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100 articles for “Tuberculosis Tuberculosis”
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In silico Molecular Docking Analysis of Stephania glabra phytocompounds Targeting Thymidylate Kinase for potential Antituberculosis Activity
Abstract: Tuberculosis (TB) is an infectious disease caused by the bacteria Mycobacterium tuberculosis. It mainly affects the lungs and spreads through the air when a person with active TB in their lungs coughs, sneezes, or spits. This study investigates several bioactive compounds derived from plants to forecast how effective plant-based ligands will be at preventing tuberculosis. The purpose of the study was to use computational techniques to assess the effectiveness of …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 · pp. 25–37 Read article
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Prediction of the Natural Progression of Tuberculosis using Markov Model
Abstract: This study was done to find out the natural development of the tuberculosis (TB) patients. It was an observational study conducted between years 2013 and 2015 at 200 patients with TB. 150 patients entered the regular treatment of dot course and the remaining patients entered the irregular treatment of Dot course. The stage of the patient was noted at the end of the every year and transition matrices were applied …
Published in Research & Reviews : Journal of Statistics · Vol. 7, Issue 3, 2018 · pp. 7–11 Read article
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Aetiology of Ascites and Diagnostic Value of Ascitic Fluid Analysis
Abstract: Ascites is an important feature of many diseases, mainly liver disorder. The aim of this study is to determine the causes of ascites in Nagpur region, and to evaluate the significance of ascitic fluid analysis in different types of ascites.This prospective study was conducted at Govt. Medical College Nagpur. It involved patients admitted with primary diagnosis of ascites, over a period of 1 year, (may 2007-may 2008). The total number …
Published in Research and Reviews: A Journal of Medicine · Vol. 1, Issue 1, 2011 · pp. 25–33 Read article
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Molecular Docking Studies for the Identification of Mycobacterial Adenosine Triphosphate (ATP) Synthase Inhibitors Using Active Phytocompounds from Plants Curcuma longa, Curcuma zedoaria and Galipea officinalis
Abstract: Objective: Tuberculosis (TB), known in human history for several decades, remains the second leading infectious disease after COVID-19. Still, the occurrence of TB increases due to the bacterium’s greater survival nature. They can survive in extreme conditions by being in long latency and adapting to the host. This study seeks to identify potential inhibitors from Curcuma longa, Curcuma zeodaria, and Galipea officinalis based on ancient folklore and compare them against …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 16–26 Read article
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Bedaquiline: An In-Depth Exploration into Its Antitubercular Significance
Abstract: Tuberculosis is still a leading infectious disease and a major threat to public health. Although there has been a slow decrease in the incidence over years, its “hard to kill nature” is responsible of about 2 million deaths in HIV infected individuals annually. Bedaquiline, a Diaryl-Quinoline drug was fast-track approved as an orphan drug to combat drug resistance. It shows potent activity against Mycobacterium tuberculosis by interfering with the production …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 06–14 Read article
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A Study to Assess the Knowledge and Practice Regarding Prevention of TB Among Staff Nurses Working in a Selected TB Hospital at Jodhpur
Abstract: Tuberculosis (TB) remains a major global public health concern, causing significant morbidity and mortality, particularly among healthcare workers. Staff nurses are at heightened risk due to repeated exposure to patients with active TB, making knowledge and adherence to preventive practices critical. The present study was conducted to evaluate the knowledge and practices of staff nurses concerning tuberculosis (TB) prevention at Kamla Nehru TB and Chest Hospital, Jodhpur. A descriptive and …
Published in International Journal of Community Health Nursing And Practices · Vol. 4, Issue 1, 2026 · pp. 7–33 Read article
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KNOWLEDGE ON PREVENTION AND MANAGEMENT OF PULMONARY TB AMONG NURSING STUDENTS
