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177 articles for “Clinical Precision”
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Enhanced Diabetes Prediction: A Comparative Study of Machine Learning Models
Abstract: Excessively high blood glucose levels lead to diabetes, a condition that can be better managed with early detection, resulting in a longer life and improved health. Machine learning models are essential tools in diagnosing diabetes, especially when trained on appropriate and relevant datasets. In this study, a combination of ensemble methods and nine distinct machine learning algorithms were utilized to develop a predictive model for diabetes diagnosis based on a …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 2, 2025 · pp. 1–10 Read article
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A Review on Lung Cancer Prediction Using Machine Learning
Abstract: Lung cancer continues to be a major contributor to cancer-related mortality across the globe. Timely diagnosis and reliable prediction models play a crucial role in enhancing treatment outcomes and survival rates for patients. The present study focuses on the utilization of machine learning (ML) methods for the prediction of lung cancer. Using datasets that incorporate clinical records, imaging modalities, and genetic profiles, the research assesses the predictive capabilities of multiple …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 3, 2025 · pp. 1–11 Read article
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Crispr Cas – Revolutionizing Modern Therapies and Beyond
Abstract: CRISPR-Cas technology has emerged as a transformative tool in modern molecular biology, revolutionizing both fundamental research and clinical applications. This RNA-guided gene-editing system enables precise and efficient genomic modifications, offering unprecedented potential for addressing genetic disorders, infectious diseases, and oncological conditions through innovative therapeutic interventions. The inherent specificity and programmability of CRISPR-Cas systems have facilitated breakthroughs in diverse fields, including precision medicine, regenerative therapies, and immuno-oncology. Beyond its therapeutic applications, …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 25–38 Read article
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A Systematic Review on Leukemia Detection and Classification Techniques Using Gene Expression
Abstract: Early diagnosis of genetic diseases is crucial for effective treatment, especially in the case of Leukemia, a type of blood cancer characterized by abnormal proliferation of white blood cells. This paper presents a systematic review of recent computational techniques for the detection and classification of Leukemia using gene expression data obtained from DNA microarray analysis. The study explores diverse methodologies including machine learning (ML), deep learning (DL), and bio-inspired algorithms …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 Read article
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The Role of Bioinformatics in Nursing: Transforming Healthcare through Data-Driven Insights
Abstract: Bioinformatics, an interdisciplinary field combining biology, computer science, and information technology, is increasingly shaping the nursing profession. It offers powerful tools for improving patient care, advancing clinical research, and enabling personalized healthcare through data-driven decision-making. This article examines the integration of bioinformatics into nursing practice, tracing its historical roots from the Human Genome Project to its current applications in genomic medicine, precision healthcare, and population health. Nurses now play a …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 3, 2024 · pp. 18–21 Read article
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Refining Retinal Layer Segmentation in OCT Imaging with Advanced Techniques and Clinical Applications
Abstract: Segmenting retinal layers from Optical Coherence Tomography (OCT) pictures entails locating and separating different retinal layers to offer comprehensive anatomical and pathological information. Age-related macular degeneration, diabetic retinopathy, and glaucoma are among the retinal illnesses for which this procedure is crucial for diagnosis and follow-up. By utilizing preprocessing techniques to improve image quality and applying advanced algorithms—such as intensity-based, gradient-based, and texture-based methods—alongside deep learning approaches, clinicians can accurately measure …
Published in Trends in Opto-electro & Optical Communication · Vol. 14, Issue 2, 2024 · pp. 01–06 Read article
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Comprehensive Review of Adenoid Cystic Carcinoma: Pathogenesis, Diagnosis, and Emerging Therapeutic Approaches
Abstract: Adenoid cystic carcinoma (ACC)is an infrequent neoplasm, highly malignant, that develops mainly in the salivary glands with the potential to exist in any secretory glandular sites, including the lacrimal glands, breast, and respiratory tract. ACC usually has a benign initial course, but conversely, it is notoriously aggressive in behavior with high incidence of perineural invasion, local recurrence, and distant metastasis, mostly to the lungs. The tumor’s molecular features are characterized …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 3, 2025 · pp. 1–17 Read article
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Epigenetic Modifications in Health, Disease, and Precision Therapeutics (From Genome to Epigenome)
Abstract: Introduction: Epigenetic alterations play a crucial role in regulating gene expression in both normal physiological and disease states. These reversible modifications—such as DNA methylation, histone acetylation, phosphorylation, ubiquitination, and chromatin remodelling—are increasingly implicated in complex diseases including cancer and neurodegenerative disorders. Despite advances in standard therapeutic approaches, patient responses remain variable, largely due to genetic heterogeneity and epigenetic dysregulation. This highlights the need for incorporating epigenetic understanding into personalized medicine. …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 Read article
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Gene Therapy in Modern Medicine: Promises and Challenge in Treating Genetic Diseases
Abstract: Gene therapy is a medical approach that focuses on altering or adjusting an individual’s genes to treat or prevent illnesses. The aim is to repair faulty genes or insert new ones into the body to combat diseases. Gene therapy can involve directly introducing modified or new genes into a patient’s cells or altering the genes already present in the patient’s body. This approach shows potential for treating a range of …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 27–32 Read article
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Early Autism Diagnosis: Machine Learning Models and Their Effectiveness
Abstract: Diagnosis is of utmost importance for timely intervention and support. However, traditional diagnosis methods, which are based on subjective assessment, are delayed. This project explores the role that machine learning techniques might play in enhancing the accuracy and effectiveness of ASD detection. Several state-of-the-art classification algorithms were benchmarked using a dataset from Kaggle. Logistic Regression, XG Boost, Random Forest, Decision Tree, and Gradient Boosting were taken into consideration. Other performance …
