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1972 articles for “4-dioxopyrimidine-5-carbonitrile” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Gossypetin Inhibits ROS Generation in HeLa and HepG2 Cell Lines
Abstract: Antioxidants are known for their ability to neutralize the reactive oxygen species present within the living system. These antioxidants are mainly secondary metabolites present in plant products and are generally known as nutraceuticals or bioactive compounds. Antioxidant can be categorized into many categories based upon their structure and activities like flavonoids, anthrocyanins and carotenoids. Flavonoids are heterogeneous polyphenolic compounds having beneficiary effect on human body and are also known to …
Published in Research and Reviews: A Journal of Toxicology · Vol. 7, Issue 1, 2017 · pp. 25–31 Read article
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Cytotoxic, Anthalmintic and Analgesic Activities of the Methanol Extract of Ricinus communis (Family: Euphorbiaceae)
Abstract: The aim of this study was to evaluate the phytochemical screening, cytotoxicity, anthelmintic activity and analgesic properties of the methanol extract (leaves) of Ricinus communis (Family: Euphorbiaceae). The methanol extract of the leaves showed mild cytotoxic activity with the LC50 value 6.456 µg/mL compared to vincristine sulfate (LC50 0.812 µg/mL) using brine shrimp lethality bioassay. The anthelmintic activity was performed by observing the time of paralysis and the time of …
Published in Research and Reviews: A Journal of Toxicology · Vol. 5, Issue 1, 2015 · pp. 27–35 Read article
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Pattern of Poisoning, Management and Antidote Availability in St. Paulo’s Specialized Hospital Addis Ababa, Ethiopia
Abstract: Poisoning is the contact with a substance that results in toxicity. It can be deliberate or accidental. Antidotes are substances opposing the harmful effect of poisons and are cornerstones in the management of poisoning. Availability of antidotes highly affects the effective poisoning management. To assess the poisoning management in relation to an antidote availability. A retrospective study was used to assess the practice of poisoning management and antidote availability in …
Published in Research and Reviews: A Journal of Toxicology · Vol. 5, Issue 3, 2015 · pp. 8–12 Read article
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Statistical Study on Self-Medication and Drug use Pattern in Urban and Rural Areas of Nashik, Maharashtra
Abstract: Self-medication methodology involves taking medications without a doctor's supervision or on their basis or others advice. Self-medication and the use of over-the-counter medications are serious public health concerns worldwide. The study aimed to evaluate self-medication and drug use patterns among urban and rural populations based on their knowledge in Nashik. A descriptive cross-sectional and questionnaire-based study with the prevalence of self-medication and drug use patterns was conducted among 500 people …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 3, 2020 · pp. 29–40 Read article
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The Utilization of Seriwastes (Excreta of Silkworm Larvae, Litter of mulberry leaves in rearing bed, dead larvae and dead pupae of Silkworm) for Biomass and Protein Contents of Black Soldier Fly (BSF), Hermetia illucens (L).
Abstract: AbstractAttempt deals with rearing of Black Soldier Fly (BSF), Hermetia illucens (L) reared on Excreta of Silkworm Larvae, Litter of mulberry leaves in rearing bed, dead larvae and dead pupae of Silkworm. The larval weight of BSF of the control group (Reared on Poultry Feed), first group (reared on Excreta of Silkworm), second group (reared on Litter of mulberry leaves in rearing bed of Silkworm Larvae), third group (reared on …
Published in Research and Reviews: A Journal of Toxicology · Vol. 12, Issue 3, 2022 · pp. 7–17 Read article
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Design and Simulation of Triple Band Microstrip Patch Antenna for Ku-band, K-band and Ka-band Applications
Abstract: AbstractThis paper represents a microstrip patch antenna for future 5G-communication technology. The proposed antenna designs are simulated and their performances are analyzed for different parameters like lower return losses, higher gain, voltage standing wave ratio (VSWR), current distribution, far field radiation and wide bandwidth performance for the tri-frequency band operation in Ku band (12–18 GHz),K-band (18–27 GHz) and Ka-band (27–40 GHz) as per the specified IEEE standard. The proposed antenna …
Published in Journal of Telecommunication, Switching Systems and Networks · Vol. 7, Issue 1, 2020 · pp. 26–33 Read article
