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1721 articles for “association”
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Molecular Docking and Interaction of Anthocyanin Derivatives in Regulating Hippo-taz Pathway for Renal Injuries
Abstract: Introduction: The Hippo pathway plays a pivotal role in renal disease, with Yes-associated protein (YAP) exhibiting promise for combined treatments. The crucial evaluation of YAP-targeted drug safety and efficacy through preclinical studies is imperative. Additionally, α-SMA and SMAD3 emerge as potential therapeutic targets in renal fibrosis, driving ongoing research toward innovative interventions. Materials and Methods: In the systematic identification of therapeutic secondary metabolites, Anthocyanin derivatives were methodically retrieved from the …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 23–38 Read article
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Data Integrity Best Practices in Pharmaceutical Quality Assurance: A Thorough Review
Abstract: Data integrity stands as a linchpin in the reliability and trustworthiness of systems involved in handling, analyzing, and retrieving information, safeguarding the accuracy and consistency of data from inception to disposal. This paper delves into the multifaceted realm of data integrity, encompassing its definition, pivotal importance, regulatory underpinnings, core principles, and practical implementation strategies. A comprehensive exploration of regulatory guidelines, including ICH Q7, EU Annexure 11, and FDA regulations, underscores …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 1, 2024 · pp. 22–30 Read article
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Stretching Boundaries: A Comprehensive Review of Ehlers-Danlos Syndrome and its Subtypes
Abstract: The Ehlers-Danlos syndromes (EDS) encompass 13 inheritable disorders affecting connective tissue. These conditions arise from genetic alterations impacting the structure of connective tissue. Every variant of Ehlers-Danlos syndrome (EDS) exhibits distinct features and has specific diagnostic criteria. While certain traits such as joint hypermobility, skin hyperextensibility, and tissue fragility are common across all types of EDS. The range of clinical presentations spans from minor skin and joint looseness to severe …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 44–57 Read article
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Exploring the Potential of Recyclable Steel in Circular Economies
Abstract: As the global community faces the pressing challenges of environmental degradation and resource depletion, the imperative for sustainable solutions has never been more pronounced. This research introduces an in-depth exploration into the realm of recyclable materials, with a specific emphasis on steel—an essential component in various industries and a major contributor to environmental impact. The research investigates current recycling technologies and processes that facilitate the transformation of steel into a …
Published in International Journal of Manufacturing and Production Engineering · Vol. 1, Issue 2, 2023 · pp. 25–40 Read article
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Analysing Dietary Patterns and Unravelling the Factors behind Obesity: A Comprehensive Evaluation
Abstract: The purpose of this research paper is to identify the changes that occurred in the food habits of people in the past few years. This research is based on the findings for the evaluation that have been done on the food habits of people in the past few years and the rise of the rate of obesity percentage and the rate of diabetic patients in these years. And finding the …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 1, 2024 · pp. 45–50 Read article
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Harnessing the Healing Potential of Khamira Abresham Hakim Arshad Wala in the Management of Different Health Conditions
Abstract: Khamira Abresham Hakim Arshad Wala (KAHAW) is a potent Unani remedy that plays a vital role in fortifying the body's vital organs and efficiently reducing free radicals by enhancing levels of antioxidant enzymes. The term 'Khamira' originated from the Unani system of medicine and was first introduced by the esteemed Hakeem during the Mughal period. This preparation involves incorporating herbal drugs into a base (Qiwam) containing sugar or honey, resulting …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 11, Issue 1, 2024 · pp. 7–13 Read article
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Rise of Nationalism in Globalized Society
Abstract: This comprehensive study explores the intricate phenomenon of the resurgence of nationalism on a global scale, examining its multifaceted dimensions, underlying drivers, and potential implications for contemporary societies. In the complex landscape of the 21st century, the resurgence of nationalism has become a prominent and dynamic force, influencing political, social, and economic structures worldwide. The research methodology employed in this study integrates both qualitative and quantitative analyses, drawing on historical …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 14, Issue 1, 2024 · pp. 59–68 Read article
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Comparative Study to Assess the Attitude of Higher Secondary School Students Regarding Career Counselling in Selected Rural and Urban Schools of Kashmir
Abstract: Background: Career counselling is a process that involves working with a professional to explore and understand various aspects of one's personality, skills, interests, values, and goals to make informed decisions about your career. Aim: The main aim of the study was to assess the attitude of higher secondary school students regarding career counselling in selected rural and urban schools of Kashmir. Methods: This study employed a descriptive research design using …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 11–18 Read article
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Unani Medicine Uncovered: Core Concepts And Quality Evaluations
Abstract: Unani medicine, a traditional healing system primarily reliant on herbal remedies, finds its roots in the ancient wisdom of Greek philosopher Hippocrates (460–377 BC) and his associates. Its evolution and prominence, however, owe much to the support of Persian and Arab empires before making its way to the Indian subcontinent around the mid-14th century. Unani practitioners believe that each individual possesses a unique temperament shaped by the interplay of four …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2024 · pp. 10–17 Read article
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Optimizing Manufacturing Processes with Taguchi Method in Production Engineering
Abstract: The Taguchi Method, pioneered by Genichi Taguchi, stands as a powerful optimization tool within the realm of production engineering. This paper delves into the principles, applications, and significance of the Taguchi Method in enhancing manufacturing processes. With a focus on minimizing variation and improving performance, this methodology plays a crucial role in addressing challenges faced by industries in their pursuit of operational excellence. The core components of the Taguchi Method, …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 1, Issue 2, 2023 · pp. 1–8 Read article
