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175 articles for “Lead compound.”
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Decompensated Liver Failure and Acute Renal Failure in a Patient with Chronic HBV,HCV, and HIV Infections
Abstract: This case study focuses on a 30-year-old male patient suffering from decompensated liver failure and acute renal failure, complicated by chronic hepatitis B (HBV), hepatitis C (HCV), and HIV/AIDS. Presenting with severe abdominal pain, nausea, and general weakness, the patient had a history of alcohol and intravenous drug use, leading to chronic liver disease and acute renal failure. Despite aggressive interventions, including intravenous antibiotics and fluid therapy, his condition worsened …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 17–23 Read article
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Electoral Engagement and Political Representation: An Analytical Study of Women’s Participation in India’s Democratic Process
Abstract: This study investigates the persistent disconnect in women’s political participation in India, where their consistently high voter turnout stands in stark contrast to their minimal presence in Parliament. Although constitutional provisions guarantee equality and women demonstrate strong engagement as voters, their representation within formal political structures remains disproportionately low. Using the 2024 Lok Sabha elections as a primary reference point, the research interrogates core questions surrounding this imbalance: Why does …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 15, Issue 3, 2025 · pp. 1–23 Read article
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A study on Bridging Chemical Transformation and Climate Feedbacks in the Earth System
Abstract: The atmosphere operates as a vast and complex chemical reactor, where minute-scale transformations exert profound influence on planetary-scale climate stability. This research investigates the multi-scale coupling between reactive tropospheric chemistry and large-scale climate feedbacks, challenging traditional modeling approaches that often divorce chemical kinetics from dynamic processes. By integrating high-resolution chemical transport models (CTMs) with comprehensive Earth System Models (ESMs), we map the flow of energy and matter from the molecular …
Published in International Journal of Climate Conditions · Vol. 2, Issue 2, 2025 · pp. 1–8 Read article
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Dynamic Approach to Evaluate Costing through Software with Integration of CAD/CAM
Abstract: This paper provides the approach to evaluate costing of a model through the use of CAD/CAM integration with establishing rules and scripting. Costing includes the direct and indirect cost of the product. The earlier process of cost estimation was laborious for engineers and it takes long time to evaluate the cost of a finished product. This methodology provides the knowledge to integrate software technology with production knowledge by establishing the …
Published in Trends in Machine design · Vol. 5, Issue 1, 2018 · pp. 21–32 Read article
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Flavonoids Regulate Airway MUC5AC Mucin Expression through Modulation of Multiple Signalling Pathways
Abstract: Airway mucus is a component of pulmonary innate immune function and plays very important role in defense against invading pathogenic microbes, chemicals and particles. The protective function of airway mucus is attributed to the viscoelasticity of mucins. Mucins are large glycoproteins play important role in cell–cell adhesion, airways protection, Nuclear-factor kappa B signalling, epidermal growth factor receptor signalling. Eleven mucin genes (among twenty identified mucin genes) have been expressed at …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 7, Issue 3, 2017 · pp. 21–33 Read article
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A Review on Psidium Guajava
Abstract: Psidium guajava is an evergreen shrub belongs to Myrtaceae family and commonly known as guava. It contains phenolic compounds and acts as anti-oxidant properties as well as immunostimulant. It has a higher number of vitamins and minerals. Every part of this plant contains various phytochemicals like quercetin, rutin, kaempferol, gallic acid, epicatechin, ursolic acid, glucosides, guavanoic acid, guava coumaric acid, saponins, terpenoids are present. It shows various pharmacological activities like …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 10, Issue 3, 2021 · pp. 9–14 Read article
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The Concept of Guillain-Barré Syndrome (GBS) in Unani Medicine and the Potential Role of Unani Pharmacology in Its Management
