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154 articles for “Pharmacological Studies”
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An overview on the Medicinal Value of Leeches
Abstract: The present article highlights on the medicinal value of leeches. Leech belongs to phylum Annelida have played a significant role in ancient medicine for centuries, with their therapeutic and medicinal applications dating back to ancient human civilizations such as those of Egypt, Greece, and India. Historically, incidences shows it associated with blood letting, leeches were believed to restore balance to the body’s humors. In recent times, new experiments are being …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 15, Issue 1, 2026 · pp. 1–6 Read article
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Effect of Valsalva Maneuver Prior to Cannulation on Pain Among Patients Undergoing Peripheral Venous Cannulation
Abstract: Peripheral venous canulation is the common nursing procedure carried out which cause soreness to the recipient. Previous experience of peripheral venous cannulation may result in negligence or delay in need of medical care. Valsalva Maneuver is a non-pharmacological and cost- effective method to decrease intensity of pain during peripheral venous cannulation. Aim: To assess the effect of Valsalva Maneuver prior to cannulation on pain among patients undergoing peripheral venous cannulation. …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 2, 2024 · pp. 1–6 Read article
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Hakim Ismail Jurjani (1042–1137 AD): Life, Works, and Medical Legacy
Abstract: Hakim Ismail Jurjani, also known as Seyyed Isma’il Jorjani, was among the most distinguished physicians and scholars of medieval Persian medicine whose contributions significantly influenced the development of Greco-Arab and Unani medical traditions. His monumental encyclopedia, Zakhīra Khwārazmshāhī (Treasure of the Khwarazm Shah), is regarded as one of the greatest medical compilations of the Islamic Golden Age and represents a landmark in the evolution of Persian scientific literature. Unlike earlier …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 2, 2026 Read article
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Effectiveness of Habb-e-Suranjan and Roghan-e-Farfiyun in the Management of Waja-ul-Rukba (Knee Pain): A Review
Abstract: Introduction: Knee osteoarthritis is a painful condition that represents the degeneration of the cartilage and osteophyte formation in the knee joint, which affects millions of people worldwide. According to the Unani claimed text, accumulation of “madda” (substance) in joints, which is neither absorbed nor expelled, is due to the absence of Quawwat-e-Jazibah (power of absorption) and Quawwat-e-dafia (power of expulsion). Unani medicine presents a promising approach for managing knee osteoarthritis …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 2, 2025 · pp. 7–12 Read article
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Integrating Horticultural Techniques for the Propagation of Ethnomedicinal Pteridophytes in the Himalayan Region
Abstract: The Doon Valley, including the regions of Dehradun, Mussoorie, and Chakrata in Uttarakhand, India, is rich in ecological and medicinal plant diversity. This study focuses on the geographical distribution, habitats, and medicinal applications of 28 pteridophyte species found in these regions. Detailed field observations and data collection from various scientific journals, databases, and publications have contributed to understanding the traditional and pharmacological uses of these plants. The results show that …
Published in International Journal of Trends in Horticulture · Vol. 1, Issue 2, 2024 · pp. 1–19 Read article
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Herbal Medicines and Complementary Therapies: Their Role, Types and Applications
Abstract: Medicinal plants are used in herbal medicine to treat and prevent illnesses. This includes the use of standardized and titrated botanical extracts in addition to common and traditional medicines from different cultures. The safety of a treatment may be suggested by its long history and deep cultural roots in traditional medical systems, but this does not always imply that it is effective. This is especially important in herbal medicine, since …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 40–53 Read article
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CB₁ Reverse Agonists: A Cheminformatic and Patent Landscape Study
Abstract: The endocannabinoid system plays a crucial role in numerous physiological functions, making cannabinoid receptor 1 (CB1) an attractive target for therapeutic development. This review provides a systematic analysis of patent filings from 2019 to 2023 that focus on small-molecule CB1 reverse agonists. It begins with an overview of the endocannabinoid system, highlighting CB1’s involvement in energy balance, pain regulation, and neuroinflammatory processes The main section of the review examines fifteen …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 33–36 Read article
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Synthesis and Characterization of Polymer-Based Benzamide Derivatives with Potential Biomedical Applications
Abstract: The present study explores the synthesis and characterization of polymer-supported benzamide derivatives, focusing on their potential biomedical applications. The use of polymer-supported synthesis offers several advantages, including improved reaction efficiency, ease of purification, and reusability of the support material, making it an environmentally friendly and cost-effective approach. The synthesis involved a stepwise reaction sequence, with polymeric supports facilitating controlled functionalization and ensuring high product purity. These materials have been widely …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 Read article
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The Clinical Landscape of Wogonin: Advancing Targeted Treatments for Chronic Diseases
Abstract: The traditional Chinese medicinal herb Scutellaria baicalensis Georgi, commonly known as Chinese skullcap or Huang-Qin, has long been used to treat a variety of conditions, including cancer, viral infections, and seizures. Its pharmacological effects are largely attributed to the high concentration of flavones, particularly wogonoside, and its aglycone derivative, wogonin. Among the bioactive compounds found in S. baicalensis, wogonin has garnered the most scientific attention due to its potent therapeutic …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 46–52 Read article
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Acupuncture in Pain Management: A Neurophysiological and Clinical Perspective
Abstract: Acupuncture, a key component of traditional Chinese medicine, has gained widespread recognition as an alternative therapy for pain management. This practice involves the insertion of fine needles into specific points on the body to influence the flow of energy or "Qi" (pronounced "chee") and restore balance. Mechanistically, acupuncture is believed to modulate pain through neurophysiological pathways, including the release of endorphins, the activation of the body's natural analgesic systems, and …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 Read article
