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118 articles for “Bio-medical innovation”
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The Art of Drug Design and Process Chemistry
Abstract: The creation of safe and efficient medications depends heavily on the art of drug design and process chemistry. This multidisciplinary discipline designs and optimizes drug candidates for therapeutic uses by fusing the concepts of biology, chemistry, and engineering. Researchers can develop compounds with pharmacological activity by using logical drug design techniques if they have a thorough understanding of the molecular targets implicated in disease pathways. By making it easier to …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 1–10 Read article
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Variations of Macroplastics in Water and Sediments at Bundu Waterfront, Upper Bonny Estuary, Rivers State, Nigeria
Abstract: Macroplastic pollution has become an increasingly severe environmental challenge, particularly in urban waterfronts where waste management is inadequate. Bundu Waterfront of the Upper Bonny Estuary in Port Harcourt, Rivers State is a sink for macroplatics from careless disposal of solid wastes and inadequate management thus affecting the biological integrity and aquatic life of this estuary. The resultant impact of the macroplastics on abiotic factors through the evaluation of different floating …
Published in Journal of Water Pollution & Purification Research · Vol. 13, Issue 2, 2026 · pp. 12–22 Read article
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Exploring Carbon Nanotubes in Nanotechnology: Functional Properties, Surface Modifications, and Biomedical Innovations
Abstract: Significant progress has been made in nanotechnology in recent years, especially in the creation of sensors with a broad range of uses. Among these, carbon nanotubes (CNTs) are cylindrical structures composed of carbon, with diameters in the nanometer range. CNTs originate from graphite sheets, where the graphite layers resemble a rolled-up, continuous, and robust hexagonal mesh. These hexagons have carbon atoms at their vertices. The fabrication of CNTs typically involves …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 2, Issue 2, 2024 · pp. 24–31 Read article
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Liposomes Innovative Role as a Drug Delivery System: A Detailed Analysis
Abstract: The first nanomedicine to be approved for use in clinical settings was liposomes. These are the spherical vesicles with a bilayer of phospholipids enclosing a middle empty aqueous region. Because of their extraordinary potential to stop medication deterioration and lessen unwanted effects, liposomes are being utilized more and more for targeted drug distribution. For targeted drug delivery, the pharmaceuticals can be integrated into the liposomes' aqueous space or phospholipid bilayer. …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 25–32 Read article
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A Review on Advances in Polymer Composites and Nanocomposites: Design, Applications, and Life Cycle Assessment
Abstract: Materials based on polymer composites and nanocomposites have won the main status in several regions of industry by mare possessing excellent properties and broad range of application. This review focuses on the advancements in the design of fiber-reinforced polymers, structural composites, multifunctional composites, and biomimetic and eco-friendly composites. Emerging developments in biomedical composites, polymer foams, and smart composites are explored, highlighting their applications in medical, aerospace, automotive, and structural engineering. …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 244–251 Read article
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Biohybrid Machines: Integrating Organic Systems with Robotics for Enhanced Mobility and Function
Abstract: Biohybrid machines are an innovative frontier at the intersection of biological systems and robotics. This research field explores the integration of living organisms with machines, combining the advantageous characteristics of both synthetic materials and biological components. Through the integration of organic cells, tissues, and even entire organisms with robotics, biohybrid machines possess unique capabilities such as self-healing, adaptability, and energy efficiency, making them more suitable for tasks that require flexibility …
Published in Trends in Machine design · Vol. 12, Issue 1, 2025 · pp. 30–37 Read article
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In Silico Assessment of Demethoxycurcumin: Molecular Docking and Computational Insights into its various therapeutic Potential
Abstract: Natural compounds are increasingly explored for their therapeutic potential in medical research. Here, we focused on demethoxycurcumin (DMC), a polyphenolic bioactive compound extracted from Curcuma longa, commonly found in turmeric. DMC, with a chemical formula of C20H18O5 and a molecular weight of 340 g/mol, possesses two aromatic ring systems, each featuring a β-diketone moiety connected by a seven-carbon chain. This unique structure allows DMC to engage in tautomerism, which is …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 9–15 Read article
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Applications of Nanomaterials in Soil Science and Agriculture: Enhancing Stability and Bioavailability through Nano-Encapsulation
Abstract: This research project focuses on the development and use of nanomaterials (NMs) for enhancing natural security in agricultural, feed, and food sectors. Protein-based and polysaccharide-based NMs, which self-assemble into micelle-like structures, have shown promise in improving the stability, bioavailability, and delivery of vital nutrients, agrochemicals, and medications through nano-encapsulation techniques. Nanomaterials such as modified nanoclays, including montmorillonite, have been employed in food packaging to enhance mechanical strength and create barriers …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 13, Issue 3, 2024 · pp. 23–28 Read article
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Jackfruit – A Protentional Fruit for Producing Functional Yogurt
Abstract: Jackfruit (Artocarpus heterophyllus), the largest tree-borne fruit, is a rich source of nutrition and medicinal properties. Native to the rainforests of the Western Ghats in India, its diverse varieties are celebrated across Asia for their unique texture, flavor, and nutritional value. The jackfruit is high in protein, carbohydrates, vitamins, and minerals, with its flesh and seeds offering various health benefits, including improved digestion, enhanced bone health, and cardiovascular support. Rich …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 14, Issue 1, 2025 · pp. 20–27 Read article