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Data Compression for Backbone Network
Abstract: This article involves the application of data compression techniques to improve the efficiency and performance of the core infrastructure of modern digital networks. This approach focuses on reducing the size of transmitted data without compromising its quality, aiming to enhance network throughput, reduce latency, and minimize energy consumption. The study also considers practical implementation challenges and trade-offs to optimize resource utilization in backbone networks. We delve into various compression methods, …
Published in Journal of Multimedia Technology & Recent Advancements · Vol. 11, Issue 1, 2024 · pp. 30–40 Read article
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Designing and Developing a Cancer Chatbot in a Website
Abstract: Cancer is a disease that affects millions of people worldwide each year and is characterized by the rapid growth of cells that are abnormal. The outcome is affected since numerous cases are discovered at advanced stages of the disease. Anxiety and depression are two mental health issues that frequently coexist with the illness, worsening its effects on sufferers. There were many medical apps that provide guidelines for patients, but these …
Published in Journal of Multimedia Technology & Recent Advancements · Vol. 11, Issue 1, 2024 · pp. 1–9 Read article
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Enhancing Road Safety with the Latest Breakthrough: Real-time Vehicle Classification, Counting, and Speed Estimation Using YOLOv8n and Deep SORT Algorithm
Abstract: The real-time vehicle classification, counting, and speed estimation system based on YOLOv8n is an important tool for monitoring traffic flow on highways. However, because they are distinct objects from their surroundings, it is still difficult to detect them, which has an impact on how accurate vehicle counts are. To tackle this concern, this paper suggests the implementation of a vision-centric system for real-time vehicle monitoring and identification. The approach involves …
Published in Research & Reviews: A Journal of Embedded System & Applications · Vol. 12, Issue 1, 2024 · pp. 10–18 Read article
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Classifying Abnormalities in Heartbeat Sound
Abstract: Heartbeat sounds play a major role in the detection of various diseases such as heart disease, hyperthyroidism, and high blood pressure in their early stages. In the proposed method, various abnormal and healthy heartbeat audio signals are given as input and the features are extracted using MFCC (mel-frequency cepstral coefficients). Then, a deep learning approach is applied in which the MFCC audio signals are sent to the CNN (convolutional neural …
Published in Research & Reviews: A Journal of Embedded System & Applications · Vol. 12, Issue 1, 2024 · pp. 24–31 Read article
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The Eco-Friendly Future of Publishing and Literature Distribution Particularly in India
Abstract: This research paper explores the potential of eco-friendly methods in publishing and literature distribution, focusing on their usefulness and future impact, particularly in India. This paper aims to explore the potential impact and usefulness of eco-friendly methods in publishing and literature distribution, shedding light on the latest technologies and methods that can contribute to a greener future. In recent years, there has been a growing concern about the environmental impact …
Published in OmniScience: A Multi-disciplinary Journal Read article
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Federated Learning for Energy Management in Next Generation Smart Cities
Abstract: Federated learning has emerged as a promising approach for addressing the challenges of energy management in next-generation smart cities. This decentralized approach to machine learning allows collaborative model training among distributed data sources, while safeguarding data privacy and security. In this study, we explore the application of federated learning techniques to optimize energy consumption, enhance grid stability, and promote sustainability in smart city environments. By aggregating data from diverse sources …
Published in Journal of Communication Engineering & Systems · Vol. 14, Issue 1, 2024 · pp. 19–27 Read article
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Developing a Chatbot System Utilizing Artificial Intelligence and Natural Language Processing
Abstract: Software applications commonly feature a user interface that falls into broad categories, namely graphical user interface (GUI), text-based UI, or a blend of both. This interface is predominantly employed in web-based and desktop applications. A chatbot, designed to engage with users, operates through the storage and retrieval of session data. It proves particularly beneficial in situations where obtaining information about individuals who are not affiliated as students or employees of …
Published in Journal of Software Engineering Tools & Technology Trends · Vol. 11, Issue 1, 2024 · pp. 24–29 Read article
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Integrated risk assessment framework for mixed use real estate development: Retail–office configuration
Abstract: Mixed-use real estate development is a multifaceted challenge that offers significant potential benefits, yet developers and urban planners face skepticism and uncertainty. Despite the promise of enhancing property values, promoting secure neighborhoods, stimulating economic vitality, and creating synergies, the associated risks demand a critical examination. This research seeks to address this gap by constructing a comprehensive risk assessment framework for mixed-use real estate projects. The literature review underscores the substantial …
Published in International Journal of Rural and Regional Development · Vol. 2, Issue 1, 2024 · pp. 22–36 Read article
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DRIVE-DEFENDER: A Driver Safety-oriented Alcohol and Drowsiness Detection System
Abstract: DRIVE-DEFENDER presents a pioneering approach in driver safety through the development of a real-time machine learning system for alcohol detection. The detrimental impact of alcohol-impaired driving on road safety necessitates efficient detection mechanisms. Current methodologies are often hindered by their cost, invasiveness, and reliance on specialized sensors. DRIVE-DEFENDER utilizes a camera for recording the face of the driver in real time, employing image processing techniques to identify facial landmarks. These …
Published in Journal of Open Source Developments · Vol. 11, Issue 1, 2024 · pp. 15–26 Read article
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Impact of Red Stone Dust and Polymer Fabric in Enhancing the Properties of Black Cotton Soil
Abstract: To enhance the mechanical properties of problematic black cotton soil, engineers are focusing on reinforcing the soil with geosynthetic materials. This attention is particularly directed towards improving the strength characteristics of black cotton soil, given its inherent challenges associated with volume changes and plasticity. In this comprehensive study, red stone dust waste is introduced in varying percentages ranging from 5% to 35% to stabilize the black cotton soil. The goal …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 35–43 Read article