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Hydro-alcoholic Extract of Herbal Formulation and Evaluation of Papaya leaf And Orange Peel for treatment of Dengue Fever
Abstract: The fastest-spreading viral disease in the world is dengue contamination, which is spread by mosquitoes. Carica papaya leaf juice aids in raising the platelet count, and it occurs primarily in tropical and subtropical countries. The primary goal of this study is to inform medical experts about the use of Carica papaya leaf extract formulations (SYRUP) to treat dengue fever, a potentially fatal illness. Approach: To cure this illness, a water …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 23–33 Read article
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Needles of Wellness: Exploring the Transformative Benefits of Acupuncture
Abstract: Acupuncture, rooted in traditional Chinese medicine, has expanded beyond treating physical pain to playing a significant role in mental wellness. The term “Needles of Wellness” captures its dual benefits in pain relief and emotional health. While effective for conditions, like osteoarthritis and migraines, recent studies show its growing use in managing anxiety, depression, insomnia, and PTSD. Stimulating specific body points modulates the autonomic nervous system, reducing cortisol and enhancing endorphin …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 2, 2025 · pp. 1–9 Read article
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Scientific Appraisal of Unani Drugs Used in Neurological Disorders
Abstract: Background: Neurological disorders are prevalent and are increasing. The Unani system of medicine provides insights into the pathogenesis, prevention, and treatment of these diseases. Objective: This study explores the Unani perspective on neurological disorders, focusing on therapies and the pharmacodynamics of related medicines. Methods: A comprehensive review of Unani literature was conducted using digital and traditional sources. Unani texts, like “Al Qanoon Fil Tib” by Ibn Sina and “Al Jami …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2026 · pp. 34–44 Read article
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Stilbenes: A Molecular Docking and ADMET Analysis Approach on an Emerging Resource for Scavenging Reactive Oxygen Species in the Field of Colon Malignancy
Abstract: Objective: Colon malignancy, also referred to as colon cancer, originates as precancerous polyps in the colon or rectum, which have the potential to thrive and progress into cancerous tumors over time. This study delves into various bioactive compounds (from natural sources like plants) to assess their potential efficacy in inhibiting colon malignancy as compared to conventional methods. Methods: The objective of this study was to employ computational methodologies to evaluate …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 3, 2024 · pp. 29–38 Read article
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A Comprehensive Review on Mentha arvensis Species
Abstract: Mentha arvensis L., often referred to as field mint or wild mint, is a fragrant medicinal herb in the Lamiaceae family and is extensively found in temperate and subtropical areas. The plant is appreciated for its essential oil, notably high in menthol, which adds to its unique scent and extensive medicinal possibilities. Historically, M. arvensis has been utilized in several medical systems for addressing digestive issues, respiratory problems, headaches, and …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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A Factualistic Study of Phytomedicinal Activity of Curcuma longa (Haldi): Plant That Infuses Life
Abstract: Curcuma longa, commonly known as turmeric, is a plant of remarkable medicinal significance that has been utilized for centuries in traditional medicine and has garnered considerable attention in modern scientific research. This review explores its extensive phytomedicinal potential, focusing on the plant's bioactive compounds, particularly curcumin, which is recognized as the primary agent responsible for its therapeutic properties. Turmeric contains an array of chemical constituents, including curcuminoids, volatile oils, and …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 14–24 Read article
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Computational Investigation of Withania somnifera Compounds Targeting S. pombe SMN YG-Dimer in Spinal Muscular Atrophy: Insights from Molecular Docking Analysis
Abstract: Objectives: The primary objective of this study is to determine the potential of phytochemical constituents of Withania somnifera in treating spinal muscular atrophy, an autosomal recessive genetic neurodegenerative disorder, through computational techniques. To investigate the binding affinity of phytocompound to the target protein S. pombe SMN YG-Dimer through molecular docking. Besides, evaluating the pharmacological attributes of phytochemical constituents to assess their ability as an ideal prospect for developing therapeutic medication. …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 2, 2024 · pp. 39–52 Read article
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A Review on Kaempferol Eye Drops for the Glaucoma Treatment
Abstract: One of the main causes of permanent blindness, glaucoma is defined by gradual damage to the optic nerve, mostly brought on by oxidative stress, neuroinflammation, and high intraocular pressure (IOP). The investigation of herbal alternatives is necessary since current synthetic therapies, such as beta-blockers and prostaglandin analogs, frequently result in ocular discomfort, systemic toxicity, and poor patient compliance. Clitoria ternatea contains kaempferol, a bioactive flavonoid that has shown anti-inflammatory, antioxidant, …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 110–121 Read article
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Computational Exploration of Bhrijraj-derived Phytochemicals as Potential Anti-inflammatory Agents: A Molecular Docking Study with Cyclooxygenase-II Complex
Abstract: The molecular docking analysis was meticulously conducted using state-of-the-art computational tools, notably Chimera and Python. These tools were employed to unravel the complex interactions between the identified phytochemicals from Bhrijraj and the target protein, COX-II. The 3D structures of the phytochemicals were prepared with precision using ChemSketch, ensuring accuracy in the subsequent molecular docking simulations. This rigorous approach enhances the reliability and validity of the findings. This research aims to …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 31–37 Read article
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In silico Molecular Docking Analysis of Stephania glabra phytocompounds Targeting Thymidylate Kinase for potential Antituberculosis Activity
Abstract: Tuberculosis (TB) is an infectious disease caused by the bacteria Mycobacterium tuberculosis. It mainly affects the lungs and spreads through the air when a person with active TB in their lungs coughs, sneezes, or spits. This study investigates several bioactive compounds derived from plants to forecast how effective plant-based ligands will be at preventing tuberculosis. The purpose of the study was to use computational techniques to assess the effectiveness of …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article