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1920 articles for “investments”
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In Silico Assessment of Demethoxycurcumin: Molecular Docking and Computational Insights into its various therapeutic Potential
Abstract: Natural compounds are increasingly explored for their therapeutic potential in medical research. Here, we focused on demethoxycurcumin (DMC), a polyphenolic bioactive compound extracted from Curcuma longa, commonly found in turmeric. DMC, with a chemical formula of C20H18O5 and a molecular weight of 340 g/mol, possesses two aromatic ring systems, each featuring a β-diketone moiety connected by a seven-carbon chain. This unique structure allows DMC to engage in tautomerism, which is …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 9–15 Read article
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Green Synthesis of Copper Nanoparticle for the Treatment of Neurodegenerative Disease
Abstract: The study of ecologically friendly CuNP synthesis is a growing area with potential applications in biomedical research and environmental remediation, as well as sustainable nanotechnology. Generally, reducing, and stabilizing agents such as microbes, plant extracts, or other natural sources are used. The green synthesis methodology guarantees the production of nanoparticles with desired characteristics for biomedical applications while simultaneously mitigating the environmental effect that comes with conventional chemical processes. CuNPs possess …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 13–24 Read article
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Structural Analysis of Heavy Vehicle Chassis Using Various Geometries and Materials
Abstract: The present research investigates the significance of the automobile chassis as a crucial section of a vehicle that provides a framework for the body and other parts to rest on. It highlights the need for the chassis to have sufficient bending stiffness for the best handling qualities, as well as enough rigidity to withstand shocks, twists, vibrations, and other loads. The draft and designing model for all the sections (I, …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 9–33 Read article
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Mechanical Characteristics of Naturally Woven Coconut Sheath/Short Sisal Fiber Reinforced Polymer Hybrid Composites
Abstract: This study presents the outcomes of an experimental investigation focusing on the tensile, flexural, impact and water absorption properties of unsaturated polyester resin reinforced with naturally woven coconut sheath and short sisal fibers. Sisal fiber, characterized by its abundance, affordability, degradability, and robust strength, serves as a compelling reinforcement. The naturally woven coconut sheath fibers, discreetly found in the hidden sections of coconut branches, offer an inexpensive, biodegradable option with …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 34–44 Read article
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Analysis of Thermo-Mechanical Properties in Cement Mortar Using Synthesized Silicate Microencapsulation of Phase Change Materials by Sol-Gel Process
Abstract: This investigation delves into improving building thermal comfort using microencapsulated phase change materials (PCM@SiO2) in cement mortar. The encapsulation process, achieved via a sol-gel method, envelops PCM in a silicate shell Differential Scanning Calorimetry (DSC) and Fourier-Transform Infrared Spectroscopy (FTIR) were used to confirm the thermal properties and integrity of encapsulated PCM, which showed an encapsulation efficiency of 92.7% and a thermal storage capacity of 99.7%. The study involved the …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 152–160 Read article
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A Comprehensive Review on Red mud as Construction Material and its Utilization for Environmental Advantage
Abstract: These materials can help to further decrease pollution and disposal difficulties when utilized effectively in civil engineering applications. Red mud, a byproduct of converting bauxite into aluminum, collects and occupies an increasing amount of deforested area because of its high alkalinity. With little chance of being used, an estimated redmud of 116 tons are created year globally, posing a major risk of contamination and pollution. However, because they will be …
Published in Journal of Construction Engineering, Technology & Management · Vol. 14, Issue 1, 2024 · pp. 35–40 Read article
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Cementing Sustainability: Utilizing Waste Foundry Sand to Enhance Concrete Performance and Reduce Environmental Impact
Abstract: The incorporation of waste foundry sand into concrete production represents an environmentally conscious and cost-effective approach. This method involves substituting discarded foundry sand for a portion of traditional fine aggregates in concrete mixtures. The primary objective is to address environmental concerns associated with waste disposal while simultaneously achieving cost efficiency in construction materials. By integrating waste foundry sand into concrete, this practice promotes sustainability by reducing landfill waste and conserving …
