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829 articles for “guide”
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Prime Editing and Base Editing in Human Hematopoietic Stem Cells Toward Scarless Correction of Monogenic Blood Disorders
Abstract: Monogenic hematological disorders – such as sickle cell disease (SCD), β-thalassemia, and X-linked chronic granulomatous disease (X-CGD) – affect >400, 000 newborns worldwide each year, with a considerable burden in low-resource settings . Although donor-derived allogeneic hematopoietic stem-cell transplantation (HSCT) is widely regarded as curative, its application is limited due to issues of donor availability and graft-versus-host disease (GVHD) and conditioning-related toxicity. DSB-based conventional CRISPR-Cas9 strategies are limited by inefficient …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 1, 2026 Read article
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PERFORMANCE-BASED WIND RESPONSE ANALYSIS OF TALL RCC IREGULAR STRUCTURES USING AUTODESK REVIT AND ROBOT STRUCTURAL ANALYSIS
Abstract: The increasing trend of vertical construction has made wind effects a critical consideration in the design of tall reinforced concrete (RCC) buildings. The response of such structures is largely governed by their geometric configuration, stiffness characteristics, and modelling accuracy under wind loading conditions Wind loads are evaluated based on standard provisions such as IS 875 (Part 3): 2015, which provide essential guidelines for structural safety This study focuses on evaluating …
Published in Journal of Structural Engineering and Management · Vol. 13, Issue 3, 2026 Read article
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An in-Depth Analysis of Cyber Security: Vulnerabilities, Threat Landscapes, Attack Mechanisms, and Defense Solutions
Abstract: In a highly digitalized world today, cyber security has taken over as a necessary component to safeguarding the modern world technology. With the increase in the dependency on the digital platform and online services, the threat of cyber threats has also risen. Such threats are not confined to mere attacks anymore, as they have taken a new form of complexity and magnitude to impact individuals, businesses, government institutions among others. …
Published in Journal Of Network security · Vol. 14, Issue 2, 2026 Read article
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A Constraint-Driven Generative Design Methodology for Modular Actuated Robotic Components in Decentralized Manufacturing
Abstract: This work formalizes a constraint-driven generative design framework for actuator-integrated robotic components intended for decentralized additive manufacturing. Conventional topology optimization typically prioritizes structural efficiency while treating actuator integration, modular interfaces, and fabrication constraints as secondary considerations. In contrast, the proposed methodology encodes these requirements as first-order geometric and mechanical constraints prior to automated material redistribution. The framework defines preserved actuator geometry, bounded design envelopes, representative loading abstractions, and manufacturability-aware domains …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 4, Issue 1, 2026 · pp. 1–12 Read article
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Design Strategies of Polymer Composite Components for Sustainable Renewable Energy Microgrids
Abstract: Increasing power demand and variable performance requirements in renewable-energy systems motivate integrating advanced polymeric and composite materials into microgrid components to improve reliability and performance. This paper presents a design and control framework for a standalone microgrid that couples power-electronic and energy-conversion subsystems with polymer-composite–based components to enhance durability, thermal management, and electromagnetic shielding. The microgrid uses a doubly fed induction generator (DFIG) for wind generation to enable independent active …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 63–71 Read article
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Deep Learning models for real time detection of crop diseases in the Maharashtra/Mumbai district
Abstract: This research project addresses the critical agricultural challenge of crop disease management in the Maharashtra region of India by leveraging modern deep learning techniques. The primary objective is to identify, implement, and compare the efficacy of various deep learning architectures—including Convolutional Neural Networks (CNNs), MobileNet, and EfficientNet—for the real-time classification of diseases in key crops such as cotton, soybean, and sugarcane. A custom dataset of agricultural images specific to Maharashtra's …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 15, Issue 2, 2026 · pp. 36–48 Read article
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Sanskruti AI : Rediscovering Indian Culture Using Artificial Intelligence
