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552 articles for “HIV-1 Integrase” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Significance of Composite Materials for Making Better Future Society
Abstract: Since in the beginning of human history, Materials had been started in use. We can't imagine our world without materials. In fact, Materials has taken centre position in many developed and developing countries. The materials that humans have chosen to use for engineering projects throughout history, including the Stone, Iron, and Silicon ages. However, in order to meet today's difficulties, new materials must be discovered and developed with the necessary …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 2, 2023 · pp. 56–62 Read article
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Contemporary Ethno-Religious Development Crises in Northern Nigeria with a Special Reference to Some States: Genesis, Implication, Impact and the Quest for Prospect
Abstract: A study has been conducted purely for the exploration of the remote and immediate factors that frequently lead to the outbreak of the studied subject matter in the region and period under review. In this study, a multitude number of published and unpublished sources have been put into use for appropriate historical reconstruction of some major obstacles associated with political, economic, social, tribal and religious aspects of the region and …
Published in International Journal of Trends in Humanities · Vol. 2, Issue 1, 2025 · pp. 32–40 Read article
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Development of A Gyratory Bladed Grinding Machine for Ripe Plantain Processing
Abstract: The processing of ripe plantains faces significant challenges, including inefficient grinding and mortar pasting methods, inconsistent paste quality, and maintenance difficulties with existing equipment. This paper presents the development of a gyratory bladed grinding machine specifically for ripe plantain processing. SOLIDWORKS CAD software was applied to create the machine's CAD, or computer-aided design, model. The design analysis of the machine components was conducted, and appropriate materials were selected to accommodate …
Published in International Journal of Industrial and Product Design Engineering · Vol. 2, Issue 2, 2024 · pp. 29–37 Read article
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Mobility for the Exceptionals: An Adaptable Electrified Transportation System for Manual Wheelchair
Abstract: The survey for the prevalence of handicapped people in India reveals that approximately 4.52% of India’s total population is physically challenged. Among the list, about 44% of people suffer from locomotor disability. Satisfaction of their primary need will be fulfilled when they get aid to move but the main problem is that about 31% of India’s population belongs to middle class or lower middle class. Their wish to buy an …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 2, Issue 2, 2024 · pp. 21–25 Read article
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From Mourning to Manipulation: Navigating the Psychological Terrain of AI Grief Therapy
Abstract: This literature review explores the psychological and ethical dimensions of virtual conversations with AI-based digital representations of deceased individuals. Specifically, it examines the therapeutic affordances of these interactions, as well as potential maladaptive coping mechanisms, including prolonged mourning, emotional exploitation, and memory distortion. Based on a review of 13 academic studies from 2021 to 2024, this paper critically analyzes ethical dilemmas related to informed consent, data commodification, and the autonomy …
Published in International Journal of Behavioral Sciences · Vol. 2, Issue 1, 2025 · pp. 34–41 Read article
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The Association Between Intergenerational Trauma, Perceived Social Support and Post Traumatic Growth among Young Adults
Abstract: This study explores the intricate relationship between intergenerational trauma, perceived social support, and post-traumatic growth (PTG) among young adults in the Indian subcontinent. Drawing on a sample of 199 participants, the research examines how adverse childhood experiences (ACE) transmitted across generations impact individuals' psychological well-being and their capacity for growth. In particular, the study looks into how perceived social support from friends, family, and other people can help to moderate …
Published in International Journal of Children · Vol. 2, Issue 1, 2025 · pp. 1–8 Read article
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Evaluation of the influence of supportive education on the religious beliefs and practices of cervical cancer patients in managing the disease at Tertiary Health Institutions in Ebonyi State, Nigeria
