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1260 articles for “CTLA-4”
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Building Scalable Microservices with Micronaut, Kotlin, and AWS DynamoDB: A Comprehensive Architecture Study
Abstract: The evolution of enterprise software has trended steadily toward microservice architectures due to their inherent scalability and resilience advantages over monolithic systems. This research explores a comprehensive implementation approach using Micronaut, an innovative JVM-based framework specifically designed for resource-efficient microservices. The study combines Micronaut with Kotlin programming language and leverages AWS DynamoDB as a scalable NoSQL persistence layer, with Apache Kafka providing event-driven communication capabilities. We explore the critical role …
Published in Journal of Mobile Computing, Communications & Mobile Networks · Vol. 12, Issue 2, 2025 · pp. 40–57 Read article
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Advances in Polymer-Modified Concrete using XAI
Abstract: Industry 4.0 technologies are being quickly adopted by the construction sector, opening new avenues for enduring operational and environmental issues. This sector looks at how explainable AI can forecast air and enhance the quality of building materials. XAI, AI, ML, and big data drive a new paradigm in polymeric material development. The effective XAI and ML-assisted design creates innovative, high-performance polymeric materials. It covers building a database and representing structures, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 133–144 Read article
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Cost-Effective Conversion Techniques of Scrap Bicycles into Intelligent Electric Bicycles: A Review
Abstract: Over the past few years, there has been an overwhelming increase in requirement of sustainable and affordable urban mobility solutions both due to the environmental concerns along with the rising fuel prices and urban traffic jams. Electric bicycles (e-bike) have become an efficient option as a substitute to traditional modes of transport which are similar to conventional tools since they have low emissions and are energy efficient as well as …
Published in Journal of Automobile Engineering and Applications · Vol. 12, Issue 2, 2025 · pp. 30–40 Read article
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Study of a Western Disturbance of 2023 Using Satellite-Based Observation, Reanalysis Data, and Numerical Simulation
Abstract: Western Disturbances (WDs) are synoptic-scale, extratropical storm systems that influence winter precipitation across northwest India. This study focuses on a specific WD event that occurred from 24– 25 March 2023, affecting Jammu & Kashmir, Himachal Pradesh, Uttarakhand, and Punjab. The analysis integrates satellite observations, ERA-5 reanalysis data, and simulations from the Weather Research and Forecasting (WRF) model to evaluate the model's performance. The novelty of this study lies in its …
Published in Journal of Remote Sensing & GIS · Vol. 16, Issue 3, 2025 · pp. 16–38 Read article
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A Review of Failure Investigations and Its Techniques
Abstract: Valve failure poses a significant financial risk in the offshore oil and gas industry. Serious repercussions from this problem could include property damage and lost output from operational shutdowns. Additionally, it can lead to serious health, safety, and environmental (HSE) concerns such as oil and gas leaks, environmental contamination, and potential fatalities. In the Norwegian offshore industry, different kinds of valve failures have happened for a number of reasons, including …
Published in Journal of Thermal Engineering and Applications · Vol. 12, Issue 2, 2025 · pp. 33–41 Read article
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Prevalence and Risk Factors of Neglected Tropical Diseases Among Women and Children in Rural Liberia: A Regional Perspective
Abstract: Neglected Tropical Diseases (NTDs) remain a critical public health challenge in Liberia, disproportionately affecting women and children in rural regions due to systemic inequities in water, sanitation, and healthcare access. This cross-sectional study assessed the prevalence and risk factors of NTDs among 1,000 participants (600 children above 15 years and 400 women aged 15–49) in rural Liberia using stratified and cluster sampling. Laboratory diagnostics, including Kato-Katz stool analysis, urine filtration, …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 1–7 Read article
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Exploring the Synergy of High Performance Composite Concrete Strength and Sustainable Construction Practice
Abstract: This research evaluates how the combination of industrial waste materials optimizes composite concrete structure strength and services the interests of sustainable construction development. This research examines two major environmental problems stemming from ordinary Portland cement clinker manufacturing and landfill accumulation of non-biodegradable porcelain waste. The research employed alccofine dosage of 16% as a supplementary cementitious material (SCM) with high pozzolanic activity to combat these problems. Processed porcelain waste aggregates filled …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 47–58 Read article
