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72 articles for “Adverse drug reaction”
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A Review on Transforming Patient Pathways: The Impact of Pharmaceutical Software on Drug Manufacturing and Safety Monitoring
Abstract: The development, production, and safety monitoring of pharmaceuticals are being revolutionized by incorporating digital technologies. Throughout drug lifecycles, pharmaceutical software which includes cloud-based systems, automation, data analytics, and artificial intelligence (AI) has emerged behind efficiency and innovation. Real-time monitoring, predictive maintenance, and process optimization are made possible in manufacturing by software tools like Digital Twins, Manufacturing Execution Systems (MES), and Quality Management Systems (QMS). These technologies improve batch consistency, lower …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 40–46 Read article
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Evaluating the Role of Pharmacists in Managing Antibiotic Use and Combating Multi-Drug Resistance in Hospital Settings
Abstract: Antibiotic resistance is now one of the crucial health issues of the world, especially in hospitals where high usage of antimicrobials is increasing the rate at which multi-drug resistant (MDR) organisms appear. Misprescription, extended treatment, and over-use of broad spectrum antibiotics play a large role in the development of resistance resulting in the growth of morbidity, mortality and health care expenditure. This review analyses the essentiality of pharmacists in controlling …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 · pp. 12–19 Read article
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Pharmacodynamics and Drug–Receptor Interactions: Integrating PK/PD Modeling with Modern Drug Development
Abstract: Understanding drug action requires an integrated perspective of pharmacodynamics and pharmacokinetics, which together determine therapeutic efficacy and safety. This review provides a comprehensive overview of the mechanisms underlying drug action, with particular emphasis on drug–receptor interactions and their role in modulating physiological responses. Drugs exert their effects primarily through interactions with specific biological targets, including receptors, enzymes, ion channels, and transporters, resulting in a spectrum of desired and adverse outcomes. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 · pp. 33–47 Read article
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AI-Driven Pharmacogenomics and Precision Medicine: Future of Personalized Therapy
Abstract: Pharmacogenomics and artificial intelligence (AI) are emerging as important drivers of precision medicine, enabling healthcare systems to adopt individualized therapeutic approaches. Pharmacogenomics examines how genetic variations influence drug response, efficacy, metabolism, and toxicity, while AI provides advanced computational tools for analyzing complex genomic and clinical data. This review highlights the integration of AI-driven pharmacogenomics in personalized therapy and its potential to improve treatment outcomes. Machine learning, deep learning, natural language …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 2, 2026 · pp. 1–12 Read article
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THE BURDEN OF EMPIRICAL THERAPY: ANALYZING THE PREDOMINANCE OF BROAD-SPECTRUM ANTIBIOTIC USAGE IN LOWER RESPIRATORY TRACT INFECTIONS
Abstract: Lower respiratory tract infections (LRTIs) remain one of the leading causes of morbidity and hospitalization worldwide, particularly among older adults, immunocompromised individuals, and patients with chronic respiratory disorders. These infections include conditions such as community-acquired pneumonia, hospital-acquired pneumonia, bronchitis, and acute infective exacerbations of chronic lung disease, all of which often require rapid clinical intervention. Because microbiological confirmation of the causative pathogen frequently takes 48–72 hours, clinicians generally initiate empirical …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 Read article
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A Study and Report on Impact of Clinical Pharmacy Services Over Indian Health Care System in the Management of Chronic Disorders/Diseases in Hospital
Abstract: The study aims to ensure safe, effective, economic, and patient friendly with the knowledge inputs of each professional practice. With the primary and secondary objectives being: to study the role of the clinical pharmacist/doctor of pharmacy professional in the management of chronic diseases/illness, minimise medication/prescription errors, minimise/prevent adverse drug reactions, all types of drug interactions, and unnecessary healthcare costs, reducing drug-related problems and to monitor drug therapy efficiently, attain desired …
Published in Research and Reviews: A Journal of Health Professions · Vol. 11, Issue 2, 2021 · pp. 46–82 Read article
