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932 articles for “Safety”
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Overcoming Obstacles to an HIV-1 Cure: Advances in Genome Editing, Immune System Reprogramming, and Viral Reservoir Elimination
Abstract: Human immunodeficiency virus type-1 (HIV-1) continues to represent a major global health challenge despite the remarkable success of antiretroviral therapy (ART). Although ART effectively suppresses viral replication and prolongs survival, it cannot eradicate the virus due to the persistence of long-lived latent reservoirs. In recent years, innovative therapeutic strategies have been explored with the aim of achieving either a functional remission or complete viral elimination. Advances in genome-editing technologies, particularly …
Published in International Journal of Virus Studies · Vol. 3, Issue 2, 2026 Read article
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In Vivo Hypoglycemic Activity of Aqueous Leaf and Root Extracts of Macaranga Barteri Müll. Arg. (Euphorbiaceae) In Swiss Albino Mice
Abstract: Background: Macaranga barteri Müll. Arg. is a perennial plant in the family Euphorbiaceae and is used in African traditional medicine for the management of several ailments, including diabetes. Although the leaves and stem bark have been studied for various pharmacological activities, little is known about the therapeutic value of the roots. Objective: This study evaluated the in vivo hypoglycemic activity of aqueous leaf and root extracts of M. barteri in …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 15, Issue 2, 2026 Read article
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Comparative Study of Knowledge and Attitudes of Rural-Urban Households on Polio Vaccination in Northeast Nigeria
Abstract: Poliomyelitis (polio), although it has been eradicated over the decades, continues to be a major problem of public health in Nigeria. Polio vaccination is the best way to counteract the transmission of poliovirus, although differences in knowledge and attitude to polio vaccination between rural and urban families are present and especially in Northeast Nigeria. This paper explores such differences, evaluates their impact on the knowledge, attitudes, and acceptance of polio …
Published in International Journal of Children · Vol. 3, Issue 2, 2026 · pp. 1–13 Read article
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Novel 1,3,4-Thiadiazole Derivatives: Design, Synthesis, Characterization and Anticancer Evaluation – A Review
Abstract: Cancer remains one of the leading causes of mortality worldwide despite significant advances in diagnosis and treatment. The clinical usefulness of many anticancer drugs is often restricted by toxicity, poor selectivity, and the emergence of drug resistance. These limitations have encouraged the search for novel heterocyclic compounds with improved therapeutic efficacy and safety. Among these, the 1,3,4-thiadiazole scaffold has gained considerable attention because of its favorable physicochemical characteristics, metabolic stability, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
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Agentic AI: Architectures, Types, Capabilities, Mathematical Equations and Governance in the Era of Autonomous Intelligence
Abstract: Agentic Artificial Intelligence (Agentic AI) represents a major advancement in the evolution of intelligent systems by enabling autonomous planning, decision-making, and action execution. Unlike traditional AI models, which are primarily reactive and designed to respond to predefined inputs, Agentic AI systems possess capabilities such as memory, reasoning, goal-oriented planning, tool integration, and dynamic adaptation to changing environments. These characteristics allow them to perform complex, multi-step tasks with minimal human intervention, …
Published in Recent Trends in Mathematics · Vol. 3, Issue 2, 2026 Read article
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Layered Metal–Polymer Hybrid Laminates with Embedded Impact Sensors for Connected Automotive Panels
Abstract: The increasing demand for lightweight, intelligent, and structurally reliable automotive components has accelerated the development of multifunctional hybrid materials capable of simultaneously providing superior mechanical performance and real-time structural health monitoring. In this study, a novel layered metal-polymer hybrid laminate incorporating an embedded flexible impact sensor was developed for connected automotive panel applications. The laminate was fabricated using AA6061-T6 aluminum alloy face sheets and a thermoplastic polyurethane interlayer through hot-press …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 Read article