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Environmental and Sanitation Challenges and Their Role in Malaria Transmission: A Case Study of Duport Road Community, Paynesville City, Liberia
Abstract: Introduction: Environmental sanitation plays a crucial role in controlling malaria transmission, yet several factors continue to impede its effectiveness, particularly in communities with poor waste management and drainage systems. This study explores the factors that hinder proper environmental sanitation and their association with the spread of malaria among residents of Duport Road Community, Paynesville City, Liberia. Methods: A descriptive cross-sectional study was conducted, gathering data from 400 participants—both men and …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 2, 2025 · pp. 24–29 Read article
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COVID-19 Resurgence in 2025: India’s Continuing Public Health Challenge
Abstract: The year 2025 has witnessed the resurgence of COVID-19, reigniting concerns at both global and national levels regarding the persistent threat posed by SARS-CoV-2. In early 2025, India witnessed a moderate resurgence of COVID‑19, characterized by the emergence of Omicron sub-variants and a rise in mild-to-moderate infections. As of mid-June, active COVID‑19 cases in India totaled approximately 6,000–7,400, with hotspots in Kerala (~2,100 cases), Delhi (~600), Maharashtra (~500), and several …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 2, 2025 · pp. 16–23 Read article
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Mechanical Analysis and Advanced Manufacturing of Eco-Friendly Groundnut Shell Powder Reinforced Epoxy Composites
Abstract: Polymer composites reinforced with natural materials are gaining significant attention because of their eco-friendly nature, cost-effectiveness, and favorable mechanical properties. This research explores the creation and mechanical analysis of epoxy composites strengthened with groundnut shell powder (GSP), exploring both untreated and benzoyl chloride-treated GSP variations. The research emphasizes utilizing agricultural waste material while achieving enhanced mechanical properties through surface modification and advanced fabrication techniques. The composites were manufactured using the …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 174–185 Read article
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Investigation of Mechanical Properties of Hollow Bricks Incorporating Aerated Aggregates: A Polymer-Cement Composite Approach
Abstract: The rapid advancement of construction technologies has necessitated the development of lightweight, thermally efficient, and sustainable building materials. Hollow bricks, due to their inherent voids, offer substantial reductions in dead load and enhanced insulation properties. However, their mechanical performance often falls short when compared to conventional solid bricks. To address this limitation, this study explores the synergistic integration of aerated aggregates and polymer-cement composites (PCCs) in hollow brick production. Aerated …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 92–105 Read article
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Sustainable Concrete Solutions: Chemically Predictive Modeling of Geopolymer Versus Ordinary Concrete in a Circular Economy
Abstract: Concrete is a fundamental structural material widely used in civil engineering projects. It plays a key role in various types of building structures, with its quality directly influencing the durability of the construction. This research focuses on assessing the current state of concrete construction, highlighting critical issues and technical aspects in the process, while emphasizing the importance of improving construction quality and management practices. Geopolymer concrete (GPC) presents a viable …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 170–192 Read article
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Durability Assessment of Geopolymer and OPC Concretes under Chloride and Sulphate Chemical Attack
Abstract: The main problems with durable concrete constructions are attacks by sulphates and chlorides on concrete. The primary objective of this study is to evaluate how the strength properties of concrete are affected by the incorporation of fly ash when exposed to environmental conditions involving sulphate and chloride solutions. In this research, geopolymer concrete (GPC) is utilized as a replacement for conventional ordinary Portland cement (OPC). The concrete composition is prepared …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 202–218 Read article
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Dynamic Mechanical Analysis of Carbon Fiber Reinforced Polymer Composites
