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1402 articles for “safe”
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Risk & Opportunities in Development of new Drugs: A New Perspective
Abstract: The procedures of drug discovery and development are briefly described in this article. Our goal is to assist researchers whose work may be pertinent to the discovery and/or development of new drugs in framing their research reports in a way that appropriately situates their findings within the drug discovery and development process and supports the efficient translation of preclinical research to humans. One overarching theme of our article is the …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 2, 2024 · pp. 19–28 Read article
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Unveiling Fairness: A Quest for Ethical Artificial Intelligence and Bias Mitigation
Abstract: Artificial intelligence (AI) systems have become ubiquitous across areas like finance, healthcare, employment, and criminal justice. However, they suffer from issues of unfair bias, lack of transparency, and broad ethical implications impacting vulnerable societal groups disproportionately. This paper reviews key challenges around AI ethics and bias while proposing data-driven guidelines mitigating such algorithmic harms through rigorous statistical testing, predictive modeling ensembles adjusting distortion vectors and AI audits by domain experts …
Published in International Journal of Information Security Engineering · Vol. 1, Issue 2, 2023 · pp. 28–31 Read article
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Effect of Nebulization With 3% Hypertonic Saline for Airway Clearance on Mechanically Ventilated Patients Admitted in ICUs of Pt. B.D. Sharma, PGIMS, Rohtak
Abstract: Background of the Study: The ability to breathe artificially prolongs life in many situations. Patients requiring mechanical breathing in the intensive care unit are more likely to have complications and even death due to a variety of interconnected causes. As a result, it became critical to rapidly ventilate in the safest and most efficient manner available. Intubated patients have benefited from nebulized suctioning, as it improves lung clearance and decreases …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 20–27 Read article
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IoT-based Smart EV Level 1 Charger: A Review
Abstract: This study presents the design and development of an IoT-based smart Level 1 charger for electric vehicles. The proposed system provides an intelligent and automated charging solution that optimizes the charging process, monitors the electricity consumption, and ensures the safety of the environment and the users. The system consists of a charging station equipped with a Wi-Fi module, a microcontroller, an LCD display, and an Android mobile application for remote …
Published in International Journal of Electrical and Communication Engineering Technology · Vol. 1, Issue 1, 2023 · pp. 14–20 Read article
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Mitigation of Location-based Attacks for Increased User Privacy
Abstract: Designing an effective method to mitigate location-based attacks is a pressing imperative in the realm of cybersecurity. As our world becomes increasingly interconnected through the Internet of Things and location-aware services, the risks associated with the misuse of location data continue to escalate. Location-based attacks encompass a spectrum of threats, from geolocation spoofing and eavesdropping to geo-tagging abuse, potentially leading to severe privacy invasions and security breaches. This abstract provides …
Published in International Journal of Mobile Computing Technology · Vol. 1, Issue 2, 2023 · pp. 1–5 Read article
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AI-driven Flood Surveillance and Dam Control: Advancing Resilience Through Data Science
Abstract: This study presents the development and real-world deployment of an intelligent system for flood monitoring and automated dam gate control using artificial intelligence (AI) and internet of things (IoT) sensors. Supervised machine learning models are developed to predict floods up to 48 h in advance. An automated dam gate operation system is designed to leverage the flood forecasts and real-time stream water levels for emergency control. The complete end-to-end infrastructure …
Published in International Journal of Data Structure Studies · Vol. 1, Issue 2, 2023 · pp. 9–17 Read article
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Comparative Study Between Dashavatara (Incarnation) and Darwinian Theory of Evolution
Abstract: The word Dashavatara derives from Dasha, meaning “Ten”, and Avatara, roughly equivalent to “Incarnation”. Lord Vishnu manifested in various avatars to safeguard the universe and reinstate “peace and dharma” during the four distinct yugas, or cosmic cycles. The Hindu text Dashavatara, which describes ten forms of Lord Vishnu, has a better developed theory of evolution than the hypothesis put out by English scientist Charles Darwin in the 17th century. Objective …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 14, Issue 1, 2024 · pp. 50–58 Read article
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An Adaptive Approach for Real-Time Embedded System Design, Analysis and Optimization
Abstract: Real-time embedded systems are critical components in various domains, such as automotive, aerospace, healthcare, and industrial automation. The design, analysis, and optimization of these systems are vital to ensure their reliable and efficient operation. In this paper, we propose an adaptive approach for real-time embedded systems that aims to address the challenges faced during the development process while maintaining high-quality results. Our approach leverages adaptive techniques to dynamically adjust the …
Published in International Journal of Solid State Innovations & Research · Vol. 1, Issue 1, 2023 · pp. 8–14 Read article
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Searchable Encryption Based on Key Aggregation
Abstract: The ability to selectively distribute data with individuals in public cloud services may alleviate safety concerns about inadvertent privacy violations in cloud storage. The need for flexibility in sharing specific sets of documents with various user groups requires the use of distinct encryption keys for each document. This undertaking tackles practical difficulties by presenting the notion of Key-Aggregate Searchable Encryption (KASE). Natural language processing was used to extract essential phrases …
Published in International Journal of Data Structure Studies · Vol. 2, Issue 1, 2024 · pp. 21–25 Read article
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Retrofitting of RC Beams Using FRP and FRCM
Abstract: The deterioration of reinforced concrete (RC) structures due to various factors such as aging, aggressive environments, or increased loads poses significant challenges to structural integrity and safety. Retrofitting techniques have emerged as effective solutions to enhance the structural performance of existing RC members. Among the retrofitting options, the use of Fibre Reinforced Polymer (FRP) and Fibre Reinforced Cementitious Matrix (FRCM) systems have gained considerable attention in recent years. The study …
