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135 articles for “Diagnostic tests”
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Malaria Diagnosis through Conventional Methods: A Comprehensive Review
Abstract: The incidence of drug-resistant parasite strains is rising, there is an apparent increase in the number of cases of malaria worldwide, and in a small number of cases and there has been a dramatic rise in international migration and travel. Over 1 million people die from malaria every year; 90% of these deaths are in African children, who live in tropical and subtropical regions. Although there are now efficient techniques …
Published in International Journal of Pathogens · Vol. 1, Issue 2, 2024 · pp. 8–14 Read article
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Early Alzheimer's Disease Detection Using Deep Ensemble Learning and MRI Image Analysis
Abstract: Early detection of Alzheimer's disease (AD) is crucial to slowing cognitive decline and enabling timely clinical interventions. Traditional diagnostic methods, including cognitive tests and single-model classifiers, have limited sensitivity during early stages of the disease. This paper presents a deep ensemble learning approach that integrates multiple convolutional neural networks (CNNs) for accurate Alzheimer's disease detection using structural Magnetic Resonance Imaging (MRI) data. The proposed framework utilizes ResNet50, VGG16, and DenseNet121 …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 1, 2026 · pp. 1–9 Read article
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Pathogenesis and Treatment of Tuberculosis (T.B) Disease
Abstract: Tuberculosis (TB) is an infectious illness spread through the air that is caused by organisms from the Mycobacterium tuberculosis complex. M. tuberculosis is a lung infection in primary stage, but it can infect any area of the body. M. tuberculosis infection can progress from latent TB infection, in which the bacteria are isolated within granulomas, to infectious infection, in which the patient develops symptoms such as cough, fever, night sweats, …
Published in Research and Reviews : A Journal of Immunology · Vol. 11, Issue 3, 2021 · pp. 42–48 Read article
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Clinical Medicine Done with Clinical Accuracy
Abstract: The advancement of clinical medicine has progressively underscored the significance of accuracy in diagnosis and therapy. This article examines the concept of "Clinical Medicine Administered with Clinical Precision," emphasising how innovations in diagnostics, data analytics, and personalised treatments are transforming the healthcare environment. Clinicians can provide therapy that is not only successful but also personalised to each patient's requirements by combining evidence-based practices with patient-specific factors including genetic profiles, comorbidities, …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 6–19 Read article
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HPV Screening as an Alternative to Pap Smear in Cervical Cancer Prevention: A Comparative Study in North India
Abstract: Cervical cancer remains a leading cause of cancer-related morbidity and mortality among Indian women, especially in low-resource settings. While Pap smear testing has been the standard screening method, HPV DNA testing offers potential advantages in sensitivity, cost-effectiveness, and feasibility for large-scale implementation. This study compares the efficacy, cost, and acceptability of HPV screening versus Pap smears in urban and rural populations of North India. A comparative cohort study was conducted …
Published in International Journal of Women's Health Nursing And Practices · Vol. 3, Issue 2, 2025 · pp. 31–37 Read article
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Extreme Value Analysis of Rainfall using L-Moments of Five Probability Distributions for Chandwa and Latehar Sites in Jharkhand
Abstract: Estimation of rainfall for a given return period is of utmost importance for planning, design and management of civil and hydraulic structures. This can be achieved by conducting Extreme Value Analysis (EVA) of rainfall that consists of fitting probability distributions (PDs) to the annual maximum series of rainfall. In this paper, a study on intercomparison of L-Moments (LMO) of five PDs viz., Extreme Value Type-1 (EV1), Extreme Value Type-2, Generalized …
Published in Journal of Water Resource Engineering and Management · Vol. 9, Issue 1, 2022 · pp. 42–50 Read article
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Estimation of Peak Flood Discharge for the Ungauged Catchments in the Tributaries of River Sutlej using Synthetic Unit Hydrograph Approach