Abstract: Background: According to annual global Tuberculosis report 2015 published by WHO; globally, Tuberculosis prevalence in 2015 was 42% lower than in 1990. India (23%), Indonesia (10%), China (10%) had the largest number of cases of the global total respectively India accounts for 27% of global Tuberculosis notification in 2014. At any given point of time, there are 4 million infectious cases in India. Tuberculoses is silently killing approximately more than …
Published in Research and Reviews: A Journal of Medicine · Vol. 7, Issue 2, 2017 · pp. 21–25 Read article
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Drug-Resistant TB—Problem and Management: a Review
Abstract: Tuberculosis (TB) is one of the oldest diseases known to affect humans. TB is a major cause of death worldwide. The bacteria Mycobacterium tuberculosis is the causative agent of TB. It usually affects the lungs and causes pulmonary TB. The intestine, meninges, bones, joints, lymph glands, skin and other tissues of the body are also affected. TB caused by drug-susceptible strains is curable in virtually all the cases after proper …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 6, Issue 3, 2019 · pp. 30–34 Read article
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Pneumonia Identification Using Explainable Artificial Intelligence
Abstract: Pneumonia, including tuberculosis (TB), remains one of the leading causes of death worldwide, especially in regions where access to healthcare is limited. Early and accurate diagnosis is critical for effective treatment and better patient outcomes, but traditional methods are time-consuming and require specialized expertise. This study explores the use of advanced deep learning models VGG16, VGG19, and ResNet50 to detect pneumonia and TB from chest X-ray images. By leveraging transfer …
Published in Journal of Advanced Database Management & Systems · Vol. 12, Issue 3, 2025 · pp. 01–11 Read article
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Operational Research—Tuberculosis Overview
Abstract: The present review outlined the basic information regarding operational research for successful control of communicable diseases in India with its history of origin, objectives, scope, basic approaches, steps, and principles involved. Also the descriptive critical review on burden of communicable diseases such as tuberculosis and COVID-19 burden in India along with present scenario and problems being faced by India over control of communicable diseases in 2020 were also discussed. The …
Published in Research and Reviews: A Journal of Medicine · Vol. 13, Issue 1, 2023 · pp. 15–20 Read article
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A Literature Survey on Biological Activities of Thiazolidine Derivatives
Abstract: Hetercyclic compounds play a vital role in both chemical and life sciences. Among them ,thiazolidinone represent a significant class, characterized by a five- membered saturated ring containing both sulfur and nitrogen atoms. Structurally, thiazolidinones are derived from thiazole, with sulfur position at the 1-position, nitrogen at the 3-position , and a carbonyl group typically located at the 2-, 4-, or 5- position are possible, though structural and functional diversity is …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 16–21 Read article
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Pharmacophore mapping, 3D QSAR, docking, and ADME prediction studies of novel Benzothiazinone derivatives
Abstract: Background Tuberculosis is a major public health concern worldwide which is caused by Mycobacterium tuberculosis. DprE1 (Decaprenyl Phosphoryl Ribose 2’- Epimerase) is the most challenging target for development of novel anti- tubercular agents because it is a small protein and located into cytoplasmic membrane. So, novel anti-TB drugs did not bound effectively with it. DprE1 catalyzes the oxidation of the 2’ hydroxyl group of DPR (Decaprenyl Phosphoryl D- Ribose) …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 59–82 Read article
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Innovative Vaccine Technologies: Current Landscape and Future Prospects in Preventive Medicine
Abstract: This review article presents a comprehensive analysis of recent advancements and emerging trends in vaccine development, offering insights into the dynamic landscape of preventive medicine. Delving into a spectrum of infectious diseases, including influenza, HIV/AIDS, malaria, tuberculosis, respiratory syncytial virus (RSV), Group B Streptococcus (GBS), norovirus, and chikungunya, the review highlights innovative approaches and breakthroughs in vaccine technology. It explores efforts to develop universal influenza vaccines, long-awaited HIV vaccines, and …
Published in International Journal of Vaccines · Vol. 1, Issue 2, 2024 · pp. 07–15 Read article
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Breakthroughs in Biotechnology for the Regulation of Infectious Diseases