Abstract: This study investigated how 60 cervical cancer patients in a tertiary care facility in Ebonyi State, Nigeria How to use Cervical Cancer Support Education (CCSE) to manage their care. Using a quasi-experimental design, 60 participants were divided into an intervention group from two health institutions and a control group from the National Obstetric Fistula Centre. The research used a quasi-experimental design and collected data over a 13-month period using a …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 96–111 Read article
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Effect of the Integrated Approach to Yoga Therapy on Stress-Related Anxiety Disorder of a Roller Skater
Abstract: Anxiety and stress are common problems for competitive skaters, which frequently impairs their performance and general health. The Integrated Approach to Yoga Therapy (IAYT) offers a holistic intervention, addressing the physical, mental, and emotional dimensions of health. This study investigates the impact of IAYT on stress-related anxiety disorders in skaters, incorporating yoga postures (asanas), breathing techniques (pranayama), meditation, and relaxation practices. An 8-week intervention was conducted with 30 competitive skaters …
Published in Recent Trends in Sports · Vol. 2, Issue 1, 2025 · pp. 7–13 Read article
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A Sensitive SPE-ECD-GLC Procedure for Analyzing Simazine Quantitatively in Food Products
Abstract: Short and simple solid-phase extraction (SPE) method interfacing and hyphenating gas liquid chromatographic-electron capture detection (GLC-ECD) method has been developed for the qualification and quantification of simazine in some daily used agro products. United States Pharmacopeia G-42 gas chromatography stationary phase with ZB-35a, HTb Inferno-cZ (Zebron, Za) capillary column with an enlarged and extended temperature range of –60° to 400°C and electron capture detector was selected correlating some chemical, physical …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 20–27 Read article
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QSAR Modeling of a Novel Series of Methoxylated Chalcones as Antioxidant Agents Against Gram-Positive Bacteria Staphylococcus aureus
Abstract: Background: Chalcones are aromatic ketones belonging to the flavonoid family. They are plant-based compounds and are widely found in nature. For centuries, these bioactive molecules have been utilized in various traditional medicines for the treatment of several ailments. Chalcones have antibacterial, antiviral, antimalarial, antifungal, antioxidant, and antileishmanial properties. They are also used to treat inflammation and cancer. Chalcones act as angiogenesis inhibitors, an important factor in cancer progression and metastasis. …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 28–34 Read article
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The Pursuit of Passion: Navigating Career Choices in Today’s Competitive Landscape
Abstract: In today’s world, it’s common to see people chasing after name, fame, and wealth. While there’s nothing inherently wrong with ambition, this persistent pursuit often comes at the expense of genuine happiness, fun, and enjoyment. This is particularly evident among teenagers, who face immense pressure from their parents, peers, and societal expectations. Parents often place their unfulfilled dreams and aspirations onto their children, hoping they will achieve swift success and …
Published in International Journal of Children · Vol. 2, Issue 1, 2025 · pp. 32–36 Read article
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Smart Protective System for EVs
Abstract: Electric vehicles, or EVs, form the bedrock of sustainable transportation, offering both energy efficiency and low carbon emissions. However, the safety issues emanating from the complexity of road conditions call for innovative solutions. This paper introduces a Smart Protective System for EVs, integrating YOLOv5 for real-time obstacle and pothole detection with ultrasonic sensors for proximity measurement. The system is able to achieve an object detection accuracy of 95% under normal …
Published in International Journal of Advanced Control and System Engineering · Vol. 3, Issue 1, 2025 · pp. 8–14 Read article
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Eco-Friendly Synthesis of MgO Nanoparticles and Their Antibacterial Performance
Abstract: Nanoparticles (<100 nm in size) due to their enhanced surface area and high chemical reactivity have been a boon, ranging from micro to macro level. This has increased its applicability in various fields such as Food, textile, environment, biomedicine etc. Various metal oxides have been employed in Biomedical applications for their antibacterial, antioxidant and anticancerous activities. But MgO NPs have received much attention due to their high stability, non-toxicity and …
Published in International Journal of Advance in Molecular Engineering · Vol. 3, Issue 1, 2025 · pp. 33–41 Read article
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A Review of Embodied Energy Strategies to reduce the carbon emissions in Sustainable Buildings
