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102 articles for “pathophysiologically”
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Drug and Non-drug Treatment Options of Fibromyalgia
Abstract: Fibromyalgia (FM) treatment does not have a clear objective pathophysiological therapeutic goal. The management of this complex condition has thus perplexed the medical community for many years, and several national and international guidelines have aimed to address this complexity. Pain relieving pharmaceutical medications are generally connected with an assortment of unfriendly reactions, for example, constipation, urinary retention, nausea, sedation, respiratory depression, myoclonus, delirium, sexual dysfunction, and hyperalgesia. The challenge of …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 3, 2019 · pp. 15–23 Read article
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Ayurveda and Periodontal Disease: A Review
Abstract: Periodontal disease is inflammation of the surrounding structures of teeth. Prevalence of periodontal disease is significantly high in India. Modern dentistry suggests various measures to treat it. But because of being expensiveness of treatment and unavailability of trained dental professionals, especially in rural India, prevalence of periodontal disease is increasing day by day. Indian traditional medicine, ‘Ayurveda’ too suggest various treatment modalities which are inexpensive, effective and readily available even …
Published in Research and Reviews: A Journal of Dentistry · Vol. 3, Issue 3, 2012 · pp. 1–6 Read article
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Arterial Stiffness as an Antecedent in the Pathogenesis of Primary Hypertension
Abstract: Over the past 50 years, it has been postulated that abnormality in resistance vessels play an important and critical role in the pathogenesis of hypertension as these vessels maintain the steady-flow hemodynamic in the circulation. Accordingly, antihypertensive therapies were designed to alter the peripheral vascular resistance or cardiac output, resulting in a reduction in mean arterial pressure. However, in recent years, many studies have emphasized the role of arterial stiffness …
Published in Research and Reviews: A Journal of Health Professions · Vol. 7, Issue 3, 2017 · pp. 9–13 Read article
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A Review on Sarcopenic Obesity: A Rising Epidemic
Abstract: Age-related changes in body composition in geriatrics coupled with increased prevalence of obesity because of immobility and reduced activity gives rise to excess weight and reduced muscle mass or strength; the condition is recently defined as Sarcopenic obesity (SO).The prevalence of sarcopenia and Sarcopenic Obesity increases with age. Muscle and fat mass are strongly interconnected pathogenetically. A better understanding of the mechanisms which lead from loss of muscle mass to …
Published in Research and Reviews: A Journal of Health Professions · Vol. 5, Issue 3, 2015 · pp. 1–5 Read article
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Study of Polycystic Ovary Syndrome (PCOS) with Special Reference to Candidate Genes
Abstract: The PCOS (polycystic ovary syndrome) has become a worldwide concern as progression of PCOS in the age group of adolescence to postmenopausal women is increasing. In India, sudden rapid growth in PCOS is observed in the range of 3.7–22.5%. Effects of PCOS are not only on the reproductive and metabolic systems, but the whole body’s metabolism gets affected; ultimately, it leads to different life- style diseases like type 2 diabetes …
Published in Research and Reviews: A Journal of Health Professions · Vol. 13, Issue 1, 2023 · pp. 49–55 Read article
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Study of Platelet Count in Dengue Fever, Function and Their Importance in Hemostasis
Abstract: Dengue infection is a major vector-borne disease. Compatible hematological discovery comprises of vasculopathy, thrombocytopenia, and coagulopathy. The study comprises of 60 patients and all the cases were studied in the Department of Pathology, Kachchhi laboratory, Amreli, Gujarat, India. In this study, out of 60 cases, there were 12 cases of IgG positive and 31 cases of IgM positive. In which seven males had IgG infection and 18 males had IgM …
Published in Research and Reviews : A Journal of Immunology · Vol. 9, Issue 1, 2019 · pp. 1–3 Read article
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β-cell Deficit Due to Increased Apoptosis Islet Cell Plasticity in Humans Type 2 Diabetes
Abstract: Beta cells (β cells) in the pancreatic islets produces insulin and the number of functional insulin-producing β-cell contributes to the pathophysiology of type 2 diabetes . Type 2 diabetes is a chronic disease characterized by the deficiency in β-cells and increase in the levels of sugar in blood. β cells promote inflammation in obesity and type 2 diabetes. The low β-cell accumulation in Type 2 diabetes paves way to diabetes …
