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284 articles for “tolerance”
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Immunological Mechanisms Underlying Autoimmune Disorders: Recent Advances and Therapeutic Implications
Abstract: A diverse range of illnesses known as autoimmune disorders are typified by dysregulated immune responses against self-antigens, which result in tissue damage and persistent inflammation. Understanding the genetic, epigenetic, and environmental variables that contribute to autoimmune pathogenesis has advanced significantly during the last ten years. Current disease models have been transformed by new understandings of immunological tolerance mechanisms such as the functions of regulatory T cells, cytokine networks, and the …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 1, 2026 · pp. 21–25 Read article
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Systemic Lupus Erythematosus Revisited: A Milestones in Classification, Mechanistic Insights on Pathogenesis, Diagnosis, and Evolving Treatment Paradigms
Abstract: Systemic lupus erythematosus (SLE) is a prototypic, multi-systemic chronic inflammatory autoimmune disorder characterized by extreme clinical heterogeneity and the potential to involve virtually any organ or tissue. The condition is driven by a fundamental breakdown in immune tolerance, resulting in the overproduction of pathogenic autoantibodies and the formation of immune complexes that precipitate widespread inflammation and organ damage. This review aims to provide an exhaustive synthesis of recent developments in …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 3, 2026 Read article
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Advancing Climate-Resilient Agriculture: Integrative Biotechnological Approaches for Sustainable Crop Production
Abstract: Climate change presents a major challenge to global agriculture by increasing the occurrence and severity of both non-living and living stress factors, such as drought, high temperatures, salt buildup, waterlogging, and new pests and diseases. These stressors interfere with the normal functioning of plants at the physical, chemical, and genetic levels, which in turn results in lower crop yields and poorer quality. While traditional methods of plant breeding played a …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 2, 2026 Read article
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A Hierarchical Orchestration Framework for Parallelized Multi-Entity Web Ingestion and NoSQL Synchronization
Abstract: In the current EdTech sector, gathering structured data from various fragmented web portals is a major challenge for building reliable, real-time data systems. Standard sequential ETL (Extract, Transform, Load) pipelines often encounter significant bottlenecks, as a single failure in one module can halt the entire ingestion process. Furthermore, linear execution is often too slow to meet the demands for large, multi-category datasets. This paper presents a Modular Hierarchical Orchestration framework …
Published in Recent Trends in Parallel Computing · Vol. 13, Issue 2, 2026 · pp. 1–6 Read article
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A Depth Look of Vehicular Technology for Sustainable Development through DTN in India
Abstract: AbstractThis paper notes that education also results in technical development serving with the purpose that overall development of technology in term of living standards to up-lift. In its current state, technical education does not appear to serve the on top objectives. The paper presents a holistic read of technical education in Bharat. To confirm multidimensional sustainable development indicators (MSDI) for Bharat within the up to date correlated main element of …
Published in Journal of Mobile Computing, Communications & Mobile Networks · Vol. 7, Issue 3, 2020 · pp. 18–24 Read article
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Evaluation of J-Integral and Fatigue Crack Growth Rate of Semi-elliptical Crack in Compressor Blade
Abstract: Gas turbine compressor blades are subjected to centrifugal, gas bending and vibratory loads. This repeated loading and unloading can reduce the life of compressor blades. This research aims at the estimation of fatigue crack growth rate of various three-dimensional cracks in a compressor blade considering the J-integral calculations for a semi-elliptical crack, subjected to centrifugal loading. Static stress analysis was carried out to ascertain the critical region or crack zone …
Published in Trends in Mechanical Engineering & Technology · Vol. 4, Issue 2, 2014 · pp. 39–46 Read article
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Protein Metabolism in Plants during Abiotic Stress (Drought, Flood, Heat and Cold): An Overview