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Importance of AYUSH in Present Health Care Perspective
Abstract: The term AYUSH stands for Ayurveda, Yoga & Naturopathy, Unani, Siddha and Homeopathy systems of medicine. Within these medical systems, drug therapies play an important role in curing disease and maintaining health. These drugs comprise of natural molecules which are better absorbed and utilized in the human body and produce effect without adverse drug reaction in comparison to the synthetic molecules. Realizing the 21stcentury is termed as the “Century for …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 4, Issue 3, 2015 · pp. 5–8 Read article
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Comparison between Intravenous Injection of Iron Sucrose and Oral Administration of Iron for the Treatment of Iron Deficiency Anemia in Pregnancy
Abstract: The aim of this study was to compare the therapeutic benefits of intravenous iron and oral iron administration for the treatment of iron deficiency anemia (IDA) in pregnancy. A total of 50 patients with gestational age between 25 and 35 weeks with established IDA with Hemoglobin (Hb) 7–9 g/dl were randomized to receive either oral ferrous sulphate 200 mg twice daily or required dose of intravenous iron sucrose 200 mg …
Published in Research and Reviews : Journal of Surgery · Vol. 5, Issue 3, 2016 · pp. 25–28 Read article
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Artificial Intelligence -Driven in Clinical Pharmacy Practice: Transforming Medication Management and Patient-Centred Care
Abstract: Artificial intelligence (AI) is transforming clinical pharmacy practice by enhancing the safety, accuracy, and efficiency of medication management while supporting evidence-based clinical decision-making. Recent advances in machine learning, deep learning, natural language processing, and predictive analytics have enabled the integration of AI into various aspects of pharmacy practice, including drug discovery, pharmacovigilance, clinical decision support, personalized medicine, medication adherence, and patient counselling. The objective of this review is to provide …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 3, 2026 Read article
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Patterns of Antihypertensive Drug Utilization in a West Indies University Teaching Hospital
Abstract: Objective of this study was to determine the prescribing patterns of antihypertensive medications in specialty outpatient clinics in a tertiary care hospital of a Caribbean developing country. A retrospective prescription-based survey was conducted in the renal and cardiac outpatient clinics during the period September to December 2006. Data recorded included demographic data, antihypertensive and other drugs prescribed, duration of prescription, adverse drug reactions and side effects. A total of 285 …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 5, Issue 1, 2014 · pp. 26–34 Read article
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Pharmacovigilance Programme of India
Abstract: Pharmacovigilance is defined as the pharmacological science relating to the detection, assessment, understanding and prevention of adverse effects, principally long term and short term adverse effects of medicines. It is an important and integral part of clinical research. India is the world’s second most populated country with over one billion potential drug consumers. Although, India is participating in the UMC program, its contribution to the UMC database is very little. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 4, Issue 3, 2014 · pp. 13–23 Read article
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Desferrioxamine-induced Ototoxicity (SNHL) in β-Thalassaemia
Abstract: Thalassaemia is a hereditary disorder requiring regular blood transfusion. The repeated transfusion results in an iron overload state with succeeding complications. Iron chelation therapy with desferrioxamine removes excess iron and its prolonged usage causes ototoxicity. This is a rare disease observed in the ENT (OP) Department, Rajiv Gandhi Institute of Medical Sciences (RIMS) [a 750 bedded tertiary teaching hospital], Kadapa, AP, India. A 12-year-old female patient was presented with complains …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 6, Issue 1, 2016 · pp. 10–12 Read article
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Effect of Polyherbal Compound (Low Cost) in Management of Insulin Dependent Diabetes Mellitus
Abstract: Diabetes mellitus is chronic ailment associated with life threating target organ damage. The present approach of treatment is to maintain glycaemic level within physiological normal level with different means, which may favour angiopathic changes even with normal blood sugar. Ayurveda believes that Medas i.e. lipid metabolism is important pathological change observed in DM that ends up presentation of elevated level of peripheral blood sugar. The quest is to come with …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 3, Issue 2, 2016 · pp. 31–34 Read article