Abstract: Away from old ways, many young people in India now find customs hard to reach, losing touch with sacred texts, local traditions, and deeper beliefs. Into this space steps Sanskruti AI - an intelligent tool using sound, text, and vision to bring culture closer, tailored to how today & users think and feel. Instead of flat translations, it unpacks verses from Sanskrit with layers: word-for-word sense, background context, inner meaning. …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 16, Issue 2, 2026 · pp. 30–36 Read article
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Viscoelastic Behavior, Interfacial Mechanics, and Reliability of Polymer Interlayers in Laminated Glass Composites: A Comprehensive Review
Abstract: The laminated glass systems are regarded as hybrid polymer–glass composites where the viscoelastic behavior of polymer interlayers mostly controls mechanical response. These interlayers (polyvinyl butyral (PVB), ionoplast, ethylene-vinyl acetate (EVA), etc.) have time-, temperature- and rate-dependent properties which significantly affect shear transfer, energy dissipation, and fracture resistance. But the baseline polymer-relevant processes at the molecular and interfacial level are to a large extent unknown [1]. This review provides a materials-focused …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 258–268 Read article
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Machine Learning Based Optimization of Polymer Structure Property Relationships in Composite Material Systems
Abstract: In modern engineering applications, polymer-based composite materials have garnered a lot of attention because of their lightweight nature, high strength-to-weight ratio, and changing physical features. In order to maximize the relationships between polymer structure and properties in composite materials, this study suggests a strategy based on reinforcement learning (RL). The research utilized the Polymer Composite Properties Dataset, which contains 12,700 records associated with polymer matrices, reinforcement fillers, interfacial bonding characteristics, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 242–255 Read article
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Impact of Clinical Simulation-Based Learning on Nursing Students’ Competency and Confidence: A Cross-Sectional Study
Abstract: Simulation-based learning (SBL) has emerged as a vital component in nursing education, offering students a safe, structured, and controlled environment to practice clinical skills. This study aimed to assess the impact of SBL on clinical competency and confidence among B.Sc. Nursing students. A cross-sectional study design was adopted, involving 120 B.Sc. Nursing students from Stephens College of Nursing, Stephens Group of Institutions, Jammu. Data were collected using a structured questionnaire …
Published in Journal of Nursing Science & Practice · Vol. 16, Issue 1, 2026 · pp. 11–16 Read article
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Group-Theoretic Symmetry Indices for Modular Building Layouts under Seismic Load Redistribution
Abstract: Symmetry in modular buildings operates simultaneously as an architectural language, a structural regularizer, and a computational design variable. This paper develops a group-theoretic framework for evaluating and optimizing plan symmetry in modular buildings subjected to seismic load redistribution. The building layout is modeled as a finite occupancy–stiffness field defined on a rectangular lattice, where each module encodes both mass and stiffness contributions. Planar reflections and quarter-turn rotations are represented as …
Published in Emerging Trends in Symmetry · Vol. 2, Issue 1, 2026 · pp. 01–07 Read article
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A Study to Assess the Knowledge and Practice Regarding Prevention of TB Among Staff Nurses Working in a Selected TB Hospital at Jodhpur
Abstract: Tuberculosis (TB) remains a major global public health concern, causing significant morbidity and mortality, particularly among healthcare workers. Staff nurses are at heightened risk due to repeated exposure to patients with active TB, making knowledge and adherence to preventive practices critical. The present study was conducted to evaluate the knowledge and practices of staff nurses concerning tuberculosis (TB) prevention at Kamla Nehru TB and Chest Hospital, Jodhpur. A descriptive and …
Published in International Journal of Community Health Nursing And Practices · Vol. 4, Issue 1, 2026 · pp. 7–33 Read article
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Dissipative Particle Dynamics Simulation Study on the Evolution of Photoinitiated Free Radical Polymerization Crosslinked Networks
Abstract: Gradient polymer materials overcome the limitations of conventional homogeneous polymers by integrating multiple distinct functionalities within a single continuous structure. Although photoinitiated free-radical polymerization offers excellent spatial and temporal control, the underlying microscopic mechanisms governing network evolution under non-uniform light fields remain poorly understood. In this study, a mesoscale dissipative particle dynamics (DPD) model was successfully developed to couple free-radical polymerization kinetics—including initiation, propagation, crosslinking, and termination—with exponential light attenuation …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 142–158 Read article
