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1953 articles for “phosphoinositol-3-kinase pathway” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Recent Developments in Structural Genomics: Uncovering Cellular Functions
Abstract: Structural genomics has become a groundbreaking field for understanding cellular functions by revealing the three-dimensional structures of proteins and other biomolecules. This field combines advanced methods like X-ray crystallography, nuclear magnetic resonance spectroscopy, cryo-electron microscopy, and computational modeling to explore the molecular structure and behavior of cellular components. Recent advances have significantly accelerated the pace of structure determination, bolstered by high-throughput methods and artificial intelligence tools like AlphaFold. These developments …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 30–35 Read article
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The Intersection of Bioinformatics and Cellular Function in Disease Modeling
Abstract: The integration of bioinformatics and cellular biology has revolutionized our understanding of disease mechanisms, offering unprecedented opportunities to model complex biological systems. Bioinformatics is an interdisciplinary field that merges biology, computer science, and statistics, offering advanced tools to analyze vast biological datasets. Cellular functions, including gene expression, protein interactions, and metabolic pathways, form the foundation of physiological and pathological states. Disruptions in these processes can result in diseases like cancer, …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 1–7 Read article
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Comprehensive Study of Least Squares Estimation in Fast Fading MIMO-OFDM Systems
Abstract: MIMO-OFDM technology is now the foundation for modern wireless communication systems, allowing dramatic improvements in spectral efficiency, power efficiency, and transmission rate. On the other hand, the least accurate channel estimation is still a critical task, especially when they are in fast-fading environments. This study gives a comprehensive survey of LSE-based approaches and their applications on different fast-fading channel models for MIMO-OFDM systems. Techniques like Pilot Assisted Channel Estimation (PACE), …
Published in Journal of Microwave Engineering and Technologies · Vol. 12, Issue 1, 2025 · pp. 13–21 Read article
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Diglycidyl Ether of Bisphenol A (DGEBA) Based Epoxy Sizing Agent Induces Surface Polarity in Carbon Fibers†
Abstract: Determination of the chemical structure and composition of the sizing agent is a challenge as its concentration is low, varying in the range from ~0.5 wt.% (for polyacrylonitrile, PAN, based carbon fibers) to ~1 wt.% (for pitch-based carbon fibers). Moreover, such a piece of knowledge is vital for designing compatible polymer matrices to prepare CFRPs for diverse applications. As a result, the sizing layer that is coated on the carbon …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 2, 2024 · pp. 24–34 Read article
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Composition and Structure of Oil Finishing Agent †
Abstract: Use of oil finishing agent is widely used in the process of production of carbon fibers to impart unusual and exceptional strength to the carbon fibers, the key load-bearing component, of the advanced materials, namely, carbon fiber reinforced composites (CFRPs). CFRPs are being widely used in the realm of aeronautics, astronautics, aeronautics, geonautics, sports equipment, and many more. However, quite often, much of the knowledge on the composition of oil …
Published in International Journal of Crystalline Materials · Vol. 2, Issue 1, 2025 · pp. 01–10 Read article
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Particle Size Effect on the Physicochemical Parameters of Water Media in Treatment of Contaminants of AGO and PMS
Abstract: Some of the physicochemical properties of contaminated water media with AGO and PMS was monitored upon the particle size effect and mix ratio. The physiochemical parameters monitored are potassium ammonia, iron and manganese concentration upon the performance of the formulated adsorbent immersed in the salt water and fresh water medium. The investigation demonstrates the occurrence of leaching in the process, which shows that some of the parameters adsorbed by the …
Published in Journal of Petroleum Engineering & Technology · Vol. 14, Issue 2, 2024 · pp. 27–36 Read article
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Evidence-Based Ayurveda Approaches for the Rapid Management of Dyslipidemia