Published in Research and Reviews : A Journal of Immunology · Vol. 11, Issue 1, 2021 · pp. 1–7 Read article
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COVID-19: Impact on Human Health
Abstract: Researchers are on the cutting edge of devising the best strategy to combat the SARS-CoV-2 pandemic by studying and exploring the pathogenesis, prevention, and treatment as the world continues to be plagued by an increasing number of confirmed COVID-19 cases. The primary method for detecting the virus is via antigen testing and more accurate molecular tests such as rt PCR using patient samples. The most prevalent treatments for COVID-19 infection …
Published in Research and Reviews : A Journal of Immunology · Vol. 12, Issue 1, 2022 · pp. 1–8 Read article
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Chronic Kidney Disease: An Overview
Abstract: The key purpose of this review article is to throw light on chronic kidney disease (CKD). Each day people are diagonised with CKD making the need of proper awareness regarding CKD, one of the top public health priorities. Taking this into consideration, the review article outlines some new insight on identification of CKD, classifying it into several stages based on glomerular filtration rate (GFR)/chronic renal failure (CRF) value to be …
Published in Research and Reviews: A Journal of Medicine · Vol. 8, Issue 1, 2018 · pp. 6–9 Read article
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The Clinical Study on Conservative Therapy of Pediatric Intussusception: Caudal Block Improves the Success Rate
Abstract: Intestinal intussusception is one of diseases in which pediatric patient complain of acute abdominal pain and its morbidity is high. Therefore, it is necessary to diagnose and treat it swiftly but there are several difficulties for its treatment. Recently, there are many study and success for researching diagnosis and treatment of acute abdominal pain. Etiology and pathophysiology of intussusception are revealed so that noninvasive treatment is applied in clinical field. …
Published in Research and Reviews: A Journal of Medicine · Vol. 10, Issue 3, 2020 · pp. 29–34 Read article
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A Review on Treating and Managing Hypertension in Pregnancy
Abstract: Hypertension refers to increased arterial blood pressure. Studies show that disorders (pre-existing and gestational hypertension, preeclampsia, and eclampsia) due to hypertension are major cause of morbidity and mortality during pregnancy. During centuries we still do not have any specific treatment for hypertension in pregnancy. Hypertension during pregnancy occurs in about 6–8% of women. It is necessary to choose the optimal time and optimal therapy for hypertensive pregnancy disorders. Complication can …
Published in Research and Reviews: A Journal of Medicine · Vol. 11, Issue 1, 2021 · pp. 22–32 Read article
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A narrative review on cardiovascular disease due to the role of deficiency of Vitamin D and its management
Abstract: Cardiovascular disease is the prevalent cause of morbidity and mortality in the world, affecting many millions of individuals every year. Atherosclerosis, a chronic inflammatory condition that involves different cell types, several cytokines and adhesion molecules, is the underlying cause of cardiovascular disease. Vitamin D plays a pivotal role in bone homeostasis and calcium metabolism. Though, current research has specified additional helpful effects of vitamin D on the cardiovascular system. Vitamin …
Published in Research and Reviews: A Journal of Medicine · Vol. 11, Issue 2, 2021 · pp. 9–20 Read article
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Covid-19 Associated Mucormycosis: Urgency To Reconsider The Uncontrolled Use Of Prophylactic Drugs
Abstract: Mucormycosis, a lethal mycosis, has affected hundreds of COVID-19 sufferers in India. Mucormycosis, previously known as zygomycosis, is due to the diverse fungi that belong to the family "Mucorales." These molds are normally determined in soil, air, and damp partitions and often colonize oral mucosa, nose, paranasal sinuses, and throat. The pathophysiological results of diabetes mixed with the intense inflammatory surge in COVID-19 and steroid remedy weaken a person's immunity …
Published in Research and Reviews: A Journal of Medicine · Vol. 11, Issue 3, 2021 · pp. 12–17 Read article
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Benign ProstaticHyperplasia–EnhancementinPrevalence,EtiologyandManagement
