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1841 articles for “humans” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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QSAR Analysis on a Series of Triazole Based Tubulin Polymerization Inhibitors
Abstract: AbstractThe polymerization progression of microtubules is vital to their natural capacities. Polymerization flow allows microtubules to embrace spatial courses of action that can change quickly because of cell needs and, at times, to perform mechanical work. Compounds that interfere with the microtubule-tubulin equilibria in cells are helpful in the treatment of human diseases. A few triazoles mimics of combretastatin-benzothiazole (CAB) hybrids had good activity as inhibitors both of tubulin polymerization …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 4, Issue 2, 2017 · pp. 5–20 Read article
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Biochemical and Structural Characterization of Helicobacter pylori Peptide deformylase by Computational Methods
Abstract: Helicobacter pylorus is classified as class one carcinogen in causing gastric cancer. Peptide deformylases (PDFs) present in bacteria removes the formyl group from the N-terminal Methionine of newly synthesized proteins which is necessary in protein maturation. These enzymes have shown as new targets in antibacterial, antimalarial and anticancer drug discovery. Here an insilico technique was initiated to characterize structural and biochemical properties of this protein. Pair wise sequence alignment with …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 4, Issue 3, 2017 · pp. 22–28 Read article
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Synthetic Viruses: A Review
Abstract: Fast advance in DNA synthesis and sequencing is leading the deliberate, large-scale hereditary change of organisms. Common objective of this new methodology is to advance our understanding of an organism's properties, especially its pathogenic ordnance in the event that it causes illness in people, and to make utilization of this new data to shield from, or treat, human viral disease. These new advances in DNA control have been stretched out …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 5, Issue 1, 2018 · pp. 28–34 Read article
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Nanotechnology Application in Neural Growth Support System
Abstract: With its ability to transfer electric impulses, make contact with neurons, and mimic the environment of neurons, carbon nanotubes have been intriguing candidates for the development of scaffolding that could promote neuronal growth and division. In order to encourage the growth and development of human brain cells, the researchers developed biodegradable composite scaffolding comprised of interconnected carbon nanotubes dispersed in the poly-L-lactic acid substrate. To imitate the guiding inputs of …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 24, Issue 2, 2022 · pp. 47–55 Read article
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Challenges and Possible Solutions in Plastic Pollution
Abstract: Plastics are extensively utilized in numerous industries due to their long-lasting nature, affordability, and adaptability, becoming an essential component of the worldwide economy. As societies produce waste, only a small portion of it is recycled, while the rest ends up in different ecosystems, causing harm to the environment and living organisms. The environmental degradation caused by plastics has raised significant concerns regarding their disposal. Nowadays hazardous waste is a serious …
Published in Journal of Water Pollution & Purification Research · Vol. 10, Issue 1, 2023 · pp. 22–27 Read article
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Isolation and Characterization of Lantibiotic Producing Lactic Acid Bacteria from Ambali, Aged Mango Pickle Probiotics
Abstract: Each year in the US at least 2 million people are sickened with antibiotic resistant infection. The development of antibiotics was one of the most important advances of medicine. Many bacterial infections (e.g. tuberculosis and infected wounds) that previously had no effective treatment and often killed people became treatable with antibiotics, saving millions of lives. Now, because of the overuse and misuse of antibiotics, bacterial infections that were once easily …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 3, Issue 3, 2016 · pp. 30–36 Read article
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Study of the Antimicrobial Potential of Consortiums of Hot Alcoholic Extract of Plants against Multidrug Resistant Bacteria Including One Vancomycin-Resistant Staphylococcus aureus (VRSA)
Abstract: Increasing antibiotic resistance exerts threatening implications in human health care. It subsequently increases the need to develop an alternative strategy to counter the growing concern against the superbug infection in open wounds. In the present study, two combinations of herbal alcoholic extracts have been assessed for antimicrobial activity against the isolates collected from human burn wound sample and biopsies. Total of 42 strains have been isolated and screened for its …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 9, Issue 3, 2019 · pp. 18–25 Read article
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Cinnamon Extract and Cinnamaldehyde Inhibit the Replication of T2 Bacteriophage in E. coli: Potential for Use in Antiviral and Anticancer Therapy
Abstract: An extract of cinnamon inhibits the growth of bacteria, viruses and cancer cells. At concentrations of 1, 2, 4, and 8 ml per 100 ml of Luria-Bertani broth, cinnamon extract had virtually no effect on the growth of E. coli. At the same concentrations, however, the yield of T2 bacteriophage was 98, 76, 64.5, and 61.8% of the control. Addition of cinnamon extract 37 min before infection produced a yield …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 9, Issue 3, 2019 · pp. 8–17 Read article
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Speech Perception in Geriatric Population
Abstract: Ageing is one of the characteristic features seen in organisms of the animal kingdom; after birth via ageing first the development and maturation take place which when progresses with time results in degeneration and ultimately ends with the end of the life cycle of the organism. As humans are no different; our maturation phase starts right after birth, which results in complete maturation by the time humans reach adulthood [1]. …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 6, Issue 2, 2019 · pp. 1–3 Read article
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A Review on Drug Delivery Systems Using Microfluidics
Abstract: AbstractMicrofluidics is undoubtedly an influential technology that is currently revolutionizing the chemical and biological studies by replicating laboratory benchtop technology on a miniature chip-scale device. In the area of drug delivery science, microfluidics offers advantages, such as accurate dosage, ideal delivery, target-precise delivery, sustainable and controlled release, several dosing, and slight side effects. These helps bring significant assets to the drug delivery systems. Microfluidic technology has been increasingly used for …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 10, Issue 1, 2020 · pp. 1–10 Read article
