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706 articles for “sil”
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In Silico Pharmacological Evaluation of Certain Commercially Available Terpenoids As Αlpha-Amylase Inhibitors for The Management of Diabetes Mellitus
Abstract: The objective of this study was to investigate the α-amylase inhibitory activity of certain commercially available terpenoids using in silico docking studies. In this perspective, terpenoids like Abietane, Artemisinin, Carvone, Cucurbitane, Ferruginol, Lupeol, Nerolidol, Retinol, Sabinene, and Zingiberene were selected. Glibenclamide, a well-known antidiabetic drug was used as the standard. In silico docking studies were carried out using AutoDock 4.2, based on the Lamarckian genetic algorithm as the working principle. …
Published in Research and Reviews : Journal of Computational Biology · Vol. 10, Issue 2, 2021 · pp. 1–9 Read article
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In silico Analysis of nsSNPs in the Human ACTN4 Gene associated with a Steroid-Resistant Nephrotic Syndrome
Abstract: The main motive of this study is to discover nsSNPs of ACTN4 gene through various insilico views. ACTN4 is one of the proteins that play a leading role in cellular pathways by altering cytoskeletal behaviour associated with steroid-resistant nephrotic syndrome. Data of ACTN4 was collected from NCBI dbSNP and Uniport KB and further used to explore adverse outcome using SIFT, PolyPhen, PROVEAN and SNAP2.Out of 11 nsSNPs selected in this …
Published in Research and Reviews: A Journal of Health Professions · Vol. 8, Issue 3, 2018 · pp. 43s–52s Read article
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Antibacterial, Cytotoxicity Studies of Azukia mungo (L.) Masam and Correlation with in silico Docking Studies
Abstract: Introduction and Background: Azukia genus plants rich in proteinaceous anti-nutrients like tannins (especially condensed tannins) has been shown to have anti-bacterial activity against Staphylococcus aureus and antineoplastic activity against lung and liver cancer cells. Five types of procyanidins (condensed tannins) have already been isolated from Azukia mungo and structurally elucidated. But its activity against the Methicillin resistant Staphylococcus aureus (MRSA) has not yet been shown. Hence we focus our work …
Published in Research and Reviews: A Journal of Toxicology · Vol. 7, Issue 2, 2017 · pp. 21–31 Read article
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Histopathological Effects of Silver Nanoparticles on Gills and Liver of Freshwater Fingerlings Catla catla (Ham.)
Abstract: Fish is the best biomarker to identify the adverse effect on surroundings. Here, the fingerlings of major carp (Catla catla) were used as a model in the present work to investigate the toxicity caused by silver nanoparticles (AgNPs). The fish exposed to different concentrations of 10 μg/L and 30 μg/L AgNPs for 15 days were sampled at days 5, 10 and 15 for histology. This exposure caused organ injuries, and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 6, Issue 1, 2016 · pp. 18–27 Read article
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Manganese Mercury Thiocyanate Doped Zirconium Silicate Crystal Structure for Photo-Electronic, Electro-Optic and Sensor Applications
Abstract: Manganese mercury thiocyanate is a well-known organometallic crystal prized for its nonlinear optical properties. The high second harmonic efficiency of nearly 18 times that of urea and the wide optical transmittance window (373–2250 nm) of MMTC indicate that this material is an excellent candidate for photonics device fabrication. The metal thiocyanates and their Lewis-base adducts are one of the interesting themes of structural chemistry. For MMTC is a very flexible …
Published in Journal of Materials & Metallurgical Engineering · Vol. 16, Issue 2, 2026 Read article
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In Silico Screening and Evaluation of Some Metabolites from Momordica charantia in the Treatment of Peptic Ulcers
Abstract: Peptic ulcers are also called as or duodenal ulcers or gastric ulcers that are open sores generally develop in the lining of the stomach due to food and climatic factors. H. pylori infections are potentially the most dangerous and are linked to several diseases like diabetes, cancer, cardiovascular diseases, etc. In the present study, in silico screening and evaluation of some metabolites from Momordica charantia like Momorcharin, Momordicin, Metformin, Pioglitazone, …
Published in Research and Reviews : Journal of Computational Biology Read article
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Assessment of Reservoir Storage Capacity and Silt Deposition Using Advanced Instruments: A Case Study
