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105 articles for “likelihood”
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The Poisson–Uma Distribution with Properties and Applications to Model Thunderstorm Events
Abstract: The discrete data available in any field of knowledge is influenced by several known and unknown factors and the factors which affect the discrete data are stochastic. The stochastic nature of discrete data is a challenge for statisticians to model and analyze with the existing discrete distributions. In the present paper, Poisson-Uma distribution, the Poisson compound of Uma distribution, has been proposed to model over-dispersed data of thunderstorm events. The …
Published in Research & Reviews : Journal of Statistics · Vol. 13, Issue 1, 2024 · pp. 20–30 Read article
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Computational Biomodeling: Transforming Drug Design with Advanced Simulations
Abstract: Computational biomodeling has emerged as a transformative approach in the field of drug discovery, significantly enhancing the efficiency and precision of identifying and optimizing potential drug candidates. This article explores the various computational techniques utilized in drug design, including molecular docking, molecular dynamics (MD) simulations, free energy calculations, and virtual screening, and examines how these methods collectively contribute to the drug development process. The integration of these advanced simulations allows …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 3, 2024 · pp. 24–29 Read article
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IoT-based Heart Attack Prediction System Using Machine Learning
Abstract: Heart disease, particularly heart attacks, is one of the leading causes of mortality worldwide. Timely detection and prompt intervention play a vital role in significantly improving the survival rates of individuals at risk of cardiac events. Unfortunately, most traditional healthcare systems are not equipped with mechanisms for continuous, real-time monitoring of patients' cardiovascular health. This limitation makes it extremely difficult for healthcare providers to identify warning signs early enough to …
Published in Journal of Telecommunication, Switching Systems and Networks · Vol. 12, Issue 2, 2025 · pp. 1–5 Read article
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Molecular Docking of Arjuna Tree Phytocompounds for Ischemic Heart Disease
Abstract: Heart disease is a serious condition that can be caused by several lifestyle changes and sometimes genetic problems. The primary protein component of apolipoprotein is the LDL receptor, which indicates that a reduction in LDL levels can reduce the risk of ischemic heart disease. Apolipoprotein levels are associated with increased levels of ischemic heart disease. Using ADMET analysis, drug likelihood prediction, and molecular docking, this work attempted to find natural …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 42–52 Read article
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Risk Management in Civil Engineering by FTA, FMEA and Risk Matrix
Abstract: Infrastructure projects, particularly in civil engineering, are fraught with uncertainties that manifest as both physical and financial risks. The project report, titled Quantifying and Managing Financial and Physical Risks in Infrastructure Projects, aims to bridge the existing gap between managing these two critical categories of risks. By integrating advanced statistical methodologies such as Failure Mode and Effects Analysis (FMEA), Fault Tree Analysis (FTA), Risk Matrix, and Regression Analysis, this study …
Published in Journal of Structural Engineering and Management · Vol. 12, Issue 1, 2025 · pp. 34–46 Read article
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Innovations in Oral Drug Delivery: Challenges and Opportunities
Abstract: The advancement of novel drug manufacturing technologies offers immense opportunities for innovation but brings regulatory complexities that must be addressed to ensure successful implementation. Early and frequent collaboration with the FDA is fundamental for overcoming these challenges. The establishment of the FDA’s Emerging Technology Team has been pivotal in fostering open dialogue, brainstorming, and feedback between regulators and innovators, reducing the likelihood of unexpected setbacks that could jeopardize projects. Mechanisms …
Published in Trends in Drug Delivery · Vol. 12, Issue 1, 2025 · pp. 31–43 Read article
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A Literature Review on Extrusion/Spheronisation-A Pelletization Technology
Abstract: Extrusion-spheronization is a leading pelletization technology, widely favored for its economic and commercial viability. It is a cost-effective method suitable for large-scale production, making it the most efficient approach for oral drug delivery. This process provides multiple benefits, such as improved flow characteristics, lower friability, a narrow particle size range, easier coating, consistent packing, reduced likelihood of dose dumping, and more predictable gastric emptying. Pellets usually measure between 0.5 and …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 61–71 Read article
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What Is the Meaning and Purpose of Risk Management in Cyber Security?
