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196 articles for “evidence based”
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Assessment of Finerenone Safety and Efficacy in Individuals with Type 2 Diabetes and Chronic Kidney Disease
Abstract: Background: In this work, we provide strong evidence for the safety and efficacy of finerenone in people with type 2 diabetes and chronic kidney disease. Our goal is to improve patients' quality of life and general well-being through our research. Aim: Finerenone exhibited a significant decrease in the likelihood of renal and cardiovascular (CV) events in individuals with both type 2 diabetes and chronic kidney disease. This exploratory subgroup analysis …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 06–09 Read article
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Raspberry Pi Based Tactical Autonomous Surveillance System
Abstract: In the ever-evolving realm of security and surveillance, the need for autonomous systems capable of operating in challenging environments has become increasingly evident. The Raspberry Pi-Based Tactical Autonomous Surveillance and Self-Destruction System addresses this need by combining advanced sensor technology, robust communication capabilities, and a self-destruction mechanism to provide a comprehensive security solution. This project proposes a Raspberry Pi-based tactical autonomous surveillance system that can be used to monitor and …
Published in Recent Trends in Electronics Communication Systems · Vol. 11, Issue 1, 2024 · pp. 1–7 Read article
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Prime Editing and Base Editing in Human Hematopoietic Stem Cells Toward Scarless Correction of Monogenic Blood Disorders
Abstract: Monogenic hematological disorders – such as sickle cell disease (SCD), β-thalassemia, and X-linked chronic granulomatous disease (X-CGD) – affect >400, 000 newborns worldwide each year, with a considerable burden in low-resource settings . Although donor-derived allogeneic hematopoietic stem-cell transplantation (HSCT) is widely regarded as curative, its application is limited due to issues of donor availability and graft-versus-host disease (GVHD) and conditioning-related toxicity. DSB-based conventional CRISPR-Cas9 strategies are limited by inefficient …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 1, 2026 Read article
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Contextualising health-disaster risk reduction pillars for under-resourced rural secondary schools in Limpopo Province, South Africa
Abstract: School communities in under-resourced rural settings face a disproportionate burden of health-related disasters, including outbreaks, water and sanitation failures, food insecurity and compound events that disrupt learning and wellbeing. Yet school based disaster risk reduction (DRR) evidence in Southern Africa is uneven with limited empirically guidance tailored to the organisational and infrastructural realities of disadvantaged schools. Drawing on the Comprehensive School Safety Framework and the World Health Organization's Health Emergency …
Published in International Journal of Education Sciences · Vol. 3, Issue 1, 2026 · pp. 124–135 Read article
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Integrating Advanced Technologies for the Scientific Revalidation of Ayurvedic Principles
Abstract: Background: Ayurveda, a 5,000-year-old holistic healthcare system, emphasizes the dynamic balance of body, mind, and spirit. Recent advancements in science and technology have accelerated its integration into global healthcare systems. Objective: This paper explores the contribution of modern tools and methodologies to the scientific validation and enhancement of Ayurvedic principles across education, clinical practice, and research. Methods: A comprehensive literature review was conducted using databases like PubMed, Google Scholar, and …
Published in Research and Reviews: A Journal of Medicine · Vol. 16, Issue 1, 2026 · pp. 1–6 Read article
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Fraud Detection in Government Procurement Using Machine Learning
Abstract: Fraud represents a significant challenge in the realm of procurement, with estimates indicating that between 12 and 30% of global procurement budgets are lost to fraudulent activities (OECD, 2023). The pervasive nature of procurement fraud, which may encompass a range of deceptive practices such as bid rigging, invoice fraud, and procurement kickbacks, not only undermines the integrity of financial operations but also results in substantial losses for organizations. These losses …
Published in Journal of Open Source Developments · Vol. 12, Issue 2, 2025 · pp. 19–34 Read article
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A Secure Storage Model with Authentication and Optimal Key Generation Based Encryption
