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1972 articles for “4-dioxopyrimidine-5-carbonitrile” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Construction and Development of pSB111 Bar Plasmid Vector for Activation Tagging
Abstract: To get desired traits and to know the precise expression patterns of genes in the plant, Agrobacterium tumefaciens has been widely employed in the generation of transgenic plants using plasmid vectors. Many methods are come forward to establish the gene expression of unknown genes but in these techniques gene alteration isthe main drawback orsometimesit islethal to organisms also, to overcome these problems activator tag method developed to know the specific …
Published in Research & Reviews : Journal of Botany Read article
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Molecular Characterization of Circulating Rota Viral Strain causing infantile diarrhoea in Tripura, North East India
Abstract: Introduction: North Eastern India is geographically distinct from rest of India and the trend of Rota viral diarrhoea among children below 5 years of age group is not well studied yet. The Government of India introduced the oral rotavirus vaccine (ROTAVAC) in 2016 as part of the Universal Immunization Programme in different parts of India. Objective: (1). To determine the proportion of circulating Rotavirus strains causing acute viral gastroenteritis (AGE) …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 11, Issue 3, 2021 · pp. 6–13 Read article
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Pharmacoinformatic Based Screening Of Phytocompound Epigallocatechin Gallate To Identify As A Potential Bcl-2 Inhibitor
Abstract: Objectives: The B-cell lymphoma-2 (Bcl-2) is a protein that is particularly though to be involved in preventing apoptosis. Bcl-2 family members also essential for cancer survival, and its over expression has been linked to tumor genesis, development and resistance to anticancer treatments. The Bcl-2 family of members that inhibit apoptosis is a promising target for the creation of anticancer drugs. Methods: The study was based on computational approach using different …
Published in International Journal of Bioinformatics and Computational Biology Read article
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An Integrated Study to Extrapolate the Interaction of NMDAR with Potential Ligands for the Treatment of Alzheimer’s Disease Symptoms
Abstract: Objective: Alzheimer’s disease (AD) is the most common neurodegenerative disease affecting the health status of older adults especially those above the age of 60 years. As an outcome, two types of medications have been developed for the treatment of its symptoms which are acetylcholinesterase (AChE) and N-methyl-D-aspartate receptor (NMDAR) antagonist. This paper uses the computational approach to understand the interaction of NMDAR with four major phytocompounds (curcumin, L-epicatechin, ginsenosides, and …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 15–27 Read article
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Factors Affecting Uptake of COVID-19 Vaccines Among Adults: A Cross Sectional Survey
Abstract: The COVID-19 vaccination started in phased manner in India, and it was first time when a digital platform was developed for vaccine site registration. People had skepticism about newly developed vaccines and had poor understanding of using digital platform for vaccination registration. It was one of the reasons for poor vaccination coverage in marginalized section of the society. The pandemic has also affected other healthcare services as people were worried …
Published in International Journal of Community Health Nursing And Practices · Vol. 1, Issue 2, 2023 Read article
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Effect of Formaldehyde Treatment on the Barrier and Mechanical Properties of Oat Protein Films
Abstract: Oat protein 5% with 40% glycerol as a plasticizer was used to prepare edible films, and formaldehyde was chemically added to the film's solution at four concentrations. The films' barrier and mechanical properties were then investigated. The films were characterized by being medium transparency, homogeneous, odorless, and with a thickness ranging between 0.12 and 0.15 mm. It was also observed that the water vapor permeability decreased whenever the concentration of …
Published in Journal of Polymer & Composites · Vol. 11, Issue 2, 2023 · pp. 1–8 Read article
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Production of Disinfectant Using Aloe Vera (Aloe barbadensis miller) Plant Extracts
Abstract: This research work demonstrates the production of a disinfectant using aloe vera (Aloe barbadensis Miller) as main source of the raw material. The liquid content of the aloe vera was extracted using mechanical and unit operation mechanisms and the obtained raw material was subjected to heating to evaluate the effect of temperature on the characteristics of the physiochemical properties of pH, total ash, crude fat, fibre and protein, total carbohydrate, …