Abstract: Estimation of peak flood discharge (PFD) for a given return period is of utmost importance for planning and design of hydraulic structures, river protection works, and development of integrated water resources management projects which can be computed by applying various approaches viz., flood frequency analysis, rational formula, envelope curve and synthetic unit hydrograph (SUH). In this paper, SUH approach is adopted for estimation of PFD for the ungauged catchments viz. …
Published in Journal of Water Resource Engineering and Management · Vol. 9, Issue 1, 2022 · pp. 29–41 Read article
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Mammographic CADe And CADx for Identifying Microcalcification Using Support Vector Machine
Abstract: The second most frequent cause of death and disease in women worldwide is breast cancer. Effective detection is a crucial element in the successful treatment of cancer. X-ray mammography is the majorityfrequent method for breast cancer. Screenings because of its convenience, portability, and cost-effectiveness. The CADe and CADx techniques were designed to assist radiologists in improving the detection and screening of breast cancer. The goal is for breast cancer to …
Published in Journal of Communication Engineering & Systems · Vol. 10, Issue 2, 2020 · pp. 9–16 Read article
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Next Generation Immunoassays for Infectious Diseases of Animals
Abstract: Veterinary diagnostics has an essential role to play in the management and control of infectious diseases. Immunodiagnostics originated towards the end of 19th century with the advent of agglutination- and precipitation-based serological techniques. Progress in immunodiagnostics during the 20th century is marked by development of complement fixation test, and later, fluoro-, radio- and enzyme-immunoassays during 1950s, 1960s and 1970s, respectively. Various immunodiagnostic test formats were improved for their performance characteristics …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 2, 2017 · pp. 22–43 Read article
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Wiskott-Aldrich Syndrome: A Comprehensive Guide
Abstract: Wiskott-Aldrich Syndrome (WAS) is an uncommon genetic disorder inherited through the X chromosome, marked by a combination of immune system deficiencies, eczema, and low platelet counts. This syndrome primarily affects males, leading to significant morbidity and mortality due to recurrent infections, bleeding complications, and autoimmune diseases. Mutations in the WAS gene disrupt the production of the Wiskott-Aldrich Syndrome protein (WASp), crucial for the functioning of immune cells and platelet formation. …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 39–46 Read article
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Cartridge-Based Nucleic Acid Amplification for Rapid Tuberculosis Diagnosis
Abstract: In terms of public health, tuberculosis continues to have a significant impact on people's lives. The process of determining the underlying cause of a sickness or condition in a patient is known as clinical diagnosis. It entails the use of numerous diagnostic methods, including physical examinations, laboratory testing, and imaging procedures for medical purposes. Smear microscopy, which are frequently utilized, have poor sensitivity and lengthy turnaround times, respectively. An innovative, …
Published in International Journal of Pathogens · Vol. 1, Issue 1, 2024 · pp. 43–48 Read article
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Paediatric Epilepsy: Current Advances in Diagnosis and Management
Abstract: Paediatric epilepsy is one of the most common chronic neurological disorders of childhood, characterised by recurrent unprovoked seizures resulting from abnormal neuronal activity. Accurate diagnosis is essential and is based on a detailed clinical history, seizure semiology, neurological examination, and electroencephalography (EEG), with neuroimaging such as magnetic resonance imaging (MRI) used to identify structural abnormalities. Classification according to seizure type and underlying aetiology genetic, structural, metabolic, immune, infectious, or unknown—guides …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 53–68 Read article
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Canine Ehrlichiosis and Its Diagnostic Techniques: Review
Abstract: Canine monocytic ehrlichiosis, caused by Ehrlichia canis is one of the important immuno-suppressive infectious vector-borne diseases of dogs. Importantly, canine ehrlichiosis can be caused by different Ehrlichia species, which are intracellular rickettsial organisms belonging to the order Rickettsiales and included in the family Rickettsiaceae. Ehrlichias are the obligate intracellular organisms that affects the host immunologic response. It is typically a disease of leukocyte and platelet manifested by an acute reduction …
Published in Research and Reviews : A Journal of Immunology · Vol. 10, Issue 1, 2020 · pp. 1–11 Read article
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Systematic Review on: Peptic Ulcer and Its Management
