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296 articles for “Clinical Practice”
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Epigenetic Modifications in Health, Disease, and Precision Therapeutics (From Genome to Epigenome)
Abstract: Introduction: Epigenetic alterations play a crucial role in regulating gene expression in both normal physiological and disease states. These reversible modifications—such as DNA methylation, histone acetylation, phosphorylation, ubiquitination, and chromatin remodelling—are increasingly implicated in complex diseases including cancer and neurodegenerative disorders. Despite advances in standard therapeutic approaches, patient responses remain variable, largely due to genetic heterogeneity and epigenetic dysregulation. This highlights the need for incorporating epigenetic understanding into personalized medicine. …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 Read article
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Dental and Oral Health Challenges in Patients with Eating Disorders: An Updated Review
Abstract: Eating disorders are complicated psychiatric disorders with profound systemic and oral health implications that are often not identified in clinical practice. Dietary restriction, binge eating, and self-induced vomiting are disorders eating behavior that negatively impact the oral cavity via nutritional deficiency, exposure to acid, malfunction of salivary activities, and changes in immune and microbial. These processes lead to a wide spectrum of oral and dental effects such as dental erosion, …
Published in Research and Reviews: A Journal of Dentistry · Vol. 17, Issue 1, 2026 · pp. 25–34 Read article
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Impact of Hypoxia on Cardiopulmonary Adaptation in Canines: A Comprehensive Review
Abstract: Hypoxia triggers a series of cardiopulmonary responses that play an important role in oxygen delivery and the continuation of physiological activity in mammals. Canines are also a useful translational model of study to examine these adaptive responses because of their anatomical, physiological, and cardiopulmonary differences with humans. This review summarizes the experimental data of acute, subacute and chronic hypoxia in dogs with particular focus on the variations in cardiac functioning, …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 15, Issue 1, 2026 · pp. 13–24 Read article
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Clinical metabolomics: Useful insights, perspectives, and challenges.
Abstract: Metabolomics provides a comprehensive snapshot of smallmolecule intermediates and end products of cellular processes and thereby links genotype, environment, and phenotype in human disease . Over the last decade, advances in liquid chromatography–mass spectrometry (LC–MS) and nuclear magnetic resonance (NMR) spectroscopy have enabled high-throughput profiling of thousands of metabolites from microliter volumes of clinical samples . Clinical metabolomics is now emerging as a tool for disease diagnosis, risk prediction, therapeutic …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 29–37 Read article
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Exploring the Intersection of AI Network Pharmacology and Ayurveda: Innovations in Traditional Medicine
Abstract: Integrative frameworks that integrate traditional medicine and modern computer research are increasingly important for advancing evidence-based, individualized healthcare. One interesting strategy is the combination of Ayurveda, network pharmacology, and artificial intelligence (AI). AI expands the capability by allowing for the quick analysis of biomedical big data, the identification of therapeutic trends, and the optimization of treatment plans. Ayurveda, with its long-standing emphasis on individualized care, holistic balance, and natural remedies, …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 3, 2025 · pp. 92–98 Read article
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Integrating Advanced Technologies for the Scientific Revalidation of Ayurvedic Principles
Abstract: Background: Ayurveda, a 5,000-year-old holistic healthcare system, emphasizes the dynamic balance of body, mind, and spirit. Recent advancements in science and technology have accelerated its integration into global healthcare systems. Objective: This paper explores the contribution of modern tools and methodologies to the scientific validation and enhancement of Ayurvedic principles across education, clinical practice, and research. Methods: A comprehensive literature review was conducted using databases like PubMed, Google Scholar, and …
Published in Research and Reviews: A Journal of Medicine · Vol. 16, Issue 1, 2026 · pp. 1–6 Read article
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The Global and Regional Challenge of Pan-Antibiotic Resistance: A Review of Emerging Threats and Mechanisms
