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110 articles for “Medicines”
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A Review of Drug Design Techniques Assisted by Computers to Combat Diabetes
Abstract: Diabetes mellitus is a global health concern characterized by chronic hyperglycemia and associated complications. The creation of innovative medicines with enhanced efficacy and safety profiles continues to be a top focus, notwithstanding improvements in treatment. A useful method in drug development, computer-aided drug design (CADD) makes it easier to identify possible therapeutic candidates and optimise lead molecules. An extensive synopsis of CADD tactics used in the fight against diabetes is …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 1–10 Read article
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Lifestyle Factors and Perceptions of Diabetes Among Individuals in North India
Abstract: Background: Diabetes mellitus is influenced by a complex interplay of genetic, environmental, and lifestyle factors. In North India, unique socio-cultural and dietary patterns shape individual behaviors and perceptions toward diabetes. Understanding these lifestyle choices and cultural beliefs is critical for designing interventions that improve adherence to medical treatment and promote healthier outcomes. Methods: A cross-sectional survey was conducted among 1,500 individuals diagnosed with diabetes across selected urban and rural districts …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 2, 2025 · pp. 1–7 Read article
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Personalized Therapy Using Drug Delivery Devices
Abstract: The persistent challenge in modern medicine lies in inter-patient heterogeneity, rendering standardized drug dosing protocols suboptimal for many chronic conditions. Traditional pharmacokinetics fail to account for real-time biological fluctuations, leading to cycles of ineffective treatment or dose-limiting toxicity. This paper explores the critical intersection of advanced drug delivery devices (DDDs) and personalized medicine, positioning these technologies as the vital link translating genomic and biological data into tangible, patient- specific interventions. …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 53–62 Read article
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The Heat of Competition: Assessing Climate Vulnerabilities and Adaptive Governance in Endurance, Winter, and Youth Sports
Abstract: Background: Climate change is fundamentally reshaping the environmental parameters of global sport, posing unprecedented risks to athlete health, safety, and performance. As rising temperatures, frequent extreme heat events, and deteriorating air quality become the new normal, athletic environments from community fields to elite international arenas face an existential threat. Purpose: This study provides an interdisciplinary synthesis of the multifaceted impacts of climate change on athletes, integrating evidence from sports medicine, …
Published in International Journal of Climate Conditions · Vol. 2, Issue 2, 2025 · pp. 9–17 Read article
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Exploring the properties and extraction of neem leaves
Abstract: Neem (Azadirachta indica) is a versatile medicinal plant, for its diverse therapeutic properties. This abstract provides a comprehensive overview of recent research focusing on phytochemical analysis, biochemical characterization, and antimicrobial susceptibility testing of Neem extracts. Utilizing the different from of chemical used in it, phytochemical analysis identified a plethora of secondary metabolites within Neem, including alkaloids, flavonoids, terpenoids, steroids, saponin, tannins, quinone, and phenolic compounds, indicative of its complex chemical …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 2, 2024 · pp. 32–39 Read article
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Horizon Scanning and Early Assessment of Health Technologies for the Treatment of Orphan Diseases
Abstract: The theoretical foundations and regulatory framework of the processes of the formation of an effective health technology assessment (HTA) system at the early stages of the life cycle of medicines are analyzed in the article. Particular attention is paid to horizon scanning (HS) and early assessment of expensive innovative drugs utilized for treating rare diseases. In order to inform policymakers, purchasers, and providers (to prioritize MT research, financial, and operational …
Published in International Journal of Brain Sciences · Vol. 1, Issue 1, 2024 · pp. 32–39 Read article
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Comprehensive Approaches to Understanding and Managing Alzheimer’s Disease