Published in Journal of Polymer & Composites · Vol. 11, Issue 13, 2023 · pp. 31–40 Read article
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Sugar Substitutes: Benefit or Burden
Abstract: The ubiquitous presence of sugar in our daily diet poses a considerable impact on both dental and overall health. The consensus is clear: an excess of sugar is far from ideal. Moreover, controversial conjectures have emerged, suggesting a pivotal role of excessive sugar intake in certain degenerative diseases. In response to these concerns, artificial sweeteners, also known as sugar substitutes or low-calorie sweeteners, have become increasingly appealing to consumers.Artificial sweeteners, …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 1, 2024 · pp. 7–11 Read article
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Embryonic Advancement: An Overview from a Surgical Perspective
Abstract: The fertile ground of a mother& body serves as the nurturing environment where the seed of life can thrive, ensuring that it receives the necessary nutrients to burgeon into a robust and resilient offspring. A well-nourished mother possesses the capacity to furnish her developing fetus with all essential requirements, simultaneously building up reserves to support ample breastfeeding postpartum. This dual focus on maternal nutrition not only aims for optimal fetal …
Published in Research and Reviews : Journal of Surgery · Vol. 13, Issue 1, 2024 · pp. 19–24 Read article
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Evaluation of the anti diabetic effects of ethanolic root extract from polyalthania longifora in diabetic rats induced by streptozotin and nicotinamide with considaertion of toxocological aspects
Abstract: The root of Polialthia Longifolia was selected for the evaluation of antidiabetic potential in STZ-nicotinamide induced diabetic rat model.The root extract was extracted by hot percolation using ethanol as a solvent in soxhlet apparatus and the preliminary phytochemical screening was performed and it shows that the ethanolic root extract of Polialthia Longifolia contains alkaloids, glycosides, flavonoids and tannins. Safety profile is essential for the drugs obtained from the plant origin. …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 37–50 Read article
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Microneedles and the paradigm shift in the field of dentistry: A Review Article
Abstract: Needle-based instruments are advancing as a promising tool for both diagnosis and treatment within the medical realm. They possess versatility, being capable of drug delivery and fluid extraction, catering to both systemic and local requirements. Unlike traditional drug delivery methods, which necessitate repeated dosing in the oral cavity due to saliva presence, there's a growing demand for delivery systems like needle-based devices that can offer sustained drug release orally. These …
Published in Research and Reviews: A Journal of Dentistry Read article
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The Utilization of Oil Entrapped Floating Alginate Beads in a Gastroretentive Delivery System is Intended to Improve the Bioavailbility of Telmisartan Incorporating Principles of Bioinformatics
Abstract: Oil entrapped floating calcium alginate beads of Telmisartan were successfully prepared using sodium alginate as polymer and two different oil phases of mineral oil and olive oil by emulsion gelation method. The FT-IR spectra of final optimized formulation confirms no drug- polymer incompatibility. The floating time of beads was found to be more than 12 hrs suggesting that the method used for prepration was effective. The floating time of optimized …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 1, 2024 · pp. 21–38 Read article
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Incorporating Sensors and Algorithms for Enhanced Go-Kart Driver Awareness and Navigation
Abstract: This study is motivated by the Go Kart Design Challenge (GKDC), wherein dedicated teams from the University collaboratively endeavored to bring to life a competitive go-kart. Serving as an invaluable learning platform for mechanical engineers, the project involved comprehensive engagement in go-kart design calculations, budget estimations, fabrication, qualification testing, and dynamic participation in competitions. This paper succinctly outlines the key phases of the project, encompassing the design process, fabrication intricacies, …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 362–373 Read article
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Harmonization For Medical Device Regulation In Asia: A Vital Need
Abstract: The Medical Device area is one of the most perplexing and testing business portions of the medical services industry with a close joint effort between science and design. Notwithstanding the way that Asia has 60% of the world populace giving enormous market potential, Asian medical care consumption comprises just 15% of the worldwide medical services consumption. The sped-up maturing populace and expanding pervasiveness of ongoing infection are the key drivers …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 1, 2024 · pp. 31–37 Read article
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Role of W.A.R. Score in Predicting Wound Infection
Abstract: In clinical practice, chronic wounds are a major difficulty that are frequently made worse by the infection risk. However, the lack of precise standards for evaluating the risk of infection and establishing the need for and length of time for systemic antibiotics leads to the overuse and abuse of these drugs, which increases the risk of side effects and the development of antibiotic resistance. To close this gap, the development …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 33–38 Read article
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Molecular Docking and Interaction of Anthocyanin Derivatives in Regulating Hippo-taz Pathway for Renal Injuries
Abstract: Introduction: The Hippo pathway plays a pivotal role in renal disease, with Yes-associated protein (YAP) exhibiting promise for combined treatments. The crucial evaluation of YAP-targeted drug safety and efficacy through preclinical studies is imperative. Additionally, α-SMA and SMAD3 emerge as potential therapeutic targets in renal fibrosis, driving ongoing research toward innovative interventions. Materials and Methods: In the systematic identification of therapeutic secondary metabolites, Anthocyanin derivatives were methodically retrieved from the …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 23–38 Read article
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Recombinant Insulin
Abstract: Recombinant insulin, a revolutionary product of biotechnology, has transformed the landscape of diabetes treatment. Developed through genetic engineering techniques, recombinant insulin offers a safer, more consistent alternative to traditional animal-derived insulin. Its production involves the insertion of the human insulin gene into host organisms such as Escherichia coli or Saccharomyces cerevisiae, which serve as efficient factories for insulin synthesis. Recombinant insulin is used to treat diabetic patients who are allergic …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 39–43 Read article