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389 articles for “optimization function”
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Pharmacokinetics of Levothyroxine and Factors Influencing Its Therapeutic Efficacy in Hypothyroidism: A Comprehensive Review
Abstract: Levothyroxine (LT4) remains the standard therapy for hypothyroidism due to its effectiveness in restoring normal thyroid hormone levels and improving physiological functions. However, its pharmacokinetic profile exhibits considerable variability, which may influence therapeutic outcomes in clinical practice. This review aims to comprehensively evaluate the pharmacokinetics of levothyroxine, including its absorption, distribution, metabolism, and elimination, along with factors affecting its therapeutic efficacy. A structured literature search was conducted using electronic databases, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 Read article
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The Impact of Nutrition on Sports Performance and Academic Success: A Study Among University Athletes – Eastern Technical University of Sierra Leone
Abstract: University athletes operate within dual-performance environments that require simultaneous academic and athletic excellence. Nutrition plays a critical role in supporting both physiological performance and cognitive functioning; however, limited empirical work has examined its combined influence on athletic and academic outcomes within university athlete populations, particularly in low-resource contexts. This study aimed to investigate the relationship between nutritional practices, sports performance, and academic achievement among university athletes at the Eastern Technical …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 15, Issue 1, 2026 · pp. 16–27 Read article
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AutoGen Bike: A Self-Sustaining Smart Electric Bike with Integrated AI Safety Systems
Abstract: This is the paper which gives the information about the self-sustaining electric bike. This also tells the idea about how energy is produced during its usage. The “Auto gen bike” is the most useful aspect that can change the future of the electric bikes. This also helps in the conservation of natural resources and nature. This also helps in the accidents happening to the two-wheel vehicle. This is achieved by …
Published in Journal of Automobile Engineering and Applications · Vol. 12, Issue 2, 2025 · pp. 41–49 Read article
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Molecular Transport Kinetics of Non-Polar Solvents Through AGNP Filled EPDM Elastomeric Composites
Abstract: EPDM Based rubber composites can be used in tank and pipe lining works. In these applications one of the major requirements is that the composite must have good fluid permeability and chemical degradation resistances in their working environment. In order to enhance the performance of EPDM rubber to suit these applications, scientists and engineers are trying to develop novel nanocomposites by incorporating nano fillers. In the present work, to ensure …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 993–1006 Read article
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AI-Driven Inverse Design of Functionally Graded Bio-Nanocomposites for Sustainable High-Barrier Packaging
Abstract: Multilayer plastic packaging realizes high barrier performance through laminated heterogeneous structures, but the heterogeneous structure has severe end-of-life challenges caused by the interfacial incompatibility of materials and the poor recyclability. This study proposes the inverse design of functionally graded PLA-nanoclay composite films by reinforcement learning as a monolithic alternative to traditional multilayer systems. Twin-screw extrusion is designed as a continuous control Markov decision process, and proximal policy optimization (PPO) is …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1547–1564 Read article
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LQR-Based Optimal Control of Inverted Pendulum System with State Estimation and Stability Analysis
Abstract: The inverted pendulum on a cart is a canonical benchmark problem in control systems engineering, capturing the essential challenges of stabilizing an inherently unstable, underactuated, and nonlinear plant. Classical Proportional-Integral-Derivative (PID) controllers, while widely employed in industrial practice, exhibit fundamental performance limitations when applied to such systems, primarily due to their inability to account for multivariable coupling, process noise, and the absence of a systematic optimization framework. This paper presents …
Published in International Journal of Advanced Control and System Engineering · Vol. 4, Issue 1, 2026 · pp. 31–43 Read article
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AI-Driven Framework for Accelerating Polymer Nanocomposite Commercialization in Computational Materials Engineering
