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1348 articles for “Bars”
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Advancing Cancer Vaccine Development through CRISPR/Cas9 Technologies and Future Opportunities
Abstract: The advent of CRISPR/Cas9 genome editing has revolutionized the cancer immunotherapy market, offering unprecedented precision and versatility in the development of next-generation cancer vaccines. This review examines how CRISPR technologies are being integrated into various stages of cancer vaccine development including neoantigen discovery, dendritic cell engineering, cancer cell reprogramming, and tumor microenvironment modulation. In the area of neoantigen discovery, CRISPR enables rapid identification and validation of tumor-specific mutations, thereby supporting …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 Read article
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Innovations in Targeted Drug Discovery for Personalized Medicine
Abstract: Personalized medicine is revolutionizing modern healthcare by custoizing treatment plans to match an individual’s genetic makeup, protein expression, and metabomlic characteristics. Also referred to as precision medicine, this approach seeks to improve therapeutic outcomes, reduce adverse effects, and make efficient use of healthcare resources. The incorporation of various omics technologies—including genomics, proteomics, transcriptomics, metabolomics, and epigenomics—has greatly advanced our ability to understand disease biology and molecular variations specific to each …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 19–41 Read article
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Rethinking Consumer Preferences for Broiler Meat: Addressing Public Concerns for Sustainable Development
Abstract: Broiler meat is a crucial component of global protein consumption, yet its acceptance is often hindered by concerns related to health, animal welfare, environmental sustainability, and consumer perception. This study examines the factors influencing consumer preferences for broiler meat and explores strategies to address public concerns while promoting sustainable development. Misinformation regarding antibiotic residues, growth promoters, and broiler welfare has contributed to negative consumer sentiment, leading to a preference for …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 2, 2025 Read article
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Drug Screening Using Stem Cell Technology
Abstract: Stem cell technology in drug screening has transformed the research and development sector of pharmaceuticals. Although stem cells imitate their human counterparts in terms of both safety and potential, it is a new paradigm for mimicking diseases of humans and scale measuring for toxicity. These tissues will, therefore, be more predictive of what will happen in humans during clinical situations, compared to conventional cell lines or animal models, since they …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 42–51 Read article
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Beyond Generalized Treatment: The Future is Personalized Medicine
Abstract: Personalized medicine, which is also called as precision medicine, is reestablishing the view of new healthcare by replacing the traditional "one-size-fits-all" approach with individual therapies made according to a patients unique genomic organization, environment, and lifestyle. This article talks about the scientific foundation, important applications, ethical challenges, and the significant potential of personalized medicine in enhancing the clinical outcomes. From oncogenic and genetic disorders to chronic diseases, the addition of …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 2, 2025 Read article
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Phyto-Entrapped Carbon Dots as Emerging Nanomaterials for Anti-Cancer Activity
Abstract: Phytoconstituent-loaded carbon dots (C-dots) represent an innovative approach in targeted cancer therapy, combining the therapeutic power of plant-derived compounds with the advanced capabilities of nanotechnology. These ultra-small, biocompatible nanostructures offer excellent fluorescence, tunable surface chemistry, and low toxicity, making them ideal for drug delivery, bioimaging, and theranostic applications. Traditional phytochemicals often face challenges like poor solubility, low bioavailability, and high first-pass metabolism barriers that C-dots help overcome. C-dots synthesized through …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 51–63 Read article
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Polymer-Nanowire Hybrid Composites Based on PEDOT: PSS and AgNWs for High-Performance Conductive Films in Flexible Devices