Abstract: Dyslipidemia is increasingly prevalent ain modern society, primarily resulting from imbalances in lifestyle and dietary habits. Elevated levels of triglycerides, however, are associated with an increased risk of cardiovascular diseases and metabolic disorders. Ayurveda, the traditional Indian system of medicine, offers holistic approaches to managing lipid imbalances through dietary regulation, herbal formulations. While it may not directly correspond to a specific disease entity in Ayurveda, it is typically associated with …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 3, 2024 · pp. 63–66 Read article
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Generative Artificial Intelligence with Emphasis on Large Language Models: Review and Current Trends
Abstract: Generative Artificial Intelligence deals with AI systems that generate new content, such as text, and images. It accomplishes this by using data patterns of texts and images that already exist. Generative AI began an era of major advancement in AI, producing more refined and human-like results. Large Language Models, LLMs, is a part of Generative AI with applications in Natural Language Processing such as text generation, translation, summarization, sentiment detection …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 12, Issue 1, 2025 · pp. 40–46 Read article
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Acupuncture in Pain Management: A Neurophysiological and Clinical Perspective
Abstract: Acupuncture, a key component of traditional Chinese medicine, has gained widespread recognition as an alternative therapy for pain management. This practice involves the insertion of fine needles into specific points on the body to influence the flow of energy or "Qi" (pronounced "chee") and restore balance. Mechanistically, acupuncture is believed to modulate pain through neurophysiological pathways, including the release of endorphins, the activation of the body's natural analgesic systems, and …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 Read article
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The Heart of Charani Poetry: An AI Interpretation of Emotional Resonance
Abstract: Poetry has long been a means of expressing emotions and ideas, yet understanding the emotional depth within poems can be challenging using traditional computer-based tools. This study explores the emotions embedded in Charani poems, an important genre in Indian literature, through the lens of their distinctive poetic style. The primary objective is to develop a novel method of analyzing emotions in Charani poetry, contributing to the broader field of emotion …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 12, Issue 1, 2025 · pp. 34–39 Read article
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Investigating the Role of Moisture in the Physical Properties of Harra (Terminalia chebula) Fruit
Abstract: Harra (Terminalia chebula) is known as the “king of medicines” in Ayurveda. Its fruits include astringent, purgative, antibacterial, antifungal, and laxative effects. The behavior of harra fruit is mainly dependent on the moisture present. It affects the harvest, post-harvest machinery, separation, packaging, and transportation of harra fruit. This study focused on T’s physical qualities of chebula fresh fruit at 20%–25% (wb) moisture content, such as 50 fruit mass, length, width, …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 1, 2025 · pp. 11–19 Read article
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Optimization of Bulk Density and Moisture Content in Different Stages of Plantation for the Single Row Manually Operated Vegetable Transplanter for Brinjal and Chilli.
Abstract: The machine used in the experiment was designed for suitability to the pot-type seedlings. In pot-type seedlings, soil in the form of soil block, keeps the roots of the seedling enact and therefore ensures minimum mortality and maximum survival of the seedlings. The compactness and seedling settlement time, before its removal from cage for planting, guides the soil block strength against breakage. The minimum damage of soil block in pot …
Published in Research & Reviews : Journal of Botany · Vol. 14, Issue 1, 2025 · pp. 20–24 Read article
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Enhancing Energy Efficiency in Air Handling Units Through AI Driven Optimization
Abstract: This research explores the implementation of artificial intelligence (AI) in enhancing the energy efficiency of Air Handling Units (AHUs) in manufacturing facilities. The study proposes a comprehensive solution architecture that incorporates temperature and humidity sensors within AHUs, utilizing RS485 for data communication. The collected data undergoes exploratory analysis, which informs the training of a decision tree algorithm, chosen for its accuracy and compatibility with edge gateways. The algorithm's predictions enable …
Published in International Journal of Industrial and Product Design Engineering · Vol. 2, Issue 2, 2024 · pp. 19–28 Read article
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Variables Influencing the Reinforcing Effect of Organoclay in Polymer Nanocomposites
