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918 articles for “Bars”
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Emerging Therapies in Respiratory Tract Infections: Current Advances and Future Perspectives
Abstract: The impact of respiratory tract infections (RTI) as a global public health problem continues to be high morbidity and mortality rates. The development of novel therapeutic approaches stemmed from the fact that conventional treatment strategies, antibiotics, antivirals, antifungals etc. have become increasingly ineffective because of rise of antimicrobial resistance (AMR). Next generation therapies, such as novel antimicrobial agents, host directed therapies and novel drug delivery systems have come on the …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 17–25 Read article
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Nitro IDE: Exploring Integrated Development Environments: Current Trends and Innovations
Abstract: Integrated Development Environments (IDEs) have become essential in modern software development, offering a centralized platform that brings together source code management, debugging tools, version control, and compilation features. This study offers an in-depth analysis of various IDE platforms, with a particular focus on Eclipse as a widely used open-source integration environment. It also explores specialized IDEs tailored for embedded systems and enterprise-level Java (J2EE) application development. Additionally, the study examines …
Published in Journal of Open Source Developments · Vol. 12, Issue 2, 2025 · pp. 35–40 Read article
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Environmental and Sanitation Challenges and Their Role in Malaria Transmission: A Case Study of Duport Road Community, Paynesville City, Liberia
Abstract: Introduction: Environmental sanitation plays a crucial role in controlling malaria transmission, yet several factors continue to impede its effectiveness, particularly in communities with poor waste management and drainage systems. This study explores the factors that hinder proper environmental sanitation and their association with the spread of malaria among residents of Duport Road Community, Paynesville City, Liberia.Methods: A descriptive cross-sectional study was conducted, gathering data from 400 participants—both men and women—between …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 2, 2025 · pp. 24–29 Read article
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Topology and Geometry in Data Science: Persistent Homology and Beyond
Abstract: In recent years, the interplay between topology, geometry, and data science has gained substantial momentum, offering powerful frameworks to analyze and interpret complex datasets. Traditional statistical and machine learning methods often rely on linear or metric- based assumptions, which may fail to capture the intrinsic structure of high-dimensional or nonlinear data. In contrast, topological and geometric methods provide shape-oriented, scale- invariant tools that focus on the continuity, connectivity, and global …
Published in Recent Trends in Mathematics · Vol. 1, Issue 2, 2024 · pp. 21–27 Read article
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Optimizing Glass to Metal Composite Seal Performance: An integrated Approach with Artificial Neural Network, Multiple Regression, and Taguchi
Abstract: Composite materials, particularly glass to metal composites, are critical components in solar receiver tubes, where vacuum leakage can significantly compromise the efficiency of solar plants. This research addresses the technical barriers associated with the development of durable and high-quality glass to metal composite seals. We investigate the principles that can enhance the physical and chemical properties of these composite seals, focusing on the incorporation of TiO2 and MgO nanoparticles into …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 418–435 Read article
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Evolution of Lean Manufacturing in Mechanical Industries: From Traditional Tools to Digital Transformation
Abstract: Lean manufacturing has long been a foundational strategy for enhancing productivity, reducing operational waste, and improving overall efficiency in mechanical industries. Initially developed as part of the Toyota Production System, lean principles focused on eliminating non-value-adding activities and streamlining processes using a set of well-established tools such as 5S, Kaizen, Kanban, and value-stream mapping. Over the decades, these principles have been adopted and refined globally, particularly within the mechanical sector, …
Published in Journal of Production Research & Management · Vol. 15, Issue 2, 2025 · pp. 13–18 Read article
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The Impact of Geographical Indications on Sustainable Rural Development: Comprehensive Economic and Cultural Insights from Wayanad, Kerala