Published in Journal of Instrumentation Technology & Innovations · Vol. 14, Issue 2, 2024 Read article
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Herbal Medicines and Complementary Therapies: Their Role, Types and Applications
Abstract: Medicinal plants are used in herbal medicine to treat and prevent illnesses. This includes the use of standardized and titrated botanical extracts in addition to common and traditional medicines from different cultures. The safety of a treatment may be suggested by its long history and deep cultural roots in traditional medical systems, but this does not always imply that it is effective. This is especially important in herbal medicine, since …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 40–53 Read article
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Breast Cancer Detection Using Machine Learning: A Comparative Analysis of Supervised Learning Algorithms
Abstract: Globally, breast cancer remains a predominant cause of mortality among women, highlighting the urgent need for timely and precise diagnostic approaches. This research explores the application of machine learning algorithms—including Logistic Regression, SVM, Naïve Bayes, KNN, and Random Forest—on the Wisconsin Breast Cancer Dataset for effective tumor classification. Key pre-processing steps such as missing value handling, feature scaling, and dimensionality reduction were employed to improve model performance. The study evaluated …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 3, 2025 · pp. 46–52 Read article
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A review on scope and use of Robots in healthcare sector in Kerala and related ethical issues
Abstract: In today’s rapidly evolving world, robots have become integral to various industries, including healthcare. Their precision, efficiency, and ability to perform repetitive tasks have transformed patient care and clinical procedures. While developed countries have embraced robotic technologies, India, particularly Kerala, is still in the early stages of integrating robots into healthcare. Surgical assistance and patient rehabilitation are key use cases. However, this adoption raises ethical, privacy, and regulatory concerns. As …
Published in Journal of Production Research & Management Read article
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Brain Tumor Detection Using RestNet50 Architecture
Abstract: This paper presents a novel deep learning model for brain tumor diagnosis from MRI scans on the basis of ResNet50 with some modifications. Optimizing the modified layers and pre-trained ResNet50 for improved diagnostic accuracy and reliability in real-world clinical settings is one of the key contributions of this paper. The model was trained on an extremely well-balanced data of 2,577 MRI scans, which were split equally among the tumor and …
Published in Current Trends in Signal Processing · Vol. 15, Issue 2, 2025 · pp. 1–13 Read article
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Next Generation Sequencing (NGS) in Personalized Medicine: Emphasizing Public Health Beyond Reality
Abstract: NGS is a modern technology that allows researchers to quickly sequence large amounts of DNA or RNA, it is also known as massively parallel sequencing or deep sequencing. NGS has revolutionized genomic research and biological sciences by its speed, scale, accuracy, ultra-high throughput, and cost. NGS replaced the conventional sequencing method. A novel idea in healthcare is precision medicine, which involves adjusting medical care to each patient’s unique traits and …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 1–17 Read article
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Monoclonal antibodies in targeted cancer therapy advances, resistance mechanisms, and next-gen formats (Bispesifics, ADCs)
Abstract: Breast cancer is one of the leading causes of cancer-related morbidity and death worldwide, which emphasizes the need for more effective and focused treatment strategies. antibody-mediated drug delivery techniques. Specifically, antibody–drug conjugates (ADCs) have emerged as a potential approach that combines the specificity of monoclonal antibodies with the potent cytotoxicity of anticancer drugs. By selectively targeting tumor-associated antigens, ADCs enhance drug accumulation within cancer cells while minimizing systemic toxicity associated …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 Read article
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Cervical Leiomyomas: Age associated insights from 3 Year prospective study from Tertiary Care Hospital
Abstract: Cervical leiomyomas are rare benign smooth muscle tumours of cervix, often presenting diagnostic challenges due to their uncommon occurrence and overlapping features with other cervical pathologies. This is a 3-year prospective study involving a total of 460 female subjects who were diagnosed with various gynecologic complications, with a particular focus on cervical leiomyomas. The study aims to provide a comprehensive age-wise distribution of cervical leiomyomas, emphasizing the incidence and prevalence …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 Read article
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Advancing Asthma Management: The Synergy of Systems Biology, Artificial Intelligence, and Next-Generation Therapeutics
Abstract: Asthma is an inflammatory disorder of the respiratory tract that is chronic and heterogeneous in nature and has various effects on millions of people. Being a chronic inflammatory disease, asthma remains incurable and the major conventional treatments offer limited success due to the mask nature of its pathophysiology. Systems biology/(AI), and next-generation has greatly enhanced knowledge and the management of asthma. The approaches based on gene, transcript, protein, and metabolite …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 · pp. 1–12 Read article
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Understanding Leukemogenesis: Challenges and Advancements in Diagnostic Approaches
Abstract: Leukaemia development, or leukemogenesis, is a multifactorial process driven by a complex interplay of environmental, genetic, and epigenetic factors. Despite substantial advancements in technology and medicine, which have enhanced our understanding of the contributing factors, early and accurate diagnosis remains a major challenge due to the overlapping clinical features shared by the various leukaemia subtypes. This study explores the molecular and cellular mechanisms underlying leukemogenesis, while also addressing the difficulties …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 1, 2025 · pp. 11–22 Read article
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Overview of Recent Advancement of Nano Stent in Pharmaceutical Application
Abstract: Interventional cardiology has witnessed remarkable progress with the evolution of nanotechnology, leading to the development of nanostents. Nanostents, characterized by their nanoscale features and innovative materials, have emerged as a cutting-edge solution for addressing the limitations associated with traditional stent technologies. This thorough analysis examines the most recent developments in the design, manufacture, and use of nanostents, emphasizing how they may completely transform vascular interventions. The first section of the …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 22–43 Read article