Abstract: Antimicrobial resistance (AMR) is one of the major and most intricate threats to the health of the 21st century as it is core to the undermined expertise of the common clinical practice and public health security worldwide. The problem is characterized by the extensive development of bacterial pathogens into extremely drug-resistant (XDR) and pan-drug-resistant (PDR) so- called superbugs faster than it can be done with therapeutics. It is a synthesis …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 · pp. 28–37 Read article
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A Systematic Review of the Herbal Medicinal Plants With Anti-Obesity Potential
Abstract: Obesity is a chronic, multifactorial metabolic condition characterized by abnormal fat accumulation. It is mainly driven by the intricate influence of genetic, environmental, hormonal, metabolic and lifestyle determinants. The burden of obesity has risen considerably over the past few years, making it one of the major health concerns in both developed and developing countries alike. The rapid increase globally in obesity prevalence is linked with numerous health complications such as …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 2, 2026 · pp. 31–38 Read article
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Nanoparticles in Cutting-edge Healthcare: Current Use and Emerging Issues
Abstract: Nanoparticles are sub-micron-sized particles (less than 100 nm on average). Using these materials as contrast agents in imaging and as carriers for medication and gene transfer into malignancies has given them a prominent place in contemporary medicine. Nanoparticles allow for previously inconceivable levels of analysis and therapy. However, nanoparticles provide new societal and environmental challenges, especially regarding toxicity. In this overview, we discuss how nanoparticles have benefited contemporary medicine and …
Published in Journal of Polymer & Composites · Vol. 11, Issue 3, 2023 · pp. 105–118 Read article
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Acne Vulgaris in Unani (Greco Arabic) and Modern Perspectives: Pathophysiology, Diagnosis and Clinical Management
Abstract: AbstractAcne is a worldwide distressing dermatological disorder affecting millions of adolescents every day without any racial predilection. It is prevalent in 90% of adolescents. The objectives of this review are to summarize the concept of acne and its management in conventional and Unani system of medicine and to place it in the perspective with current clinical practice. This review article is based upon the literature in Unani (Greco-Arabic) texts regarding …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 2, Issue 3, 2013 · pp. 11–19 Read article
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A Study to Assess the Level of Stress among Nursing Students in Selected Nursing Institutions of Karnataka, India
Abstract: Stress has been identified as a 21st century disease and has been viewed as a complex and dynamic transaction between individuals and their environments. Academic stress among college students has been a topic of interest for many years. There is little empirical evidence about the level of stress suffered by nursing students and its impact on their health throughout clinical practice. Therefore, a study has undertaken to explore the level …
Published in Journal of Nursing Science & Practice · Vol. 8, Issue 2, 2018 · pp. 1–5 Read article
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A Future Revolution in Medical/Dental Therapeutics: Medical Marijuana
Abstract: Dispensing and use of marijuana (Cannabis) and derivatives are restricted under federal statutory control in the United States as “SCHEDULE 1” substances (illegal drugs). However, at the state level (September 2016), “medical marijuana” is legal in 20 states plus “recreational marijuana” in four states and the districts of Columbia. Several other states have litigation for marijuana decriminalization on the November 2016 ballot. Pharmacotherapeutic use of marijuana and its derivatives may …
Published in Research and Reviews: A Journal of Dentistry · Vol. 7, Issue 3, 2016 · pp. 1–6 Read article
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Antioxidants in Dentistry: Clinical Significance and Controversies
Abstract: Antioxidants are extensively used in routine general clinical practice in the present era. Oxidative stress plays an important role in the etiology of various oral lesions. Increased incidence of oral cancer and potentially malignant disorders, where the oral environment is damaged by the production of free radicals warrants the need for research and evidence in the use of antioxidants in the field of dentistry. Keywords: Antioxidants, free radicals, oxidative stress
Published in Research and Reviews: A Journal of Dentistry · Vol. 4, Issue 3, 2013 · pp. 1–5 Read article
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Perception of Medical Students about Electronic Discharge Summaries