Abstract: Infectious diseases have a heavy impact on both public health and the world’s economies. In most diseases, antibiotic resistance has become widespread over time. A variety of diseases comprising pneumonia, tuberculosis, and gonorrhea go through the same evolutionary processes, which include the formation of drug-resistant pathogens in response to selection pressure from medications and their potential extinction when drug use is ceased. Since the occurrence of drug resistance in serious …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 1, 2025 · pp. 1–25 Read article
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Survey in Hydrazine and its Preparation, Reactions, and Their Applications
Abstract: This review concerned with hydrazine derivatives; Hydrazine is an important chemical compound used in jet engine and rocket fuel. Therefore, the European Union prohibits its sales to the developing world at 100% concentration and only permits its sales at 20-25% concentration. It is also used in industry to produce chemicals for textiles, agriculture, photographic development materials, and blowing agents used in the manufacture of foam rubber. It is also used …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 1, 2026 · pp. 27–34 Read article
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Incidence of Scrofula in Enlarged Neck Nodes
Abstract: To determine the incidence of scrofula (tubercular lymphadenitis) in enlarged neck nodes, prospective study is carried out in the Department of General Surgery, NIMS Medical College, Jaipur for three years from June 2011 to May 2014. The study included a group of 130 patients with cervical lymphadenopathy. All patients were clinically examined and investigated thoroughly. CBC, ESR, X-ray chest and Montoux’s test were performed. Fine Needle Aspiration Cytology (FNAC) and …
Published in Research and Reviews : Journal of Surgery · Vol. 3, Issue 3, 2014 · pp. 5–8 Read article
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Prevalence of HIV and TB Co-infection: Mumbai Scenario
Abstract: HIV, being the most powerful risk factor, has made the reappearance and progression of tuberculosis easier. The partnership of HIV and TB is a major health problem in both developed and developing countries. The present study was undertaken in Mumbai to study the prevalence of HIV and TB coinfection in patients who visited the tertiary care centers in the city. Both HIV and TB were diagnosed using nucleic acid amplification …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 3, Issue 2, 2013 · pp. 26–32 Read article
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Isolation and Characterization of Lantibiotic Producing Lactic Acid Bacteria from Ambali, Aged Mango Pickle Probiotics
Abstract: Each year in the US at least 2 million people are sickened with antibiotic resistant infection. The development of antibiotics was one of the most important advances of medicine. Many bacterial infections (e.g. tuberculosis and infected wounds) that previously had no effective treatment and often killed people became treatable with antibiotics, saving millions of lives. Now, because of the overuse and misuse of antibiotics, bacterial infections that were once easily …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 3, Issue 3, 2016 · pp. 30–36 Read article
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DESIGNING OF COUMARIN ANALOGS: A NEW INSIGHT AS ENOL ACYL CARRIER PROTEIN REDUCATSE INHIBITORS
Abstract: Tuberculosis was almost certainly the leading cause of death in Europe and the United States in recorded history, although because of the multifarious forms of the disease. Based on literature we have designed coumarin linked with thiadiazole derivatives as antitubercular agents. To determine structural requirements, we carried out molecular docking study in which we found that our designed molecule have similar binding with enoyl acyl carrier protein reductase (InhA). The …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 6, Issue 2, 2019 · pp. 1–5 Read article
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Overview On Lauha Rasayana W.S.R. To Rasayogasagar
Abstract: Ayurved is the ancient science which addresses disorders with the natural pharmaceuticals, including those derived from animals, plants, minerals and metals. Rasashastra is a pharmaceutical branch of Ayurved medicine, which developed in mediaeval period and focuses on therapeutic use of metals and minerals. Treatment with using of this metals, minerals, gemstones, animal product and herbal ingredients is known as Rasachikitsa. The key objective of Rasachikitsa is to deliver high-quality, safe …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 1, 2024 · pp. 11–16 Read article