Abstract: The growing demand for flexible photovoltaic and wearable optoelectronic devices has intensified research into polymer-based conductive composites that provide transparency, flexibility, and electrical efficiency. In this work, we report the fabrication and characterization of a hybrid polymer nanocomposite electrode comprising silver nanowires (AgNWs) embedded within a PEDOT:PSS matrix, deposited on flexible polyethylene terephthalate (PET) substrates. The PEDOT:PSS polymer phase, modified with 5 vol% dimethyl sulfoxide (DMSO) and 0.1 vol% Zonyl …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 236–250 Read article
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Pharmacogenomics: Unlocking the Genetic Basis of Drug Response for Precision Medicine
Abstract: Pharmacogenomics, a fusion of pharmacology and genomics, explores how genetic variations influence individual responses to medications. This field is revolutionizing modern medicine by moving away from a one-size-fits-all approach toward personalized treatment strategies. By identifying specific genetic markers, pharmacogenomics aims to enhance drug efficacy, minimize adverse drug reactions, and improve overall patient outcomes. Key methodologies in this discipline include candidate gene analysis, genome-wide association studies, and haplotype analysis, all of …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 52–59 Read article
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Physical Activation Process and Characterization of Bioactive Carbon, with a Focus on its Applications
Abstract: Activated carbon is a form of carbon that has been processed to enhance its surface area and porosity. This processing enables it to function as an efficient adsorbent, attracting and retaining other molecules on its surface. In our environment, many types of biomass waste are inexpensive and renewable. Recently, there has been a growing interest in producing products from renewable resources. A prime example is the use of biomass to …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 507–517 Read article
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Advancing Gene Therapy: Next-Generation Viral Vector Engineering for Precision, Safety, and Scalability
Abstract: Gene therapy has emerged as a paradigm-shifting modality for the treatment of genetic disorders, malignancies, and rare diseases through the delivery of therapeutic nucleic acids aimed at correcting or modulating dysfunctional gene expression. Among the various delivery systems, viral vectors including adeno-associated viruses (AAVs), lentiviruses, adenoviruses, retroviruses, and herpes simplex viruses have proven indispensable owing to their high transduction efficiencies and adaptability. This review offers a comprehensive assessment of viral …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 37–55 Read article
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Influence of Static Sequences on the Thermal Behavior of Eco-Friendly Pineapple/Ramie Composites
Abstract: The increasing demand for sustainable and environmentally responsible materials has driven the exploration of natural fiber-reinforced polymer composites as potential alternatives to conventional synthetic materials. Among various natural fibers, pineapple leaf fiber (PALF) and ramie fiber are notable for their complementary characteristics—PALF offers excellent insulating behavior and lightweight structure, while ramie provides high thermal stability and strength. In the field of Eco-friendly composite product manufacturing, the processing temperature holds significant …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 732–742 Read article
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Performance, Emission, and Combustion Evaluation of Chlorella Vulgaris Biodiesel-Diesel Blends in a Compression Ignition Engine
Abstract: This study examines, without modifying the engine, the performance, emissions, and combustion properties of biodiesel blends made from Chlorella vulgaris microalgae in a four-stroke, single-cylinder, water-cooled CI engine. The blends of biodiesel and diesel, designated B10, B20, B30, and B40, were 10%, 20%, 30%, and 40%, respectively. Of these, B20 showed the best efficiency-to-emissions ratio. Although it recorded the lowest brake specific fuel consumption of 0.232 kg/kWh, indicating superior fuel …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 339–354 Read article
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The Evolution and Future Prospects of Solar Energy in India
Abstract: India has made great strides in incorporating solar energy into its renewable energy framework thanks to its plentiful solar resources. This case study examines the nation's advancements in solar energy development, the challenges it still faces, and its prospects for growth. India has aggressively pushed solar efforts to satisfy expanding energy demands responsibly and lessen reliance on fossil fuels, thanks to the country's high levels of sun irradiation in most …
Published in Journal of Energy, Environment & Carbon Credits · Vol. 15, Issue 3, 2025 · pp. 54–59 Read article
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Assessing Knowledge and Awareness of Artificial Intelligence in Academic Research Among Tertiary Students in Ghana