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Smart Iron Box with Automatic Cloth Detection and Heat Adjustment
Abstract: Ironing continues to be a lengthy and sometimes monotonous activity in domestic chores; especially among those with busy schedules who need to ensure efficiency and minimize risks of harming delicate fabrics. This document discusses the design and development of an intelligent ironing machine that performs ironing tasks using embedded computing and multi-sensor fabric identification. Unlike traditional irons that depend entirely on the manually chosen temperatures and user discretion, the developed …
Published in International Journal of Electrical and Communication Engineering Technology · Vol. 4, Issue 2, 2026 Read article
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IoT-Based Motor Protection and Control System Using PLC and ESP8266
Abstract: Because of their straightforward design and affordable price, single-phase induction motors are frequently utilized in residential and small-scale industrial settings. However, conventional direct-on-line (DOL) control provides fixed-speed operation and offers limited protection against thermal overload and fault conditions. This article describes the design and implementation of an ESP8266 Node MCU-based PLC- based closed-loop motor control system with Internet of Things features. To increase operating flexibility and maintenance efficiency, the suggested …
Published in International Journal of Electrical Power and Machine Systems · Vol. 4, Issue 1, 2026 · pp. 54–62 Read article
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Solanum viarum Dunal: Ethnomedicinal Importance, Phytochemical Profile and Pharmacological Potential — A Comprehensive Review
Abstract: Solanum viarum Dunal, commonly known as tropical soda apple or Sodom apple, is a medicinally important plant belonging to the family Solanaceae. The plant has been widely utilized in traditional medicine systems for the treatment of fever, cough, skin disorders, inflammation, gastrointestinal ailments, and microbial infections. The present review comprehensively summarizes the ethnomedicinal importance, phytochemical profile, pharmacological activities, and pharmaceutical significance of S. viarum. Literature reports indicate that the plant …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 3, 2026 Read article
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Integrative Therapeutics for Antimicrobial Resistance and Autoimmune Disease: Evidence and Pathways
Abstract: Background: Antimicrobial resistance (AMR) is accelerating globally, while autoimmune diseases and adverse drug reactions (ADRs) continue to rise. Ayurveda offers immunomodulatory, antimicrobial, and detoxification‑oriented interventions that may complement biomedical strategies. Objective: To propose a hypothesis‑driven integrative model combining Ayurvedic phytotherapy, panchakarma detoxification, and personalized dosha‑based care with evidence‑based medical management to mitigate AMR emergence, modulate autoimmunity, and reduce ADR incidence. Methods: A synthesis of mechanistic literature on Ayurvedic herbs with …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 2, 2026 · pp. 25–30 Read article
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POLYMER AND COMPOSITE-BASED GEOSYNTHETIC REINFORCEMENTS FOR SEISMIC STABILITY OF SOIL RETAINING STRUCTURES: MATERIALS, MECHANICS, AND PERFORMANCE REVIEW
Abstract: Geosynthetic materials based on polymer and composites have become important items for the structural performance and seismic resilience of the reinforced soil retaining systems. Mechanically stabilized earth walls in recent geotechnical engineering practice are increasingly based on enhanced polymeric reinforcements for enhanced tensile strength, durability, flexibility, and energy dissipation under dynamic loading. High-density polyethylene, polypropylene, polyester, and fiber-reinforced polymer composites are usually used. The present review focus on the recent …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Transfer Learning Based High-Precision Multi-Class Object Detection for Real-Time UAV Autonomous Landing via YOLOv8l in Unstructured Scenarios
Abstract: A significant challenge for autonomous drone landings in unstructured environments is that of reliably detecting and identifying objects in real-time to ensure safety and accuracy of the landing area. This paper presents a well-founded method for solving this problem using the YOLOv8l object detection framework to detect landing zones, obstacles and people in the relevant vicinity of the landing area. The dataset used for the training of the model contained …
Published in Journal of Aerospace Engineering & Technology · Vol. 16, Issue 2, 2026 Read article