Abstract: This study examines how several factors affect the mechanical and thermal characteristics, such as tensile strength, tensile modulus, impact strength, thermal decomposition temperature, and Vicat softening point tests of poly(vinyl chloride)/organoclay nanocomposites. The variables included three different organoclay loading levels, three different screw rotation speeds, and three different plasticizer contents. A co-rotating twin-screw extruder was used to create the poly(vinyl chloride)/organoclay nanocomposite via the melt intercalation process. The properties of …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 15, Issue 1, 2025 · pp. 55–64 Read article
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Comparative Study on the Growth and Yield of Ganoderma lucidium Mushroom Cultivated on African Peach (Nauclea diderrichii) and Bush Mango (Endospermum medullosum) Sawdust as Substrates
Abstract: This study was conducted to find out which substrate provides for the best artificial development of G. lucidium. Mango (Mangifera indica) leaves were added to the saw dusts of Nauclea diderrichii and Endospermum medullosum, which were both utilized as substrates for growing. The substrates were inoculated with Ganoderma spawn and then exposed and hydrated to start the fruiting process. Three replications of the process were carried out. It was observed …
Published in International Journal of Fungi · Vol. 2, Issue 1, 2025 · pp. 39–45 Read article
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Maximizing Flow and Ensuring Leak Tightness Through Design and Development of a Unidirectional Check Valve
Abstract: The check valve market, valued at USD 6.5 billion in 2024, is expected to grow at a 4.1% CAGR. Challenges in valve seat materials, particularly SS304 and PTFE (Teflon), contribute to a 0.5% leak rate, which leads to helium gas loss, reduced efficiency, and higher operational costs. While various sealing techniques, including hard-on-soft methods, have been explored, few have been applied to poppet check valves. This study focuses on improving …
Published in International Journal of Industrial and Product Design Engineering · Vol. 2, Issue 2, 2024 · pp. 10–18 Read article
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Advancing Capsule Technology: A Comprehensive Review of Formulation Strategies
Abstract: Capsules are a popular and versatile oral dosage form used in drug delivery, offering benefits such as ease of swallowing, taste masking, and improved stability of active pharmaceutical ingredients (APIs). They can be made from gelatin or non-gelatin materials like Hydroxypropyl Methylcellulose (HPMC), Polyvinyl Alcohol (PVA), and starch, catering to dietary, cultural, and sustainability needs. Capsules can be engineered for controlled, sustained, or targeted release, enhancing bioavailability, particularly for poorly …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 44–56 Read article
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Evaluating the Structural Performance of Concrete with Partial Replacement of Fine Aggregate by Plastic Waste
Abstract: This work evaluates the performance of concrete incorporating plastic waste as a partial replacement for fine aggregate, at replacement levels of 0%, 5%, 10%, 15%, and 20%. Various tests were conducted on fresh and hardened concrete to assess workability, strength, and durability. The slump cone and compaction factor tests were used to measure workability, yielding a slump range between 25–30 mm and a compaction factor of 0.98, indicating medium workability. …
Published in Journal of Structural Engineering and Management · Vol. 11, Issue 3, 2024 · pp. 69–75 Read article
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Improved Cooling Effectiveness in Radiators and Heat Exchangers with Nanofluid-Based Technology
Abstract: This study discusses how the process of heat transfer in radiators and heat exchangers can be improved using nanofluids and analysis of computational fluid dynamics. These nanofluids comprise Al₂O₃ and ZnO dispersed in water-based ethylene glycol solutions, and graphene oxide dispersed in water-based solutions, and performance evaluation was done for the range of flow rates 180–420 l/h. And a 3D CAD model was created using the ANSYS Workbench. It was …
Published in Recent Trends in Fluid Mechanics · Vol. 12, Issue 1, 2025 · pp. 31–62 Read article
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Investigation of Process Specifications on Friction Stir Welded Aluminium 5083 and 6082 Alloys
Abstract: Aluminium 5083 alloys were mainly used for naval based applications because of better corrosion resistance feature. Similarly aluminium 6082 alloy being a structurally significant material found its applications in construction sector. Fusion welding of these two heterogeneous alloys is bit hard, since it evolves many defects. Present Investigation deals with two cases of distinct alloys through FSW process. Case 1 represents 31 experimental trails performed by 5 various tool pin …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 1–11 Read article