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92 articles for “Chronic inflammation”
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Ulcerative Colitis- An Ayurvedic Review And Treatment – A Case Study
Abstract: Ulcerative colitis (UC) is a chronic autoimmune disease that causes inflammation and ulcers of the Large intestine. It is one of the most common GI disorder. Usually the pain affects only the intestinal mucosa and sub mucosa, causing small ulcers in the intestinal lining called ulcers. In most of patients, the disease begins from the anus and continues to spread. Its pathogenesis is multi factorial and includes genetic predisposition, epithelial …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2024 · pp. 31–39 Read article
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Management of Steroid Induced Diabetes with Unani Medicine: A Case Report
Abstract: Background: Glucocorticoids (GC), such as prednisolone, are commonly used for their anti-inflammatory and immunosuppressive properties. However, chronic GC use can lead to adverse effects, including diabetes. This case study evaluates the efficacy of Arq Afsanteen, an Unani compound drug, in managing GC-induced diabetes. A 50-year-old man with a family history of type 2 diabetes and a history of partial gastrectomy was diagnosed with sarcoid tuberculosis and began treatment with ATT …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 3, 2024 · pp. 49–53 Read article
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An Insilico Study of Isobutrin and Phosphorylase Kinase - A Ray of Hope for Psoriasis Patients – Clinical Hypothesis
Abstract: Psoriasis is a chronic, hyper-proliferative and inflammatory skin disease. Increased levels of the calmodulin-containing enzyme, namely, phosphorylase kinase (PhK), were observed in the human epidermis of the active psoriasis cases. Thus PhK is a potential biomarker for the diagnosis and progression of the skin disease, namely, psoriasis. The search for the potential molecules that could supress the over expression of PhK is underway and any break-through in this direction leads …
Published in International Journal of Cheminformatics · Vol. 2, Issue 1, 2024 · pp. 1–8 Read article
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Barg-e-Tulsi (Ocimum sanctum Linn.) in Unani Medicine: Bridging Classical Therapeutics with Contemporary Pharmacological Evidence
Abstract: In the Unani System of Medicine (USM), Barg-e-Tulsi (Ocimum sanctum Linn.), commonly known as Tulsi or Holy Basil, is a highly valued medicinal herb that has been extensively used for centuries in the prevention and treatment of various ailments. It occupies an important place in traditional Unani therapeutics due to its broad spectrum of medicinal properties and its effectiveness in managing respiratory, gastrointestinal, neurological, and infectious disorders. Classical Unani scholars …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2026 Read article
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Exploring the Therapeutic Potential of Phytohormones: Bridging Plant Immunity and Human Health
Abstract: This review highlights the multifaceted roles of phytohormones, including salicylic acid, abscisic acid, cytokinins, and brassinosteroids, emphasizing their contributions to plant immunity and potential therapeutic applications in human health. Phytohormones are critical regulators of plant growth, development, and defense, functioning as signaling molecules that activate and coordinate plant responses to biotic and abiotic stresses. Salicylic acid, in particular, is instrumental in systemic acquired resistance (SAR), a defense mechanism that strengthens …
Published in International Journal of Trends in Horticulture · Vol. 1, Issue 2, 2024 · pp. 20–23 Read article
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Phytochemical and Nutritional Aspects of Wild Edible Plants from Shivalik Hills of Himachal Pradesh: A Review
Abstract: The Shivalik Hills of Himachal Pradesh, a region known for its rich biodiversity, is home to a wide variety of wild edible plants (WEPs) that have long been integral to the diet and health practices of local tribal communities. These plants have been prized for generations not just for their culinary applications but also for their important nutritional and therapeutic qualities. The current study delves into the phytochemical and nutritional …
Published in Research & Reviews : Journal of Ecology · Vol. 13, Issue 3, 2024 · pp. 24–32 Read article
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Rheumatoid Arthritis and Stem Cell Therapies Perspectives for It
