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201 articles for “pathological”
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Neuroprotective Effects of Curcuma longa: A Review of Its Role in Neurodegenerative Diseases
Abstract: Curcuma longa (turmeric), a perennial herb notably utilized in traditional medication, has garnered big clinical attention due to its major bioactive compound, curcumin. Curcumin, well-known shows a couple of organic activities, together with antioxidant, anti-amyloidogenic, and neurodegenerative effects, making it a promising candidate for the management of neurodegenerative diseases (NDDs), which include Alzheimer’s illness, Parkinson’s disorder (PD), Huntington’s sickness (HD), and amyotrophic lateral sclerosis (ALS). This evaluate consolidates current findings …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 3, 2025 · pp. 24–32 Read article
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Integrative Network Biology Analysis of GSE6011 Uncovers Molecular Signatures in Duchenne Muscular Dystrophy
Abstract: Duchenne muscular dystrophy (DMD) is a rare, severe neuromuscular disorder demonstrated by progressive skeletal muscle deterioration and premature mortality. Despite advances in supportive care, no definitive cure exists, highlighting the need to explore novel molecular targets. The current study aimed to uncover key dysregulated genes and molecular pathways in DMD through a dataset-specific network biology approach. Publicly available microarray data (GSE6011) from DMD quadriceps muscle biopsies of 22 patients and …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 3, 2025 · pp. 36–48 Read article
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A Comprehensive Review of Forensic Medicine: Its Evolution, Scope, Applications, and Future Directions
Abstract: Forensic medicine, a key junction of medical and law, has evolved substantially throughout the centuries, responding to scientific and technological advances. Forensic medicine, derived from the Latin term forensis, meaning “before the forum,” has evolved significantly over the centuries from rudimentary methods of determining the cause of death to a sophisticated and highly specialized medical discipline. Today, it encompasses a wide range of fields, including clinical forensic medicine, forensic pathology, …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 3, 2025 · pp. 18–28 Read article
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Comparative Effectiveness of Various Fungicides in Managing Mustard Clubroot Disease Caused by Plasmodiophora Brassicae
Abstract: The experiment was accomplished to find out which fungicide or fungicides work best against clubroot disease and how well they protect mustard plants. It also looked at how these fungicides affect the yield and other important growth factors of mustard. The study took place in the research field and lab of the Plant Pathology Division at the Regional Agricultural Research Station (RARS), Bangladesh Agricultural Research Institute (BARI), located in Jamalpur-2000, …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 15, Issue 1, 2026 · pp. 1–11 Read article
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Kisunla (Donanemab): A Novel Breakthrough Illuminating a Path to Better Alzheimer’s Outcomes
Abstract: Background: Alzheimer’s disease (AD) is a progressive neurodegenerative condition marked by cognitive decline, memory loss, and loss of independence. Despite decades of extensive research, disease-modifying treatments have been limited in success. Recent therapeutic advancements have led to the development of monoclonal antibodies targeting amyloid-beta (Aβ) plaques, particularly the pyroglutamate-modified variant, a key pathological hallmark of AD. Objectives: This review aims to explore the therapeutic potential of Donanemab (Kisunla), a novel …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 3, 2025 · pp. 37–45 Read article
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Efficacy of New Fungicides in Controlling Powdery Mildew of Sweet Gourd
Abstract: This experiment was conducted at the Plant Pathology Division, Regional Agricultural Research Station (RARS), Jamalpur, Bangladesh during 2025 of Rabi & Kharif-1 seasons to find out the effectiveness of new fungicides against Powdery mildew disease of sweet gourd. Twenty (20) new fungicides viz. Acrozet 50 WP, Qingdao GBW, Hea 10 FC, Top star 32.5 SC, Nila 80 WP, Soazeb 72 WP, Safezeb 80 WP, Canvas 32.5 SC, Pyzim 50 WP, …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 14, Issue 3, 2025 · pp. 134–142 Read article
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Screening of Mustard Varieties and Lines against Clubroot and Alternaria Leaf Spot Diseases
Abstract: The experiment was conducted to find out the resistant varieties/lines against clubroot and Alternaria leaf spot diseases of mustard at the Plant Pathology Division, RARS Jamalpur, Bangladesh during the Rabi season of 2024-2025 with sixty-two (62) varieties and lines of Mustard collected from Oilseed Research Centre (ORC) and Plant Genetic Resources Centre (PGRC), Joydebpur, Gazipur-1701, Bangladesh. To screen for clubroot and Alternaria leaf spot diseases and to evaluate yield and …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 14, Issue 3, 2025 · pp. 97–106 Read article