Published in Journal of Construction Engineering, Technology & Management · Vol. 14, Issue 1, 2024 · pp. 13–21 Read article
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Protective Effects of Phellinus linteus Polysaccharides Against Radiation-Induced Hematopoietic Damage in Bone Marrow of Mice
Abstract: Chemotherapy and radiation therapy, which are standard methods of treatment for various cancers, often result in suppression of hematopoiesis accompanied by reduction in the number of hematopoietic stem cells and their progeny. We investigated a clinically potential use of Phellinus linteus polysaccharide in the treatment of various cytopenias induced by radiotherapy. Mice were administered Phellinus linteus polysaccharide orally at a dosage of 100 mg/kg once daily for + consecutive days, …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 1, 2024 · pp. 12–17 Read article
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A Machine Learning Based Artificial Intelligence Model for Detecting Heart Illness
Abstract: This study centers around the improvement of an artificial intelligence- and computerized reasoning-based heart sickness determination framework. We exhibit how AI can help with foreseeing whether an individual will get cardiovascular infection. In this review, a Python-based application for medical care research is created since it is more reliable and helps track and lay out many kinds of well-being observing applications. We show information handling, which incorporates working with all …
Published in Journal of Computer Technology & Applications · Vol. 15, Issue 1, 2024 · pp. 50–58 Read article
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A Research on the Additives and Regulatory Requirements for Pediatric Formulation
Abstract: These days, pediatric considerations are incorporated early on in the creation of new medications. The guidelines and policies of European drug regulatory bodies served as the foundation for our investigation. The review comprehensively outlines excipients commonly found in pediatric medicine formulations. It identifies potentially harmful compounds flagged by scientific literature, stressing the necessity of rigorous safety checks, often involving toxicity studies. Excipients included in pediatric databases, like the STEP database, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 1, 2024 · pp. 28–45 Read article
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Mixed use settlements in a metro city: Effects on people & context
Abstract: Mixed-use settlement is a building or a combination of buildings designed to functionally and physically integrate multiple uses such as commercial, institutional, recreational, and other uses along with residential uses. In such spaces, there are more opportunities for pedestrian activities due to the presence of a majority of the daily necessities at near distances. How public spaces are designed plays a significant role in affecting one’s mental state and sense …
Published in International Journal of Urban Design and Development · Vol. 2, Issue 1, 2024 · pp. 22–35 Read article
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Social Capital as a Predicting Indicator to Measure the Psychological Health Impacts of COVID-19 Pandemic on Urban Societies in Pakistan.
Abstract: The COVID-19 pandemic has forced people to adapt to massive changes in their lifestyles; from health to work and how they interact with everyone nearby they know. This study aims to investigate the psychological wellbeing-impacts of COVID-19 on social capital in Pakistan. Social capital means the social and cultural coherence (as a predicting indicator) in the society. This was a survey based study conducted in 5 major cities (Islamabad, Rawalpindi, …
Published in International Journal of Urban Design and Development · Vol. 2, Issue 1, 2024 · pp. 12–21 Read article
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Late Onset Ataxia: A Case Report
Abstract: 57-year-old man with no prior history of any illness presented with subacute onset of gradually progressive gait ataxia, upper limb incoordination and speech issues. There was history suggestive of orthostatic hypotension and erectile dysfunction. On examination, there was normal cognition with gaze evoked nystagmus, scanning speech and limb incoordination in the form of past pointing, dysdiadochokinesia, and tandem walking abnormality suggestive of pan cerebellar involvement. The patient was evaluated with …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 1, 2024 · pp. 16–20 Read article
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Experimental Study on Waste Fibers in Concrete
