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269 articles for “Path finding”
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Experimental and Numerical Investigation of Corrosion-Induced Failures in Copper-Tin Alloy (Cu-Sn) and Aluminum-Magnesium Alloy (Al-Mg) Connectors: A Stress–Corrosion Coupling Analysis
Abstract: The utilization of an integrated experimental and finite element modelling (FEM) methodology, this study investigates the degradation and failure mechanisms in polymer composite electrical connectors exposed to aggressive environmental conditions. Epoxy- and polyamide-based composites, reinforced with carbon and glass fibers, were subjected to accelerated salt spray and humidity–temperature cycles to simulate prolonged outdoor exposure. Electrochemical and environmental aging experiments revealed that chloride ions and moisture ingress were responsible for matrix …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 366–379 Read article
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How Scientists Look for New Pathogens Before They Spread
Abstract: Emerging infectious illnesses are a persistent danger to global health. They often come from unexpected places, such wildlife reservoirs, changes in the climate, or human activities. Finding new diseases before they create epidemics is one of the biggest problems in modern epidemiology. This article talks about how scientists use genetic monitoring, field sampling, and real-time data processing to find, track, and describe new infectious organisms in a way that works …
Published in International Journal of Pathogens · Vol. 3, Issue 1, 2026 · pp. 11–17 Read article
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Precision Medicine for Neurofibromatosis Type 1: Progress and Prospects in Drug Discovery
Abstract: Objective: The development of neurofibromas, café-au-lait spots, and other neurological problems are the hallmarks of neurofibromatosis type 1 (NF1), a hereditary disorder. The dearth of efficacious pharmaceutical therapies underscores the need for novel therapeutic approaches, even in the face of clinical variability. Through very accurate prediction of the binding affinity of possible therapeutic drugs with the target protein, the computational technique known as “molecular docking” has become a potent tool …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 01–15 Read article
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Cervical Leiomyomas: Age associated insights from 3 Year prospective study from Tertiary Care Hospital
Abstract: Cervical leiomyomas are rare benign smooth muscle tumours of cervix, often presenting diagnostic challenges due to their uncommon occurrence and overlapping features with other cervical pathologies. This is a 3-year prospective study involving a total of 460 female subjects who were diagnosed with various gynecologic complications, with a particular focus on cervical leiomyomas. The study aims to provide a comprehensive age-wise distribution of cervical leiomyomas, emphasizing the incidence and prevalence …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 Read article
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Molecular Pharmacokinetics and Structural Docking of Phenolic Acids for Targeting NF-κB Pathway Components in Inflammation and Fibrosis: A Computational Approach Toward Therapeutic Discovery
Abstract: Inflammation and Fibrosis are critical pathological processes associated with various chronic diseases, often mediated by the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway. This study investigates the therapeutic potential of phenolic acids as modulators of the NF-κB pathway, aiming to identify novel ligands that can effectively interact with key components of this signaling cascade. A comprehensive computational approach was employed, utilizing molecular docking, pharmacological screening, and post-docking …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 14–31 Read article
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Multifactorial Diseases Becoming the Epigenetic Factor for the Genz
Abstract: This comprehensive paper investigates the complex interplay between multifactorial diseases, particularly obesity and cardiovascular disease (CVD), and their relationship with epigenetic mechanisms, highlighting the transgenerational implications of these interactions. The multifaceted nature of obesity and CVD, involving genetic predisposition, environmental influences, and epigenetic modifications, underscores the intricate pathways contributing to disease susceptibility and progression. Drawing upon a synthesis of diverse research findings, the paper elucidates the critical role of genetic …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 16–22 Read article
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Stiff Person Syndrome: Advances in Understanding, Diagnosis, and Treatment of a Rare Autoimmune Disorder