Abstract: Alzheimer’s disease is an advanced neurodegenerative disorder described by intense memory loss. It strictly affects the patient’s quality life. The popularity of AD has been increasing in recent years. It is the most common form of mental disorder affecting more than 20 million people in the world. The Alzheimer’s disease is treated with cholinesterase inhibitors or NMDA-receptor (N-methyl D-aspartate) antagonists but here the question is about the therapeutic effect of …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 1–9 Read article
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Bio-Inspired Membranes in Oral Drug Delivery: A Pathway to Enhanced Permeability and Targeted Therapy
Abstract: Bio-inspired membranes in oral drug delivery represent a significant advancement in pharmaceutical technology, harnessing principles of natural biological systems to improve drug permeability, bioavailability, and targeted release. This review discusses the design, materials, and fabrication techniques used in bio-inspired membranes, with a focus on materials like chitosan, silk fibroin, and synthetic polymers that mimic biological structures. By exploring the mechanisms of drug permeation, such as mucoadhesion and selective permeability, bio-inspired …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 39–52 Read article
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Acupuncture in Pain Management: A Neurophysiological and Clinical Perspective
Abstract: Acupuncture, a key component of traditional Chinese medicine, has gained widespread recognition as an alternative therapy for pain management. This practice involves the insertion of fine needles into specific points on the body to influence the flow of energy or "Qi" (pronounced "chee") and restore balance. Mechanistically, acupuncture is believed to modulate pain through neurophysiological pathways, including the release of endorphins, the activation of the body's natural analgesic systems, and …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 Read article
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Quinine: Past, Present, and Future Perspective in Malaria and Autoimmune Disorder
Abstract: Quinine, a natural alkaloid extracted from the bark of the cinchona tree, has traditionally played a key role in treating malaria, a disease caused by parasites of the Plasmodium genus. Since its discovery in the 17th century, quinine has evolved from a rudimentary treatment to an essential component of modern antimalarial therapies. This article explores the historical use of quinine in the fight against malaria, its role in current treatment …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 24–33 Read article
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Rosemary: A Natural Way to Improve Brain Health and Cognitive Function
Abstract: Cognitive decline is a common consequence of aging, often leading to diminished quality of life. Although conventional drug treatments, such as anticholinesterase inhibitors, are available for managing cognitive decline, they are not always effective in older adults and may even induce adverse effects. As a result, there has been growing interest in natural alternatives, particularly traditional herbal medicines, for their potential cognitive-enhancing properties. Among these, Rosmarinus officinalis (Rosemary) has gained …
Published in International Journal of Brain Sciences · Vol. 2, Issue 1, 2025 · pp. 30–36 Read article
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Drug Induced Immune Mediated Nephritis: Molecular Mechanism , Pathways and Clinical Implications
Abstract: Drug-induced immune-mediated nephritis (DI-IMN) has become a more widely known cause of acute kidney injury (AKI), with the potential for development to chronic kidney disease if not detected and treated promptly. T-cell hypersensitivity to pharmaceuticals, such as antibiotics, proton pump inhibitors, nonsteroidal anti-inflammatory drugs, and immunological drugs, are the major causes for it. Beyond clinical burden, DI-IMN reflectsintricate molecular interactions that sustain interstitial inflammation and tubular injury. These interactions include …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 13–29 Read article
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Plant-Derived Psychotropic Agents Targeting Neurotransmitter Systems: Pharmacognostic Evidence, Mechanisms, and Clinical Relevance
Abstract: Psychiatric health problems are also a large burden on global health and existing psychotropic drugs may be restricted by relative effectiveness, side effects, and inadequate long-term tolerability. Plant- based psychotropic agents have subsequently been the focus of interest in the form of complementary or alternative therapies. This review outlines the pharmacognostic, mechanisms of action and therapeutic importance of plant-based psychotropic agents against central neurotransmitter systems. The traditional medicinal practices give …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 · pp. 34–42 Read article
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Infectious Diseases: Current Epidemiology, Pharmacotherapeutic Strategies, and Global Health Perspectives
