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201 articles for “pathological”
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Plant Bioactive Metabolites and Their Role in the Prevention and Control of Dental Diseases and Infections.
Abstract: The oral diseases, including dental caries and periodontitis, affect masses worldwide, and have historically been managed with synthetic antimicrobials that cause deleterious side effects, leading to mounting bacterial resistance. Consequently, contemporary dentistry is rapidly shifting toward phytomedicine using plant bioactive molecules, such as polyphenols, terpenes, anthraquinones (berberin, eugenol, curcumin, catechins, allicin, and azadirachtin. These compounds offer potent antimicrobial, anti-inflammatory, and tissue-regenerative properties that are crucial for preventing and curing dental …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 47–66 Read article
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Demodex spp. (Acari: Demodicidae) Infestation in Humans: Diagnostic Clues and Therapeutic Approaches to Primary and Secondary Demodicosis.
Abstract: Demodicosis represents an inflammatory dermatosis and adnexal disorder arising from pathologic overgrowth of Demodex mites, primarily Demodex folliculorum and Demodex brevis, which are ubiquitous human ectoparasites residing in pilosebaceous units and eyelid margins. Once regarded as benign commensals, these mites are now recognized as primary drivers or key cofactors in diverse clinical phenotypes, including papulopustular eruptions, pityriasis folliculorum, rosacea-like disorders, blepharitis, meibomian gland dysfunction, and exacerbations of comorbid dermatoses such …
Published in International Journal of Insects · Vol. 3, Issue 1, 2026 · pp. 12–20 Read article
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Early Alzheimer’s Disease Prediction Using Vision Transformers and Attention-Guided MRI Analysis
Abstract: Alzheimer’s Disease (AD) continues to be a major global health concern, with early detection being crucial for effective intervention. While conventional machine learning and convolutional neural network (CNN) approaches have made notable progress in automated AD diagnosis using MRI data, they often struggle with capturing long-range dependencies and maintaining spatial contextual awareness. In this research, we propose a novel framework using Vision Transformers (ViTs) for early Alzheimer’s prediction from 3D …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 16, Issue 1, 2026 · pp. 30–40 Read article
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Extracellular Vesicle-Based Liquid Biopsies: Decoding the Tumor Microenvironment for Precision Oncology
Abstract: The tumor microenvironment (TME) plays a pivotal role in cancer initiation, progression, and therapeutic response. Decoding the TME is, therefore, essential for advancing precision oncology. Extracellular vesicles (EVs), including exosomes and microvesicles, are nanoscale lipid bilayer particles secreted by tumor and stromal cells. They transport a wide range of bioactive molecules, such as DNA, RNA, proteins, lipids, and metabolites, which reflect the dynamic state of the TME. Recent advances in …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 1, 2026 · pp. 43–62 Read article
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Evaluation of New Fungicides for the Management of Mango Anthracnose Disease Caused by Colletotrichum Gloeosporioides
Abstract: A field experiment was conducted at the field of Plant Pathology Division, Regional Agricultural Research Station (RARS), Bangladesh Agricultural Research Institute (BARI), Jamalpur-2000, Bangladesh during February to July 2024 to assessment the efficacy/effectiveness of thirty-five (35) new fungicides received from Pesticide Technical Advisory Committee (PTAC), Bangladesh with control treatment against anthracnose disease of mango. Most of the fungicides under inspection were able to control the disease successfully. This study suggests …
Published in International Journal of Trends in Horticulture · Vol. 3, Issue 1, 2026 · pp. 1–16 Read article
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Comparative Analysis and Future Research Directions in AI in Healthcare: Medical Imaging and Diagnostics
Abstract: Artificial intelligence (AI) is reshaping healthcare, particularly in the areas of medical imaging and diagnostic practice. By using advanced techniques like machine learning and deep learning, AI systems help improve the accuracy, speed, and effectiveness of identifying diseases and analyzing medical images. This paper provides a comprehensive overview of the application of artificial intelligence in medical imaging and highlights its growing importance in clinical diagnostics. It discusses how AI-based systems …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 4, Issue 1, 2026 · pp. 8–13 Read article
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Vitamin D Mitigates Inflammation and Downregulates Importin α3 in Non-Alcoholic Fatty Liver Disease (NAFLD)
