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60 articles for “E. coli”
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Extended-spectrum beta-lactamases (ESBLs) and Metallo-beta-lactamases (MBLs): A Review
Abstract: Gram-negative bacteria produce extended-spectrum beta-lactamases (ESBLs) and metallo-beta-lactamases (MBLs), enzymes that play a crucial role in antibiotic resistance. These enzymes enable the bacteria to withstand a wide array of beta-lactam antibiotics, including penicillins, cephalosporins, and carbapenems. The production of these enzymes, particularly by organisms, such as Escherichia coli and Klebsiella pneumoniae, complicates treatment options for severe infections, leading to increased morbidity and mortality in clinical settings. ESBLs are primarily responsible …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 2, 2025 · pp. 8–19 Read article
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Unveiling the Silent Threat: The Escalation and Defence Against Antibiotic Resistance
Abstract: The global challenge of antibiotic resistance presents a significant risk to public health, driven by multifaceted factors worldwide. This issue, akin to the impacts of climate change, requires concerted efforts at national and international levels to mitigate its consequences. Antibiotics have revolutionized modern medicine, enabling critical interventions like surgeries, transplants, and cancer treatments. However, without global collaboration, we face significant setbacks across medical, social, and economic domains. Initiatives to address …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–26 Read article
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Formulation and Evaluation of Polyherbal Soap with Antibacterial and Dermatological Benefits: A Polymer Chemistry Approach
Abstract: This study investigates the formulation and evaluation of polyherbal soap composed of extracts from Vitex negundo, Azadirachta indica, and Curcuma longa. These plants possess significant antibacterial, dermatological, and skin-nourishing properties. The soap formulation follows a saponification process using coconut oil and sodium hydroxide as primary reactants, incorporating polymer chemistry principles in soap structuring and stability. Polymers such as polysaccharides and fatty acid chains contribute to the stability, viscosity, and foaming …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 158–164 Read article
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Assessment of Physico-Chemical and Microbial Analyses of Hand Dug Wells in Makeni Town, Sierra Leone
Abstract: The various water samples were analysed for residual chlorine, ammonia, fluoride, nitrate, sulphite, lead, arsenic, chromium, and bicarbonate levels from January to August 2024. The bacteria contamination was investigated to determine the safety of the water for the consumption of human. The temperatures across the four wells ranged 27.3oC to 30.0oC, with and average values ranging from 27.94oC to 29.15oC. pH values were within the WHO recommended guidelines range of …
Published in International Journal of Pollution: Prevention & Control · Vol. 2, Issue 2, 2024 · pp. 01–13 Read article
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Design of Dual Media Water Filter Purifier Using Clay Pot
Abstract: Numerous organisations make low-cost water treatment devices for rural homes, for instance filters, RO and UV-based water purifiers. However, these devices have problems like filter clogging, the need to replace filters frequently water contamination (in the case of RO), and the truth that electricity is not always available in rural areas, which makes them costly to use. Because of this, RO and UV purifiers are too expensive for people who …
Published in Journal of Water Pollution & Purification Research · Vol. 12, Issue 3, 2025 · pp. 94–99 Read article
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Characterization of Synthesized Heterocyclic Oxadiazole Derivatives Using Mass, UV, IR, and NMR Spectroscopy, Among other Spectroscopic Techniques: Review
Abstract: The current study synthesized and assessed 3-heteroarylazo 4-hydroxy coumarin derivatives' initial antibacterial activities in vitro against four distinct pathogenic bacterial strains, including Pseudomonas aeruginosa, Bacillus subtilis, Escherichia coli, and Staphylococcus aureus. Ampicillin, a common medication, was used to compare each compound's antibacterial properties. UV, IR, 1H NMR, mass spectroscopy, and X-ray diffraction examinations were used to analyze the compounds. By using UV–vis spectra, the solute-chromic behavior of these compounds was …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 1, Issue 1, 2023 · pp. 28–33 Read article
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Mechanism of Action of Essential Oils and their Major Components
Abstract: The essential oil of lemongrass, palm rosa and eucalyptus were found to be good antimicrobial agents. To a large extent the results suggest their potential use as chemotherapeutic agents, food preserving agents, and disinfectants. However before considering these compounds as chemotherapeutic agents against human/animal diseases, it is important to study their cytotoxic and mutagenic effects. Studies were then carried to investigate the probable mechanism by which these compounds act against …
Published in Research & Reviews : Journal of Botany Read article
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Synthesis and antibacterial studies of some bivalent transition metal ions Zn (II), Cu (II) and Ni (II) complexes of Schiff’s base derived from some substituted aromatic aldehydes.
