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837 articles for “Clinical”
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Fenugreek: A Traditional Herb with Modern Health Applications
Abstract: Fenugreek (Trigonella foenum-graecum) is a remarkable herb with a rich history that stretches back over 4, 000 years. It has played an important role in traditional medicine systems like Ayurveda, Unani, and Traditional Chinese Medicine. Cultivated widely in places like India, the Mediterranean, and North Africa, fenugreek’s seeds and leaves have been used to treat a variety of ailments, from digestive and respiratory issues to skin problems and inflammation. Recent …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 1, 2024 · pp. 11–21 Read article
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Utilize Nature’s Power: Nutraceuticals in the Fight Against Dengue
Abstract: As dengue fever continues to surge across tropical and subtropical regions, the exploration of novel therapeutic approaches is crucial. Nutraceuticals, natural bioactive compounds derived from food sources, are emerging as promising adjuncts in the fight against this viral disease. Unlike conventional treatments that primarily target symptoms, nutraceuticals offer a complementary strategy by enhancing the body’s immune defense and addressing key complications. This review highlights the diverse potential of nature’s remedies, …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 1, 2025 · pp. 19–27 Read article
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Screening Phytocompounds of Tinospora cordifolia to Find Potential Drug Targets for Cystic Fibrosis
Abstract: This study aimed to evaluate the therapeutic potential of phytocompounds derived from Tinospora cordifolia in treating cystic fibrosis (CF), a genetic disorder caused by mutations in the CFTR gene that lead to severe respiratory and digestive complications. Phytocompounds were retrieved from the IMPPAT database and subjected to molecular docking simulations using PyRx to assess their binding affinity to the CFTR protein. The top-scoring compounds – sterol, magnoflorine, tembetarine, kaempferol, and …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 16–24 Read article
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Management of Varicose Veins: A Review of Literature
Abstract: Lower extremities venous insufficiency is a frequent disorder that can cause a variety of symptoms, such as ulceration, soreness, swelling, and bulging leg veins. Whereas there is many other treatment choices, the more recent endovascular treatments are simple, safe, rapid, and very effective at reducing symptoms. Foam sclerotherapy, thermal ablation, and mechanical chemical ablation are minimally invasive endovascular techniques commonly used in the treatment of varicose veins. This review article …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 1, 2025 · pp. 17–21 Read article
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A Review: Homeopathic Remedies and Their Potential Neurological Implications in Depression and Asthma
Abstract: Homeopathy, based on the principle “like cures like”, has gained popularity as a complementary treatment for chronic diseases, including depression and asthma. Both health conditions have a profound impact on the quality of life of individuals and are often treated with pharmacological interventions such as antidepressants and bronchodilators. This review reviews homeopathic remedies used to treat depression and asthma, evaluating the available clinical evidence. Although some studies suggest that homeopathy …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 1, 2025 · pp. 15–20 Read article
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Nanocarrier-mediated CRISPR/Cas9 Gene Editing of BMP2 for Bone Repair
Abstract: The growth factor that plays an important role in the formation and repair of bones is bone morphogenetic protein 2(BMP2). Nevertheless, because BMP2 is rapidly degrading and has less than half the time to live, its delivery into bone defects may be difficult. A plan to develop a nanocarrier via CRISPRCas9 gene editing mechanism for the delivery of BMP2 into bone defects is outlined in this research proposal. The system …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 1, 2025 · pp. 14–21 Read article
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Ethical Consideration in the Use of Artificial Intelligence in Medicine and Healthcare
Abstract: Artificial Intelligence (AI) in medicine and healthcare offers tremendous potential for improving patient care, increasing the precision of diagnoses, and increasing operational efficiency. To ensure responsible application, however, the swift uptake of AI technologies also brings up important ethical concerns that need to be addressed. This article explores various ethical challenges in healthcare AI, including concerns about algorithmic bias, data privacy, informed consent, and accountability. Patients must be aware of …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 1, 2025 · pp. 23–28 Read article