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A Review on Integrated Acoustic Emission and Piezoelectric Sensing for Real-Time Damage Characterization of Polymer Composite-Enhanced Concrete: Advances, Challenges, and Future Perspective
Abstract: Polymer composite reinforced concrete has been identified as an efficient material system that can enhance the mechanical properties, durability, and service life of modern structures. The combination of fiber reinforced polymers (FRPs), polymer modifiers, and hybrid composite reinforcements increases structural effectiveness. However, these systems are still vulnerable to damage processes, including matrix cracking, fiber breaking, interfacial debonding, and delamination. Thus, there is a need for structural health monitoring (SHM) strategies …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 930–939 Read article
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Diffusion-Based Enhancement of Low-SNR Time- Frequency Signals
Abstract: Traditional enhancing techniques are useless in low signal-to-noise ratio (LSNR) situations because noise drastically interferes with communication signals. Based on an enhanced DiffBIR model, this paper suggests a dual-stage signal improvement approach that combines diffusion with deep learning. By combining the Inception module for multi-scale feature extraction with the Pixel Fusion Attention (PFA) module for significant region highlighting, the model improves signal recovery in the time- frequency domain. Experiments show …
Published in Current Trends in Signal Processing · Vol. 16, Issue 2, 2026 · pp. 15–27 Read article
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Prospects and Growth Opportunities of Female-Owned Rural Farm Businesses in Plateau State, Nigeria
Abstract: The potential and growth chances of female-owned rural agricultural companies in Nigeria's Plateau State were investigated in this study. The objectives were to assess the prospects and opportunities available to female-owned rural farm businesses and to determine their effect on business growth and development across the state. The study covered female farm business owners engaged in crop production, livestock farming, mixed farming, and agro- processing across all 17 Local Government …
Published in Journal of Energy, Environment & Carbon Credits · Vol. 16, Issue 2, 2026 Read article
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Attitude of Undergraduate Agriculture Students Towards Farming: Empirical Evidence From a Premier State Agricultural University in India
Abstract: Agricultural education plays a critical role in developing skilled human resources for sustaining and revitalizing the farming sector in India. Despite agriculture being the backbone of the national economy, there is increasing concern about the declining inclination of educated youth towards farming as a profession. The present study was undertaken to assess the attitude of undergraduate agriculture students towards farming and to examine selected socio-demographic, educational, economic, and psychological factors …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 15, Issue 2, 2026 · pp. 41–56 Read article
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Investigation on mechanical performance of 3D printed PLA-Kraft Lignin composites
Abstract: Bio-based polymer composites are becoming more popular due to the growing need for sustainable and biodegradable materials in additive manufacturing. PLA-kraft lignin composites were created and their mechanical performance in fused deposition modeling (FDM) applications was assessed in this work. Polylactic acid (PLA) was mixed with Kraft lignin, a sustainable by-product of the paper industry, at weight percentages of 0%, 1%, 3%, 5%, and 7%. Melt blending was utilized to …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 1002–1015 Read article
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Systematic Analysis of the Therapeutic Potential of Bacopa monnieri: A Wonder Therapeutic Plant
Abstract: Bacopa monnieri (L.) Wettst., a well-known perennial creeping herb, native to parts of America, the African subcontinent, and South Asia, had been a well-known nootropic plant, documented in ancient Indian systems of medicine, Ayurveda. The dynamic variations in the phytocompounds consortia, regulated by abiotic cultivation conditions and germplasm, provided a paradigm shift towards the exploring profound therapeutic effect of the plant along with advancements in scalable cultivation strategies. Tailoring the …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 2, 2026 · pp. 39–46 Read article
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Bridging Traditional Ayurvedic Pedagogy and Competency-Based Education: A Contemporary Perspective
Abstract: Mentoring plays a pivotal part in education. It has deep roots in both the traditional practitioner- Shishya Parampara of Ayurveda and ultramodern faculty- grounded medical education. The National Medical Commission and the National Commission for Indian System of Medicine have stated that structured mentorship programs are essential to guide scholars from newcomers to interpreters. This composition looks at how these traditions connect. It explains the purpose and limits of mentoring. …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 15, Issue 2, 2026 Read article