Abstract: Plants are frequently subjected to several abiotic environmental stresses under natural conditions causing profound impacts on agricultural yield and quality. Tolerance and acclimation of plants are always related with significant changes in protein, cellular localization, post transcription and post-translational modifications. Protein response pathways as well as pathways unique to a given stress condition shared by plants under different stressed environment are discussed. In a nutshell, this paper provide an overview …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 10, Issue 3, 2020 · pp. 21–45 Read article
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The Mechanism of Soil Salinity and Plant Response: An Update Review
Abstract: AbstractSalinity, the abiotic stress of soil is one of the major concerns for agriculture and sustainable development. It affects large terrestrial areas including arable land. That’s why agricultural productivity is reducing day by day. The main remedy lies within the development of salt tolerant crops. In this respect, coordinated and tissue-specific processes like osmotic tolerance, K+ accumulation in cytoplasm, Cl− tolerance, Na+ exclusion, tissue tolerance etc. throughout the life cycle …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 2, Issue 1, 2013 · pp. 20–28 Read article
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Automatic Fire Extinguisher Sprinkler System: An Innovative Solution for Fire Safety
Abstract: The Automatic Fire Extinguisher Sprinkler System is an advanced safety feature designed to quickly respond to fires in buildings. This system automatically detects heat or smoke and releases fire-suppressing agents to put out the flames before they can spread. The persistent risk of fire hazards in various sectors, including residential and commercial environments, has led to the innovation of sophisticated fire safety systems. Among these, the automatic fire extinguisher sprinkler …
Published in Journal of Thermal Engineering and Applications · Vol. 12, Issue 1, 2025 · pp. 41–46 Read article
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Association Between Smartphone Addiction and Functional Exercise Capacity in College Students
Abstract: Smartphone addiction has become increasingly prevalent among college students and is associated with various negative physical and psychological outcomes. Functional exercise capacity, a key indicator of physical fitness and health, may be adversely affected by excessive smartphone use due to sedentary behavior and reduced physical activity. This article examines the association between smartphone addiction and functional exercise capacity in college students by analyzing behavioral, psychological, physiological, and methodological perspectives. Evidence …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 4, Issue 1, 2026 · pp. 28–51 Read article
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Resilient Shell-Based Frameworks for Edge and IoT Systems: A Comprehensive Analysis of Lightweight Automation in Distributed Environments
Abstract: Edge computing and Internet of Things (IoT) deployments require automation solutions that minimize resource use while supporting real-time processing and intermittent connectivity. This study investigates shell-based frameworks for managing distributed edge and IoT systems, with emphasis on sensor integration, live monitoring, and fault recovery. Drawing from 200 real-world deployment cases across smart city, healthcare, and industrial domains, the analysis compares shell scripting directly against containerized approaches (e.g., Docker with lightweight …
Published in Journal of Advances in Shell Programming · Vol. 13, Issue 1, 2026 · pp. 01–07 Read article
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Evaluation of J-Integral and Fatigue Crack Growth Rate of Semi-elliptical Crack in Compressor Blade
Abstract: Gas turbine compressor blades are subjected to centrifugal, gas bending and vibratory loads. This repeated loading and unloading can reduce the life of compressor blades. This research aims at the estimation of fatigue crack growth rate of various three-dimensional cracks in a compressor blade considering the J-integral calculations for a semi-elliptical crack, subjected to centrifugal loading. Static stress analysis was carried out to ascertain the critical region or crack zone …
Published in Journal of Mechatronics and Automation · Vol. 1, Issue 2, 2014 · pp. 39–46 Read article
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A Precise Clock Synchronization Algorithm in Network
Abstract: To execute a task in a synchronized manner in a distributed setting, we need the common idea of time. To accomplish this intention, clock synchronization is conceptualized. Clock drifting is an intrinsic property of a clock, which necessitates the synchronization. A network consists of nodes, which may execute appropriately or behave badly. The mischievous node may pose difficulty in clock synchronization. We require a method to ease the effect of …
Published in Journal of Communication Engineering & Systems · Vol. 10, Issue 1, 2020 · pp. 12–21 Read article
