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80 articles for “ADR”
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Influence of Antibiotic Promotion Practices on Pharmacovigilance and Resistance Reporting Patterns
Abstract: The global escalation of antimicrobial resistance (AMR) has emerged as a critical public health crisis, undermining decades of therapeutic advancements. While inappropriate prescribing and misuse of antibiotics are widely acknowledged contributors, the role of pharmaceutical promotion practices remains underexplored in influencing prescribing behaviors and downstream pharmacovigilance systems. This review critically examines how antibiotic promotion strategies – ranging from direct physician engagement to digital marketing – affect adverse drug reaction (ADR) …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 · pp. 1–11 Read article
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An Appraisal of Medhya Rasayana (Nootropic Herbs) In Present Scenario
Abstract: Rasayana tantra is a branch of ayurveda which describes the measures of attaining long life, maintenance of youthfulness, increasing immunity and providing excellent nutrition to all the body tissues. Rasayana on regular practice boosts nourishment, health, memory, immunity and longevity. Rasayana can be classified as Dravyabhuta and Adravyabhuta Rasayana. Adravyabhuta Rasayana includes Aachara Rasayana and Dravyabhuta Rasayana; classified as Kamya Rasayana, Naimittika Rasayana and Ajasrika Rasayana. Medhya Rasayana (nootropic herbs) …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 7, Issue 1, 2018 · pp. 27–32 Read article
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Case Report on Nevirapine Induced Exfoliative Dermatitis
Abstract: Nevirapine is the first drug of non-nucleoside reverse transcriptase inhibitors (NNRTI) class to treat seropositive patients, administered along with protease inhibitors and/or NRTIs. Nevirapine binds directly to reverse transcriptase (RT) and blocks the RNA-dependent and DNA-dependent polymerase enzyme. Exfoliative dermatitis is wide spread erythema and scaling of skin caused by pre-existing skin disorders, drugs and cancer, unknown causes. HIV infected patients are more prone to Exfoliative Dermatitis. This is a …
Published in Research and Reviews: A Journal of Medicine · Vol. 5, Issue 2, 2015 · pp. 7–10 Read article
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Medical Management of Benign Prostatic Hyperplasia
Abstract: Benign prostatic hyperplasia is one of the most prevalent diseases in elderly men. Medical therapies are targeted to relieve obstruction by relaxing smooth muscles(α-blocker) or promoting regression of the disease process (androgen ablation).Three major classes of drugs have been used for the medical management of BPH are α-adrenergic receptor antagonist, hormones and phytotherapy. Selective α 1 receptor antagonist is effective in the treatment of BPH. The development of specific α …
Published in Research and Reviews : Journal of Surgery · Vol. 3, Issue 1, 2014 · pp. 23–25 Read article
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Patterns of Antihypertensive Drug Utilization in a West Indies University Teaching Hospital
Abstract: Objective of this study was to determine the prescribing patterns of antihypertensive medications in specialty outpatient clinics in a tertiary care hospital of a Caribbean developing country. A retrospective prescription-based survey was conducted in the renal and cardiac outpatient clinics during the period September to December 2006. Data recorded included demographic data, antihypertensive and other drugs prescribed, duration of prescription, adverse drug reactions and side effects. A total of 285 …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 5, Issue 1, 2014 · pp. 26–34 Read article
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Pharmacovigilance Programme of India
Abstract: Pharmacovigilance is defined as the pharmacological science relating to the detection, assessment, understanding and prevention of adverse effects, principally long term and short term adverse effects of medicines. It is an important and integral part of clinical research. India is the world’s second most populated country with over one billion potential drug consumers. Although, India is participating in the UMC program, its contribution to the UMC database is very little. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 4, Issue 3, 2014 · pp. 13–23 Read article
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Glibenclamide Induced Linear Immunoglobulin: A Dermatosis (LAD)
Abstract: Linear immunoglobulin A dermatitis is a rare autoimmune sub epidermal blistering disorder characterised by continuous deposition of IgA in the basement membrane zone. The disease may be drug related (glibenclamide) or non-drug related (Haematological, rheumatological). This is a rare disease observed in dermatology (IP) department, RIMS, Kadapa. A 50 years old female patient presented lesions on the trunk and purpuric eruptions since 2 months along with oral ulceration and itching. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 6, Issue 1, 2016 · pp. 1–3 Read article