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GenChrome-ML: A Machine Learning Framework for Early Detection of Chromosomal Disorders Using Genomic Data
Abstract: The increasing burden of chronic disease and cancer demands innovative, more rapid and effective diagnostic tools in the field of healthcare. The majority of current diagnostic tools are dependent upon clinical symptomology and manual evaluation, leading to delays in early detection and treatment. The development of artificial intelligence (AI) and machine learning (ML), in recent years, has offered opportunities for the enhancement of disease prediction, diagnosis and personalization of treatment …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 2, 2026 Read article
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Scientific Trajectories in Indian Virology: Innovations, Institutions, and Impact
Abstract: India's substantial research on epidemiology, virology, and public health measures has helped the world understand viral infections better. This article gives an overview of virus research in India, starting with early studies on arboviruses and enteroviruses and going all the way up to current studies on new and re-emerging pathogens including SARS-CoV-2, Nipah, and Zika viruses. Over the decades, India has built a rich legacy in virus research through pioneering …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 · pp. 11–20 Read article
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CB₁ Reverse Agonists: A Cheminformatic and Patent Landscape Study
Abstract: The endocannabinoid system plays a crucial role in numerous physiological functions, making cannabinoid receptor 1 (CB1) an attractive target for therapeutic development. This review provides a systematic analysis of patent filings from 2019 to 2023 that focus on small-molecule CB1 reverse agonists. It begins with an overview of the endocannabinoid system, highlighting CB1’s involvement in energy balance, pain regulation, and neuroinflammatory processes The main section of the review examines fifteen …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 33–36 Read article
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Polymer-Based Ankle-Foot Orthoses: Innovations in Material Selection and Functional Enhancement
Abstract: Ankle-foot orthoses (AFOs) are critical devices in rehabilitative therapy for patients with foot drop due to neurological disorders such as stroke, multiple sclerosis, and cerebral palsy. These conditions impair dorsiflexion, making walking difficult and increasing the risk of falls. Traditional AFOs, often made from rigid thermoplastics, provide support but limit flexibility and patient comfort. Recent advancements in polymer chemistry have introduced innovative materials that enhance the functionality, durability, and effectiveness …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 49–55 Read article
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Accelerate Drug Development with Pharmacokinetic Softwares
Abstract: During continuously evolving technologies and mechanized equipments, there has been a tremendous growth in the pharmaceutical sector over the past few decades. New technologies, software, devices, and techniques are being developed or researched upon with each passing day. By leveraging pharmacokinetic software, researchers can efficiently analyze vast datasets from preclinical and clinical studies, extracting actionable insights that inform decision-making early in the development cycle. This predictive capability not only accelerates …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 3, 2024 · pp. 1–8 Read article
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Examining the Role of Synthetic Biology in Cellular Restoration Mechanisms
Abstract: Synthetic biology has emerged as a transformative field with the potential to revolutionize cellular repair mechanisms, offering innovative solutions to repair damaged DNA, stabilize proteins, regenerate tissues, and treat a wide range of diseases. By combining principles from genetic engineering, biotechnology, and computational biology, synthetic biology enables the design of cellular systems capable of performing functions that repair cellular damage and restore normal cellular processes. This article explores the application …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 19–29 Read article
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Exploring Robotic Arm Fabrication: An In-depth Review of Current Trends
Abstract: Robotic arms have emerged as indispensable tools across a myriad of industries, revolutionizing manufacturing processes, medical procedures, and even everyday tasks. This comprehensive review explores the recent advancements in robotic arm technology, focusing on key developments in design, control, sensing, and applications. The review begins by examining the evolution of robotic arm design, highlighting innovations in materials, actuators, and kinematic configurations that have enhanced the performance, versatility, and dexterity of …
Published in Journal of Control & Instrumentation · Vol. 15, Issue 3, 2024 · pp. 28–41 Read article
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An Insightful Study on SMEDDS Challenges and Potential Strategies
Abstract: Self-microemulsifying drug delivery systems (SMEDDS) have gained attention as an effective approach to enhance the bioavailability of poorly water-soluble drugs. They are innovative lipid-based formulations designed to enhance the solubility, bioavailability, and therapeutic efficacy of poorly water-soluble drugs. The development of SMEDDS involves systematic selection of components based on solubility and emulsification efficiency, followed by optimization of ratios using pseudo-ternary phase diagrams. The resulting formulations are evaluated for droplet size, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 311–334 Read article
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Veterinary Mycology: Fungal Infections in Livestock and Companion Animals
Abstract: Fungal infections represent a significant yet often underestimated challenge in veterinary medicine, affecting both livestock and companion animals. Veterinary mycology encompasses a diverse group of pathogens, including yeasts, molds, dimorphic fungi, and dermatophytes, that can cause localized or systemic diseases with substantial health, economic, and zoonotic implications. In livestock species, such as cattle, sheep, goats, poultry, pigs, horses, and camels, fungal infections manifest as dermatophytosis, mycotic mastitis, aspergillosis, keratomycosis, and …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 14, Issue 3, 2025 · pp. 44–51 Read article