Abstract: In this study, Schiff bases were synthesised through the condensation of aromatic aldehydes with primary amines and subsequently complexed with Ni(II),Zn(II) and Cu(II) ions. The formation of the metal complexes was confirmed by FTIR spectroscopy, which identified the key functional groups involved in coordination. The biological activity of the prepared compounds were studied with the help of selected bacteria like E. coli , Pseudomonas. and B. sereus.. The results obtained …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 2, 2025 · pp. 96–104 Read article
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Synthesis, Characterization of New Imidazolidin-4-One Containing Azo Compound Derived from Acetylacetone as Antibacterial and Antioxidant Agents
Abstract: In the present study, new derivatives of imidazolidine-4-one was prepared. Which involved reactions to diazonium salt of o-methoxy aniline with acetylacetone in the presence of sodium hydroxide, and isolating the azo compound as a brown precipitate. The azo diketone reacts efficiently with aromatic amine derivatives to produce Schiff bases as a light yellow and dark brown precipitates, and from this Schiff bases three derivatives of imidazolidine-4-one was prepared by reacting …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 17, Issue 1, 2026 · pp. 94–114 Read article
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Identifying Origin of Replication (ORI) sites in genomic sequence using Python-based programming and Motif analysis in Bioinformatics
Abstract: ORI sites serve a critical function in DNA replication serving as the beginning point of the process. Identifying the spots appropriately means a lot and is important for the biologists working in the lab. Detecting the ORI is not only vital for the detection of replication sites but is also important in numerous biological processes. In this study, we offer a unique approach employing Python-based motif analysis to discover the …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 3, 2024 · pp. 22–33 Read article
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Preparation and Characterization of Clay-Based Hybrid Membranes for Antibacterial Biodegradable Polymer Wound Dressings
Abstract: Recent developments in the field of polymer chemistry have resulted into many new forms of Hybrid polymer. This has further revolutionized the application of polymer chemistry in numerous fields. In this research, we manufactured clay-based hybrid membrane by adding clay to the biodegradable matrix of chitosan polymer. It is widely known that microbial and pathogenic organisms are being responsible for wound hampering infections such as impetigo. They can spread in …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Exploring the Therapeutic Potential of Phytochemicals in Aloe Barbadensis Miller Through Molecular Docking for Ulcerative Colitis Management
Abstract: Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by mucosal inflammation of the colon, often associated with immune dysregulation and oxidative stress. Natural compounds have gained significant attention as alternative therapeutic agents due to their efficacy and minimal side effects. Quercetin, a flavonoid abundantly found in Allium cepa (onion), has demonstrated potent anti-inflammatory and antioxidant properties. This study employs an in silico approach to evaluate the therapeutic potential …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 1, 2026 · pp. 06–12 Read article
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Review: Virulence factors, resistance genes and pathogenicity of Moraxella catarrhalis
Abstract: An estimated 2-4 million cases of chronic obstructive pulmonary disease(COPD) in adults are exacerbated by Moraxella catarrhalis annually in the US, making it a pathogen of increasing significance for respiratory tract infections. It often colonizes the nasopharynx without causing any symptoms and an opportunistic bacterial infection of the respiratory mucosa that is exclusive to humans. In our study, we reviewed references about the important virulence factors that M. catarrhalis possess …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 33–40 Read article
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Orally Dispersible Tablet of Mesalazine: Formulation and Evaluation
Abstract: Oral disintegrating tablets (ODTs) become increasingly more and more popular, particularly among elderly and paediatric patients who have difficulties with swallowing. The 5-aminosalicylic acid compound oral mesalazine, frequently referred to as mesalamine, is used to treat mild to severe ulcerative colitis and has a high percentage of success in causing and establishing response. Mesalazine has a topical therapeutic action at the location of the suffering colonic mucosa. The medication’s disadvantage …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 · pp. 16–25 Read article