Abstract: Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by systemic inflammation, primarily affecting synovial joints, leading to joint destruction and systemic complications. The pathogenesis involves immune system dysregulation, autoantibody production, and enzymatic imbalances. Enzymes, including matrix metalloproteinases (MMPs), serine proteases, and kinases, play crucial roles in these processes. Their dysregulation contributes significantly to disease progression through the imbalance of pro-inflammatory cytokines, oxidative stress, and extracellular matrix (ECM) degradation. MMPs, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article
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Infective Endocarditis, Result of Chronic Periodontal Disease: A Real and Present Danger
Abstract: Introduction: Endocarditis is an inflammation of the endocardium, the inner lining of the heart and heart valves. It is usually caused by bacteria and is associated with high mortality and morbidity. It can result from transient bacteremia from the oral cavity. Streptococci are the primary colonizers of tooth surface and are instrumental in development of the complex oral biofilm, dental plaque. Streptococcus sanguinis is one of the abundant oral commensals …
Published in Research and Reviews: A Journal of Dentistry Read article
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SIBR/Aloe barbadenis Mill.: A Review on Medicinal Utility from the Perspective of Unani Medicine
Abstract: Aloe barbadensis Mill., known as Sibr in Unani medicine, is a time-honored medicinal plant belonging to the family Liliaceae. Revered across cultures and healing systems, it has been extensively described in Unani literature under various names such as Elwa, Musabbar, and Ghikwar. This review aims to comprehensively explore the medicinal utility of Sibr from an Unani perspective while integrating evidence from modern pharmacognosy, phytochemistry, and pharmacology. Traditionally, the dried juice …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 3, 2025 · pp. 22–29 Read article
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Plant Bioactive Metabolites and Their Role in the Prevention and Control of Dental Diseases and Infections.
Abstract: The oral diseases, including dental caries and periodontitis, affect masses worldwide, and have historically been managed with synthetic antimicrobials that cause deleterious side effects, leading to mounting bacterial resistance. Consequently, contemporary dentistry is rapidly shifting toward phytomedicine using plant bioactive molecules, such as polyphenols, terpenes, anthraquinones (berberin, eugenol, curcumin, catechins, allicin, and azadirachtin. These compounds offer potent antimicrobial, anti-inflammatory, and tissue-regenerative properties that are crucial for preventing and curing dental …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 47–66 Read article
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DMARDs, Biologic Agents and Novel Experimental Strategies in The Treatment of Rheumatoid Arthritis
Abstract: An inflammatory and autoimmune disease, rheumatoid arthritis (RA) causes severe pain and inflammation in affected areas of the body. According to the report, there is no known cure for RA. Therefore, reducing discomfort and halting future harm must be the goals of present therapy. For the purpose of prevention and to reduce disease activity in RA patients, significant success has been achieved with the continued development of disease-modifying antirheumatic drugs …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 14–24 Read article
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Ilaj bil-Ma’ (Hydrotherapy) as a Regimenal Modality in Pain Management: Conceptual Foundations in Unani Medicine and Modern Correlation
Abstract: Waja‘ (pain) is one of the most common clinical complaints encountered worldwide and remains a leading cause of disability, impaired functional capacity, and diminished quality of life. In the Unani system of medicine, pain is not considered merely a symptom but a significant manifestation of disturbed physiological balance. Classical Unani scholars describe pain as arising from derangement in Mizāj (temperament), imbalance of Akhlāṭ (humours), Sudad (obstruction within bodily channels), Waram …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2026 · pp. 12–19 Read article
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From Clinic Formulation to Development of Acebrophylline
Abstract: Acebrophylline, a commonly utilized bronchodilator with anti-inflammatory properties, has become a key therapeutic option for managing respiratory conditions like asthma, chronic obstructive pulmonary disease (COPD), and chronic bronchitis. This review explores the journey of Acebrophylline from its clinic formulation to its development and commercialization, focusing on the key aspects of formulation strategies, pharmacological properties, and regulatory considerations. The drug’s dual mechanism of action, which involves both bronchodilation and anti-inflammatory effects, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 35–48 Read article
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Fenugreek: A Traditional Herb with Modern Health Applications