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Hybrid Agro-Waste Reinforced PLA Smart Composites with Embedded NFC for Sustainable Lifecycle Monitoring
Abstract: The growing demand for sustainable engineering materials has accelerated the development of biodegradable polymer composites capable of combining structural performance with intelligent lifecycle management. In this study, a smart biodegradable agro-waste polymer composite reinforced with rice husk and sugarcane bagasse fibres was developed using a polylactic acid (PLA) matrix integrated with an embedded passive Near Field Communication (NFC) tag for digital traceability and circular economy applications. The composite containing 80 …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 Read article
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Mechanical Characterization of Untreated Banana Fiber Reinforced PLA Bio-Composites Manufactured by 3D Printing
Abstract: This study investigates the development and mechanical characterization of fused deposition modeling (FDM) filaments utilizing polylactic acid (PLA) reinforced with untreated banana fibers (BF). To address the brittleness of pure PLA and valorize agricultural waste, composite filaments with fiber loadings of 0, 1, 3, and 5 wt.% were fabricated using a single-screw extruder. A Taguchi L16 orthogonal array was employed to optimize printing parameters, including fiber percentage, raster angle, infill …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 Read article
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A Pre-Experimental Study to Evaluate the Effectiveness of a Self-Instructional Module on Knowledge Regarding Breast Self-Examination Among Adolescent Girls in Selected Higher Secondary Schools of Moradabad, Uttar Pradesh
Abstract: Breast cancer remains the most frequently diagnosed cancer among women worldwide and is a major cause of death, with its incidence steadily rising in India. Detecting the disease at an early stage greatly enhances survival rates; however, many cases are identified late due to limited awareness and inadequate access to healthcare resources. Breast self-examination (BSE) is an easy, cost-effective practice that enables women to notice early changes in their breasts. …
Published in International Journal of Oncological Nursing and Practices · Vol. 4, Issue 1, 2026 · pp. 30–36 Read article
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Wind Pressure Analysis on the Selected Structure Using IS 875 (Part 3) 2015 and CFD (Computational Fluid Dynamics)
Abstract: Wind-induced pressure plays a significant role in the safety and serviceability of tall buildings, slender vertical structures, and signboard hoardings. Currently, computational fluid dynamics (CFD) has become an effective supplemental tool in the analysis of the interaction of wind and structures. This paper presents a unified comparative study integrating multiple investigations various modal (ⅰ) Tall rectangular building (50 m × 50 m × 150 m), (ⅱ) Rectangular Building (18 m …
Published in Journal of Offshore Structure and Technology · Vol. 13, Issue 2, 2026 · pp. 70–80 Read article
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A Study to Assess the Add-on Impact of Ayurvedic Management along with Ongoing Conventional Treatment of Diabetes Mellitus: A Randomized Clinical Trial
Abstract: Diabetes affects millions and thus is a major public health disease among with adults aged 30+. Available treatment although helps but many develop other side effects to complicate the issue. Ayurveda offers options to manage diabetes without complications. Present study is to see the add-on effect of Ayurveda therapy among persons on modern medicines. Ayurveda D4 combination is Jamunbeej and Gudmarpatra 5 gm churna each before breakfast and dinner and …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy Read article
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Study of Behavior of Buckling Restrained Bearing Frame Along with Soil Structure Interaction
Abstract: Lateral forces due to earthquake are the major consideration for design of earthquake resisting structures, these forces can be resisted by various systems like braced frames, shear walls, moment frames, etc. Energy dissipation is one of the most convenient option for earthquake resistance, as it can absorb input energy from earthquake protecting the main structure. Past research revealed that the Buckling Restrained Braces (BRB) are the best type of energy …
Published in Journal of Construction Engineering, Technology & Management Read article
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Mechanical Performance Degradation of Naturally Aged Nitrile Butadiene Rubber in Low Frequency Range...
