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103 articles for “Mechanisation”
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HPV and Cardiovascular Risk: Unpacking a Novel Link Between Viral Infection and Heart Disease
Abstract: Human papillomavirus (HPV) is best known for its oncogenic potential, yet a growing body of evidence suggests that persistent HPV infection may also contribute to cardiovascular disease (CVD). In 2025, pooled analyses and conference reports galvanized attention by estimating that HPV‐positive individuals have ~40% higher risk of CVD and approximately double the risk of coronary artery disease (CAD) compared with HPV‐negative peers, even after adjustment for traditional risk factors. These …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 1–5 Read article
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Integrated Optimization of Solar Photovoltaic Systems Using Taguchi Method and Computational Fluid Dynamics for Enhanced Efficiency
Abstract: The transition to renewable energy demands efficient and reliable photovoltaic (PV) systems to meet rising global energy needs. This study presents an integrated optimization framework combining the Taguchi method and Computational Fluid Dynamics (CFD) to improve the thermal and electrical performance of solar PV systems. A structured experimental design using an L9 orthogonal array evaluates the influence of three key parameters—material type, panel thickness, and cooling mechanism—on system efficiency. Analysis …
Published in Recent Trends in Fluid Mechanics · Vol. 12, Issue 3, 2025 · pp. 10–25 Read article
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Comprehensive Review on Pulsatile Drug Delivery System: Hybrid Approaches
Abstract: Pulsatile drug delivery systems (PDDS) represent a groundbreaking approach in pharmaceutical technology, allowing for controlled, targeted, and programmable drug release that aligns with circadian rhythms or caters to time-sensitive therapeutic requirements. Although traditional pulsatile systems have shown considerable clinical promise, their effectiveness is frequently compromised by physiological variations such as gastrointestinal transit times, changes in pH, and enzymatic activity. To tackle these obstacles, hybrid PDDS have been developed by combining …
Published in Trends in Drug Delivery · Vol. 13, Issue 1, 2026 · pp. 18–31 Read article
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Physics, Metaphysics, and the Subtle Sciences: A Dialogue between Indigenous Worldviews and Microvita Theory
Abstract: This paper explores the convergence of physics, metaphysics, and subtle sciences through a comparative analysis of indigenous knowledge systems and P.R. Sarkar’s Microvita Theory. Indigenous worldviews across various cultures articulate a holistic understanding of reality in which consciousness, matter, and life processes are deeply interconnected. These frameworks increasingly resonate with developments in quantum physics and systems theory that challenge classical mechanistic paradigms. Microvita Theory, introduced by P.R. Sarkar, posits the …
Published in Research & Reviews : Journal of Physics · Vol. 15, Issue 1, 2026 · pp. 1–13 Read article
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Histological Effects of the Antibiotic Gentamicin on the Ovarian Tissue of Female White Laboratory Rats
Abstract: This study aimed to evaluate the histological alterations induced by Gentamicin in the ovarian tissue of white laboratory rats. A total of 12 adult female rats were used and randomly divided into two groups, with each group consisting of six animals. The experimental group received Gentamicin at a dose of 120 mg/kg body weight administered as an injection once daily, while the control group received an equivalent volume of normal …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 1–8 Read article
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Using Machine Learning to Guess Photochemical Reaction Pathways
Abstract: Photochemical reactions are crucial to many activities in the fields of energy conversion, environmental cleanup, and synthetic chemistry. However, predicting their causes and results effectively is still very hard since they entail excited electronic states, nonadiabatic transitions, and complicated potential energy surfaces. Machine learning (ML) has been a powerful technique to go along with classic quantum chemistry methods in the last few years. It offers better prediction capability and lower …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 3, Issue 2, 2025 · pp. 01–12 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Sustainable Biomedical Applications
Abstract: Liposomal drug delivery has evolved into a viable approach in modern pharmacology thanks to its enhanced bioavailability, reduced systemic toxicity, and targeted drug release. Conventional liposomes have limited stability, medicine leakage, and short circulation times among other problems. Overcoming these limits, the inclusion of nano-polymers into liposomal formulations has transformed medication delivery. Thorough research has been done on the potential of nano-polymers including chitosan, hyaluronic acid, polyethylene glycol (PEG), and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 420–432 Read article
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Land Tenure, Farming Constraints, and Rural Livelihoods in India: An Integrated Assessment
