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154 articles for “PKA/CREB pathway”
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Intergenerational Trauma and Cultural Resilience: Exploring the Impact of Family Norms on Mental Health Disclosure
Abstract: This comprehensive review examines how intergenerational trauma and cultural resilience influence individuals' choices to disclose or conceal their mental health challenges in family contexts. This paper utilizes 50 peer-reviewed studies out of 80 in total from various cultural contexts, this paper explores how family norms, especially in collectivist cultures, impact the disclosure of mental health issues. This review paper uses a thematic analysis strategy, systematically integrating qualitative, quantitative, and mixed-method …
Published in International Journal of Behavioral Sciences · Vol. 2, Issue 2, 2025 · pp. 53–58 Read article
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Nutraceuticals Unveiled: Exploring the Science, Benefits, and Future of Functional Food
Abstract: The rapidly developing subject of nutraceuticals is critically examined in this review, with a focus on its scientific basis, proven health advantages, and possible future applications in the functional food industry. Key bioactive ingredients that contribute to the therapeutics effectiveness of functional foods, including flavonoids, polyphenols, carotenoids, probiotics, and essential fatty acids, have been identified and characterized as a result of recent developments in nutritional science. Both experimental and clinical …
Published in International Journal of Nutritions · Vol. 2, Issue 2, 2025 Read article
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Advancing Cancer Vaccine Development through CRISPR/Cas9 Technologies and Future Opportunities
Abstract: The advent of CRISPR/Cas9 genome editing has revolutionized the cancer immunotherapy market, offering unprecedented precision and versatility in the development of next-generation cancer vaccines. This review examines how CRISPR technologies are being integrated into various stages of cancer vaccine development including neoantigen discovery, dendritic cell engineering, cancer cell reprogramming, and tumor microenvironment modulation. In the area of neoantigen discovery, CRISPR enables rapid identification and validation of tumor-specific mutations, thereby supporting …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 Read article
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Multifunctional Materials for Electro-Mechanical Applications: Synergistic Integration of Strength and Conductivity
Abstract: The integration of mechanical strength and electrical conductivity within a single material system has emerged as a critical requirement in the development of next-generation multifunctional materials. These materials are increasingly sought after in fields such as aerospace, flexible electronics, energy storage, and structural health monitoring, where the traditional separation of structural and functional materials leads to inefficiencies in weight, space, and overall performance. The convergence of these properties enables compact …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 3, Issue 1, 2025 · pp. 1–6 Read article
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Ecological, Economic, and Medical Roles of Fungi: Insights from Mycology in Addressing Global Challenges"
Abstract: The large and diverse kingdom of fungi is vital to ecosystems, industry, agriculture, and medicine. Due to its ecological and biotechnological value, mycology has grown in importance. Fungi are crucial to natural systems and human life, decomposing organic materials, developing mutualistic interactions with plants, and producing antibiotics and fermented products. Recent advancements in molecular biology and genomics have significantly enhanced our understanding of fungal diversity, physiology, and evolutionary processes. These …
Published in International Journal of Fungi · Vol. 2, Issue 2, 2025 Read article
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Magnetic and Radioactive Nanoparticles for Improved Theranostics and AI Assisted Radiation Therapy
Abstract: Nanoparticles based therapeutic and theranostics technique is becoming an active area of research in nanomedicine. The sensitivity, biocompatibility, and stability of magnetic and radioactive nanoparticles determine their functionality. This research highlights the impacts of magnetic and radioactive nanoparticles on therapeutic techniques namely, cell therapy, gene therapy, and tissue regeneration. Then, it is intended to brief a principal role of these therapeutic techniques to envisage theranostics medicine and radiation therapy using …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 2, 2025 · pp. 10–21 Read article
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A Review on Unmasking Merkel Cell Polyomavirus: From Discovery to Cancer Driver