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Desferrioxamine-induced Ototoxicity (SNHL) in β-Thalassaemia
Abstract: Thalassaemia is a hereditary disorder requiring regular blood transfusion. The repeated transfusion results in an iron overload state with succeeding complications. Iron chelation therapy with desferrioxamine removes excess iron and its prolonged usage causes ototoxicity. This is a rare disease observed in the ENT (OP) Department, Rajiv Gandhi Institute of Medical Sciences (RIMS) [a 750 bedded tertiary teaching hospital], Kadapa, AP, India. A 12-year-old female patient was presented with complains …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 6, Issue 1, 2016 · pp. 10–12 Read article
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“High Melatonin Milk”- Milk with Intrinsic Health Benefit
Abstract: Melatonin C13H16N2O2 (molecular weight: 232) or N-acetyl-5-methoxytryptamine, is chemically an indoleamine and derived from the essential amino acid tryptophan. It is a hormone and due to secretion from pineal gland, it is also called as active pineal factor. Its IUPAC name is N-[2-(5-methoxy-1H-indol-3-yl)ethyl] acetamide. The indole ring acts as the chromophore showing maximum absorbance at 223 nm, and the functional groups contribute to its fluorescence property. Lerner et al. 1959 …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 5, Issue 1, 2016 · pp. 13–16 Read article
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Adverse Drug Reactions Monitoring by Healthcare Professionals in Noida, Uttar Pradesh Region—A Study on Knowledge, Attitude and Method of Application
Abstract: The study was aimed to assessing the knowledge, attitude and method of application towards adverse drug reactions reporting by the doctors and other healthcare professionals (HCPs) in Delhi-NCR (Noida region), to get an insight into the causes of under-reporting of adverse drug reactions (ADRs) and to suggest possible ways of improving this method of reporting. A structured validated questionnaire was used consisting of 10 questions divided into three components; awareness, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 7, Issue 3, 2017 · pp. 1–6 Read article
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A Study on Polypharmacy Effects in Geriatrics in a Tertiary Care Teaching Hospital
Abstract: Polypharmacy/polymedicine/multiple drugs is the use of four or more medications by a patient. Geriatrics or geriatric medicine is a specialty that focuses on health care of elderly people. Polypharmacy are the major risk factor of adverse drug reactions (ADRs). Elders are prone to multiple diseases is the leading cause for the using of polypharmacy. It increases hospital staying, cost of medications. Health care providers should evaluate the prescription, simplifying the …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 4, Issue 1, 2017 · pp. 36–38 Read article
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An Insight to Diagnosis and Management of Druginduced Hepatotoxicity: An Overview
Abstract: (ADRs) Adverse Drug Reactions are constitute and mutual chief health problem. Throughout the last period liver toxicity has remained one of the most recurrent reasons for pharmacovigilance protection intelligences and the withdrawal from the marketplace of an accepted medicinal product. Liver is a main organ elaborate in the systemic deposition and decontamination of exogenous and endogenous ingredients. Liver disfunction challenges not only health care specialists but also the pharmaceutical manufacturing …
Published in Trends in Drug Delivery · Vol. 8, Issue 2, 2023 · pp. 39–54 Read article
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Designing Engaging Interactive Animatronics: Strategies and Implementation Insights
Abstract: The field of animatronics uses robotic systems to imitate realistic movements and activities in mechanical figures. To enhance the recognition and performance of the animatronic as a relationship mediator, it is important that the animatronics in recreational games be perceived as human companions to create productive interaction scenarios. This study describes the design and implementation of a Java- based programming method, an Adriano microcontroller, an open environment, a depth camera …
Published in International Journal of Optical Innovations & Research · Vol. 1, Issue 2, 2023 · pp. 27–33 Read article
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Global Burden of Major Depressive Disorder: Prevalence, Diagnosis, and Impact: A Comprehensive review