Abstract: Stiff Person Syndrome (SPS) is a rare and complex autoimmune neurological disorder characterized by progressive muscle stiffness, rigidity, and painful spasms. This chapter provides a comprehensive overview of SPS, exploring its pathophysiology, clinical presentation, diagnostic challenges, and current treatment approaches. We discuss the latest research findings, including the role of autoantibodies, genetic factors, and environmental triggers in the development of SPS. The chapter examines various diagnostic methods, emphasizing the importance …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 35–43 Read article
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Development of Self-Healing Circuit Boards Using Shape Memory Polymer Composites
Abstract: This study investigates the influence of temperature, humidity, and nanofiller type on the electrical and structural performance of advanced polymer nanocomposites for self-healing circuit applications. Particular attention was given to conductivity retention and the morphological behavior of carbon nanotubes (CNTs), graphene, and silver nanoparticles (AgNPs). Results show that conductivity decreased under elevated thermal–humidity conditions, reflecting the role of environmental stress in material degradation. Among the tested systems, AgNP-based composites achieved …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 746–770 Read article
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Power Supply Design Issues for Personnel Computers Application: A Review
Abstract: A power supply should meet various requirements for proper functioning of a PC. Electromagnetic Interface (EMI) causes catastrophic failures resulting in malfunctioning of PC's. It is therefore essential to meet the Electromagnetic Compatibility (EMC) requirements in addition to other design considerations demanded in a high technology system. The computer is operating and transmitting the signal with low voltage, so it is sensitive to Electromagnetic interference of leakage. Since the PC …
Published in Journal of Power Electronics and Power Systems · Vol. 3, Issue 2, 2013 · pp. 37–40 Read article
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Management of Polycystic Ovarian Syndrome (PCOS)
Abstract: The complex condition known as polycystic ovarian syndrome (PCOS) is characterized by chronic anovulation and hyperandrogenism. Depending on diagnostic criteria, 6–20% of females in reproductive age are afflicted. PCOS symptoms start to appear in the early pubertal years. Acne, anovulation, and irregular menstrual periods are features of PCOS and pubertal development in the average girl. The complex intertwined pathophysiology makes it difficult to identify the provoking factors. Most available scientific …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 11, Issue 2, 2022 · pp. 35–41 Read article
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To Find the Nucleotide and Protein Sequence of AMYLASE in Homo Sapiens in FASTA Format
Abstract: Comprehensive analysis of current enzymes with α-amylase activity (AAMY) belonging to family 13 of glycoside hydrolases (arrangements of 144 archaea, bacteria, and eukaryotes from different species of GH13; 87). Offers. This study aims to deepen our knowledge of the evolutionary molecular relationships between the sequences of the A and B domains, with a particular focus on the correlation between what is observed in structure and the evolution of proteins. A-domain …
Published in Research and Reviews : Journal of Computational Biology · Vol. 10, Issue 3, 2021 · pp. 13–15 Read article
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Green Synthesis of Silver Nanoparticles: Antifungal Efficacy Against Aspergillus niger and Agricultural Benefits
Abstract: Silver nanoparticles (AgNPs) are gaining significant attention in agriculture due to their potent antifungal properties. This study focuses on evaluating the antifungal effects of green synthesized AgNPs derived from Aloe vera leaf extract against the pathogenic fungus Aspergillus niger. The results indicate that the synthesized nanoparticles exhibited a strong absorption maximum at 550 nm, indicative of surface plasmon resonance. UV-Vis spectroscopy was used to analyze the nanoparticles, and the solution …
Published in International Journal of Fungi · Vol. 1, Issue 1, 2024 · pp. 19–23 Read article
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Path Guidance for Blind Person using Ultrasonic Sensor
Abstract: AbstractIn this paper, the proposed designed system a user-friendly system for visually disable people which helps visually impared people to detect objects in the path and show the direction for destination. Ultrasonic sensor determines the presence of object in front of the user as it finds any object, it transmits a signal to the microcontroller. It results to the output of buzzer sound. Global system for mobile application is used …
Published in Recent Trends in Electronics Communication Systems · Vol. 4, Issue 3, 2017 · pp. 13–16 Read article
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Development of a Polymeric Detection System for Salivary Annexin-1: A Potential Tool for Point-of-Care Diagnostics in Periodontal Disease