Abstract: Introduction: Guillain–Barré Syndrome (GBS) is an autoimmune neurological disorder characterized by progressive muscle weakness and paralysis due to immune-mediated damage to the peripheral nervous system. Conventional treatments focus on immunotherapy and supportive care, but alternative approaches, such as Unani Medicine offer promising holistic management strategies. Unani Medicine attributes GBS to humoral imbalance, particularly an excess of Balgham (Phlegm) affecting nerve function, leading to weakness and dysfunction. Objective: This study aims …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 2, 2025 · pp. 32–52 Read article
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Revolutionizing the Delivery and Efficacy of Nutraceuticals
Abstract: The global nutraceutical market is on a remarkable growth trajectory, fueled by a growing public focus on preventive health and expected to surpass USD 900 billion by 2030. However, a major roadblock stands in the way of many promising bioactive compounds—like resveratrol, curcumin, and omega-3s—reaching their full potential: their poor absorption by our bodies. Issues like low solubility in water, instability in the gut, and rapid metabolism lead to notoriously …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 638–647 Read article
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Therapeutic Potential of Silver: An Overview
Abstract: Metals play an important role in human body, the deficiency of which leads to various disorders. Earlier there was a perception that metals are not compatible to human body at all, but now it has been reported that numbers of metallic compounds are essential for body and some are in the category of essential elements. Metals are present in human body in different concentration and combination at various sites and …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 4, Issue 1, 2014 · pp. 23–28 Read article
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Enhancement of Some Pharmaceutically Important Secondary Metabolites By in vitro Techniques
Abstract: AbstractSecondary metabolites are economically important as drugs, dyes and pigments, pesticides, and food additives. The evolving commercial importance of secondary metabolites has in recent years resulted in a great interest in mechanism of secondary metabolism, especially in the production of bioactive plant metabolites by means of tissue culture technology. Plant cell and tissue culture technologies can be established for both multiplication and extraction of secondary metabolites. Strain improvement, methods for …
Published in Research & Reviews : Journal of Herbal Science · Vol. 3, Issue 1, 2014 · pp. 6–14 Read article
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Plant Bioactive Metabolites and Their Role in the Prevention and Control of Dental Diseases and Infections.
Abstract: The oral diseases, including dental caries and periodontitis, affect masses worldwide, and have historically been managed with synthetic antimicrobials that cause deleterious side effects, leading to mounting bacterial resistance. Consequently, contemporary dentistry is rapidly shifting toward phytomedicine using plant bioactive molecules, such as polyphenols, terpenes, anthraquinones (berberin, eugenol, curcumin, catechins, allicin, and azadirachtin. These compounds offer potent antimicrobial, anti-inflammatory, and tissue-regenerative properties that are crucial for preventing and curing dental …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 47–66 Read article
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Title-: Hello! Are we alone? If you're like me, you may want to know me
Abstract: A thin layer near the surface of Earth is teeming with life of huge diversity: from micro-organisms to plants, animals, and possibly even more intelligent species humans !. Up till now, human forms the only known samples of intelligent civilized life in the Universe? We humans accepted that the laws and concepts of physics and chemistry can be applied throughout entire cosmos. Is there then a general biology as well …
Published in Research & Reviews : Journal of Space Science & Technology · Vol. 8, Issue 3, 2019 · pp. 1–22 Read article
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Phytochemical, Acute Toxicity and Heavy Metals Evaluation of Khaya senegalensis (Desr.) A. Juss (Meliaceae) Stem Bark
Abstract: The present work was aimed to determine the phytochemical constituents, median lethal dose (LD50) and levels of heavy metals in Khaya senegalensis stem bark obtained from Kano State, Nigeria. The preliminary phytochemical screening revealed the presence of steroids, terpenoids, alkaloids, anthraquinones, saponins, phenolic compounds and carbohydrates, while the LD50 of the aqueous stem bark extract was above 5000 mg/kg body weight using OECD and Lorke’s method. The heavy metals analysis …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 7, Issue 1, 2020 · pp. 1–7 Read article
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The State of Air Quality: Pollution Sources, Health Implications, and Future