Abstract: The goal is to learn more about the prevalence, etiology, treatment, and complications of benign prostatic hyperplasia. This is a 6-month retrospective study that covers people who have been diagnosed with BPH. The prevalence, etiology, management, and consequences of benign prostatic hyperplasia were investigated. By recognizing lower urinary tract symptoms and identifying an enlarged prostate, men can receive early treatment and limit the effects of benign prostatic hyperplasia. Benign prostatic …
Published in Research and Reviews: A Journal of Medicine · Vol. 11, Issue 3, 2021 · pp. 1–11 Read article
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Hemophilia and Gene Therapy–Review
Abstract: The coagulation factor VIII or factor IX genes are affected by the monogenic mutational illness known as hemophilia. Recombinant clotting factors, which are secure and efficient, are the preferred palliative therapy. In order to ensure steady and long-lasting concentrations of the damaged circulating factor, advanced therapies will be curative. Adeno-associated vectors have primarily been used, and the results have been positive in terms of amounts and timings of expression. These …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 3, 2024 · pp. 1–5 Read article
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Acute Ischemic Stroke: Diagnosis and Management Approach
Abstract: Stroke is the next chief reason of death worldwide and the foremost reason of debility, with a growing occurrence in emerging countries. Ischemic stroke produced by arterial obstruction is accountable for the majority of strokes. Management focuses on fast reperfusion with endovascular thrombectomy and intravenous thrombolysis, which together decreases debility but are time grave. The important primary stage in stroke maintenance is initial identification of patients with stroke and triage …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 10, Issue 3, 2020 · pp. 25–46 Read article
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Rectal Polyp may turn out to be Rectal Adenocarcinoma—Case Report Emphasize Histopathology as a Routine Measure
Abstract: AbstractAdenocarcinoma is a commonest type of colorectal cancer. For the primary care physicians, a review of the pathophysiology and clinical presentation are important in its diagnosis. In India the annual incidence rate of rectal cancer in men is 4.1 per 100000 populations. Colon cancer in women is 3.9 per 100000 populations. Causes of colorectal cancer include genetic and environmental factors or lifestyle-related factors. Some previous studies confirm colonoscopy as a …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 2, 2020 · pp. 19–23 Read article
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A Short Review on Mucormycosis/Black fungus
Abstract: The present article provides an outline regarding the mucormycosis, an angio invasive infection and an opportunistic condition with fungal infection that mainly targets the people who are with weaker immunity unable to fight with environmental pathogens due to other health related problems and people who are on long term medication and the present paper has been covered with all the information regarding the Predisposing factors, suspected diseased conditions, Targeted organs/tissues …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 10, Issue 1, 2021 · pp. 12–15 Read article
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Management of Polycystic Ovarian Syndrome (PCOS)
Abstract: The complex condition known as polycystic ovarian syndrome (PCOS) is characterized by chronic anovulation and hyperandrogenism. Depending on diagnostic criteria, 6–20% of females in reproductive age are afflicted. PCOS symptoms start to appear in the early pubertal years. Acne, anovulation, and irregular menstrual periods are features of PCOS and pubertal development in the average girl. The complex intertwined pathophysiology makes it difficult to identify the provoking factors. Most available scientific …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 11, Issue 2, 2022 · pp. 35–41 Read article
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Irritable Bowel Syndrome- Reviewed Through the Lens of Unani System of Medicine
Abstract: AbstractIrritable Bowel Syndrome (IBS) is recognized as the most common functional gastrointestinal disorder in the present medical scenario, affecting 11% of the population globally. It is characterized by diarrhea or constipation and sometimes both alternately. The pathophysiology of the disease is not much understood but it has been linked to colonic motility dysfunction inflammatory changes of the intestines, change in normal microflora of the gut and disturbance of enteric nervous …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 7, Issue 1, 2020 Read article