Abstract: Land remains the central asset shaping agricultural productivity, socio-economic security, and rural development in India. However, the complex interaction between land tenure systems, farming challenges, and livelihood patterns continues to hinder sustainable agricultural growth. This review provides an integrated assessment of the key issues influencing land use dynamics, including ownership inequalities, insecure tenancy arrangements, land fragmentation, and the slow implementation of land reforms. These structural limitations restrict farmers’ access to …
Published in International Journal of Land · Vol. 2, Issue 2, 2025 · pp. 11–16 Read article
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Development of a Durable Superhydrophobic EP/PDMS Coating Reinforced with Micro-CaCO₃ and Nano-ZnO for Enhanced Corrosion Protection and Multifunctional Performance on Carbon Steel
Abstract: Balancing exceptional multifunctional performance with mechanical robustness in micro-nano composite films remains a significant challenge for practical applications. In this work, a superhydrophobic coating reinforced with micro-CaCO₃ and nano-ZnO particles was fabricated through a versatile single-step brushing method. The optimized EP/PDMS@micro-CaCO₃/nano-ZnO coating achieved a water contact angle (WCA) of 173.54° ± 2.53° and a sliding angle (SA) of 1.50° ± 1.12°. Owing to its carefully engineered micro-nano hierarchical structure, the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 216–238 Read article
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Interfacial and Tribo-Mechanical Performance of a TiO₂–Castor Oil Polymeric Nanofluid During Sustainable Machining of AISI 316L Stainless Steel Under MQL Conditions
Abstract: This research examines the tribo-mechanical performance and interfacial film characteristics of a TiO₂-reinforced castor-oil polymeric nanofluid during the turning of AISI 316L stainless steel under minimum-quantity lubrication (MQL). A Taguchi L9 orthogonal array was utilized to assess the synergistic effects of cutting speed, depth of cut, and coolant composition on surface integrity, while machining experiments were performed under dry, conventional, and TiO₂-nanofluid lubrication techniques. ANOVA and multiple-regression modeling were used …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 901–914 Read article
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Nutrition Induced Gut Microbiota Modulation in Food Animals: Implications for Viral Susceptibility, Shedding and Transmission Dynamics for Sustainable Development
Abstract: The gut microbiota has emerged as a central mediator linking host nutrition, immune competence, and vulnerability to viral pathogens in food animals. Diet is a primary driver of microbial community structure and function, influencing metabolite production, intestinal barrier integrity, and systemic antiviral immunity. Accumulating evidence indicates that nutrition induced modulation of the gut microbiota can substantially alter viral susceptibility, replication, and shedding patterns, with downstream effects on transmission dynamics within …
Published in International Journal of Virus Studies · Vol. 3, Issue 1, 2026 · pp. 46–56 Read article
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Nutrition Induced Remodeling Dynamics of Cell Membranes: Implications for Performance, Health, and Welfare Issues in Food Animals
Abstract: Cell membranes represent dynamic structural and functional platforms that integrate nutritional signals with cellular metabolism, immune competence, and physiological adaptation in food animals. Beyond their classical role as selective barriers, membranes actively regulate nutrient transport, signal transduction, and bioenergetics through highly responsive lipid and protein networks. Dietary components, particularly fatty acids, vitamins, minerals, amino acids, and bioactive compounds, critically influence membrane composition, fluidity, and stability, thereby shaping cellular function and …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 25–37 Read article
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SUSTAINABLE MEMBRANE FABRICATION USING GREEN CHEMISTRY PRINCIPLES: A COMPREHENSIVE REVIEW OF MICROWAVE IRRADIATION, SONOCHEMICAL, AND CONTINUOUS FLOW METHODOLOGIES
Abstract: Membrane-based separation technologies have emerged as indispensable tools in water purification, biomedical engineering, pharmaceutical processing, and environmental protection. However, conventional membrane fabrication processes often rely on hazardous organic solvents, energy– intensive steps, and environmentally taxing conditions. In response to increasing global emphasis on sustainability and regulatory pressures, green chemistry strategies have gained attention for enabling safer, energy-efficient, and eco-friendly membrane production. This review provides a comprehensive and structured analysis of …
Published in International Journal of Membranes · Vol. 3, Issue 1, 2026 · pp. 8–24 Read article
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Epigenetic Modifications in Health, Disease, and Precision Therapeutics (From Genome to Epigenome)