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Speech and Swallowing Impairments in Herpes Zoster: A Case Report
Abstract: Herpes zoster (HZ), caused by reactivation of varicella-zoster virus, can extend beyond dermatological manifestations to involve cranial nerves, resulting in complex speech and swallowing deficits. This case report presents a 54-year-old male with herpes zoster–related cranial neuropathy, who developed unilateral vocal fold paralysis, dysphonia, and dysphagia. Comprehensive assessment included perceptual, acoustic, endoscopic, and patient-reported outcome measures. Perceptual voice evaluation revealed severe dysphonia with breathiness, asthenia, strain, and reduced loudness, confirmed …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 3, 2024 Read article
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A Study of Optical Sensor in Clinical applications
Abstract: The escalating demand for precise, real-time, and minimally invasive diagnostic and monitoring tools in clinical practice has propelled the development of sophisticated sensor technologies. Among these, optical sensors have emerged as a cornerstone, leveraging the interaction of light with biological matter to translate molecular or cellular events into quantifiable signals. Their inherent advantages – including high sensitivity, specificity, rapid response times, non-ionizing nature, and potential for miniaturization – make them …
Published in International Journal of Optical Innovations & Research · Vol. 3, Issue 2, 2025 · pp. 1–7 Read article
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Assessing the Effectiveness of New Fungicides Against Potato Late Blight Disease (Phytophthora Infestans)
Abstract: An experiment was conducted in the field of the Plant Pathology Division, Regional Agricultural Research Station (RARS), Bangladesh Agricultural Research Institute (BARI), Jamalpur, Bangladesh during the rabi season of 2024–2025 to determine the appropriate chemical fungicide for controlling late blight disease of potato. The evaluation included twenty-five new fungicides approved by the Pesticide Technical Advisory Committee (PTAC), Bangladesh, along with a standard control (Ridomil Gold MZ 68 WG) and an …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 15, Issue 1, 2026 · pp. 28–38 Read article
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Bone Grafting in Dentistry: From Biological Principles to Contemporary Regenerative Applications
Abstract: Bone grafting plays a pivotal role in contemporary regenerative dentistry by enabling predictable reconstruction of alveolar bone defects resulting from periodontal disease, tooth extraction, trauma, or pathology. Adequate bone volume and quality are essential prerequisites for successful implant placement, periodontal regeneration, and long-term functional and esthetic outcomes. Bone graft materials act as biological or synthetic scaffolds that facilitate new bone formation through the primary mechanisms of osteogenesis, osteoinduction, osteoconduction, and …
Published in Research and Reviews: A Journal of Dentistry · Vol. 17, Issue 1, 2026 · pp. 6–13 Read article
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Comprehensive Study and Triggering Factors of Alcoholic and Non-Alcoholic Fatty Liver
Abstract: Over the past few years, fatty liver disease has turned out to be a rather widespread phenomenon and has become a serious issue with the global population nowadays. It comprises alcoholic fatty liver disease and non-alcoholic fatty liver disease, which develop under the influence of various initiating factors, though frequently follow similar pathologies. The overloading of lipids in the hepatocytes in most cases will be the first sign of the …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 43–52 Read article
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Vitamin D Mitigates Inflammation and Downregulates Importin α3 in Non-Alcoholic Fatty Liver Disease (NAFLD)
Abstract: Non-alcoholic fatty liver disease (NAFLD) affects about one-third of the population in the United States and Western countries, reaching up to 90% among obese individuals and those undergoing bariatric surgery. Characterized by hepatic fat accumulation, NAFLD progresses from simple steatosis to non-alcoholic steatohepatitis (NASH), fibrosis, and, in rare cases, hepatocellular carcinoma. Linked intricately with metabolic syndrome, including diabetes and obesity, NAFLD development involves insulin resistance and hyperinsulinemia. Experimental evidence consistently …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 Read article
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Management of Kosthasakhashrita Kamala W.S.R. to Hepatocellular Jaundice – A Case Study