Abstract: Fenugreek (Trigonella foenum-graecum) is a remarkable herb with a rich history that stretches back over 4, 000 years. It has played an important role in traditional medicine systems like Ayurveda, Unani, and Traditional Chinese Medicine. Cultivated widely in places like India, the Mediterranean, and North Africa, fenugreek’s seeds and leaves have been used to treat a variety of ailments, from digestive and respiratory issues to skin problems and inflammation. Recent …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 1, 2024 · pp. 11–21 Read article
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A Computational Study to Elucidate the Phytochemicals as An Antagonist Against Pruritis in Psoriasis
Abstract: Objective: Psoriasis is a chronic, non-contagious, auto-immune skin disorder that causes inflammation, pain, and itching in the affected areas. The etiology of this condition is not entirely understood, and while there are treatments available to manage the symptoms, there is currently no cure. The Transient receptor potential cation channel, subfamily Vanillin, member 3 (TRPV3), present in keratinocytes, allegedly had a part in the development of psoriasis-related pain and itching. Specifically, …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 49–61 Read article
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Clinical experience with Ayurvedic Treatment in Case of Rheumatoid Arthritis – Ayurvedic review and Case study
Abstract: Rheumatoid arthritis is the most found inflammatory auto immune disease with unknown etiology. Many clinical features and treatment strategies of RA are associated with multiple joint diseases. The clinical phenotype of Rhematoid arthritis is a symmetrical, deformed polyarthritis of small and large joints, which is often associated with features of the disease. The treatment typically involves ongoing management with periods of worsening symptoms followed by periods of improvement. Features of …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 2, 2024 · pp. 1–8 Read article
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The Nutritional Value of Moringa Plant as a Superfood: A Comprehensive Review
Abstract: Moringa oleifera, commonly known as the "miracle tree," has garnered global attention for its rich nutritional profile and diverse medicinal properties. This review article comprehensively explores the nutritional composition and health benefits of Moringa, highlighting its potential as a superfood. The plant is rich in essential nutrients, including proteins, vitamins, minerals, and bioactive compounds, such as flavonoids and phenolic acids. These constituents contribute to its antioxidant, anti-inflammatory, antimicrobial, and anti-cancer …
Published in International Journal of Sustainability · Vol. 1, Issue 2, 2024 · pp. 20–23 Read article
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Comprehensive Study and Triggering Factors of Alcoholic and Non-Alcoholic Fatty Liver
Abstract: Over the past few years, fatty liver disease has turned out to be a rather widespread phenomenon and has become a serious issue with the global population nowadays. It comprises alcoholic fatty liver disease and non-alcoholic fatty liver disease, which develop under the influence of various initiating factors, though frequently follow similar pathologies. The overloading of lipids in the hepatocytes in most cases will be the first sign of the …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 43–52 Read article
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SGLT2 Inhibitors in Heart Failure and Chronic Kidney Disease: Expanding Therapeutic Horizons beyond Glycemic Control
Abstract: Heart failure (HF) and chronic kidney disease (CKD) are closely related clinical diseases that significantly increase morbidity and death worldwide. The co-occurrence of both conditions is frequently referred to as the "cardio-renal syndrome," in which the failure of one organ hastens the decline of the other. The original purpose of sodium–glucose cotransporter-2 (SGLT2) inhibitors was to treat type 2 diabetic mellitus (T2DM) by reducing blood sugar levels. Nevertheless, new data …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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Impact of Hypoxia on Cardiopulmonary Adaptation in Canines: A Comprehensive Review
Abstract: Hypoxia triggers a series of cardiopulmonary responses that play an important role in oxygen delivery and the continuation of physiological activity in mammals. Canines are also a useful translational model of study to examine these adaptive responses because of their anatomical, physiological, and cardiopulmonary differences with humans. This review summarizes the experimental data of acute, subacute and chronic hypoxia in dogs with particular focus on the variations in cardiac functioning, …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 15, Issue 1, 2026 · pp. 13–24 Read article