Abstract: Peptic ulcer disease (PUD), which affects 5–10% of people worldwide, is still a significant global health concern. Gastric acid and pepsin's corrosive effects cause mucosal injury in the stomach, duodenum, or lower oesophagus. Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori infection are the primary reasons. This review's goal is to examine PUD's aetiology, risk factors, pathophysiology, clinical symptoms, diagnostic methods, and evidence-based treatment modalities. PubMed, Google Scholar, …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 1, 2026 Read article
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Systematic Review on: Peptic Ulcer and Its Management
Abstract: Peptic ulcer disease (PUD), which affects 5–10% of people worldwide, is still a significant global health concern. Gastric acid and pepsin's corrosive effects cause mucosal injury in the stomach, duodenum, or lower oesophagus. Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori infection are the primary reasons. This review's goal is to examine PUD's aetiology, risk factors, pathophysiology, clinical symptoms, diagnostic methods, and evidence-based treatment modalities. PubMed, Google Scholar, …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 1, 2026 · pp. 60–64 Read article
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FMR1 Key Biomarker in Fragile X Syndrome- A Comprehensive Review
Abstract: Fragile X Syndrome (FXS) is a complicated neurodevelopmental condition that causes intellectual disabilities, behavioural issues, and a variety of physical symptoms. Central to understanding FXS is the Fragile X Mental Retardation 1 (FMR1) gene, pivotal in the disorder's pathogenesis. This review examines FMR1 as a key biomarker in FXS, drawing on recent research insights. The FMR1 gene, situated on the X chromosome, encodes the fragile X mental retardation protein (FMRP), …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 8–18 Read article
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Clinical Study for Evaluation of Comprehensive Ayurvedic Management in Nicotine Use Disorder
Abstract: Substance use disorder (SUD), is a condition in which the use of one or more substances leads to a clinically significant impairment or distress. 'Substance' in this clinical study is limited to nicotine-based substances (Nicotine Use Disorder). This study evaluates the effect of Ayurvedic management on Nicotine Use Disorder. 36 Patients were registered in this study having signs and symptoms of nicotine use disorder and were treated with Ayurvedic management …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 7, Issue 2, 2020 · pp. 14–22 Read article
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Principles of Computer Infrared Spectroscopic Diagnostics, Classification and Prognostication of the Methods of Treatment of the Tumors
Abstract: The paper presents the formulated principles of computer infrared spectroscopic diagnostics, classification and prognostication of the methods of treatment of the tumors that permit to develop original software. The developed software allows using of the modern methods of physical chemistry analysis and mathematical modeling in diagnostics, treatment and management of the oncological patients. The essence of this using consists of in the establishment of the basic physical chemistry reasons for …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 8, Issue 1, 2019 · pp. 1–4 Read article
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Complex Tuberculous Meningitis: A Case Series Highlighting Rare Co-infections and Severe Complications
Abstract: This case series presents two complex cases of tuberculous meningitis (TBM) with different complications, illustrating the diverse clinical presentations and management challenges of this disease. Case 1 involves an 18-year-old female with TBM complicated by cryptococcal co-infection, while Case 2 describes a 64-year-old female with TBM complicated by obstructive hydrocephalus and secondary bacterial infections. Both patients had been on anti-tubercular therapy before presentation. Diagnostic approaches included cerebrospinal fluid analysis, cultures, …
Published in International Journal of Pathogens · Vol. 1, Issue 2, 2024 · pp. 1–7 Read article
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Skin Prick Test and Intradermal Test in Allergic Disorders: Clinical Relevance
Abstract: Allergic diseases are one of the commonest ailments affecting individuals of all age groups globally and their prevalence has been increasing exponentially. Allergy skin testing was started in 1860 by Blackley as a diagnostic tool. Since then, it has been the standard clinical method to demonstrate the presence of allergen-specific IgE antibodies in allergic diseases. There is now consistent evidence that if we decrease sensitization to an allergen, we can …
Published in Research and Reviews : A Journal of Immunology · Vol. 12, Issue 1, 2022 · pp. 23–34 Read article