Abstract: Air quality is a critical component of environmental health, significantly affecting human well-being and ecological balance. Poor air quality has been related to a variety of health issues, including respiratory and cardiovascular disorders, and it is a major cause of early death worldwide. Understanding the origins, kinds, and impacts of air pollutants is critical for establishing effective pollution-reduction initiatives. This review focuses on the principal pollutants that affect air quality, …
Published in International Journal of Atmosphere · Vol. 1, Issue 2, 2024 · pp. 1–4 Read article
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Phytoconstituents of Eclipta alba Targeting Various Protein Sequences of Coronavirus: An Insilco Approach
Abstract: Abstract Background: The major disaster in the 21st century is the Novel-Coronavirus 2019 (nCoV or COVID-19) and Severe Acute Respiratory Syndrome-related coronavirus (SARS-CoV). In the year 2019, a new strain of coronavirus (CoV) was recognized in Wuhan city of China. In the current scenario there is no specific drug or therapy is for treating COVID-19 infections which is turning to be extremely fatal. Based on the literature survey for natural …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 7, Issue 2, 2020 · pp. 28–51 Read article
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Phyto Biotics in Aquaculture
Abstract: This paper aims to assess the existing knowledge on the use and effects of phytobiotics in fish farming, as well as their potential for broader application in aquaculture. With the rising demand for fish, there has been a noticeable decline in fish production in recent years, which could be a driving factor behind the increasing interest in using phytobiotics in this field. The main factor contributing to the decrease in …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 13, Issue 2, 2024 · pp. 18–22 Read article
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Screening Phytocompounds of Tinospora cordifolia to Find Potential Drug Targets for Cystic Fibrosis
Abstract: This study aimed to evaluate the therapeutic potential of phytocompounds derived from Tinospora cordifolia in treating cystic fibrosis (CF), a genetic disorder caused by mutations in the CFTR gene that lead to severe respiratory and digestive complications. Phytocompounds were retrieved from the IMPPAT database and subjected to molecular docking simulations using PyRx to assess their binding affinity to the CFTR protein. The top-scoring compounds – sterol, magnoflorine, tembetarine, kaempferol, and …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 16–24 Read article
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Induction of G1 Phase Cell Cycle Arrest and Apoptosis in Breast Cancer MCF-7 Cells by Sulphonamide Derivative CID-6861424
Abstract: Breast cancer is most frequently detected and leading cause of cancer death in women worldwide. 80% of the breast cancer are estrogen receptor positive and the presently available drugs are ineffective either due to intrinsic resistance or due to acquired resistance. Sulfonamide compounds are a class of compounds showing activities like, antibacterial, antiviral including antitumor. In the present study we have investigated the anti-cancerous activity of sulfonamide derivative CID-6861424 on …
Published in Research and Reviews: A Journal of Toxicology · Vol. 9, Issue 2, 2019 · pp. 1–17 Read article
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Modified Solution Combustion Approach for Probing of Structural and Dielectric Properties of Sm3+ Doped GdAlO3 Nanoparticles
Abstract: A modified solution combustion approach was used in the preparation of nanosized Gd1xSmxAlO3 (x=1, 3, 5, 7, 9 mol%) using mixture of ODH and novel fuel E. tirucalli plant latex as fuels with corresponding metal nitrates. The structural morphology of synthesized and calcined powders are revealed using various analytical techniques such as Powder X-ray diffraction (PXRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR) and …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 10, Issue 1, 2020 · pp. 16–25 Read article
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Assess the Knowledge Regarding Usage of Plastic Leading to Cancer Risk and Their Preventive Measures Among House Wives in Selected Area Vaniyamkulam
Abstract: This study explores the level of awareness among housewives in Vaniyamkulam about the potential cancer risks associated with the use of plastic materials in households, along with their knowledge of preventive measures. The proliferation of plastic usage in daily life has raised significant health concerns, particularly its potential to release carcinogenic compounds such as bisphenol A and dioxins, which can leach into food and beverages. Given the critical role housewives …
Published in International Journal of Oncological Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 12–17 Read article