Published in International Journal of Pollution: Prevention & Control · Vol. 1, Issue 1, 2023 · pp. 17–30 Read article
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Properties of Concrete with Reinforcement Eggshell Powder As Cement
Abstract: Many people choose concrete because of its reputation for durability and dependability. Concrete is not only strong and consistent, but also energy efficient, design flexible, cheap, and generally ecofriendly. In addition to protecting natural ecosystems, stable civilizations often make plans for further industrialization and urbanization. As long as it is utilized in a compositionally flexible and ecologically friendly way, concrete may be used to create aesthetically stunning structures. Inadequate domestic …
Published in Journal of Polymer & Composites · Vol. 11, Issue 4, 2023 · pp. 46–52 Read article
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A Comparative Study of Zinc Oxide Nano Particles Synthesized by Hydrothermal, Sol-gel and Thermal Decomposition
Abstract: In the proposed work, Zinc oxide nano particles (ZnO NP's) are synthesized using three different methods: Hydrothermal, Sol-gel and Thermal decomposition. The samples are characterized using X- ray diffraction (XRD), UV visible spectroscopy (UV-Vis), Fourier Transform Infrared Spectroscopy (FT-IR) and scanning electron microscopy (SEM). The XRD pattern exhibit single-phase polycrystalline nature of all the samples exhibiting the most intense peak at (101). The diffraction peaks are located at 31.80, 34.46, …
Published in Journal of Polymer & Composites · Vol. 11, Issue 7, 2023 · pp. 39–45 Read article
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Experimental Investigation of Aerodynamic Characteristics of Dimpled 3D Aircraft Wing
Abstract: There is a strong demand for innovative designs, optimization of the aircraft components for their parts with respect to design, etc. One such innovation is by introduction of dimples in the wing of the aircraft. To study the effect of geometry modification of the wing, the present work compares the aerodynamic efficiency, ratio of lift to drag coefficients, along with different aerodynamic characteristics of an Inward and outward circular dimpled …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 1, Issue 1, 2023 · pp. 11–22 Read article
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Evaluating the Impact of a Structured Teaching Program on the Knowledge of Mothers with Children Under Five Regarding Upper Respiratory Tract Infections and Home Remedies in a Selected Primary Healthcare Area in Bengaluru
Abstract: Background: Upper Respiratory Tract Infections are contagious infections involving the nose, throat sinuses, pharynx, larynx, tonsils, and adenoids. The typical upper respiratory tract infections are nasopharyngitis (common cold), tonsillitis, sinusitis, laryngitis, and pharyngitis etc., Precautionary measures in early stages can help to prevent complications. Further, home remedies can offer comfort from symptoms and reduce the duration of illness and these home remedies have no side effects, but also boost up …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 14–19 Read article
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A Study to Assess the Effectiveness of Awareness Programme on Knowledge Regarding Health Problems Related to Smart Phone Addiction Among Adolescents Studying in a Selected School, Bangalore, Karnataka
Abstract: Aim: This study assesses the effectiveness of an awareness program on adolescents' knowledge of health problems related to smartphone addiction. Objectives: (1) Evaluate adolescents' understanding of health issues linked to smartphone addiction. (2) Measure the impact of the awareness program on their knowledge by comparing pre-test and post-test scores. (3) Investigate correlations between pre-test knowledge and sociodemographic variables. Method: A quantitative evaluative approach was used. The one-group pre-test post-test research …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 9–13 Read article
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DESIGN AND ANALYSIS OF A METAL LINED COMPOSITE OVERWRAPPED PRESSURE VESSEL
Abstract: This study presents a comprehensive investigation into the mechanical behavior of a metal lined composite overwrapped pressure vessel, designed for high-pressure storage applications. The design approach is dependent upon fiber material constants and dome shape factor. The study begins with obtaining dome coordinates and maintaining winding angles according to a geodesic path equation. Thickness estimation for the portion of cylindrical shell and domes are determined through netting analysis and cubic …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 215–232 Read article