Abstract: The remarkable mechanical strength increased functional qualities, lightweight structure, and thermal stability of polymer nanocomposites have prompted modern materials research to prioritize their rapid commercialization. Advanced materials can be created by adding nanoscale fillers such as carbon nanotubes, graphene, silica, and metal oxides to polymer matrices. These materials have applications in biomedical engineering, aerospace, electronics, packaging, and automobile manufacture. Research and development of polymer nanocomposites has traditionally relied on costly …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 1–19 Read article
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A Review Article on Nutraceuticals – An Impact on Conventional Health Care
Abstract: Nutraceuticals, combining nutrition and pharmaceuticals, have transformed healthcare. This review explores their classification, scope, benefits, and challenges. Nutraceuticals, including dietary supplements, functional foods, herbal products, and fortified foods, promote health and prevent diseases. The global market, valued at $117 billion, is expanding rapidly, fueled by the growing focus on health. Key benefits are boosted health benefits, fewer side effects, natural options improved nutrition. Classification is traditional (conventional) nutraceuticals (e.g., lycopene, …
Published in International Journal of Nutritions · Vol. 2, Issue 1, 2025 · pp. 9–23 Read article
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Next-Generation Biodegradable Polymer Composites: Enhancing Mechanical and Thermal Performance through Green Reinforcements
Abstract: Next-generation biodegradable polymer composites, combining compostable matrices such as polylactic acid (PLA), polyhydroxyalkanoates (PHAs) and starch-based polymers with green reinforcements (e.g., nanocellulose, lignin, agricultural residues and other bio-fillers), offer a pragmatic route to reconcile high performance with end-of-life sustainability. This paper examines recent advances in the design, processing and interfacial engineering of such composites to enhance mechanical stiffness, strength, toughness and thermal stability while preserving—or intentionally controlling—biodegradation pathways. Emphasis is …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1780–1794 Read article
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The Use of Autologous Platelet-Rich Plasma in Treating Web Space Scar Contractures in Pediatric Burn Patients
Abstract: Burn injuries are prevalent among children, with scald injuries emerging as the predominant type among those under the age of five, constituting more than 65% of cases. Despite receiving appropriate initial treatment and compressive therapy, deep burns often result in contractures, with web space and hand contractures being the most frequent and functionally limiting.To address these challenges in burn management, Autologous Platelet Rich Plasma (APRP) has emerged as a significant …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 1, 2024 · pp. 1–5 Read article
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Optimizing Sampling Techniques Using Fuzzy Set Theory: A Comprehensive Approach
Abstract: Sampling is a critical process in statistics, used to estimate population parameters without needing to examine the entire population. Traditional sampling methods, such as simple random sampling, stratified sampling, and cluster sampling, face limitations when applied to complex or heterogeneous populations with imprecise boundaries. These methods often fail to accurately represent populations with overlapping characteristics or missing data, resulting in sampling bias and reduced accuracy. To address these challenges, this …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 12, Issue 1, 2025 · pp. 29–43 Read article
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Inverse Model for Predicting Thermal Abnormality of the Transient Process Triggered by Defective Electronics Element
Abstract: The paper presents a model for predicting thermal abnormalities in Printed Circuit Boards (PCBs) by approximating the thermal process of electric elements with heating from point sources. Circuit board heat sources are defined as point and non-point. The point heat source is a small electronic heating element that can be approximated as having originated from one point on the circuit board. A non-point source is one with heat distributed over …
Published in International Journal of Energy and Thermal Applications · Vol. 3, Issue 2, 2025 · pp. 24–31 Read article
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FEA Simulation for Optimization of Laminated Composite Plate with Cutout in Free Vibrations
Abstract: Laminated composites have a large application in engineering. The work done in this study is to see the free vibration response of graphite epoxy composite square plate subjected to different boundary conditions. Finite element analysis has been done on the software ANSYS. The results obtained by the simulation have been compared with those obtained from a published data obtained by semianalytical solution. It is observed that the solutions through ANSYS …
Published in Journal of Experimental & Applied Mechanics Read article
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Fabrication of Belt for Backpack for Students to Reduce the Musculoskeletal Disorders using ABS material 3D Printing