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A Compressive Review of Traditional Medicine System of Naturopathy (Nature): Evaluation, Standardization of Alternative Medicine
Abstract: Naturopathy is a therapeutic approach that combines scientific principles with the natural laws of the body. It focuses on using natural methods to promote healing and overall well-being. This traditional practice combines various techniques, such as herbal medicine, nutritional guidance, hydrotherapy, and physical therapy, to treat the underlying causes of illnesses rather than just managing symptoms. The growing interest in alternative medicine necessitates a comprehensive evaluation and standardization of naturopathic …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 1, 2025 · pp. 22–29 Read article
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Biomedical Coatings: Surface Engineering for Enhanced Biocompatibility and Performance
Abstract: Biomedical coatings have become essential in modern healthcare, significantly improving the performance, durability, and biocompatibility of medical implants and devices. These coatings serve multiple functions, including reducing infection risks, enhancing osseointegration, promoting tissue integration, and enabling localized drug delivery. Advances in surface engineering have led to the development of innovative coatings with superior properties such as antimicrobial resistance, bioactivity, and controlled biodegradation. Various materials are employed in biomedical coatings, including …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 1, 2025 · pp. 8–15 Read article
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Transfer Learning in Deep Learning Models for Medical Imaging: Utilizing Pretrained Models to Improve Performance in Medical Image Analysis
Abstract: Transfer learning is now a trending technique in deep learning, especially in medical imaging. This technique solves landmark problems by utilizing the pre-trained models, including the limited availability of the annotated medical data and the time-consuming computational costs of training deep learning models from scratch. The generalizability of deep models could increase diagnostic precision for specific medical tasks, require fewer samples to train, and take less time to train due …
Published in Journal of Image Processing & Pattern Recognition Progress · Vol. 12, Issue 1, 2025 · pp. 67–85 Read article
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Exploring the Effects of Yogic Meditation on Stress, Anxiety, and Cardiovascular Health: A Prospective Cross-Sectional Cohort Study at Desh Bhagat Hospital
Abstract: Background: Stress and anxiety are significant risk factors for cardiovascular disorders, with growing evidence suggesting that yogic meditation can mitigate these effects. This prospective cross-sectional cohort study was conducted to evaluate the impact of yogic meditation on stress, anxiety, and cardiovascular parameters among patients attending Desh Bhagat Hospital. Methods: A cohort of 350 patients was recruited, comprising individuals presenting with elevated stress, anxiety, or cardiovascular conditions. Participants underwent a guided …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 1, 2025 Read article
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Visualization of genomic sequence in BRCA1 and BRCA2
Abstract: Heredity is the main reason of breast cancer in women and mutation or genetic variations also another reason for the spread of breast cancer. Heredity and genetic variations are responsible 5%-10%, 30%-50% respectively. There are 90% chances of developing neoplasm by the mutations. The effect of BRCA1 and BRCA2 may leads to the variations in DNA therefore it should be in limited amounts so that there will be minimum changes …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 49–55 Read article
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A Study on Ekakushtha (Psoriasis) With Its Ayurvedic Management
Abstract: The skin, the delicate outer layer of vertebrates, often reflects internal imbalances and stress-related conditions within the body. In Ayurveda, the skin (Tvak) is considered a mirror of internal health, revealing various abnormalities or disorders. All skin diseases are collectively categorized under the term "Kushtha" in Ayurvedic texts. The ancient Acharyas explain that Kushtha involves the imbalance of all three doshas, with the specific type of Kushtha determined by the …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 1, 2025 Read article
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Computational Investigation of Phytochemicals Targeting AKT1 for Major Depressive Disorder: A Molecular Docking and ADMET Study