Abstract: In digital forensics, ensuring the secure storage of digital evidence is crucial. This paper introduces a new method that uses advanced encryption and key generation techniques to protect digital evidence throughout an investigation. Cloud forensics, a modern approach to digital forensics, aims to safeguard evidence from online hacking. However, storing all evidence in one central location can reduce its reliability. To address this, we propose a digital forensics architecture for …
Published in Journal of Control & Instrumentation · Vol. 17, Issue 1, 2026 · pp. 7–13 Read article
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Formability analysis of steel and copper based alloy sheet by using Erichsen Cupping Test Machine
Abstract: Metallic material formability study is critical in a variety of industrial areas, including automotive, aerospace, and manufacturing. The present study aims to investigate the formability properties of steel and copper-based alloy sheets using the Erichsen cupping test machine, an established technique for evaluating sheet metal formability. The process involves manufacturing identical steel and copper-based alloy specimens and subjecting them to the Erichsen cupping test. The test determines the maximum deformation …
Published in Journal of Polymer & Composites · Vol. 11, Issue 12, 2023 · pp. 49–57 Read article
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Cementing Sustainability: Utilizing Waste Foundry Sand to Enhance Concrete Performance and Reduce Environmental Impact
Abstract: The incorporation of waste foundry sand into concrete production represents an environmentally conscious and cost-effective approach. This method involves substituting discarded foundry sand for a portion of traditional fine aggregates in concrete mixtures. The primary objective is to address environmental concerns associated with waste disposal while simultaneously achieving cost efficiency in construction materials. By integrating waste foundry sand into concrete, this practice promotes sustainability by reducing landfill waste and conserving …
Published in Journal of Construction Engineering, Technology & Management · Vol. 14, Issue 1, 2024 · pp. 13–21 Read article
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A Systematic Review on Coronary Heart Disease: A Transient Ischemic Stroke
Abstract: Coronary Heart Disease (CHD) and Transient Ischemic Attack (TIA) are significant cardiovascular and cerebrovascular disorders that often share similar risk factors and underlying pathophysiological processes. CHD involves the narrowing or obstruction of the coronary arteries due to atherosclerosis, resulting in diminished blood flow to the heart. A transient ischemic attack (TIA), often called a "mini stroke," occurs when blood flow to the brain is briefly disrupted, usually due to a …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 3, 2025 Read article
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Catalyst-Driven Degradation and Failure Analysis of Intergranular Cracking in 316H Studded Pipes under Refinery Heat Recovery Conditions
Abstract: A failure analysis investigation was carried out on a high-temperature studded pipe used in a convection module for heat recovery in an oil and gas refinery application after leakage was detected during pre-commissioning hydrotesting. The investigated pipe was manufactured from AISI 316H austenitic stainless steel, and carbon steel studs had been joined to its outer surface by high-frequency resistance welding. Two leaks were reported in the pipe under investigation, and …
Published in Journal of Catalyst & Catalysis · Vol. 13, Issue 1, 2026 Read article
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Evaluating the Usability and Effectiveness of Desktop Voice Assistants on Windows Operating Systems
Abstract: This paper presents an in-depth empirical study of usability and effectiveness regarding the use of desktop voice assistants in Windows operating systems. While a lot of research has been done on mobile-based assistants like Siri and Google Assistant, or smart speaker platforms like Amazon Alexa, desktop-based assistants remain comparatively under-explored. A total of 176 participants were surveyed to analyze their experiences with DVA in usability, multitasking, accuracy, accessibility, and overall …
Published in Journal of Operating Systems Development & Trends · Vol. 13, Issue 1, 2026 Read article
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Failure Analyte of Helicopter Wing: A Study
Abstract: Summarised issued form is description of different failure cases of winged propulsions. Ethic is basic study from usual aircraft powered through rotary wing i.e., helicopters. Rotor wing composes lift capability by spins; otherwise, accessed score is obtained from aerodynamic lift. Rotor spins about an axis so that etiquette is aligned either vertical or side-to-side. Advent of rotary wing aircraft are that used to be practice is to take off and …
Published in Journal of Mechatronics and Automation Read article
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Comparative Evaluation of Hibiscus Cannabinus and Solanum Trilobatum Extracts as Inhibitors for C- Steel Corrosion protection in Acidic Medium