Abstract: Reservoirs on the upstream side of sediment-laden river dams fill with sediment over time, lowering their storage capacity. This research focuses on advanced instrumentation techniques used to analyse storage capacity and estimate the quantity of sedimentation deposited in the reservoir at Kadana Dam, Kadana Village, Mahisagar District, Gujarat, India. During the research investigations, a multi-frequency acoustic system with frequencies of around 33 KHz and 210 KHz was employed to assess …
Published in Journal of Control & Instrumentation Read article
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Nanocrystalline Silver: Synthesis by High-Energy Ball Milling, X-ray Debye Temperature Analysis, and Diverse Applications
Abstract: This research paper presents a comprehensive investigation into transforming micro-sized silver (Ag) powder into nanostructured Ag powder by applying high-energy ball milling. The ball milling process was executed over a total duration of 20 hours, with periodic sampling every 4 hours to monitor the evolving characteristics of the material. The particle size, lattice strain, Debye-Waller factor, and root mean square amplitudes of vibration were calculated by using X-ray powder diffraction …
Published in Journal of Polymer & Composites · Vol. 11, Issue 12, 2023 · pp. 140–148 Read article
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Analysis of Thermo-Mechanical Properties in Cement Mortar Using Synthesized Silicate Microencapsulation of Phase Change Materials by Sol-Gel Process
Abstract: This investigation delves into improving building thermal comfort using microencapsulated phase change materials (PCM@SiO2) in cement mortar. The encapsulation process, achieved via a sol-gel method, envelops PCM in a silicate shell Differential Scanning Calorimetry (DSC) and Fourier-Transform Infrared Spectroscopy (FTIR) were used to confirm the thermal properties and integrity of encapsulated PCM, which showed an encapsulation efficiency of 92.7% and a thermal storage capacity of 99.7%. The study involved the …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 152–160 Read article
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Exploring the Concept of Parental Influence and Its Consequences in Alex Michaelides’s The Silent Patient
Abstract: The present paper explores the relationship between attachment theory, parental alienation (PA), and the Parental Acceptance and Rejection Theory (PART), as illustrated by Theo Faber and Alicia Berenson in "The Silent Patient." The definition of PA and its effects on child development are covered first, with a focus on the importance of attachment types and parental involvement. Echoing the conclusions of attachment theorists and empirical research, the essay emphasizes how …
Published in Recent Trends in Social Studies · Vol. 1, Issue 2, 2024 · pp. 24–29 Read article
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Enhancing Concrete Performance Through Ternary Mixtures: Utilizing SCBA and Silica Fume for Sustainable Construction
Abstract: This study investigates the effects of incorporating Sugarcane Bagasse Ash (SCBA) and Silica Fume (SF) as supplementary cementitious materials on the properties of concrete. Compressive strength, split tensile strength, and water absorption characteristics of ternary blended concrete mixes containing varying proportions of SCBA and SF were examined at curing periods of 7, 28, and 56 days. The results reveal that up to 15% SCBA replacement and 10% SF addition led …
Published in Journal of Structural Engineering and Management · Vol. 11, Issue 1, 2024 · pp. 6–12 Read article
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In Silico Investigation of 2,3-Dihydrobenzofuranfrom Centella asiatica: A Possible Pioneer in the Management of Tetanus
Abstract: Objective: Tetanus toxin (TeNT) is a neuroprotein toxin, the most toxic known. They have three functional domains and are structurally similar. They possess an N-terminal catalytic section (light chain), an internal domain for heavy-chain translocation (HN domain), and a C-terminal receptor binding domain for the heavy chain (Hc domain or RBD). Tetanus, an acute nerve-affecting disease, is provoked by a toxin-producing bacterium called Clostridium tetani. This bacterium is environmental, Gram-positive, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 19–30 Read article
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An in-silico toxicity study of the phytocompounds found in Pongamia pinnata leaves using the ProTox-II web server
Abstract: The aim of the current study was to determine the Insilco toxicity of the phytocompound present in the leaves of Pongamia pinnata. The leaves of Pongamia pinnata have long been used in traditional medicine for their therapeutic properties. Nowadays, herbal toxicity is a common problem caused by incorrect dosage. The FDA reviews the safety and effectiveness of herbal products only in response to patient or health care provider complaints—problems with …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 13, Issue 1, 2024 Read article
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Application Of Silver Nanoparticles On Experimental Wound Infection Of Pseudomonas aeruginosa In Rats