Abstract: Infectious diseases are still a major health challenge in the world, and there is increased strain on the health systems of nations. This review examines the most important issues in the management of infectious diseases, such as the distribution and effect of infectious diseases across the world, pharmacotherapeutic approaches, and the functions of public health interventions. New threats such as antimicrobial resistance (AMR), the contribution of climate change, and the …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 1, 2026 · pp. 10–18 Read article
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The Parasitic Fingerprint: Tracing Infection to Host Illness
Abstract: Parasitic infections remain a major global health burden, causing significant morbidity and mortality, particularly in tropical and subtropical regions. A critical aspect of disease pathogenesis is the unique molecular and cellular imprint left by parasites in their hosts, termed the “parasitic fingerprint.” These fingerprints encompass parasite-derived proteins, nucleic acids, metabolites, extracellular vesicles, and host responses, including gene expression changes, cytokine profiles, and metabolic adaptations. Advances in multi-omics technologies, which integrate …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 1, 2026 · pp. 29–50 Read article
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Artificial Intelligence in Early Diagnosis and Personalized Treatment of Alzheimer’s Disease
Abstract: Artificial intelligence (AI) has become a disruptive technology in the medical care industry, with potential solutions to early diagnosis and customized treatment of Alzheimer’s disease (AD), a progressive neurodegenerative disease and the most prevalent cause of dementia globally. Conventional diagnostic techniques, such as cognitive, neuroimaging and biomarker techniques, are usually limited in the ability to detect disease at its most susceptible stage when treatment interventions are most effective. The recent …
Published in International Journal of Brain Sciences · Vol. 3, Issue 2, 2026 · pp. 15–27 Read article
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Evolving IoT: Based Smart Healthcare Monitoring System
Abstract: The continuous progress in technology has led to remarkable enhancements in various aspects of human life, including healthcare. Within the healthcare sector, practitioners and experts are embracing new technologies to significantly improve the implementation of medical services. The Internet of Things (IoT) has emerged as a crucial foundation for various innovative healthcare technologies, such as heartbeat sensors, ECGs, and blood pressure sensors, each equipped with microcontrollers to read and interpret …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 1, Issue 1, 2024 · pp. 17–27 Read article
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Nutraceutics: Opening the Debate for a Framework for the Safety and Efficacy of Nutraceuticals Formulations
Abstract: As of right now, there is no precise definition for nutraceuticals that distinguishes them from other food-based categories such herbal products, dietary supplements, pre- and probiotics, functional foods, and fortified foods. Several studies have shed light on the possible mechanisms of action of pharmaceutically active ingredients in food, emphasizing their ability to improve health, lower the risk of disease, and promote general wellbeing. However, Nutraceuticals confront difficulties in substantiating safety …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 1, 2024 · pp. 27–33 Read article
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Secondary Metabolites in Drug Development: Tracing Their Historical and Therapeutic Impact
Abstract: Secondary metabolites, also known as natural products, exhibit a level of structural and chemical diversity unmatched by synthetic small molecule libraries. These compounds, which have evolved to possess drug-like properties, continue to be a primary source for new medications and drug leads. Their discovery has significantly impacted advancements in chemistry, biology, and medicine, influencing drug development and therapeutic strategies throughout history. Derived from primary metabolic pathways such as photosynthesis, glycolysis, …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 51–55 Read article
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The Power of Genetic Engineering in Revolutionizing Vaccines
Abstract: Genetic engineering techniques, including recombinant subunit, viral vector, and nucleic acid vaccines have transformed the landscape of vaccine development. These novel approaches offer precise antigen design, enhanced safety profiles, and rapid adaptability to emerging pathogens. Key advantages include improved efficacy through targeted immune responses, increased safety due to the absence of live pathogens, and the ability to modify vaccines to address new variants or diseases quickly. Notable success stories, such …
Published in International Journal of Vaccines · Vol. 2, Issue 1, 2025 · pp. 18–27 Read article