Abstract: This study analyzed the efficacy of various inhibitors in safeguarding carbon steel against corrosion in hydrochloric acid. The compounds that were subjected to testing included Acalypha indica root extract (AIRE), Hibiscus cannabinus (HC), and Solanum trilobatum (ST) leaf extracts. The investigation focused on the inhibitory efficacy through the application of gravimetric and electrochemical impedance methods. GC-MS and FTIR were employed to investigate the features of the inhibitors and co-inhibitors. Tafel …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 555–565 Read article
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The Impact of Climate Change on Infectious Diseases: Potential Risks and Mitigation Strategies
Abstract: As we confront the pressing challenge of climate change, it's vital to recognize its intertwined connection with infectious diseases. We must now navigate a future that combines strong public health interventions, environmental stewardship, and strong policy actions as we stand at the crossroads of crises. In an attempt to lessen the drastic effects of climate change on the dynamics of disease transmission, this study identifies potential risks and creative solutions. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 21–32 Read article
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Plant-Derived Psychotropic Agents Targeting Neurotransmitter Systems: Pharmacognostic Evidence, Mechanisms, and Clinical Relevance
Abstract: Psychiatric health problems are also a large burden on global health and existing psychotropic drugs may be restricted by relative effectiveness, side effects, and inadequate long-term tolerability. Plant- based psychotropic agents have subsequently been the focus of interest in the form of complementary or alternative therapies. This review outlines the pharmacognostic, mechanisms of action and therapeutic importance of plant-based psychotropic agents against central neurotransmitter systems. The traditional medicinal practices give …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 · pp. 34–42 Read article
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Effect of Snehpana (Lipid Based Drug Delivery System) with Shatpala Ghrit in Non-Alcholic Fatty Liver Diseases
Abstract: Among all the Drug Delivery Systems, Snehpana (~Lipid Based Drug Delivery System) is being widely used because this facilitates uniform distribution and absorption of fat and water-soluble chemical constituents. Due to their effective size-dependent properties and challenges related to the solubility and bioavailability of water-soluble drugs, this system holds a significant advantage. Numerous studies have highlighted the potential of lipid-based formulations in managing chronic and life-threatening diseases. Shatpala ghrit (SG) …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 1, 2025 · pp. 1–11 Read article
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IoT Integration in Sustainable Agriculture
Abstract: The increasing demand for food production, environmental concerns, and resource limitations have necessitated the adoption of Internet of Things (IoT)-based innovative farming solutions. The current paper introduces an IoT-based system that integrates hydroponics, aquaponics, and poultry to promote sustainability, resource utilization, and agricultural productivity. Conventional farming practices are riddled with ineffective use of resources, uncertain environmental effects, and expensive operations. The new system facilitates real-time monitoring, automated decision support, and …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 14, Issue 2, 2025 · pp. 69–84 Read article
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Terminalia arjuna: The Medicinal Tree
Abstract: Over 85% of the medications used in both conventional and alternative medical systems come from plant sources. The stem bark of Terminalia arjuna (T. arjuna) is rich in minerals, flavonoids, and glycosides. T. arjuna bark is unique because flavonoids have been shown to have anti-inflammatory, lipid-lowering, and antioxidant properties, and glycosides are cardiotonic. A variety of topics related to its ethnomedical, phytochemical, pharmacological, and clinical significance to different medical conditions …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 3, 2025 · pp. 27–34 Read article
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AI-Based Criminal Identification System A Breakthrough Approach
Abstract: Identifying and locating a perpetrator is a time-consuming and difficult process. The perpetrators are growing more skilled, leaving no biological evidence or fingerprint impressions at the crime scene. Using cutting-edge face recognition technology is a quick and easy solution. Through the use of linear programming, this research presents an innovative approach to classifying all face tracks collectively. In addition to the following, it incorporates: a novel method for extracting more …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 2, Issue 1, 2024 · pp. 1–14 Read article