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A Study on Polypharmacy Effects in Geriatrics in a Tertiary Care Teaching Hospital
Abstract: Polypharmacy/polymedicine/multiple drugs is the use of four or more medications by a patient. Geriatrics or geriatric medicine is a specialty that focuses on health care of elderly people. Polypharmacy are the major risk factor of adverse drug reactions (ADRs). Elders are prone to multiple diseases is the leading cause for the using of polypharmacy. It increases hospital staying, cost of medications. Health care providers should evaluate the prescription, simplifying the …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 4, Issue 1, 2017 · pp. 36–38 Read article
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Traditional Medicinal Plants of Odisha
Abstract: This study summarises the traditional medicinal plant of Odisha. Use of plants as a supply of medicine has been an ancient tradition and is a very important part of the health care system in India. General public, academic and government interest in conventional medicines is growing speedily because of the rise in side effects of the adverse drug reactions and issue of the present system of medicine. It is estimated …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 7, Issue 3, 2020 · pp. 7–10 Read article
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The Era of Pharmacology Toward Pharmacogenomics
Abstract: In both Modern Laboratory medicine as well medical science both the Pharmacogenomics is fast, emerging, outcome driven approach which is generally termed as precision medicine. Understanding the importance of gene-drug association and clinical implementation, effect of drug choices over the clinical subjects are kind of need of hour as it is proof of concept for evidence driven therapeutic approach. Also, in research prospective the genome wide association studies (GWAS) which …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 12, Issue 2, 2022 · pp. 33–38 Read article
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Efficacy of Panchakarma in Hypermelanosis from Chloroquine Side Effect: A Case Report
Abstract: Long-term use of chloroquine can sometimes lead to adverse drug reactions manifesting as hypermelanosis, rashes, itching, rashes, eruption etc. Skin hyperpigmentation is generally of a bluish black or grayish color and irreversible even after discontinuation of the drug. This condition can be conceived according to Ayurveda, Dushivisha (DV)—a poisonous substance which is not fully endowed with the qualities of poison by nature and because of its mild potency; it remains …
Published in Trends in Drug Delivery · Vol. 4, Issue 1, 2017 · pp. 4–7 Read article
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A Study and Report on the Role of Clinical Pharmacy Services Provided by the Doctor of Pharmacy in the Management of Thyroid Disorders (Hyperthyroidism and Hypothyroidism) to a Tertiary Care Hospital
Abstract: Thyroid hormones affect the function of virtually every organ system. In children, thyroid hormone is critical for normal growth and development but in adults, the main role of these thyroid hormones is to maintain stability. The main thyroid hormones which play such an important are the Thyroxine (T4) and Triiodothyronine (T3) hormones. Hence, Thyroid disorders encompass a variety of disease states affecting thyroid hormone production or secretion that result in …
Published in Trends in Drug Delivery · Vol. 8, Issue 2, 2023 · pp. 25–38 Read article
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Concise Review on Pharmacological Interventions in Diabetes: Impediment and Treatment
Abstract: Purpose about review: Diabetes is related with metabolic condition which is growing rapidly nowadays. The main reason behind the disease is autoimmune devastation of pancreatic beta cells that lead the impair action of the insulin on the tissues. Recent findings: Synthetic medications have various adverse drug reactions as well as treatment of cost is high. Consequently, herbal medicines have rising interest and gowning to replace the synthetic medications currently. Inference: …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 13, Issue 3, 2022 · pp. 14–20 Read article
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Polypharmacy and the need of deprescribing in Geriatric Chronic Kidney Disease patients
Abstract: Polypharmacy and Hyper polypharmacy pose risk for geriatric population by increasing drug interactions and side effects. This calls for deprescription to remove potentially inappropriate medications (PIM) from their prescription. BEERs criteria (BC) was used to classify medications for PIM. It also includes addition of a new drug, dose reduction and replacement with a newer drug. This study was conducted to find out the need of deprescription in geriatric population suffering …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 9, Issue 1, 2022 · pp. 1–4 Read article