Abstract: Background: Pro-inflammatory cytokines, such as TNF-α, IL-1β, IL-6, and IL-8, seem to play a crucial role in the progression of NAFLD as they activate the transcription factor NF-кB. The activated NF-кBp50/RelA subunits are translocated to the nucleus by Importin α3 and Importin α4. Numerous studies have indicated a negative association between NAFLD and vitamin D levels. Low vitamin D levels have been correlated with histological severity, necro-inflammation, and fibrosis in …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 1–16 Read article
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Ayurvedic Management of Vātadhika Vātarakta – A Case Series
Abstract: Vātarakta is a classical disorder described in Ayurveda that arises due to the simultaneous vitiation of Vāta and Rakta, resulting in a pathological condition characterized by mutual obstruction (Āvaraṇa) between these two factors. This complex interaction between Vāta and Rakta leads to a wide spectrum of clinical manifestations, making the condition challenging to diagnose and manage effectively. Among the four types of Vātarakta described in classical texts, Vātādhika Vātarakta predominantly …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 Read article
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Uttarabasti in Female Infertility: A Retrospective Analysis of Clinical Outcomes and Safety Profile
Abstract: Background: Uttarabasti (UB) is a specialized Panchakarma procedure involving intrauterine instillation of medicated Sneha, classically indicated in Yonivyapad and Vandhyatwa. It facilitates targeted local drug delivery, bypassing gastrointestinal metabolism and enabling direct therapeutic action at the uterine level. In Ayurvedic understanding, UB achieves Garbhashaya Shuddhi and Apana Vata Anulomana — the two primary pathological corrections considered essential in Vandhyatwa. Infertility affects an estimated 10–15% of couples globally, with a substantial …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 2, 2026 Read article
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Autonomous Calibration of Medical Devices Using Synthetic Biosignals and Adaptive Learning
Abstract: The accuracy and reliability of modern biomedical diagnostic devices are critically dependent on effective calibration mechanisms capable of handling dynamic physiological and environmental variations. Conventional calibration approaches, which rely on static reference signals and manual adjustments, are inadequate in addressing challenges such as sensor drift, noise interference, motion artifacts, and long-term performance degradation. To overcome these limitations, this research proposes an innovative AI-driven adaptive biosignal simulation and calibration architecture for …
Published in Journal of Instrumentation Technology & Innovations · Vol. 16, Issue 2, 2026 Read article
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From Humours to Metabolism: An Integrative Review of Obesity Management in Unani Medicine
Abstract: Unani Medicine, a traditional complementary and alternative medicine (CAM) system, adopts a holistic, temperament-based approach to disease prevention and management. In classical Unani literature, obesity is described as Simān-e-Mufriṭ, a pathological condition arising from humoral imbalance, particularly the predominance of phlegm (Balgham) and derangement of temperament (Su’-e-Mizāj), most commonly of a cold and moist nature. This condition is attributed to a sedentary lifestyle, weakened digestive and metabolic faculties, and excessive …
Published in International Journal of Nutritions · Vol. 3, Issue 2, 2026 · pp. 10–25 Read article
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Muscle vs. Heart: A Comprehensive Review of Anabolic Steroid-Induced Cardiovascular Risks
Abstract: Anabolic-androgenic steroids (AAS) are widely used by athletes and bodybuilders to enhance muscle mass and performance. However, their misuse is associated with serious and often underrecognized cardiovascular risks. Despite their popularity, particularly among young adults, the long-term consequences of AAS abuse on cardiovascular health remain insufficiently explored in the literature. This review aims to: 1. Analyze the cardiovascular implications of AAS use. 2. Elucidate the molecular and physiological mechanisms contributing …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 2, 2026 Read article
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A Conceptual Framework for AI-Integrated Metabolomics in Predictive Health Systems for Resource-Constrained Environments
Abstract: The increasing prevalence of non-communicable diseases (NCDs) continues to place a significant strain on healthcare systems, particularly in low- and middle-income regions where access to early diagnostic infrastructure is limited. Conventional healthcare approaches remain largely reactive, often detecting diseases at advanced stages when treatment effectiveness is reduced. This challenge underscores the need for predictive, cost-effective, and data-driven healthcare solutions. This study presents a conceptual framework that integrates metabolomics with artificial …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 2, 2026 Read article
