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1037 articles for “severity”
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Vaccines in the Fight Against COVID-19: Mechanisms, Efficacy, and Global Challenges
Abstract: The SARS-CoV-2 pandemic has created an unparalleled public health problem, necessitating comprehensive prevention. This page discusses COVID-19's evolution, scientific understanding, and quick vaccine production and implementation. It compares the mechanisms, efficacy, and safety profiles of the four major types of COVID-19 vaccines—namely mRNA, viral vector, protein subunit, and inactivated virus vaccines. Each type is evaluated in terms of how it stimulates the immune response, its effectiveness in preventing infection or …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 34–48 Read article
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Integration of 5G and Low Earth Orbit (LEO) Satellite Communication for Global Connectivity
Abstract: This integration revolutionizes global connectivity by merging 5G's urban capabilities with LEO's wilderness coverage. This research examines how LEO satellite constellations can complement terrestrial 5G networks to extend high-speed, low-latency connectivity to underserved regions including rural areas, oceans, and airspace. Recent breakthroughs in LEO satellite technology and successful demonstrations of 5G-satellite integration point to a rapidly evolving ecosystem with significant market growth potential. To fully realize the potential of advanced …
Published in Journal of Thermal Engineering and Applications · Vol. 12, Issue 2, 2025 · pp. 15–32 Read article
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Design and Structural Evaluation of a Dual-Axle Trailer Frame with a Focus on Increasing Strength While Aiming to Reduce Overall Weight
Abstract: The primary objective of this project is to evaluate various cross-sections and materials for the structural frame. The frame includes elongated side components and a central longitudinal member, which is connected to several cross-supports. The design focuses on optimizing both the cross-support layout and the choice of materials, incorporating composites to enhance performance. Load conditions are also altered to achieve improved efficiency. Static simulations are performed using ANSYS, while CATIA …
Published in Journal of Experimental & Applied Mechanics · Vol. 16, Issue 2, 2025 · pp. 9–17 Read article
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Environmental and Sanitation Challenges and Their Role in Malaria Transmission: A Case Study of Duport Road Community, Paynesville City, Liberia
Abstract: Introduction: Environmental sanitation plays a crucial role in controlling malaria transmission, yet several factors continue to impede its effectiveness, particularly in communities with poor waste management and drainage systems. This study explores the factors that hinder proper environmental sanitation and their association with the spread of malaria among residents of Duport Road Community, Paynesville City, Liberia. Methods: A descriptive cross-sectional study was conducted, gathering data from 400 participants—both men and …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 2, 2025 · pp. 24–29 Read article
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Classification of Plant Leaf Diseases Using Deep Learning Concepts
Abstract: Agriculture is vital to the economy of a country like India, where 70% of the workforce is employed in this sector. Plants suffering from illnesses experience a significant reduction in output. Delays in the identification of plant diseases lead to decreased yield and plant mortality. The cost of manufacturing is increased since it takes a big number of experts to manually detect plant diseases over several acres of land. The …
Published in Journal of Image Processing & Pattern Recognition Progress · Vol. 12, Issue 3, 2025 · pp. 46–55 Read article
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A Comprehensive Study on Rural Housing in India: A Review
Abstract: Rural housing plays a pivotal role in the socio-economic development of India, as it directly influences the quality of life, health, and productivity of rural populations. Despite the launch of several governmental initiatives aimed at addressing rural housing shortages, a substantial segment of the rural population continues to reside in inadequate, unsafe, and non-durable dwellings that lack basic amenities. This paper presents a comprehensive review of the current scenario of …
Published in International Journal of Rural and Regional Development · Vol. 3, Issue 2, 2025 · pp. 30–38 Read article
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Topology and Geometry in Data Science: Persistent Homology and Beyond
Abstract: In recent years, the interplay between topology, geometry, and data science has gained substantial momentum, offering powerful frameworks to analyze and interpret complex datasets. Traditional statistical and machine learning methods often rely on linear or metric- based assumptions, which may fail to capture the intrinsic structure of high-dimensional or nonlinear data. In contrast, topological and geometric methods provide shape-oriented, scale- invariant tools that focus on the continuity, connectivity, and global …