Abstract: Kosthasakhāśrit Kamala is a well-recognized clinical entity in Ayurveda and is widely correlated with modern hepatocellular jaundice. The condition arises primarily due to the vitiation of Pitta dosha within the Kostha (gastrointestinal tract), which subsequently spreads to the Sakha (peripheral tissues). Classical texts describe hallmark features such as Haridra Netra (yellowish discoloration of the eyes), yellowish hue of twak and nakha, pitta varṇa of mutra and sakrit (yellow urine and …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 · pp. 1–8 Read article
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Ayurvedic Nutritional Interventions for Menstrual and Reproductive Health: A Narrative Review
Abstract: Menstrual health is a reflection of a woman’s reproductive health. A proper understanding of menstrual patterns helps in assessing women’s overall health. The menstrual period is a vital process involving endometrial regeneration and the initiation of follicular growth, which ultimately builds the foundation for a healthy offspring. Ayurveda describes various unique regimens for women. Adherence to these regimens helps prevent and manage growing menstrual disorders and infertility, along with the …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 1, 2026 · pp. 1–5 Read article
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Shadows of Uncertainty: When Pneumonia Isn’t Pneumonia
Abstract: Pneumonia is a common medical condition encountered in hospitalized patients and remains a cause of morbidity worldwide. Identifying and initiating appropriate treatment in febrile patients who present with respiratory symptoms and radiographic infiltrates, reduce hospital stay, minimize complications, and lower healthcare costs. However, the assumption that every pulmonary infiltrate or opacity seen on a radiological imaging represents an infectious process such as pneumonia can lead to misdiagnosis, unnecessary investigations, prolonged …
Published in International Journal of Pathogens · Vol. 3, Issue 1, 2026 · pp. 24–29 Read article
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Anticancer Potential and Other Therapeutic Activities of Curcumin & Its Derivatives
Abstract: Curcumin, a compound isolated from turmeric, is used in the management of various diseases due to its extensive medicinal properties. Curcumin, the principal polyphenol isolated from Curcuma longa (turmeric), has garnered immense scientific interest for its extensive medicinal properties, including potent anti-inflammatory, antioxidant, and anticancer activities demonstrated in preclinical models. An expanding body of research indicates broad therapeutic promise in managing diverse pathologies, from various cancers to chronic inflammatory, metabolic, …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 19–28 Read article
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The Parasitic Fingerprint: Tracing Infection to Host Illness
Abstract: Parasitic infections remain a major global health burden, causing significant morbidity and mortality, particularly in tropical and subtropical regions. A critical aspect of disease pathogenesis is the unique molecular and cellular imprint left by parasites in their hosts, termed the “parasitic fingerprint.” These fingerprints encompass parasite-derived proteins, nucleic acids, metabolites, extracellular vesicles, and host responses, including gene expression changes, cytokine profiles, and metabolic adaptations. Advances in multi-omics technologies, which integrate …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 1, 2026 · pp. 29–50 Read article
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Developing an Assessment Protocol in Ayurvedic Research for Hyperemesis Gravidarum with Special Reference to Garbhini Chardi
Abstract: Garbhini Chardi (nausea and vomiting in pregnancy) is described in Ayurvedic texts as one of the Vyakta Garbha Lakshanas – early physiological signs indicating pregnancy. However, when this symptom becomes excessive, persistent, or distressing, it may transition from a normal event to a pathological condition, requiring timely intervention to safeguard maternal and fetal health. In advanced stages, it leads to day-to-day incapacitation, weight loss, dehydration, and metabolic disturbances – clinically …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 · pp. 44–61 Read article
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Cellular Mechanisms of Autophagy in Carcinogenesis: A Narrative Review
Abstract: Autophagy is a highly conserved lysosomal degradation pathway essential for cellular homeostasis, metabolic adaptation, and survival under stress. In the context of carcinogenesis, autophagy exhibits a paradoxical and stage-dependent role. During early tumor development, autophagy acts as a tumor-suppressive mechanism by limiting genomic instability, oxidative stress, and chronic inflammation. Conversely, in established malignancies, cancer cells exploit autophagy to sustain growth, survive hostile tumor microenvironments, and resist anticancer therapies. Increasing evidence …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 1, 2026 · pp. 23–28 Read article