Abstract: Buildings in India account for almost one-fifth of the nation's carbon emissions, making it the third- largest carbon emitter globally. These emissions are expected to climb by 50% over the next 20 years, which is the biggest increase of any nation. You would have to go into a jungle to avoid concrete, steel, and aluminium since they are so common. Just these three substances are responsible for 23% of the …
Published in International Journal of Architectural Design and Planning · Vol. 3, Issue 1, 2025 · pp. 18–27 Read article
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Quinine: Past, Present, and Future Perspective in Malaria and Autoimmune Disorder
Abstract: Quinine, a natural alkaloid extracted from the bark of the cinchona tree, has traditionally played a key role in treating malaria, a disease caused by parasites of the Plasmodium genus. Since its discovery in the 17th century, quinine has evolved from a rudimentary treatment to an essential component of modern antimalarial therapies. This article explores the historical use of quinine in the fight against malaria, its role in current treatment …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 24–33 Read article
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Cyber Security Challenges in Developing Countries: A Special Reference to Afghanistan
Abstract: This review paper explores the widespread cybersecurity challenges encountered by developing countries, specifically concentrating on Afghanistan during the period from 2020 to 2024. The study highlights the significant gaps in cybersecurity capabilities, infrastructure, and regulatory frameworks that exacerbate the vulnerability of these nations to cyber threats. Key findings include the lack of basic legal frameworks for countering cybercrime, with only a minority of African states, and presumably other developing regions …
Published in International Journal of Information Security Engineering · Vol. 3, Issue 1, 2025 · pp. 1–6 Read article
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From Rural to Urban: Understanding Taobao Villages to Redress Planetary Urbanisation
Abstract: This study examines Taobao Villages as an innovative model of urbanisation under China’s planetary urbanisation framework. These rural communities, driven by the rise of e-commerce and digital infrastructure, have successfully integrated into the broader urban ecosystem by reconfiguring their historical socio-spatial legacies. Through Lefebvre’s spatial triad framework, the research identifies three key historical legacies that underpin this transformation: (1) Collective Production Practices: Rooted in socialist collectivisation, these legacies include organisational …
Published in International Journal of Urban Design and Development · Vol. 3, Issue 1, 2025 · pp. 1–7 Read article
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On The Risk of Urban Road Pavement Failure: A Case Study of Owerri, Imo State
Abstract: In this research work, we study the risk of road pavement failures in Owerri Imo State. The study deviates from other research work in this area that focused on the nature of road pavement failures without considering the risk involved with respect to human life and others. This was the aspect the study delved into. The researchers used questionnaires to collect primary data from randomly selected respondents on axle load …
Published in International Journal of Urban Design and Development · Vol. 3, Issue 1, 2025 · pp. 16–24 Read article
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A Machine learning approach to asses carbon emission, utility to produce biomaterial
Abstract: The transportation sector, and the automotive industry in particular, has grown significantly over the last ten years. However, these quick advancements have also brought about important problems that require workable answers. The problem of carbon emission is responsible for global warming due to greenhouse gas emission. The present work is focused on CO2 emission from public and personal transport within Agra city on a real-time basis. In the context of …
Published in International Journal of Advanced Control and System Engineering · Vol. 3, Issue 1, 2025 · pp. 22–30 Read article
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An Efficient Synthesis of Some Novel Benzo Coumarin Derivatives Under Solvent Conditions from 2-acetyl-benzo[f]chromen-3-one
Abstract: The synthesis of the target compounds began with the preparation of 2-[3-dimethylamino[acryloyl-3H-benzo[f]chromen-3-one. This intermediate was obtained through the reaction of 2-acetylbenzo[f]coumarin-3-one with N,N-dimethylformamide dimethyl acetal [DMFDMA[ under reflux conditions in xylene. The enaminone thus formed was subsequently reacted with 6-aminothiouracil in acetic acid, leading to the formation of 2-thioxo-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one. This compound served as a pivotal intermediate for the synthesis of a series of pyridotriazolopyrimidinones. These derivatives were synthesized by reacting …
Published in International Journal of Cheminformatics · Vol. 2, Issue 2, 2024 · pp. 33–46 Read article