Published in Recent Trends in Mathematics · Vol. 1, Issue 2, 2024 · pp. 21–27 Read article
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The Impact of Geographical Indications on Sustainable Rural Development: Comprehensive Economic and Cultural Insights from Wayanad, Kerala
Abstract: Geographical Indications (GIs) play a vital role in fostering sustainable rural development by linking unique local products to their geographic origins. This study explores the impact of GIs on economic growth, cultural preservation, and environmental sustainability in Wayanad, Kerala. Drawing from extensive secondary data and detailed case studies including Wayanad Coffee, Jeerakasala Rice, and traditional handicrafts, the research highlights how GI certification enhances market value, improves income levels, and preserves …
Published in International Journal of Rural and Regional Development · Vol. 3, Issue 2, 2025 · pp. 18–29 Read article
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A Systematic Review on Leukemia Detection and Classification Techniques Using Gene Expression
Abstract: Early diagnosis of genetic diseases is crucial for effective treatment, especially in the case of Leukemia, a type of blood cancer characterized by abnormal proliferation of white blood cells. This paper presents a systematic review of recent computational techniques for the detection and classification of Leukemia using gene expression data obtained from DNA microarray analysis. The study explores diverse methodologies including machine learning (ML), deep learning (DL), and bio-inspired algorithms …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 Read article
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Advancing Cancer Vaccine Development through CRISPR/Cas9 Technologies and Future Opportunities
Abstract: The advent of CRISPR/Cas9 genome editing has revolutionized the cancer immunotherapy market, offering unprecedented precision and versatility in the development of next-generation cancer vaccines. This review examines how CRISPR technologies are being integrated into various stages of cancer vaccine development including neoantigen discovery, dendritic cell engineering, cancer cell reprogramming, and tumor microenvironment modulation. In the area of neoantigen discovery, CRISPR enables rapid identification and validation of tumor-specific mutations, thereby supporting …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 Read article
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Review article on Quality Control in Clinical Trials
Abstract: Quality control (QC) is a critical component in the conduct of clinical trials, ensuring the accuracy, reliability, and credibility of data collected throughout the study. It encompasses a systematic set of procedures designed to monitor trial conduct and data integrity, thus safeguarding the rights, safety, and well-being of participants. This review explores the principles, implementation, and evolving practices of quality control in clinical trials, highlighting its importance across all phases …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 01–07 Read article
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Automated Crop Disease Detection Using Convolutional Neural Networks
Abstract: Crop diseases contribute to major losses in agricultural production worldwide generating enormous economic costs. This study investigates the possibility of Convolutional Neural Networks (CNN) imaging techniques to auto-detect diseases associated with plants through image processing. A model was developed and trained on a publicly available plant disease dataset containing labeled images of several diseases. The CNN could classify various plant diseases with accuracy of 95%, precision of 92%, and recall …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 7–15 Read article
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Assessment of Water Quality and Quantity Trends at Reuse Locations within the Bahr El- Baqar Drainage Catchment under Water Stress Reduction Scenarios
Abstract: Many countries face the pressing challenge of water scarcity, affecting around 20% of the global population in areas with water shortages. Egypt, one of the most populous countries in Africa and the Middle East, is severely impacted by this issue. To address this, Egypt is focusing on developing alternative water resources, including the reuse of agricultural drainage water for irrigation. In this study, the SIWARE model was employed to evaluate …
Published in Journal of Water Resource Engineering and Management · Vol. 12, Issue 3, 2025 · pp. 1–11 Read article
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Drug Utilisation and Cost Analysis in End-Stage Renal Disease Patients: A Prospective Observational Study