Abstract: This study aimed to evaluate the application of silver nanoparticles on experimental wound infection of Pseudomonas aeruginosa in rats. Infected patients at a private hospital in Baghdad had fifty swab samples taken from their wounds and burns (25 samples in total). These swabs were cultured on primary medium and then routine bacteriological tests were done for identification. Molecular confirmation of bacteria was done by using 16S rRNA gene. The research …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 1–8 Read article
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1D-Nano-Scale Porous Silicon (1D-Psi) as Optical Sensor Device
Abstract: This research article embarks on a thorough experimental inquiry into the detection of kerosene adulteration in petrol, employing a sophisticated one-dimensional microcavity of nano-scale porous silicon (1D-PSMC) sensing device. The significance of this investigation stems from the detrimental consequences of petrol adulteration, which not only aggravates environmental pollution but also jeopardizes the functionality and durability of machinery components, thereby posing significant economic and environmental challenges. The 1D-PSMC, designed to function …
Published in Journal of Polymer & Composites · Vol. 12, Issue 5, 2024 · pp. 69–75 Read article
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Techniques of Atomic Structure Orbit Potential of The Frequency Characteristics of Silicon Element
Abstract: This study explores the technological applications and material integration of semiconductor materials, with a focus on their electronic properties and practical implementations. The investigation primarily addresses four key objectives: analyzing the electronic band structure and density of states (DOS) of semiconductor materials, evaluating the band alignment in heterojunctions, and integrating these materials into practical technological applications. Using a simplified tight-binding model, we compute and plot the electronic band structure of …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 11, Issue 3, 2024 · pp. 16–32 Read article
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In-Silico Studies of Phytochemicals from Allium sativum with H5N1 Protein in Avian Influenza
Abstract: Allium sativum or garlic is a medicinal plant that is reported for its applications in many biological activities, such as its antiviral, antidiabetic, and anti-inflammatory properties, etc. In this paper, the focus has been the identification of potential phytochemicals that can be extracted from Allium sativum that can act as a candidate for drug formation that possesses the capability to inhibit the H5N1 Avian Influenza, a type of highly pathogenic …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 2, 2024 · pp. 50–60 Read article
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In Silico Analysis and Molecular Docking Studies of COX-2 Inhibitors for Anti-Inflammatory Activity
Abstract: Although nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently used to treat pain, lower fevers, and control inflammation, they frequently cause gastrointestinal side effects because they inhibit the COX-1 and COX-2 enzymes. Despite their effectiveness and lack of gastrointestinal side effects, selective COX-2 inhibitors have been linked to cardiovascular risks. To find new COX-2 inhibitors that are safer and more effective, this study uses in silico techniques, such as molecular docking and …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 38–55 Read article
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Study of Ablation Characteristics Carbon Fiber Reinforced Plastic with Silicon Carbide Pores
Abstract: Significant thermal stress is placed on spacecraft during atmospheric re-entry, primarily due to aerodynamic heating. This intense heat can cause severe material damage threatening the spacecraft's structural integrity. To address this challenge, efforts are focused on improving the ablation resistence of spacecraft components. In this work, carbon fiber reinforced plastic (CFRP) composites containing silicon carbide (SiC) holes are explored as a potential solution for enhancing thermal protection system. Four different …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 617–627 Read article
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ANN Approach to Forecasting the Strength of Nano Silica Incorporated Geopolymer Composite
Abstract: Coal and steel industry by-products, such as fly ash (FA) and blast furnace slag (GGBS), have gained significant attention as precursors for geopolymer concrete (GPC) due to their high aluminosilicate content, offering a sustainable alternative to conventional cement. Nano silica (NS), recognized for its exceptional pozzolanic activity and ability to refine microstructure, has shown potential to enhance the mechanical and durability properties of GPC. This study investigates the influence of …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 267–278 Read article