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Current Issues in Understanding of Diabetes
Abstract: Diabetes mellitus is a significant metabolic disorder that poses a major health concern, particularly in India. India harbours the world's highest number of diabetic patients, totalling around 130 million, with an additional 40 million categorised as prediabetic. In the global context, the number of adults suffering from diabetes was roughly 150 million in 2000, but this number is projected to significantly increase by 2030. The global prevalence of prediabetes is …
Published in Research and Reviews: A Journal of Medicine · Vol. 13, Issue 2, 2023 · pp. 1–12 Read article
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Opportunistic Network Environment: A Multipurpose Simulation Tool for Wireless Networks
Abstract: In this paper, ONE simulator and its working is discussed with some practical examples. How to practically use ONE simulator is described in easy and proper manner. ONE is a wireless simulator used to simulate different wireless networks. In this simulator, different routing protocols, different attacks occurred in routing protocols can be implemented. Energy analysis congestion control can also be implemented in this simulator. This simulator is open, accessible, easy-to-use …
Published in Journal of Open Source Developments · Vol. 2, Issue 2, 2015 · pp. 30–34 Read article
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Effect of Salt Stress on Plants: A Review
Abstract: AbstractSalinity may be a major abiotic stress, limiting growth and productivity of plants in many areas of the world. The ability of plants to tolerate salt is set by multiple biochemical pathways that facilitate retention and/or acquisition of water, defend plastid functions, and maintain ion homeostasis. The ability of plants to detoxify radicals underneath conditions of salt stress is perhaps the foremost essential demand. Several salt-tolerant species accumulate methylated metabolites …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 4, Issue 3, 2015 · pp. 35–51 Read article
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Elucidating the Role of Temperature in Reproductivity of Plants
Abstract: Analysis on plant counter to temperature stress accumulates interest because of the expanded mindfulness with respect to an unnatural weather change. High and low temperature stresses help in setting up the slight natural division of refined plants, the restricted geographic expansion of some other financially healthfully significant species, and furthermore produce lopsided connection for certain species. All things considered, the view of plant reprisal to temperature stress falls behind other …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 10, Issue 1, 2021 · pp. 19–27 Read article
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Water Stress: An Overview on Plant Life
Abstract: AbstractPlant water status determines the tolerance and escapability of a plant towards the drought or other stress. There are morphological, physiological and biochemical significance of the drought. Plants have the drought tolerance capability by changing its physiology and biochemical compounds. The accumulation or relocation of the bio compounds determines the stress tolarance capacity and those compounds are called stress tolerance compounds. In normal they are the middle or end product …
Published in Research & Reviews : Journal of Ecology · Vol. 3, Issue 3, 2014 · pp. 12–26 Read article
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A Unified Ultra-Low Power Architecture of Probabilistic Adder Based on GDI Technique
Abstract: In the present arena of technology scaling, the power consumption in the deep submicron technology plays a pivotal role as the transistor counts increases dramatically. Therefore, the need of the hour is to focus on power dissipation. The rate of occurrences of errors in the present VLSI scenarios has become higher and inevitable, and is increasing along with technology scaling. Eradicating all the errors is a cumbersome task; still a …
Published in Journal of VLSI Design Tools and Technology · Vol. 6, Issue 3, 2016 · pp. 45–55 Read article
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Evaluation of the Effect of Zinc Supplementation on Glycemic Control and Lipid Profile in Normoglycemic and Streptozotocin-induced Type-2 Diabetic Rats
Abstract: Diabetes mellitus is a chronic, progressive disease, which is accompanied by multiple complications. Hyperglycemia and dyslipidemia are common complications of diabetes mellitus. The current approaches for treatment of diabetes are mostly dependent on insulin and other oral standard drugs, which have their own put falls. Thus, micronutrients supplementation is gaining momentum as the quest for management of diabetes continues. Certain micronutrients increase insulin synthesis secretion and insulin sensitivity thereby improve …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 5, Issue 2, 2016 · pp. 41–51 Read article