Abstract: Geographical Indications (GIs) play a vital role in fostering sustainable rural development by linking unique local products to their geographic origins. This study explores the impact of GIs on economic growth, cultural preservation, and environmental sustainability in Wayanad, Kerala. Drawing from extensive secondary data and detailed case studies including Wayanad Coffee, Jeerakasala Rice, and traditional handicrafts, the research highlights how GI certification enhances market value, improves income levels, and preserves …
Published in International Journal of Rural and Regional Development · Vol. 3, Issue 2, 2025 · pp. 18–29 Read article
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Advancing Cancer Vaccine Development through CRISPR/Cas9 Technologies and Future Opportunities
Abstract: The advent of CRISPR/Cas9 genome editing has revolutionized the cancer immunotherapy market, offering unprecedented precision and versatility in the development of next-generation cancer vaccines. This review examines how CRISPR technologies are being integrated into various stages of cancer vaccine development including neoantigen discovery, dendritic cell engineering, cancer cell reprogramming, and tumor microenvironment modulation. In the area of neoantigen discovery, CRISPR enables rapid identification and validation of tumor-specific mutations, thereby supporting …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 Read article
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Innovations in Targeted Drug Discovery for Personalized Medicine
Abstract: Personalized medicine is revolutionizing modern healthcare by custoizing treatment plans to match an individual’s genetic makeup, protein expression, and metabomlic characteristics. Also referred to as precision medicine, this approach seeks to improve therapeutic outcomes, reduce adverse effects, and make efficient use of healthcare resources. The incorporation of various omics technologies—including genomics, proteomics, transcriptomics, metabolomics, and epigenomics—has greatly advanced our ability to understand disease biology and molecular variations specific to each …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 19–41 Read article
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Rethinking Consumer Preferences for Broiler Meat: Addressing Public Concerns for Sustainable Development
Abstract: Broiler meat is a crucial component of global protein consumption, yet its acceptance is often hindered by concerns related to health, animal welfare, environmental sustainability, and consumer perception. This study examines the factors influencing consumer preferences for broiler meat and explores strategies to address public concerns while promoting sustainable development. Misinformation regarding antibiotic residues, growth promoters, and broiler welfare has contributed to negative consumer sentiment, leading to a preference for …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 2, 2025 Read article
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Drug Screening Using Stem Cell Technology
Abstract: Stem cell technology in drug screening has transformed the research and development sector of pharmaceuticals. Although stem cells imitate their human counterparts in terms of both safety and potential, it is a new paradigm for mimicking diseases of humans and scale measuring for toxicity. These tissues will, therefore, be more predictive of what will happen in humans during clinical situations, compared to conventional cell lines or animal models, since they …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 42–51 Read article
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Beyond Generalized Treatment: The Future is Personalized Medicine
Abstract: Personalized medicine, which is also called as precision medicine, is reestablishing the view of new healthcare by replacing the traditional "one-size-fits-all" approach with individual therapies made according to a patients unique genomic organization, environment, and lifestyle. This article talks about the scientific foundation, important applications, ethical challenges, and the significant potential of personalized medicine in enhancing the clinical outcomes. From oncogenic and genetic disorders to chronic diseases, the addition of …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 2, 2025 Read article
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Phyto-Entrapped Carbon Dots as Emerging Nanomaterials for Anti-Cancer Activity
Abstract: Phytoconstituent-loaded carbon dots (C-dots) represent an innovative approach in targeted cancer therapy, combining the therapeutic power of plant-derived compounds with the advanced capabilities of nanotechnology. These ultra-small, biocompatible nanostructures offer excellent fluorescence, tunable surface chemistry, and low toxicity, making them ideal for drug delivery, bioimaging, and theranostic applications. Traditional phytochemicals often face challenges like poor solubility, low bioavailability, and high first-pass metabolism barriers that C-dots help overcome. C-dots synthesized through …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 51–63 Read article
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Polymer-Nanowire Hybrid Composites Based on PEDOT: PSS and AgNWs for High-Performance Conductive Films in Flexible Devices