Abstract: On the increase is the utilization of electronic discharge summaries (EDS) for clinical perspective as well as for research; but rarely studies have been made in recent years which look at the perspectives of medical students regarding usage of EDS. Medical students are a critical stakeholder in the hospital operations and they can provide useful analysis on everyday processes that impact patient care throughout the process of discharge summary. The …
Published in Research and Reviews: A Journal of Health Professions · Vol. 2, Issue 3, 2012 · pp. 18–29 Read article
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An Experimental Pathological Study on the Prophylactic Effect of N-acetylcysteine on Alopecia from Anti-cancer Drugs
Abstract: Prevention of alopecia from anti-cancer drug, Cyclophosphamide, is important for improving quality of life in patients with cancer. Empirically, when Cyclophosphamide (150 mg/kg) infused to rats subcutaneously and intraperitoneally, severe alopecia developed in rats infused intraperitoneally. Moreover, rats infused both of N-acetylcysteine and Cyclophosphamide showed less skin vasculature and scaring of hair follicle, larger caliber of hair follicle and hair, thicker medullary and cortical layers and epimysium, and denser hair …
Published in Research and Reviews: A Journal of Medicine · Vol. 13, Issue 1, 2023 · pp. 21–27 Read article
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Music Based Remediation Therapy as an Adjunct to Conventional Physiotherapy Treatment for Primary and Secondary Impairments in Patients with Traumatic Brain Injury and Stroke: A Systematic Review
Abstract: Stroke is a second leading cause of death and major cause of long term disability whereas traumatic brain injury being a disabling health condition. Music therapy is a therapeutic application of music to cognitive, behaviour, sensory and motor dysfunction. To examine the effects of music therapy as an adjunct intervention with conventional treatment versus conventional treatment alone and other therapies on cognition, behaviour, upper extremity function, fine motor skills and …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 6, Issue 1, 2016 · pp. 1–9 Read article
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Use of Computer Optimal Interpolation for Prognosis of Metastases Appearance Timing and Estimation of the Results of Treatment of Malignant New Formations
Abstract: The prognosis of metastases appearance timing and estimation of the results of treatment of the malignant new formations is a very important and vital problem of clinical oncology. Improvement of the existing methods of estimation of metastases appearance timing and of the results of malignant new formations treatment is important for development of new methods of metastases prevention and for the effective estimation of the results of treatment. In this …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 8, Issue 3, 2019 · pp. 1–8 Read article
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A Comparative Study of Lodhrasevyadi Yoga with Neelithulasyadi Yoga in Lootha Visha (Spider Poison)
Abstract: The poison of loothas or spiders comes under Jangama Visha. Loothas can exert their venom through various body principles as per Ayurvedic concept. They are able to produce both general and dermatological signs and symptoms. The reason for the selection of lootha visha as the topic for this work is that spider poisoning is very common in the clinical practice of Agadatantra. According to general statistical information at outpatient level …
Published in Research and Reviews: A Journal of Toxicology · Vol. 12, Issue 1, 2022 · pp. 9–20 Read article
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Shiqaq-e-Maqad (Fissure in Ano) As Per Unani System of Medicine
Abstract: Anal fissure is one of the most common anorectal condition encountered in clinical practice. It is a longitudinal split in the anoderm, with surrounding oedema and inflammatory induration which causes painful defecation, bleeding with streaks of blood on the surface of stool or on toilet paper and itching per rectum. As per Modern aspect, the aetiology of anal fissure is not known. They generally arise with local trauma caused by …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 7, Issue 2, 2020 · pp. 28–33 Read article
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Anticancer, Bioactive, & Therapeutic Applications of Cannabinoids
Abstract: Cannabinoids, a complex class of lipophilic compounds found in Cannabis sativa L., are attracting significant clinical interest for their multifaceted therapeutic potential, particularly within oncology. This review provides a comprehensive synthesis of contemporary knowledge detailing the distinct anti-cancer properties of phytocannabinoids (such as δ-tetrahydrocannabinol and cannabidiol), endogenous endocannabinoids, and synthetic analogues. Accumulating evidence from robust in vitro and in vivo oncological models demonstrates that these compounds aggressively suppress tumor progression …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 2, 2026 · pp. 17–30 Read article