Abstract: The rising expense of building, along with the progressive impact on the environment, has driven experts to adopt natural fibers such as coir and bamboo fibers and synthetic fibers such as plastic fibers for boosting concrete strength. Fibers are readily available at the test location, making them comparatively suitable as a reinforcing material in concrete. Concrete with fibers was compared to conventional concrete, and different strength parameters such as bending, …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 190–201 Read article
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Significance of Lighthing Design
Abstract: Lightning design plays a pivotal role in both architectural and interior design, impacting aesthetics, functionality, and psychological well-being. This research investigates the multifaceted influence of lighting on human emotions, cognitive functions, and overall mental well-being within built environments. Moreover, it explores the visual comfort aspects of lighting design, emphasizing its significance in minimizing glare, shadows, and eye strain to optimize occupant satisfaction. Through a series of case studies, this study …
Published in International Journal of Rural and Regional Development · Vol. 2, Issue 1, 2024 · pp. 37–46 Read article
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Efficacy of Combination Therapy with Osimertinib and Afatinib in epidermal growth factor receptor-mutant non-small-cell lung cancer Patients
Abstract: Treatment options for patients with non-small-cell lung cancer who have epidermal growth factor receptor mutations are constrained by the emergence of resistance to epidermal growth factor receptor tyrosine kinase inhibitors. Osimertinib or afatinib alone, when tested in a laboratory model, led to the formation of drug-resistant clones harboring epidermal growth factor receptor secondary mutations. However, combining these drugs prevented the emergence of such mutations. In a Phase II clinical trial, …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 1, 2024 · pp. 13–24 Read article
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Analyzing Failures and Challenges in Oncology: Integration of Artificial Intelligence in Healthcare
Abstract: The present study focused on investigating the challenges and failures that had been embarked during the deployment of artificial intelligence technologies within the field of oncology in healthcare. Through precise research and statistical analysis, we aimed to elucidate the specific circumstances surrounding each failure, providing insights into the root causes, consequences, and subsequent developments. The present study was aimed to offer a detailed understanding of the challenges faced through artificial …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 1, 2024 · pp. 42–50 Read article
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Assessing the Permeability of Bentonite with Sand, Marble Dust, and Fly Ash mixture with and without Effect of Permeate Solution for the Development of Efficient and Cost-Effective Landfill Liner for Sustainable Waste Management and Environmental Preservation
Abstract: This exploration paper researches the capability of further developing landfill liner materials by integrating varying percentages of bentonite into sand, marble dust, and fly ash mixtures. The study focuses on determining whether these mixtures are suitable for development of landfill liner by examining their permeability properties. Bentonite, a clay known for its high swelling and sealing properties, is added to sand, marble dust, and fly ash at different range from …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 1–11 Read article
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Reinforcement Learning in Real World Application: A Study on Robotics; Autonomous Vehicles and Industrial Automation
Abstract: This research paper investigates the practical application of reinforcement learning (RL) in three critical domains: robotics, autonomous vehicles, and industrial automation. The study delves into the implementation of RL algorithms to enhance decision-making, adaptability, and autonomy in these real-world scenarios. Through a comprehensive review of existing literature, methodologies, and case studies, the paper addresses the challenges faced and the successes achieved in deploying RL in each domain. The findings offer …
Published in International Journal of Advanced Robotics and Automation Technology · Vol. 1, Issue 3, 2023 · pp. 1–15 Read article
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Service Life Prediction of Concretes Incorporated with Fly Ash and Alccofine with respect to Chloride Ion Penetration
Abstract: Chloride-induced corrosion poses a significant threat to the degradation of reinforced concrete structures, especially in extreme environments such as marine and industrial exposure conditions, where the damage can be particularly severe. This study provides an experimental investigation utilizing three distinct water-binder ratios (0.3, 0.4, and 0.5) applied to three types of concrete mixtures: conventional concrete, concrete blended with 40% fly ash, and concrete blended with 40% fly ash and 2% …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 202–213 Read article