Abstract: Organizations and their information systems are increasingly exposed to risk and uncertainty from a variety of sources, including computer fraud, espionage, and sabotage or cyber-attacks. The purpose of this article is to outline several steps, protocols, and factors that any organization should consider in the event of a cyber-attack. Over time, some damage causes, including denial of service or intrusion attacks, have grown more frequent, aggressive, and complex. Complete security …
Published in International Journal of Information Security Engineering · Vol. 3, Issue 1, 2025 · pp. 46–53 Read article
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Computational Investigation of Phytochemicals Targeting AKT1 for Major Depressive Disorder: A Molecular Docking and ADMET Study
Abstract: Major depressive disorder (MDD) is a prevalent neuropsychiatric condition affecting approximately 280 million individuals worldwide, with women exhibiting a 50% higher likelihood of diagnosis than men. Despite significant advancements in treatment, MDD remains a chronic and relapsing disorder, necessitating the exploration of novel therapeutic interventions. This study focuses on the AKT1 gene, a key player in neuropsychiatric disorders, and investigates its interactions with natural phytochemicals as potential alternatives to conventional …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 2, 2025 Read article
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Breaking the Cycle: The Impact of Hygiene Deficiencies on the Health of the Poor
Abstract: Poor sanitation and hygiene present significant health risks, particularly for individuals in low- income communities. Inadequate sanitation systems increase the likelihood of exposure to harmful microorganisms found in contaminated water, food, and environments. This exposure contributes to the spread of waterborne diseases such as cholera, dysentery, and typhoid, along with various gastrointestinal illnesses. Limited access to clean water and soap for handwashing exacerbates these risks, particularly for children, who are …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 22–39 Read article
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Role of Dermabrasion Assisted Tangential Excision in Paediatric Electrical Burn Wounds
Abstract: Early removal of necrotic tissue in deep electrical burns by tangential excision decreases scarring and promotes wound healing. Dermabrasion, traditionally used in dermatology for facial resurfacing and scar treatment, has shown promising results when applied to burn wound management. In burn care, dermabrasion serves as a form of blunt debridement, effectively removing superficial necrotic tissue without damaging underlying healthy structures. This technique helps reduce local inflammation and lowers the likelihood …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 2, 2025 Read article
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Modeling Dispersed Count Data: Evaluating the Conway–Maxwell–Poisson Regression with COVID-19 Mortality Data
Abstract: Count data are prevalent in diverse fields such as biology, healthcare, psychology, and marketing, characterized by non-negativity and inherent heteroskedasticity, often exhibiting overdispersion or underdispersion. Traditional Poisson regression, which assumes equal mean and variance, is inadequate for such dispersed data. To address this, various generalized linear models (GLMs) and their extensions, including negative binomial (NB) and Conway–Maxwell–Poisson (CMP) regressions, are utilized. This study evaluates the performance of CMP regression compared …
Published in Research & Reviews : Journal of Statistics · Vol. 13, Issue 3, 2024 · pp. 18–26 Read article
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Review on Hair Cosmetics on Flaxseeds
Abstract: Worldwide cultivation of flaxseed (Linum usitatissimum), a significant medicinal oil seed crop, is practiced. Flaxseed belongs to the Linaceae family.Because of its biologically active components, which include lignans, dietary fiber, and alpha-linolenic acid, flaxseed has garnered interest as a functional food ingredient recently.Worldwide, Flaxseed is cultivated not only for its oil and fiber but also for its nutritional and potential therapeutic benefits. The dietary fiber present in flaxseed supports overall …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 2, 2025 · pp. 38–46 Read article
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Cervical Cancer: Understanding Its Causes, Risk Factors, and Preventive Measures
Abstract: Cervical cancer is a form of cancer that begins in the cervix, the lower portion of the uterus, due to abnormal cell growth that can spread or invade other areas of the body. In its early stages, cervical cancer usually shows no obvious symptoms, which is why regular screenings are essential for detecting it early. As the cancer advances, symptoms such as pelvic pain, unusual vaginal bleeding, and pain during …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 26–30 Read article
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Excessive screen time: Understanding its long-term impact on health and behavior
Abstract: In today’s world, digital gadgets, like laptops, game consoles, smartphones, and televisions, are essential since they provide entertainment and convenience. However, their overuse has raised serious concerns regarding long-term health and social implications. This review investigates the extensive effects of excessive screen time on mental, physical, and social well-being, with a special emphasis on children and adolescents. The growing amount of time toddlers and preschoolers spend in front of screens …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 2, 2025 · pp. 13–21 Read article
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Automatic Brake Failure Indication with Auxiliary Braking System
Abstract: Accidents in vehicles often happen due to diverse factors, with brake failure being a significant contributor resulting from inadequate maintenance and product defects. To protect human lives and reduce the risk of accidents, effective monitoring of brake systems is vital in the automotive industry. Vehicle safety encompasses not only the prevention of accidents but also the mitigation of their adverse effects on human health. Today’s cars come with innovative safety …
Published in Journal of Automobile Engineering and Applications · Vol. 12, Issue 2, 2025 · pp. 1–7 Read article
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Pharmacology in Clinical and Therapeutic Settings
Abstract: Polypharmacy, which refers to the practice of taking many medications at the same time, is becoming more common among elderly populations as a result of the steadily increasing prevalence of chronic conditions. The clinical and therapeutic consequences of polypharmacy are investigated in this paper, with a particular emphasis placed on drug-drug interactions, altered pharmacokinetics, and patient safety. The physiological changes that occur with advancing age have a substantial impact on …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 51–58 Read article
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Role of Food Supplements in Premalignant Lesions: A Literature Review
Abstract: Premalignant lesions of the oral cavity are histopathological alterations in the oral epithelium linked to a higher likelihood of malignant transformation. These lesions frequently present as leukoplakia (white patches), erythroplakia (red patches), oral lichen planus, and oral submucous fibrosis. Oral cancer, categorized among head and neck malignancies, is considered the sixth most common cancer globally. While tobacco and alcohol consumption remain the primary etiological factors, increasing evidence underscores the significant …
Published in Research and Reviews: A Journal of Dentistry · Vol. 16, Issue 3, 2025 · pp. 17–26 Read article
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Artificial Intelligence in Diagnostics: Advancements, Challenges, and Future Prospects
Abstract: AI is changing (and will change) healthcare as we know it, and diagnostics might be the specialty that feels the most discomfort. Artificial intelligence-based analytical systems are facilitating the detection, diagnosis, and treatment of a variety of diseases, with better accuracy, speed, and results. Now, this abstract investigates the role of AI in diagnostics, scouring its elements, landmark techniques, transformative impact and future overview. This article explains AI and discusses …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 3, 2025 · pp. 8–17 Read article
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Gear-Related Stress Analysis and Comparison Between the Fem and Agma Standards
Abstract: In many different devices, gears enable the efficient transfer of motion and torque. They are an essential component of modern mechanical power transmission systems. It has been demonstrated that bending and surface contact stresses at the gear tooth are the primary causes of gear failure, despite their widespread use. Too much stress can lead to tooth wear, pitting, or breakage, which can ultimately reduce the operating life and reliability of …
Published in Trends in Mechanical Engineering & Technology · Vol. 15, Issue 3, 2025 · pp. 13–18 Read article