Abstract: Salivary annexin-1, a protein with anti-inflammatory properties, has emerged as a potential biomarker for periodontal disease. However, current detection methods, like ELISA, are often complex and require laboratory settings. This study explores the development of a novel polymeric detection system for the rapid and sensitive identification of salivary annexin-1. This system could leverage the unique properties of polymers to create a point-of-care diagnostic tool for: (1) early detection and monitoring …
Published in Journal of Polymer & Composites · Vol. 12, Issue 5, 2024 · pp. 101–110 Read article
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The Contextual Effect of Vowels on Correct Production of Retroflex in Kannada Speaking Children with Speech Sound Disorder: A Case Study
Abstract: Contextual based interaction of speech sounds, coarticulation, is the main component of intelligible continuous speech. This interaction between speech sounds within and across the words is affected in children with speech sound disorders (SSD). Literature reports on certain contexts facilitating the production of different speech sounds. Thus, these contextual considerations are vital for the selection of target stimuli during articulation therapy for faster learning. As phonotactics and coarticulation are language …
Published in Research and Reviews : Journal of Computational Biology · Vol. 7, Issue 2, 2018 · pp. 46–66 Read article
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Systematic Review on: Peptic Ulcer and Its Management
Abstract: Peptic ulcer disease (PUD), which affects 5–10% of people worldwide, is still a significant global health concern. Gastric acid and pepsin's corrosive effects cause mucosal injury in the stomach, duodenum, or lower oesophagus. Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori infection are the primary reasons. This review's goal is to examine PUD's aetiology, risk factors, pathophysiology, clinical symptoms, diagnostic methods, and evidence-based treatment modalities. PubMed, Google Scholar, …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 1, 2026 Read article
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Systematic Review on: Peptic Ulcer and Its Management
Abstract: Peptic ulcer disease (PUD), which affects 5–10% of people worldwide, is still a significant global health concern. Gastric acid and pepsin's corrosive effects cause mucosal injury in the stomach, duodenum, or lower oesophagus. Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori infection are the primary reasons. This review's goal is to examine PUD's aetiology, risk factors, pathophysiology, clinical symptoms, diagnostic methods, and evidence-based treatment modalities. PubMed, Google Scholar, …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 1, 2026 · pp. 60–64 Read article
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In Silico Exploration of Podophyllum Hexandrum-Derived Phytocompounds as Potential Therapeutics Against Small Cell Lung Cancer (SCLC): A Molecular Docking Approach
Abstract: Small Cell Lung Cancer (SCLC) is a fast-growing and aggressive type of lung cancer that spreads quickly strongly associated with smoking. It is characterized by symptoms, such as persistent cough, breathing difficulties, or hoarseness, though it can sometimes be asymptomatic which makes early detection challenging. The tumor suppressor gene TP53 is critical in regulating the cell cycle and preventing uncontrolled cell division. Mutations in TP53 result in the loss of …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 1–11 Read article
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Interpretation of Position Information Based Routing Protocols with Different Transmission Power
Abstract: VANET is a technology that is used to avoid accident and it provides safety on road. VANET is used to achieve the continuous connectivity. It provides essential alert and accessing comfort and entertainment on road. Routing protocol plays big role in vehicular network. It provide a way how to find so many routes to reach destination and if network failure then it goes to alternate path. Hence this paper proposed …
Published in Journal of Telecommunication, Switching Systems and Networks · Vol. 2, Issue 3, 2015 · pp. 1–5 Read article
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Hybrid Techniques in Mango Leaf Disease Identification: Evaluating Neural Networks and Support Vector Machines
Abstract: Mango leaf diseases pose a significant threat to mango production, impacting both yield and fruit quality. Early and accurate detection of these diseases is crucial for effective management. This paper evaluates the use of hybrid techniques, specifically the integration of neural networks (NNs) and support vector machines (SVM), in the identification and classification of mango leaf diseases. NN excel in extracting complex features from images, while SVMs are robust classifiers, …
Published in Trends in Opto-electro & Optical Communication · Vol. 14, Issue 3, 2024 · pp. 19–27 Read article