Abstract: Background: While Artificial Intelligence (AI) technologies are evolving rapidly in education, a major deficit in tertiary students' awareness and use of AI-based academic research is observed in Ghana. Prior research notes general awareness but limited use in practice and mentions issues with trust, ethics, and accessibility. Methodology: A cross-sectional survey was undertaken with a sample size of 450 undergraduates and postgraduates from diverse disciplines through stratified random sampling. The study …
Published in Current Trends in Information Technology · Vol. 15, Issue 3, 2025 · pp. 19–25 Read article
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Gesture Vocalizer Using Arduino
Abstract: Science and technology have been an indispensable part of our lives, driving innovation and transforming the way we communicate. Communication barriers between the hearing-impaired and the hearing population pose significant challenges in daily interactions. Sign language, a primary mode of communication for the deaf and mute communities, is not universally understood by the general public. This research work presents a novel system for real-time sign language to speech conversion, aiming …
Published in Journal of Communication Engineering & Systems · Vol. 15, Issue 3, 2025 · pp. 14–25 Read article
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Effective Use of Library Resources and Services by the End Users at PPSavani University, Surat
Abstract: This qualitative research study examines the perceptions of students and faculty regarding the utilization of library resources and services at P. P. Savani University (PPSU), Surat. While the library has modern infrastructure, an extensive print collection (25,000+ books) and digital collection (64,200+ e-journals, 18,500+ e-books), and full automation via KOHA (a widely used open-source Integrated Library System (ILS)), a nuanced understanding of user experiences is paramount to truly optimize its …
Published in Journal of Advancements in Library Sciences · Vol. 12, Issue 3, 2025 · pp. 33–38 Read article
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Smallest Linking Routes and ICT: Enabling Seamless Navigation and Digital Health Access
Abstract: The paper involves around the basic concept of navigation. In this we are trying to add some linking places in between the source and the destination so as to map a new and different navigated route and provide it to the user for additional beneficial use. Healthcare has undergone significant digital transformations driven by the widespread adoption of information and communication technologies (ICT). Many individuals remain unable to access healthcare …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 3, 2024 · pp. 31–38 Read article
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Chewable Healthcare: The Rising Impact of Gummy Supplements in Modern Medicine
Abstract: Gummy supplements, a chewable dosage form historically associated with pediatric vitamin products, are increasingly recognized as a versatile platform for delivering a wide range of nutraceutical and pharmaceutical agents. Their consumer appeal lies in their palatability, convenience, and the ability to overcome swallowing difficulties—a significant barrier to adherence in multiple patient populations. Recent advances in formulation science have expanded the potential of gummy supplements beyond basic vitamin delivery to include …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 52–68 Read article
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Revolutionizing Artificial Organs: Next-Generation Membrane Technologies for Precision Medicine and Global Health
Abstract: Membrane technology has emerged as a cornerstone in the advancement of artificial organ systems, offering critical functionalities in selective molecular filtration, tissue scaffolding, and controlled therapeutic delivery. Recent innovations have propelled the field beyond traditional polymeric membranes to include nanostructured, biomimetic, and stimuli-responsive materials, significantly enhancing biocompatibility, selectivity, and durability. The integration of smart technologies, such as AI-driven membrane design, bioelectronic sensors, and personalized fabrication via 3D printing, is ushering …
Published in International Journal of Membranes · Vol. 2, Issue 2, 2025 · pp. 29–39 Read article
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Graphs and Their Real-Life Applications in Pharmaceutical Research
Abstract: This study provides a comprehensive overview of the role of graphs in pharmacy research, emphasizing their significance as powerful tools for data visualization, interpretation, and communication. In the field of pharmacy, research often generates large volumes of complex data related to drug development, pharmacokinetics, pharmacodynamics, medication safety, and patient outcomes. Graphs serve as an essential medium to translate these data into accessible, interpretable, and actionable insights, supporting evidence-based practice and …
Published in Research & Reviews : Journal of Statistics · Vol. 14, Issue 3, 2025 · pp. 01–08 Read article