Abstract: In the present study, the design and development of a composite-based belt aim to reduce the excessive burden on the backs of schoolchildren, which often leads to musculoskeletal disorders (MSD). The belt is designed using CATIA 3D modeling software and fabricated on an FDM-based 3D printer with ABS polymer. The design process focuses on addressing physical stress caused by heavy backpacks and prolonged use of electronic devices, both of which …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 1110–1117 Read article
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Studies on the antioxidant content and antimicrobial activity of cucumber (cucumissativus) peel collected from bagmari, kolkata, west bengal, india
Abstract: Cucumber (Cucumis sativus) is widely consumed across the globe, yet its peels are commonly discarded as waste, despite possessing a wealth of bioactive compounds. Recent studies have highlighted that these peels contain substantial amounts of antioxidants, antibacterial, anti-inflammatory, and anti-carcinogenic properties, making them a promising candidate for value-added applications. In this study, methanolic extracts (80% v/v) of cucumber peels were systematically analyzed to assess their total phenolic content (TPC), total …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 2, 2025 Read article
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The Emergence of Personal Desktop Voice Assistants for Effortless Task Management
Abstract: In an era defined by rapid technological advancement, desktop voice assistants have emerged as crucial tools, not only for enhancing productivity but also for fundamentally reshaping digital interactions. This study delves into the transformative potential of voice-enabled artificial intelligence in task automation, emphasizing its profound impact on efficiency, accessibility, and overall user experience. By harnessing the power of natural language processing and machine learning, these desktop assistants facilitate hands-free operation, …
Published in Journal of Microelectronics and Solid State Devices · Vol. 12, Issue 3, 2025 · pp. 11–16 Read article
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Studies on the Antioxidant Content and Antimicrobial Activity of Cucumber (Cucumis sativus) Peels Collected from Bagmari, Kolkata, West Bengal, India
Abstract: Cucumber (Cucumis sativus) is widely consumed across the globe, yet its peels are commonly discarded as waste, despite possessing a wealth of bioactive compounds. Recent studies have highlighted that these peels contain substantial amounts of antioxidants, antibacterial, anti-inflammatory, and anticarcinogenic properties, making them a promising candidate for value-added applications. In this study, methanolic extracts (80% v/v) of cucumber peels were systematically analyzed to assess their total phenolic content (TPC), total …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 2, 2025 · pp. 6–14 Read article
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Structure–Property Correlation of Infill Topology and Density on Tensile and Flexural Performance of FDM-Printed PLA and ABS
Abstract: Additive Manufacturing (AM), particularly Fused Deposition Modeling (FDM), has become a widely adopted manufacturing technology due to its design flexibility, low cost, and capability for rapid prototyping. However, the mechanical performance of FDM-printed components is strongly influenced by internal structural parameters such as infill pattern and infill density, in addition to the intrinsic material behaviour. This study investigates the structure–property relationship between infill topology, density, and mechanical performance of PLA …
Published in International Journal of Fracture Mechanics and Damage Science · Vol. 4, Issue 1, 2026 · pp. 26–37 Read article
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Effect of Functionalization on glass transition temperature of Carbon Fiber reinforced Epoxy Nanocomposites using MD Simulation
Abstract: As we all know that the mechanical characterization of any material plays a vital role in performance of the material throughout its life cycle. One of the major parameters in calculating the mechanical properties of carbon fiber reinforced nanocomposite is glass temperature. Understanding glass transition behaviour of polymer nanocomposites are crucial for optimizing their mechanical properties and performance. We used “Molecular dynamics simulations” to calculate sequel functionalization effect on glass …
Published in Journal of Polymer & Composites · Vol. 12, Issue 5, 2024 · pp. 1–8 Read article
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Integrating Human-Centric Principles into Machine Design: Ergonomic and Safety Enhancements in Mechanical Systems
Abstract: The integration of human-centric design (HCD) principles into mechanical systems has become increasingly critical in contemporary machine design. As machines become more complex and operate within high-interaction environments, the need for design strategies that prioritize human safety, usability, and comfort has intensified. This review explores how ergonomic insights, safety standards, and user experience (UX) considerations influence the physical configuration, control mechanisms, and operational safety of mechanical systems across industrial, healthcare, …
Published in Trends in Machine design · Vol. 12, Issue 2, 2025 · pp. 33–37 Read article