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Ashaya as Abode: Reconciling Ayurvedic Vata Theory with Intestinal Neurophysiology
Abstract: Background-Ashaya refers to a site or structure within the body where a substance resides. Ashaya refers to the internal sites or structures within the body where various substances reside Commonly, seven Ashayas are described in males, while in females there are eight, while Sharangadhara has described 9 Ashayas. Vatashaya denotes the specific site of Vata Dosha, which is considered the chief among the three Doshas due to its vital role …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 2, 2026 Read article
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Evaluation of Drug Utilization Patterns and Prescription Trends in Patients with Hypothyroidism and Hyperthyroidism in a Tertiary Care Hospital
Abstract: Background: Endocrine disorders affecting the thyroid gland represent some of the most frequently encountered conditions globally, necessitating prolonged therapeutic intervention and vigilant clinical surveillance. The evaluation of Drug utilization patterns (DUE) serves an essential function in examining prescriptive behaviours and promoting appropriate pharmaceutical management. Objective: To evaluate drug utilization patterns, prescribing trends, and rationality of therapy in patients with hypothyroidism and hyperthyroidism. Methods: A prospective, cross-sectional observational investigation was performed …
Published in Research and Reviews: A Journal of Medicine · Vol. 16, Issue 2, 2026 · pp. 1–5 Read article
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GenChrome-ML: A Machine Learning Framework for Early Detection of Chromosomal Disorders Using Genomic Data
Abstract: The increasing burden of chronic disease and cancer demands innovative, more rapid and effective diagnostic tools in the field of healthcare. The majority of current diagnostic tools are dependent upon clinical symptomology and manual evaluation, leading to delays in early detection and treatment. The development of artificial intelligence (AI) and machine learning (ML), in recent years, has offered opportunities for the enhancement of disease prediction, diagnosis and personalization of treatment …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 2, 2026 Read article
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Advanced Laser Technology for Curing Cancer Affected Melanoma-Cell
Abstract: In this paper we report the results about the study and experimental usage of a cancer curing laser equipment. Cancer can be detected using laser induced ultrasound .This device could scan a lymph node biopsy with laser pulses, whereby the pigment of melanin which is present in each and every cells reacts to the laser's beam, absorbing the light, and heating and cooling rapidly. This produces a popping sound that's …
Published in Journal of Electronic Design Technology · Vol. 3, Issue 1-3, 2012 · pp. 1–5 Read article
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Geotechnical and Geophysical investigations for a foundation underpinning solution in a residential building with differential settlements, in Asti Province (central Piedmont), NW Italy
Abstract: Foundation differential settlements are a recurrent topic for antique and no so antique buildings, for this particular case, an integrated approach of geotechnical and geophysical investigation was developed to provide information and support to the engineering design for the restoration of a building.Given the presence of widespread and pervasive wall fractures, compromising the static nature of the building, investigating the nature of the subsoil in depth was a need, in …
Published in Journal of Geotechnical Engineering · Vol. 10, Issue 3, 2023 · pp. 1–12 Read article
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Study of Ambu in Relation to Pathophysiology
Abstract: Water is most abundant in human body. It circulates all over the body and provides the medium and solute gets dissolved in it. Without water, there can be no existence of life and it acts as a volume conductor. In society, it seems to be considered as beneficial if taken in excess amount but not actually as beneficial as the society thinks in respect to obey the instruction of general …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 7, Issue 3, 2018 · pp. 11–15 Read article
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A Conceptual Study of Physiological and Clinical Significance of Nidra with Sleep
Abstract: Ayurveda is the science of life and its main aim is to maintain healthy status of healthy living being, i.e. prevention of disease and treatment of disease. In order to prevent the unmanifested diseases and to cure the manifested ones, an individual’s desire of happiness should follow the regimen prescribed in text of Ayurveda. As per Ayurvedic science, nidra is one among most essential factors responsible for a healthy life. …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 7, Issue 3, 2018 · pp. 6–10 Read article