Abstract: Introduction: Epigenetic alterations play a crucial role in regulating gene expression in both normal physiological and disease states. These reversible modifications—such as DNA methylation, histone acetylation, phosphorylation, ubiquitination, and chromatin remodelling—are increasingly implicated in complex diseases including cancer and neurodegenerative disorders. Despite advances in standard therapeutic approaches, patient responses remain variable, largely due to genetic heterogeneity and epigenetic dysregulation. This highlights the need for incorporating epigenetic understanding into personalized medicine. …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 Read article
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A SEIR-Informed Stacked Fusion of Prophet, XGBoost, and LSTM for Ward-Level Epidemic Forecasting in Amravati Municipal Corporation
Abstract: Municipal epidemic preparedness depends on accurate short-horizon forecasts at fine spatial granularity. Ward-level incidence series are typically nonstationary due to changing contact patterns, interventions, reporting delays, and heterogeneous demographic and environmental factors. This paper presents a mathematically formulated hybrid forecasting architecture designed for Amravati Municipal Corporation (AMC). The method decomposes observed incidence into (i) a mechanistic SEIR baseline that enforces epidemiological structure and (ii) a data-driven residual learned using Prophet …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 13, Issue 1, 2026 · pp. 17–23 Read article
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Harnessing Deep Learning to Explore Microbial Community Structure and Carbon Storage Capacity in Mangrove Ecosystems: A Framework for Computationally
Abstract: Mangrove ecosystems represent one of the most efficient natural carbon sinks on Earth, functioning as critical blue carbon habitats that sustain diverse microbial communities responsible for biogeochemical cycling and long-term carbon storage. Despite their global ecological significance, accurately quantifying and predicting carbon sequestration in mangrove systems remains challenging due to the complex interactions between microbial diversity, sediment chemistry, and environmental drivers. This study presents a comprehensive and sustainable artificial intelligence …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 1, 2026 · pp. 41–49 Read article
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Clinical metabolomics: Useful insights, perspectives, and challenges.
Abstract: Metabolomics provides a comprehensive snapshot of smallmolecule intermediates and end products of cellular processes and thereby links genotype, environment, and phenotype in human disease . Over the last decade, advances in liquid chromatography–mass spectrometry (LC–MS) and nuclear magnetic resonance (NMR) spectroscopy have enabled high-throughput profiling of thousands of metabolites from microliter volumes of clinical samples . Clinical metabolomics is now emerging as a tool for disease diagnosis, risk prediction, therapeutic …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 29–37 Read article
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Comparative Analysis of Processing-Property Relationships in Metal and Polymer Matrix Composites: A Unified Statistical Framework for Hardness Characterization
Abstract: Composite materials, encompassing both metal matrix composites (MMCs) and polymer matrix composites (PMCs), exhibit complex processing-property relationships that fundamentally govern their mechanical performance across diverse applications. This study presents a unified statistical framework for analyzing hardness characteristics in composite systems, using aluminum-tungsten carbide (Al-WC) metal matrix composites as a representative model system while establishing connections to polymer matrix composite behavior. The investigation employed comprehensive processing parameter optimization, microstructural characterization, and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 419–430 Read article
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Plant-Derived Antimicrobials as Next-Generation Solutions to Multidrug Resistance
Abstract: The steady rise of multidrug-resistant (MDR) pathogens is reshaping how clinicians, researchers, and policymakers think about infection control. When bacteria acquire the ability to survive exposure to three or more antibiotic classes at once—whether through efflux pumps, enzyme-mediated drug destruction, target modifications, or reduced membrane permeability—treatment options narrow dramatically, hospital stays lengthen, and mortality climbs. Conventional pharmaceutical pipelines have struggled to keep pace with this biological arms race, pushing the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 · pp. 27–40 Read article
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Effect of Local Application of Phenytoin on Wound Healing in Surgical Wounds: A Scientific Review
Abstract: Surgical wound healing is a dynamic biological process influenced by local tissue response, vascularity, infection control, and systemic patient factors. Delayed wound healing contributes significantly to postoperative morbidity and healthcare costs. Phenytoin, a hydantoin derivative traditionally used as an antiepileptic agent, has demonstrated unexpected wound-healing properties when applied topically. This review critically evaluates experimental and clinical evidence regarding the role of locally applied phenytoin in enhancing wound healing in surgical …
Published in Research and Reviews : Journal of Surgery · Vol. 15, Issue 1, 2026 · pp. 15–19 Read article