Abstract: Merkel cell polyomavirus (MCPyV) is a small, non-enveloped, circular double-stranded DNA virus belonging to the Polyomaviridae family, first characterized in 2008. Epidemiological data suggest widespread exposure, with seroprevalence rates approaching 80% in adults. While primary infection is typically asymptomatic, rare integration events in Merkel cells can initiate oncogenesis, yielding Merkel cell carcinoma (MCC), a neuroendocrine skin cancer with a five-year survival rate under 60%. This review integrates findings from six …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 6–11 Read article
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Exploring Abies grandis phytocompounds potential by in silico analysis targeting on the 5P9J Protein
Abstract: Blood Cancer, also popular with name ‘Hematologic cancer’ have variety of types: Leukaemia, Lymphoma, Myeloma, uncontrolled multiplication of blood cells mainly affecting to bone marrow and blood cells (White Blood Cells). Lymphoma, originating from lymphatic system resulted in uncontrolled growth and instead of normal apoptosis development of tumor. Myeloma, uncontrolled formation of malignant plasma cells leads disrupting production of healthy blood cells. This situation creates variety of diseases like anaemia, …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article
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Gene Editing in Dairy Cows: Advancing Milk Yield, Health, and Resilience for Sustainable Dairy Development
Abstract: Gene editing has emerged as a transformative tool in dairy science, offering unprecedented opportunities to enhance productivity, improve animal health, and bolster resilience against environmental challenges. This study explores the potential of gene editing technologies, including CRISPR-Cas9, in advancing milk yield, optimizing milk composition, and addressing genetic disorders in dairy cows. Specific applications include targeting genes associated with mastitis resistance, improving feed efficiency, and introducing heat tolerance traits to adapt …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 Read article
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Samelisant, an H3 Receptor Agonist as an Anti-Alzheimer Potential – A Pilot Study on Molecular Docking
Abstract: Neurodegenerative diseases have become more prevalent and about 55 million of the population are affected by dementia globally. One of the most important neurodegenerative diseases is Alzheimer’s disease which is known for its effect on memory and cognitive impairment. Alzheimer’s disease (AD) is an area of intense scientific investigation due to its high prevalence and the lack of a definitive cure. Amyloid precursor protein plays a central role in Alzheimer’s …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 · pp. 15–26 Read article
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Integrating Digital Twins, Smart Materials, and Human Machine Collaboration for Sustainable Smart Manufacturing: Smart CNC & Industry 4.0 Applications
Abstract: The rapid evolution of Industry 4.0 and the emerging transition toward Industry 5.0 have been catalyzed by the convergence of intelligent digital technologies such as digital twins, cyber–physical systems (CPS), artificial intelligence (AI), the Internet of Things (IoT), and human-in-the-loop (HITL) frameworks. These technologies have transformed traditional manufacturing into adaptive, data-centric ecosystems capable of real-time optimization and predictive decision-making. In recent years, the fusion of computer numerical control (CNC) machines, …
Published in International Journal of Manufacturing and Production Engineering · Vol. 3, Issue 2, 2025 · pp. 1–8 Read article
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Host Invasion to Immune Evasion: Emerging Concepts in Pathogen Virulence Strategies
Abstract: Pathogens have evolved a wide repertoire of virulence strategies that allow them to invade host tissues, establish infection, and circumvent immune responses. From the initial steps of adhesion and colonization to complex molecular mimicry, antigenic variation, and immunomodulation, pathogens display remarkable adaptability. While traditional research has emphasized host cell entry and toxin production, emerging evidence highlights subtler and more dynamic strategies such as manipulation of host signaling pathways, subversion of …
Published in International Journal of Pathogens · Vol. 2, Issue 2, 2025 Read article
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Sustainable Membrane Technologies for Environmental and Industrial Applications: A Review
Abstract: Membrane-based technologies have become indispensable in addressing global environmental and industrial challenges, including water scarcity, pollution control, and energy efficiency. While conventional membranes provide high selectivity and process efficiency, their sustainability is limited by factors such as fouling, high energy consumption, and end-of-life waste management. Recent advances in material science, nanotechnology, and bio-inspired design have led to the emergence of sustainable membranes with improved durability, lower environmental footprint, and broader …
Published in International Journal of Membranes · Vol. 2, Issue 2, 2025 · pp. 7–12 Read article
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Integrated, Geospatial Risk Assessment of Air, Water, and Soil Pollution Impacts on Agricultural Sustainability using Advanced Digital Technologies