Abstract: Major depressive disorder (MDD) is a prevalent neuropsychiatric condition affecting approximately 280 million individuals worldwide, with women exhibiting a 50% higher likelihood of diagnosis than men. Despite significant advancements in treatment, MDD remains a chronic and relapsing disorder, necessitating the exploration of novel therapeutic interventions. This study focuses on the AKT1 gene, a key player in neuropsychiatric disorders, and investigates its interactions with natural phytochemicals as potential alternatives to conventional …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 2, 2025 Read article
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The Effect of Vitamin A Dose For Different Periods On The Spleen of White Rats: A Histological Study
Abstract: There are many detrimental effects of hypervitaminosis (A) on immune system function, growth, and reproduction. The main objective of the study was to evaluate the histological changes in the spleen of white rats given an excessive amount of vitamin A. The study was conducted from October 21, 2022, to December 12, 2022, at the College of Education's Animal House. (40) adult male albino rats, weighting between 200 and 220 grams …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 15, Issue 2, 2025 Read article
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Radiopharmaceuticals use as a nuclear medicine for a Treatment of Disease
Abstract: Radiopharmaceuticals are radioactive substances that contain a bonded radionuclide with the intention of directing the radionuclide to a specific place for treatment or imaging. Radiopharmaceuticals are employed in nuclear medicine for cancer therapy as well as other therapeutic and diagnostic applications. Therefore, the primary goal of this study is to identify the key metal complexes and radioactive elements utilized in radiopharmaceutical applications. The sodium and methylenediphosphonate (MDP-99mTc) complexes, along with …
Published in Journal of Nuclear Engineering & Technology · Vol. 15, Issue 1, 2025 · pp. 17–21 Read article
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Therapeutic Potential of Plant-Derived Phytochemicals in Targeting Receptor Pathways Related to Non-Enzymatic Glycation: A Meta-Analysis
Abstract: Background: Non-enzymatic glycation, where reducing sugars react with proteins, lipids, and nucleic acids, contributes to various pathological conditions, such as diabetic complications and cardiovascular diseases. This process is facilitated by the receptor for advanced glycation end-products (RAGE), which is pivotal in driving inflammation and causing tissue damage. Objective: This meta-analysis evaluates the effects of plant-derived phytochemicals on RAGE expression and associated signaling pathways, assessing their therapeutic potential in glycation-related diseases. …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 60–73 Read article
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Tobacco and COVID-19: Molecular Interactions and Public Health Challenges – A Review
Abstract: Tobacco use exacerbates health risks, making it a significant concern during the COVID-19 pandemic. Smoking has been implicated in the upregulation of ACE2 receptors, critical for SARS- CoV-2 entry, and contributes to immune dysregulation and oxidative stress, worsening clinical outcomes. Methods: This review synthesizes evidence on the molecular mechanisms linking tobacco and COVID-19, assesses risk factors, such as smoking status and comorbidities, and explores public health challenges in managing the …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 1–6 Read article
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Screening of Pharmaceutically Significant Methioninase-Producing Fungi from the Satpura Range of Hoshangabad District and Its Large-Scale Production
Abstract: L-methioninase, an enzyme with notable anticancer properties, has emerged as a promising therapeutic agent due to its ability to selectively degrade methionine, a critical amino acid for the survival of methionine-dependent cancer cells. Methionine dependency, observed in many tumor cells, is a metabolic vulnerability that can be exploited for targeted cancer therapy. The Satpura Range in the Narmadapuram District, India, with its diverse microbial ecosystems, offers a rich reservoir for …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 2, 2025 · pp. 33–43 Read article
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COSMECEUTICAL: The Intersection Between Beauty and Science
Abstract: The intersection of beauty and science has given rise to the rapidly growing field of cosmeceuticals—products that blend cosmetic and pharmaceutical elements to improve both the appearance and health of the skin. As consumers increasingly seek advanced, evidence-based skincare solutions, the demand for cosmeceuticals has surged. These products typically contain bioactive ingredients that go beyond simple aesthetic enhancement, offering therapeutic benefits backed by scientific research. The article explores the evolving …
Published in Recent Trends in Cosmetics · Vol. 2, Issue 1, 2025 · pp. 17–31 Read article