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Analysis of Total Hardness of Municipality Water of Amritsar City, Punjab
Abstract: The lather not produced while using soap which indicates hardness of water. Our life is sustenance with water which is one of the most primary needs for life. Water is mostly used for drinking, bathing, sanitary, washing, irrigation and agriculture. However water having high amount of hardness is considered to be the major threat to human health. The literature survey reports that 2.6 % water resources as fresh in the …
Published in Journal of Water Pollution & Purification Research · Vol. 10, Issue 3, 2023 · pp. 12–17 Read article
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Molecular Docking Approach on Thiazolidinedione Analogs as HIV-1-RT Inhibitors
Abstract: Potentially life threatening condition due to chronic syndrome caused by human immunodeficiency virus (HIV) is known as Acquired immunodeficiency syndrome(AIDS).Virus weakens the immune system of human being and body’s ability to fight against the organism, thereby causing the disease. When a person becomes infected with HIV, the virus attacks and weakens the immune system. In the given study, molecular docking study was performed on 30polysubstitutedThiazolidinedione (TZD) analogs as HIV-1 reverse …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 7, Issue 1, 2020 · pp. 1–6 Read article
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It is Not an Aberration, It is Fragment of our Correlated Viral Age
Abstract: Corona viruses are a cluster of allied contamination of germs that is originated in creatures and birds. In humanoid, corona viruses are rooted through respiratory, wheezing zone which infects the body and fluctuates from lightest to life threatening stage. The incurable classification of diseases are Severe acute respiratory syndrome-related corona virus (SARS), Middle East respiratory syndrome-related corona virus (MERS) and COVID-19. Till now, this contaminated germ disease does not have …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 8, Issue 2, 2021 · pp. 43–49 Read article
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The Constraining Mechanisms and Sustainable Environment
Abstract: Human relationship to the environment is degrading the environment. This has led to calls and appeals from all quarters of the earth for a sustainable environment—an environment that would continually provide our teeming needs and that of the future generation. However, in spite of these calls, nothing seems to be changing as regards man’s relationship with the environment—plundering of the environment still goes on apace. This research showed why these …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 9, Issue 1, 2019 · pp. 47–55 Read article
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Linking Data for Library Services
Abstract: AbstractSince its inception, the web is changing and evolving continuously to make the web more structured and accessible. It has evolved through the “web of hypertexts” into “web of data” where the data gets the primary citizenship of the web. Linked Data is a data-publishing technique that enables related data to be connected and easily accessible using common Web technologies. The data published could be read and interpreted not only …
Published in Journal of Advancements in Library Sciences · Vol. 3, Issue 1, 2016 · pp. 29–34 Read article
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The Ethical Challenge in Solving the Problem of Climate Change
Abstract: The reality of a changing climate with its attendant grave consequences is one problem that every living human and mostly those who have been enlightened about the causes of climate change should be talking about. The effects of a changing climate have the potentials of negatively affecting virtually every other sphere of life. Increased temperatures, floods, poor agricultural productivity, the growth and spread of dangerous strands of diseases among others, …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 9, Issue 2, 2019 · pp. 46–54 Read article
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Economics of Vegetable Seed Production in Arghakhanchi, Nepal
Abstract: Vegetable seed sector, though emerging both in area and production, knowledge regarding profitability and resource productivity is not clear among the seed producers. In this context, a study to estimate the economics of vegetable seed production was conducted in Arghakhanchi district of Nepal. Cost and return analysis showed that the average cost of production per Kg for bean, cowpea and pea seed was NRs. 145.78, NRs. 153.1 and NRs. 135.79 …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 8, Issue 2, 2019 · pp. 1–7 Read article
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Creative Use of Mobile Phone for Providing Quality Library Services
Abstract: AbstractThe present paper focuses on new trend in library and information science, i.e., mobile based library services. Mobile based service give faster access to academic user because it is more convenient, collaborative, and portable. At present day mobile become more basic need of human being. In changing era the mobile technology become more helpful to provide library services because tremendous change in information technology affects the user needs. Today the …
Published in Journal of Advancements in Library Sciences · Vol. 6, Issue 1, 2019 · pp. 32–34 Read article
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Information Seeking Behaviour of Faculty Members of Senior Colleges in Malshiras Taluka: A Study
Abstract: This paper deals with Information Seeking Behaviour of Faculty Members of Senior Colleges in Malshiras taluka: A Study. The man is a thinking animal so various kinds of thought and ideas are created in his mind. This human mind is a generator of ideals. These thoughts and ideas are based on certain facts which are derived by continuous observations and experiences. When these facts hold the test of time, they …
Published in Journal of Advancements in Library Sciences · Vol. 6, Issue 1, 2019 · pp. 106–110 Read article
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The ICT-driven Technical Education in India: An Evaluation of Project NPTEL
Abstract: The National Programme on Technology Enhanced Learning or commonly known as NPTEL is a project initiated by several Indian Institutes of Technology and Indian Institute of Science and funded by the Ministry of Human Resources and Development. Launched in 2003, it creates curriculum material pertaining to higher education covering science and technology. It provides freely accessible multimedia material for technical education. With the Indian economy growing at a fast pace, …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 10, Issue 1, 2020 · pp. 13–20 Read article