Abstract: In this review, we will discuss about the major depressive disorders on the basis of neurobiological changes. MDD, a prevalent psychiatric condition, manifests as a complex interplay of genetic, environmental, and physiological factors with a substantial impact on individuals and societies globally. Here the clinical assessment is fully based on diagnosis and the statistical manual for mental disorder, 5th edition (DSM-5). The pathophysiology involves Diagnosis alterations in neurotransmitter systems, dysregulation …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 54–62 Read article
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Biokinetics of Retention and Dose Delivery to Body Organs due to Protracted Ingestion of Natural Uranium in Groundwater of Patiala District, Punjab, India
Abstract: This study pertains to the uranium concentration in the drinking water and its biokinetics of the retention and dose delivered to body organs of the residents of 50 villages of the Patiala district of the Punjab State where U content is higher than the safe limit of 30 ppb fixed by WHO. U content values vary from 38.0 µg/L (Uppli) to 267.0 µg/L (Ahru Kalan) with an average value of …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 3, 2024 · pp. 1–15 Read article
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Unravelling the Environment, Aroma, and Molecular Effects on Mood Fluctuations: A Review
Abstract: The ebb and flow of human emotions encompass a complex interplay of molecular processes governing mood fluctuations. This comprehensive review navigates the intricate realm of neurotransmitters, neuroplasticity, hormonal influences, genetics, and inflammation to unravel the molecular tapestry that shapes our emotional states. Foundational to mood regulation are neurotransmitters – serotonin, dopamine, and norepinephrine – orchestrating delicate balances within neural circuits. Recent molecular neuroscience elucidates their receptor pathways and signaling cascades, …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 3, 2024 · pp. 14–20 Read article
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Role of Ginger (Zingiber officinale Roscoe) in Sustainable Health
Abstract: Attaining sustainable health involves a comprehensive blend of multiple factors, including structural, physiological, metabolic, and psychological aspects, alongside the cultivation of self-awareness and a sense of fulfillment. The World Health Organization (WHO) underscores in its 2030 Agenda for Sustainable Development that lifestyle-related illnesses, especially non-communicable diseases (NCDs), present considerable hurdles to sustainable progress, stressing the importance of mitigating their risk factors. Nutrition is acknowledged as a cornerstone of health preservation, …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 72–76 Read article
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Artificial Intelligence in Pharmacovigilance: Improving Drug Safety
Abstract: Artificial intelligence (AI) is revolutionizing pharmacovigilance (PV) by enhancing the detection, assessment, and prevention of adverse drug reactions (ADRs). This review examines how AI technologies – such as machine learning (ML), natural language processing (NLP), and big data analytics – tackle existing challenges in pharmacovigilance (PV), including issues like underreporting, large data volumes, and inefficiencies in data processing. AI improves drug safety by automating data collection, enabling real-time adverse event …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 1, 2025 · pp. 1–16 Read article
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Mind-Gut Connection: The Psychosomatic Effects of Stress and Emotions on Digestive System
Abstract: Stress, understood as an immediate disruption to bodily equilibrium, triggers an adaptive or allostatic response that impacts gastrointestinal function both in the short and long term. The enteric nervous system communicates in both directions with the brain through parasympathetic and sympathetic pathways, collectively forming what is known as the brain-gut axis. Unani scholars describe stress as a response to the loss of something valuable, such as an opportunity, a desired …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 1, 2025 · pp. 11–14 Read article
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Pharmacology in Clinical and Therapeutic Settings
Abstract: Polypharmacy, which refers to the practice of taking many medications at the same time, is becoming more common among elderly populations as a result of the steadily increasing prevalence of chronic conditions. The clinical and therapeutic consequences of polypharmacy are investigated in this paper, with a particular emphasis placed on drug-drug interactions, altered pharmacokinetics, and patient safety. The physiological changes that occur with advancing age have a substantial impact on …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 51–58 Read article