Abstract: Chronic Kidney Disease (CKD) is a condition in which the kidneys are damaged and unable to efficiently remove waste and excess fluid from the blood. Dialysis serves as a treatment for CKD by artificially carrying out the kidney’s filtering functions. This prospective observational cross-sectional study was conducted to evaluate drug utilization patterns, economic burden, and health-related quality of life (HRQoL) among patients with end-stage renal disease (ESRD) undergoing dialysis. Over …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 2, 2025 · pp. 1–12 Read article
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An Expected Cardiovascular Disease Detection Using Deep Learning Techniques
Abstract: Many avoidable deaths globally are caused by CVD, often due to individuals remaining unaware of their risk factors until severe symptoms, such as heart attacks or strokes, appear. This study utilizes retinal images as the dataset to explore the potential of retinal imaging as a non-invasive diagnostic tool for early detection of cardiovascular diseases (CVD). The delay in diagnosis and treatment highlights the need for sophisticated diagnostic instruments that can …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 Read article
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Next-Generation Conductive Polymer Composites for Flexible and Wearable Electronics
Abstract: The rising demand for flexible and wearable electronics has accelerated research into conductive polymer composites (CPCs) due to their lightweight nature, electrical conductivity, and mechanical flexibility. Despite significant advancements, challenges such as reduced conductivity under mechanical deformation and limited durability persist. This study aims to develop next-generation CPCs with enhanced conductivity, flexibility, and self-healing capabilities. Hybrid nanofillers—graphene, carbon nanotubes (CNTs), and silver nanowires (AgNWs)—were incorporated into bio-based conductive polymers through …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 550–566 Read article
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Investigation of Sulphate, Alkali and Carbonation Chemical attack in GGBS-Based Geopolymer Concrete and OPC Concrete
Abstract: This study presents a comparative evaluation of the durability of GGBFS-based Geopolymer Concrete (GPC) and OPC concrete in rapid carbonation, sulphate, and alkali environments. All samples were subjected to three severe conditions are carbonation at 4% CO₂, 25°C and 60% relative humidity, exposure to a 10% sodium sulphate (Na₂SO₄) solution, and immersion in a 10% sodium hydroxide (NaOH) solution for alkali resistance. The durability characteristics were evaluated by the compressive …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 13–35 Read article
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Pharmacogenomics: Unlocking the Genetic Basis of Drug Response for Precision Medicine
Abstract: Pharmacogenomics, a fusion of pharmacology and genomics, explores how genetic variations influence individual responses to medications. This field is revolutionizing modern medicine by moving away from a one-size-fits-all approach toward personalized treatment strategies. By identifying specific genetic markers, pharmacogenomics aims to enhance drug efficacy, minimize adverse drug reactions, and improve overall patient outcomes. Key methodologies in this discipline include candidate gene analysis, genome-wide association studies, and haplotype analysis, all of …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 52–59 Read article
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Role of Beowulf Clusters in Next-Generation Military Applications: A Comprehensive Study
Abstract: Beowulf clusters, which utilize cost-effective commodity hardware combined with open-source software for parallel computing, have emerged as a viable and efficient solution for high-performance computing needs. This paper explores their growing relevance and practical applications in modern and future military technologies. Contemporary military operations increasingly rely on rapid data processing, real-time intelligence, high-fidelity simulations, and autonomous decision-making systems. Beowulf clusters offer scalable and adaptable computational power that supports these demands …
Published in Journal of Advances in Shell Programming · Vol. 12, Issue 2, 2025 · pp. 01–07 Read article
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Retrieval Augmented Generation for Question Answering in Financial Documents
Abstract: In recent years, the integration of Question Answering (QA) with the Retrieval Augmented Generation (RAG) system has transformed to interact with numerous documents. It uses Natural Language Processing (NLP) techniques to improve accuracy and relevant responses derived from huge documents. RAG integrates the advantages of the retrieval and generation process, which allows systems to generate natural responses and extract context from multiple sources. The main reason to use RAG is …
Published in Journal of Advanced Database Management & Systems · Vol. 12, Issue 2, 2025 · pp. 62–68 Read article