in medical science. It focuses on the use of stem cell therapy, biological treatments, tissue engineering, platelet-rich plasma, prolotherapy, and nutraceutical supplements to replace or restore dysfunctional structures or organs. Regenerative therapy emphasizes the body’s natural healing process; it supports physiological healing mechanisms and repairs damaged tissues. It is a minimally invasive approach with expanding applications across various medical fields, including surgery, degenerative …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 3, Issue 2, 2025 · pp. 7–11 Read article
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Psychological Profile of Patients Undergoing Hemodialysis and Its Association with Physiological Parameters
Abstract: Background: End-stage renal disease (ESRD) is a chronic, progressive condition requiring maintenance hemodialysis, which imposes substantial physiological, psychological, and social burdens on patients. While physiological indicators are routinely monitored during treatment, the influence of psychological factors on these indicators and patients' quality of life remains inadequately explored, particularly in the Indian context. Objective: To investigate the relationship between psychological variables (depression, anxiety, illness intrusiveness, and quality of life) and physiological …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 2, 2026 · pp. 40–48 Read article
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Exploring the Effects of Yogic Meditation on Stress, Anxiety, and Cardiovascular Health: A Prospective Cross-Sectional Cohort Study at Desh Bhagat Hospital
Abstract: Background: Stress and anxiety are significant risk factors for cardiovascular disorders, with growing evidence suggesting that yogic meditation can mitigate these effects. This prospective cross-sectional cohort study was conducted to evaluate the impact of yogic meditation on stress, anxiety, and cardiovascular parameters among patients attending Desh Bhagat Hospital. Methods: A cohort of 350 patients was recruited, comprising individuals presenting with elevated stress, anxiety, or cardiovascular conditions. Participants underwent a guided …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 1, 2025 Read article
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The Renaissance and Resilience of CB1 Reverse Agonists: From Central Liabilities to Peripheral Promise
Abstract: Building upon these foundational insights, current research has increasingly focused on refining the pharmacological profile of CB1 reverse agonists to maximize therapeutic benefit while minimizing central adverse effects. The adverse neuropsychiatric outcomes associated with first-generation agents such as Rimonabant including anxiety, depression, and suicidal ideation highlighted the critical role of central CB1 receptors in mood regulation. Consequently, drug development strategies have shifted toward peripherally restricted CB1 reverse agonists that exhibit …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 30–35 Read article
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A Study to Assess the Awareness of the Breast Cancer Screening Among Teacher Training Students in Selected Teacher Training Institutions at Mysuru with the View to Conduct Educational Program
Abstract: Background: Cancer is one of the major causes of death both in developed and developing countries. Breast cancer is defined by the uncontrollable proliferation of cells within the breast, encompassing different forms of cancer that impact the breast tissue. The majority of breast cancer cases manifest as painless lumps, while a smaller percentage may exhibit additional symptoms. Breast cancer is amenable to almost complete care if detected in its early …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 17–31 Read article
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Exploring Challenges in Clinical Learning and the Impact of Structured Teaching on Infection Control Knowledge and Attitudes Among Nursing Students
Abstract: Living a healthy lifestyle is essential for preventing chronic diseases and maintaining physical, psychological, and social well-being. The present study, titled “Exploring Challenges in Clinical Learning and the Impact of Structured Teaching on Infection Control Knowledge and Attitudes among Nursing Students” aimed to address key challenges faced by nursing students and evaluate the impact of a structured teaching program. The study employed a quantitative research approach using a pre-experimental design …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 1, 2025 · pp. 42–47 Read article
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Anti-hyperglycemia Effects of Plant Secondary Metabolites Towards PKA/CREB Pathway Activation in Diabesity
Abstract: Objective: Diabesity, the amalgamation of diabetes and obesity, presents a significant global health challenge. This research carefully examines how plant secondary metabolites influence glucose regulation in diabetes using the PKA/CREB pathway, paying particular attention to diabesity—the combination of diabetes and obesity. Understanding the complex ways in which these metabolites affect metabolic health will help to identify new treatment approaches for managing diabetes and its associated problems. By conducting a thorough …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 33–50 Read article
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An Improved Power Line Interference Reduction Approach Based on Combination of Mirror Extension and IIR filtering Through a Data Driven Mechanism
Abstract: Electrocardiogram (ECG) is a clinical sign monitoring measurement of the cardiac abnormalities. Like other biomedical signals, the ECG signal is also contaminated by various kinds of noise and artifacts such as power line interference, base line wandering, muscle artifacts and electrode artifacts. The present paper proposes a scheme for power line interference (PLI) reduction from ECG signal. It makes use of the concept of mirror method, empirical mode decomposition (EMD) …
Published in Current Trends in Signal Processing · Vol. 7, Issue 2, 2017 · pp. 13–21 Read article