Abstract: The systemic threat posed by the convergence of air, water, and soil contaminants represents a critical challenge to global agricultural resilience and food security. Traditional, site-specific pollutant monitoring methods are insufficient for capturing the dynamic, diffuse, and often nonlinear nature of environmental risk pathways that permeate agrarian landscapes. This study presents a robust framework for comprehensive risk assessment utilizing a synergistic suite of modern tools designed for spatial, temporal, and …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 3, Issue 2, 2025 · pp. 28–37 Read article
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Climate Change and Air Pollution Dynamics: Synergistic Effects and Mitigation Strategies
Abstract: Climate change and air pollution are deeply interlinked environmental problems that jointly exacerbate human health, ecosystem integrity, and economic well‑being. As global temperatures rise, shifts in meteorological conditions—such as increased heat, altered precipitation, and more frequent extreme weather events—modify pollutant generation, dispersion, chemical transformation, and removal processes. Meanwhile, many sources of air pollution are also sources of greenhouse gases (GHGs), giving rise to potential co‑benefits or trade‑offs when formulating mitigation …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 3, Issue 2, 2025 · pp. 38–42 Read article
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Thermodynamic Optimization and Exergy-Based Performance Analysis of Hybrid Thermal Management Systems for Electric Vehicles
Abstract: The transition toward sustainable transportation has brought electric vehicles (EVs) to the forefront of modern engineering innovation. Despite their environmental benefits and improved energy efficiency, EVs face major thermal challenges that affect performance, safety, and durability. Efficient thermal management of batteries, power electronics, and electric drive systems is vital to ensure reliability under diverse operating conditions. This study presents a detailed thermodynamic optimization and exergy-based performance analysis of hybrid thermal …
Published in International Journal of Energy and Thermal Applications · Vol. 3, Issue 2, 2025 · pp. 19–23 Read article
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Integrating Biotechnology, Physiology, and Agroecological Practices for Sustainable Crop Production and Protection
Abstract: Global agriculture is currently confronting a wide range of complex challenges, including a rapidly growing population, climate change, increasing pest and disease pressures, soil degradation, water scarcity, and the urgent need for sustainable intensification of crop production. Addressing these issues requires integrated strategies that combine crop improvement (through modern breeding and biotechnology), precision agronomic practices related to soil, irrigation, and nutrition, as well as advancements in plant physiology, molecular biology, …
Published in International Journal of Trends in Horticulture · Vol. 2, Issue 2, 2025 · pp. 1–6 Read article
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Histological Effects of the Antibiotic Gentamicin on the Ovarian Tissue of Female White Laboratory Rats
Abstract: This study aimed to evaluate the histological alterations induced by Gentamicin in the ovarian tissue of white laboratory rats. A total of 12 adult female rats were used and randomly divided into two groups, with each group consisting of six animals. The experimental group received Gentamicin at a dose of 120 mg/kg body weight administered as an injection once daily, while the control group received an equivalent volume of normal …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 1–8 Read article
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Photoreceptor Dynamics: Light Sensing and Cellular Responses for Photochemistry
Abstract: Photoreceptor dynamics represent a fundamental aspect of photochemistry, encompassing the mechanisms by which biological systems detect and respond to light stimuli. Photoreceptors are specialized proteins that undergo structural and functional changes upon photon absorption, initiating a cascade of molecular events that translate light signals into cellular responses. These proteins are ubiquitous across life forms, including microbial rhodopsins, plant phytochromes, and animal opsins, each finely tuned to specific wavelengths and light …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 3, Issue 2, 2025 · pp. 28–32 Read article
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Future Challenges of Photocatalytic Water Splitting: Sustainability
Abstract: Photocatalytic water splitting has emerged as a promising technology for sustainable hydrogen production through the direct utilization of solar energy. This process mimics natural photosynthesis, using semiconductor materials to absorb light and drive the decomposition of water into hydrogen and oxygen. The method provides a sustainable and eco-friendly solution to the global energy challenge by enabling the reduction of carbon emissions. Among various solar-to-chemical energy conversion approaches, photocatalytic water splitting …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 3, Issue 2, 2025 · pp. 43–48 Read article