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Determination and Study of The Effect of High Concentrations from Heavy Metals in Environmental Samples
Abstract: This study focused on determining the concentrations of heavy metal ions to assess the environmental pollution levels of five T stations. Based on this, five samples were collected from different environments in Najaf Governorate, and the levels of heavy metal pollution were compared with the permissible values set by the World Health Organization. The research study concerned measurements of the increase and decrease in the concentration of elements and minerals …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 2, 2025 · pp. 77–84 Read article
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Assessment of Groundwater Quality in Rumuodara, Rivers State, Nigeria
Abstract: The assessment of groundwater quality from selected borehole in Rumuodara, Rivers State, Nigeria was evaluated. The results of the physicochemical parameters revealed that pH ranged from 6.57-6.60, temperature: 26.10-28.54oC, turbidity: 1.57-2.96NTU, conductivity: 41.24-68.44 μS/cm, salinity: 26.10-50.37mg/l, total dissolved solid: 18.9-63.14mg/l, total hardness: 38.21-48.30mg/l, alkalinity: 55.30-70.17mg/l, chloride: 28.40-75.14mg/l, sulphate: 21.50-30.60mg/l, nitrate: 1.50-3.04mg/l, phosphate: 59.24-65.40mg/l, calcium: 37.81-45.27mg/l, Iron: 0.133-0.190mg/l, sodium: 16.70- 21.13mg/l, copper: 0.22–0.50mg/l, total suspended solid: 2.94-3.60mg/l, Lead: < 0.01mg/l-2.27mg/l, zinc: …
Published in Research & Reviews : Journal of Ecology Read article
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Assessment of Water Quality along River Ethiope, Delta State
Abstract: The environment, economic growth, and human health all depend on the quantity and quality of water supplies. Given this, the significance of water quality monitoring cannot be overstated.This study was aimed at assessing the water quality of River Ethiope. To achieve this, surface water samples were collected from Ethiope River along its banks at the following towns; Umuaja (SWI), Ebedie (SW2), Abraka (SW3), Sapele (SW4) and Ughara (SW5) axis during …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 2, 2025 · pp. 8–16 Read article
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Comprehensive Overview of Carbohydrate Polymers
Abstract: Targeting drug delivery specifically to the colon has become increasingly crucial for treating various colonic diseases like colorectal cancer, amebiasis, ulcerative colitis, and Crohn’s disease. Numerous strategies have been developed for this purpose, including using enzymatically degradable polymers, employing prodrug-based approaches, coating drugs with polymers sensitive to time or pH changes, utilizing osmotically and pressure-controlled delivery systems. Polysaccharides activated by the colon's physiological environment show significant potential as they offer …
Published in International Journal of Membranes · Vol. 1, Issue 1, 2024 · pp. 8–21 Read article
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Evaluation of Raw Cow Milk Preservation Using Extracted Mango Seed Kernels and Rosemary Leaves Powder, Ethiopia
Abstract: The study aimed to evaluate the raw cow milk preservation using extracted mango seed kernels and rosemary leaves powder. Fresh cow milk samples collected aseptically from Debre Birhan University farm. The fresh cow milk treated at different concentrations (0.5, 1.0 and 1.5%) of ethanol extract of mango seed kernel, rosemary leaves and equal mix of both extracts with 100 ml of milk then store at room temperature. Mango seed kernels …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 14, Issue 2, 2025 · pp. 20–28 Read article
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Ulcerative Colitis- An Ayurvedic Review And Treatment – A Case Study
Abstract: Ulcerative colitis (UC) is a chronic autoimmune disease that causes inflammation and ulcers of the Large intestine. It is one of the most common GI disorder. Usually the pain affects only the intestinal mucosa and sub mucosa, causing small ulcers in the intestinal lining called ulcers. In most of patients, the disease begins from the anus and continues to spread. Its pathogenesis is multi factorial and includes genetic predisposition, epithelial …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2024 · pp. 31–39 Read article