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IoT-Enabled Flexible Polymer Sensors for On-Body Health Monitoring and Real-Time Data Transmission
Abstract: Wearable health monitoring systems have grown increasingly vital in shifting care beyond clinical settings, yet many existing technologies remain hamstrung by rigid substrates and unreliable data streaming, impeding continuous and comfortable physiological assessment. Despite advances in flexible materials, most current sensor platforms suffer from limited mechanical endurance, signal instability under dynamic conditions, or an inability to sustain real-time wireless transmission. This work addresses those deficiencies by introducing a fully integrated, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 188–200 Read article
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Advancing Cancer Vaccine Development through CRISPR/Cas9 Technologies and Future Opportunities
Abstract: The advent of CRISPR/Cas9 genome editing has revolutionized the cancer immunotherapy market, offering unprecedented precision and versatility in the development of next-generation cancer vaccines. This review examines how CRISPR technologies are being integrated into various stages of cancer vaccine development including neoantigen discovery, dendritic cell engineering, cancer cell reprogramming, and tumor microenvironment modulation. In the area of neoantigen discovery, CRISPR enables rapid identification and validation of tumor-specific mutations, thereby supporting …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 Read article
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Advancements in Analytical Techniques and Validation Methods for Pharmaceutical Tablet Formulations Using HPTLC
Abstract: High Performance Thin Layer Chromatography (HPTLC) is a versatile analytical technique which has been effectively used for pharmaceutical quality control and cost effectively, rapidly, and high throughput analyzed tablet formulations. HPTLC is different from traditional chromatographic methods as multi sample analysis is possible in one run with low consumption of solvent, which are principles of green analytical chemistry. But existing HPTLC is limited in sensitivity, resolution and reproducibility and these …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 3, 2026 Read article
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Non-healing Ulcer Treatment with Unani Formulation Zaroor-e-Qawi: A Case Series
Abstract: Non-healing ulcers (Qurooh-e-Aseeerat-ul-Indamaal) are those ulcers which do not heal by conservative treatment within six weeks. In Indian community its prevalence reported in year 2004 was 4.8 per1000 populations. About 1% of total western population suffers from it. This estimate is likely to increase many folds because of the increasing population of elderly people and the people with uncontrolled diabetes mellitus, arterial and venous diseases. It badly affects the patient’s …
Published in Research and Reviews : Journal of Surgery · Vol. 7, Issue 2, 2018 · pp. 9–14 Read article
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Computational Exploration of Bhrijraj-derived Phytochemicals as Potential Anti-inflammatory Agents: A Molecular Docking Study with Cyclooxygenase-II Complex
Abstract: The molecular docking analysis was meticulously conducted using state-of-the-art computational tools, notably Chimera and Python. These tools were employed to unravel the complex interactions between the identified phytochemicals from Bhrijraj and the target protein, COX-II. The 3D structures of the phytochemicals were prepared with precision using ChemSketch, ensuring accuracy in the subsequent molecular docking simulations. This rigorous approach enhances the reliability and validity of the findings. This research aims to …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 31–37 Read article
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High-Definition Electroencephalography: A New Horizon in Neurological Pathology Research
Abstract: The advent of high-density electroencephalography (HD-EEG) has catalyzed a paradigm shift in the exploration of neurological pathologies. This editorial underscore its transformative potential in elucidating brain dynamics and refining diagnostic approaches for a spectrum of conditions, spanning from epilepsy and dementia to cognitive impairments in preterm infants. Our objective is to optimize the utility of HD-EEG by emphasizing the imperative for methodological homogenization and fostering collaborative endeavors. The remarkable spatial …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 2, 2024 · pp. 15–21 Read article
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Comprehending Ancient Wisdom of Ayurveda: Unveiling Phytochemistry and Molecular Mechanisms of Rasayana Medicine
Abstract: Rasayana medicine is an integral part of ancient medical system of India. In Sanskrit ‘rasayana’ refers to “path of essence” and serves as one of the eight clinical specialties of classical Ayurveda. Rasayana focuses on restoring health by replenishing vital fluids of human body. According to Ayurveda, our physical body constitutes of seven dhatus called ‘Sapthdhatu’, sapth-seven and dhatu-tissues or microchannels. These channels are the pathway through which vital nutrients …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 3, 2025 · pp. 59–67 Read article
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To Compare the Anti-Bacterial Activity of Uva Ursi 200 And Cantharis Vesicatoria 200 In Isolated E-Coli of Different Urine Samples by Kirby Bauer Disc Diffusion Method
Abstract: Background: The most common bacterial infections are Urinary Tract Infections (UTI), primarily caused by Escherichia coli (E. coli), a gram negative bacterium responsible for 80-90% of community-acquired UTIs. The rise of antibiotic-resistant E. coli strains has increased the demand for Homoeopathic remedies. This study explores the antibacterial efficacy of Uva ursi 200 and Cantharis vesicatoria 200, using Kirby-Bauer Disc Diffusion Method, by comparing the Zone of Inhibition (ZOI) of those …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 3, 2026 Read article