Abstract: The growing demand for flexible photovoltaic and wearable optoelectronic devices has intensified research into polymer-based conductive composites that provide transparency, flexibility, and electrical efficiency. In this work, we report the fabrication and characterization of a hybrid polymer nanocomposite electrode comprising silver nanowires (AgNWs) embedded within a PEDOT:PSS matrix, deposited on flexible polyethylene terephthalate (PET) substrates. The PEDOT:PSS polymer phase, modified with 5 vol% dimethyl sulfoxide (DMSO) and 0.1 vol% Zonyl …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 236–250 Read article
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Pharmacogenomics: Unlocking the Genetic Basis of Drug Response for Precision Medicine
Abstract: Pharmacogenomics, a fusion of pharmacology and genomics, explores how genetic variations influence individual responses to medications. This field is revolutionizing modern medicine by moving away from a one-size-fits-all approach toward personalized treatment strategies. By identifying specific genetic markers, pharmacogenomics aims to enhance drug efficacy, minimize adverse drug reactions, and improve overall patient outcomes. Key methodologies in this discipline include candidate gene analysis, genome-wide association studies, and haplotype analysis, all of …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 52–59 Read article
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Physical Activation Process and Characterization of Bioactive Carbon, with a Focus on its Applications
Abstract: Activated carbon is a form of carbon that has been processed to enhance its surface area and porosity. This processing enables it to function as an efficient adsorbent, attracting and retaining other molecules on its surface. In our environment, many types of biomass waste are inexpensive and renewable. Recently, there has been a growing interest in producing products from renewable resources. A prime example is the use of biomass to …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 507–517 Read article
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Advancing Gene Therapy: Next-Generation Viral Vector Engineering for Precision, Safety, and Scalability
Abstract: Gene therapy has emerged as a paradigm-shifting modality for the treatment of genetic disorders, malignancies, and rare diseases through the delivery of therapeutic nucleic acids aimed at correcting or modulating dysfunctional gene expression. Among the various delivery systems, viral vectors including adeno-associated viruses (AAVs), lentiviruses, adenoviruses, retroviruses, and herpes simplex viruses have proven indispensable owing to their high transduction efficiencies and adaptability. This review offers a comprehensive assessment of viral …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 37–55 Read article
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Influence of Static Sequences on the Thermal Behavior of Eco-Friendly Pineapple/Ramie Composites
Abstract: The increasing demand for sustainable and environmentally responsible materials has driven the exploration of natural fiber-reinforced polymer composites as potential alternatives to conventional synthetic materials. Among various natural fibers, pineapple leaf fiber (PALF) and ramie fiber are notable for their complementary characteristics—PALF offers excellent insulating behavior and lightweight structure, while ramie provides high thermal stability and strength. In the field of Eco-friendly composite product manufacturing, the processing temperature holds significant …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 732–742 Read article
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Performance, Emission, and Combustion Evaluation of Chlorella Vulgaris Biodiesel-Diesel Blends in a Compression Ignition Engine
Abstract: This study examines, without modifying the engine, the performance, emissions, and combustion properties of biodiesel blends made from Chlorella vulgaris microalgae in a four-stroke, single-cylinder, water-cooled CI engine. The blends of biodiesel and diesel, designated B10, B20, B30, and B40, were 10%, 20%, 30%, and 40%, respectively. Of these, B20 showed the best efficiency-to-emissions ratio. Although it recorded the lowest brake specific fuel consumption of 0.232 kg/kWh, indicating superior fuel …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 339–354 Read article
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The Evolution and Future Prospects of Solar Energy in India
Abstract: India has made great strides in incorporating solar energy into its renewable energy framework thanks to its plentiful solar resources. This case study examines the nation's advancements in solar energy development, the challenges it still faces, and its prospects for growth. India has aggressively pushed solar efforts to satisfy expanding energy demands responsibly and lessen reliance on fossil fuels, thanks to the country's high levels of sun irradiation in most …
Published in Journal of Energy, Environment & Carbon Credits · Vol. 15, Issue 3, 2025 · pp. 54–59 Read article