Abstract: For good mechanical design, damping is often still an invisible requirement. Nitrile Butadiene Rubber (NBR) has a wide range of applications as a damping and sealing material. To offer the long-term service of NBR, it is important to estimate the degradation of modal properties under complex mechanical and environmental loading. The present work aims to correlate the experimental data with generalized higher-order Maxwell models and curve fitting techniques to find …
Published in Journal of Polymer & Composites Read article
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Studies on Mechanical, Optical, Barrier Properties and Characterization of LDPE-PLA Blend Films with Micro Clay
Abstract: Low density poly ethylene (LDPE) and Poly lactic acid (PLA) in the ratio of 70:30 wt% were blended along with ethylene glycidyl meth acrylate (EGMA) as compatibilizer (2.5%), benzophenone as photodegradable additive (1%) and microclay (1,3,5%) as filler. Blending took place in a twin-screw extruder and then the resulting blend was processed into a film using blown film extrusion. Mechanical, optical, barrier and degradative properties of film were tested as …
Published in Journal of Polymer & Composites Read article
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An Effective Role of Soil Minerals in Plant Nutrition
Abstract: Soil mineral nutrient required by plants is an essential for its survival without availability it can’t be survived. A various way of transportation of nutrients through different phenomenon’s involved in its activity. Although, 17 essential elements are required by plants in which Carbon, Hydrogen and Oxygen is freely available in the atmosphere whereas other nutrients are available through soil. Uptake of nutrients by plants in ionic (both cationic and anionic) …
Published in Research and Reviews : Journal of Crop science and Technology Read article
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Assessment of Effective use of Online Webinars, Workshop, Conference and Quizzes on Library Science Professionals during Covid Scenario: A Survey
Abstract: Due Covid-19 virus around the globe all sectors have been jeopardized and came to halt. Libraries were not exceptions too, where library professionals started learning and sharing professional knowledge through different e-platforms on different Library Science themes, issues and challenges after a covid scenario in the libraries. The study explored the library science professionals on effective use of online webinars and other series during covid times. The study employed quantitative …
Published in Journal of Advancements in Library Sciences Read article
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Phase Behaviour Study of a Mesogen in a Solvent Role of Molecular Rigidity and Configurational Entropy
Abstract: The phase behaviour of a nematogen 4’-n-pentyloxy-4-biphenylcarbonitrile (POBPCB) has been studied with respect to the translational and orientational motions. The charges of atoms and their dipole moments have been estimated by implementing the complete neglect differential overlap (CNDO/2) method. The long-range interactions have been analyzed using modified Rayleigh- Schrodinger Perturbation theory together with the multicentred-multipole expansion scheme. The “6- exp” potential function has been considered to study the short-range interactions. …
Published in Research & Reviews : Journal of Physics Read article
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Synergistic and Antagonistic Effects of Azo-Schiff Base with Some Antibiotics on Gram-Positive Bacterial Isolates
Abstract: Antibacterial resistance has brought an urgent need to find a solution to the problem of antibacterial resistance and increase the effectiveness of antibiotics. Therefore, our current study was aimed to test the three concentrations viz., 0.5 mg/ml, 5 mg/ml and 50 mg/ml of Azo-Schiff base against Grampositive bacteria—Bacillus cereus, Micrococcus lutes, Staphylococcus aureus—to compare the effects of Schiff base alone or along with antibiotics on the viability of bacteria. Our …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 11, Issue 2, 2021 · pp. 25–31 Read article
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HPLC and Tandem MS Device for the Recognition of Emtricitabine and Tenofovir Alafenamide in K2EDTA Human Plasma Utilizing Emtricitabine 15ND2 Tenofovir D5 as an IS
Abstract: Developed very impressionable, discriminating, and exact extreme-efficiency liquid chromatographytandem bulk spectrometry form for measurement of Emtricitabine and Tenofovir Alafenamide in human plasma. Emtricitabine15ND2 Tenofovir D5 was used as a within the standard (IS). The samples were divided on Phenomenex Kinetex C18 5 μm 100A, 100*4.6 mm procession utilizing Acetonitrile: 0.2% formic acid, 60:40 V/V as movable state, the retention period of Emtricitabine: 1.36 minutes (±0.5 minutes), Emtricitabine 15ND2: 1.36 minutes …
Published in Research and Reviews: A Journal of Toxicology Read article
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Hydroxybowdichione Flavonoids As Inhibitors of Dengue Virus Ns5 RNA-Dependent RNA Polymerase Using Molecular Docking Approach
Abstract: Objectives: Human lives are now seriously threatened by dengue fever, which is brought on by the dengue virus (DENV). Aedes aegypti mosquitoes, which reproduce in still water, are the primary vectors of the arboviral virus known as dengue. It is well-recognized that phytochemicals have a high potential to eliminate bacterial, viral, and fungal infections in people. Thus, it demonstrates its inhibitory effects on the dengue virus. This study identifies some …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 1, 2023 · pp. 1–16 Read article