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A Concurrent Estimation of Phytoconstituents Piperine, Quercetin and Kaempferol Present in Siddha Polyherbal Formulation Kabasara Kudineer by Rp-Hplc
Abstract: A straightforward, accurate, and precise technique was developed and validated for the simultaneous determination of Quercetin, Kaempferol, and Piperine in the polyherbal formulation Kabasura Kudineer. The sample was chromatographed using a C18 column (150x4.6mm, 5u) with a mobile phase composed of Acetonitrile and Ortho phosphoric acid in a 45:55 ratio, flowing through the column at a rate of 1ml/min. The detection wavelength for Quercetin, Kaempferol, and Piperine was set at …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 1–9 Read article
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Study The Effect of Metakaolin Powder in Hot Mix Asphalt as Mineral Filler
Abstract: Mineral fillers are crucial for bridging the spaces between the internal particles of the asphalt matrix. The purpose of this study is to investigate the mechanical properties of hot mix asphalt as well as the impact of utilising Metakaolin (MK) as a mineral filler. Coarse aggregate, fine aggregate, and filler are the main components of hot mix asphalt (HM). With or without modifiers, materials and asphalt binders. HMA components have …
Published in Journal of Polymer & Composites · Vol. 11, Issue 10, 2023 · pp. 9–15 Read article
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Influence of Aspect Ratio on the Mechanical and Tribological Properties of Vertical Centrifugal Cast Aluminium Silicon Alloy
Abstract: To get a sound cast of precise shape and size in the vertical centrifugal casting process, the flow behavior of the melt and process parameters such as aspect ratio of the mould, rotating speed, volume fraction, etc. must be optimized. The optimal parameters of the vertical centrifugal casting process derived from past cold modelling studies in casting of Al-12%Si alloy are investigated in this paper. Casts were obtained using 7 …
Published in Journal of Polymer & Composites · Vol. 11, Issue 13, 2023 · pp. 104–111 Read article
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Evaluation Of Anti Obesity Activity Of Citrus Sinensis & Citrus Limon By High Fat Diet Induced Model Using Danio Rerio
Abstract: Obesity, defined by the World Health Organization (WHO) as an abnormal or excessive fat accumulation that may impair health, is becoming one of the greatest challenges to global health in this millennium, with more than 300 million men and nearly 450 million women obese globally in 2018. Obesity turns into serious problem globally. Zebrafish model can be used extensively for drug screening due to its low maintenance cost, comparatively short …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 1, 2024 · pp. 24–31 Read article
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Strategic Enhancement of Composite Strength Explored Through Comprehensive Integration of Flax Fiber and Cenosphere in Epoxy Resin Matrices
Abstract: The Current research delves into the mechanical attributes of composite specimens, integrating flax fiber and cenosphere fillers within an epoxy resin matrix catalyzed by K-6 hardener. Executing a meticulous approach involving a vacuum bagging method and a specific formulation of 10 wt.% cenosphere, 50% epoxy resin, and 40% flax fibers, the study rigorously scrutinized tensile and flexural strengths. Notably, the first specimen exhibited a peak tensile strength of 94.329 MPa, …
Published in Journal of Polymer & Composites · Vol. 11, Issue 13, 2023 · pp. 199–217 Read article
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Optimization of Seed Viability Tests for Humulus lupulus
Abstract: The Humulus lupulus member of the Hemp family has been extensively explored for their industrial application in diverse sectors. During the cultivation of this high-cost plant, one of the major concerns associated is low seed germination due to physical dormancy. The role of rigid seed coats in augmenting an impermeable barrier for water and nutrient availability to the seed has been well analyzed in previous studies. However, the associated impact …
Published in Research & Reviews : Journal of Botany · Vol. 13, Issue 1, 2024 · pp. 1–6 Read article
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Evaluation Of the Quality of Sleep in Healthy Individuals Based on Practice of (CYP)- A Pilot Study.
Abstract: Introduction-Sleep is basic requirement of all living beings. Specially, in human beings it is considered as one of the supportive factor of existence. Ahara(food), Nidra(sleep) and Bramhacharya(righteous conduct/celibacy) are the three factors explained in classical texts as Traya Upastambha(Tripods). Not only Ayurveda literatures, its description and importance is available in Upanishads too. Mandukya Upanishad has allotted a full chapter on sleep and consciousness. But, as the era has entered into …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 1, 2024 · pp. 40–47 Read article