Abstract: This study investigates the thermal decomposition and mechanical properties of Fiber-Reinforced Polymer Composites (FRPCs) using Dynamic Mechanical Analysis (DMA). The research focuses on improving the recycling and recovery process of Carbon Fiber-Reinforced Polymers (CFRPs), addressing environmental concerns regarding their disposal. By analyzing the effects of different heating rates (5°C and 10°C per minute) and atmospheric conditions (nitrogen, oxygen, and a combination of both), the study identifies optimal parameters for maximizing …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 386–393 Read article
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Polymer Chemistry-Driven Design of a Severable Dental Prophylaxis Instrument: Leveraging PEEK and Composites for Enhanced Functionality
Abstract: Polymer chemistry unlocks new possibilities for dental prophylaxis instruments by leveraging molecular design for enhanced functionality. This study explores Polyether Ether Ketone (PEEK), a semi-crystalline thermoplastic, in a novel instrument with a severable working end, featuring a tubular structure with internal screw threads (0.5–0.8 cm) anchoring replaceable elements via a threaded mechanism. PEEK’s aromatic backbone, alternating ether and ketone groups, yields a tensile strength of ~100 MPa, chemical inertness against …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 869–877 Read article
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Polymer Chemistry in Nutraceutical Composites: Exploring Natural Polymers and Binding Systems in a Bamboo-Enhanced Formulation
Abstract: Polymer chemistry underpins the development of advanced nutraceutical composites, blending natural polymers with functional ingredients for health benefits. This study examines a novel nutraceutical formulation comprising ragi (16.39 g/100g), wheat (12.29 g/100g), soybean (12.29 g/100g), buffalo milk (16.39 g/100g), buffalo butter (4.13 g/100g), bamboo extract (0.90 g/100g), and auxiliary components (37.61 g/100g, including fats, sugars, and proteins). Natural polymers—proteins from soybean and milk, polysaccharides from ragi and wheat—form a macromolecular …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 878–884 Read article
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Molecular Docking Analysis of Berberis aristata Phytocompounds as Potential Growth Factor Receptor Blockers in Cancer Therapy
Abstract: Middle-aged and older women are susceptible to breast cancer (BC), a potentially fatal condition. When breast cancer is diagnosed, the median age is 62. Breast cancer diagnoses in women under 45 are comparatively uncommon, whereas the bulk of breast cancer diagnoses occur in women 62 and older. Growth factor receptors are interesting therapeutic targets because of their critical role in the pathophysiology of cancer. Vascular endothelial growth factor receptors (VEGFR-2) …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 1–10 Read article
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Exploring Oroxylum indicum Phytochemicals as VEGFR-2 Inhibitors: A Molecular Docking Approach for Cancer Management
Abstract: Cancer is still a major health problem around the world and is one of the top causes of death. A protein called VEGFR-2 (vascular endothelial growth factor receptor 2) is important because it helps blood vessels grow by supporting the survival, movement, and growth of certain cells. This process is essential for tumors to grow and spread to other parts of the body. This study focused on evaluating the binding …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 48–62 Read article
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Molecular Docking Studies of Nyctanthes arbor-tristis Phytochemicals for Targeting TNF Receptor in Arthritis
Abstract: Rheumatoid Arthritis is an autoimmune disorder which results in inflammation. Tumor necrosis factor-alpha (TNF-α) is responsible for the progression of inflammatory arthritis by promoting immune cell activation and cytokine release. The present study explores the potential of bioactive compounds derived from Nyctanthes arbor-tristis (Parijat) in modulating TNF receptor activity through molecular docking. Computational methods were employed to evaluate the binding affinity of selected phytocompounds from N. arbor-tristis against the extracellular …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 11–21 Read article
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Hybrid Material Systems for Flexible Electronics Electro-Mechanical Performance and Future Prospects
Abstract: Flexible electronics are transforming the landscape of modern electronic systems, enabling devices that are lightweight, stretchable, and adaptable to complex surfaces. These technologies are particularly impactful in applications such as wearable health monitors, soft robotics, energy harvesting systems, and implantable biomedical devices. At the heart of this evolution are hybrid material systems—engineered composites that combine organic polymers and inorganic nanomaterials to achieve synergistic electro-mechanical properties. These materials address the limitations …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 3, Issue 1, 2025 · pp. 7–12 Read article