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1962 articles for “IDS” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Exploring Phytochemicals from Ricinus Communis for Potential Therapeutic Applications in Rheumatoid Arthritis: An in-Silico Approach
Abstract: Aim: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by the immune system mistakenly attacking the joints, leading to swelling, discomfort, and joint deformities. Current management strategies include anti-rheumatic drugs and biologics, which have limitations. This study aims to explore the therapeutic potential of Ricinus communis (castor bean plant) phytochemicals as plant-based therapies for autoimmune conditions, like RA. Methods: Phytochemicals from Ricinus communis were retrieved using the IMPPAT database, …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 32–41 Read article
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Self-Navigating Rover for Real Time Mapping and Disaster Management
Abstract: This paper presents the development of an autonomous rover designed for mapping and object detection in challenging terrains. The rover integrates a 6-wheel rocker-bogie mechanism for enhanced mobility and stability, making it suitable for rugged and uneven environments. Key components include an Arduino Uno for control operations, a Camera module for real-time visual data capture and object detection, and a LiDAR for precise distance measurement and spatial mapping. The system …
Published in Journal of Aerospace Engineering & Technology · Vol. 15, Issue 1, 2025 · pp. 23–33 Read article
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Enhancing Engine Efficiency and Reducing Emissions: A Comprehensive Review of Air Calorimeter Technology
Abstract: The article talks about the idea behind this project to pre-heat the intake air that passes through the carburettor to increase a petrol engine's fuel efficiency. The vaporization of petrol in the carburettor is influenced by the humidity of the surrounding air. Therefore, vaporization can be facilitated, and full combustion can be accomplished by preheating the carburettor's incoming air for a significant amount of time. Additionally, by lowering the amount …
Published in Journal of Aerospace Engineering & Technology · Vol. 15, Issue 1, 2025 · pp. 8–13 Read article
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Repurposing Approved Immunomodulatory Drugs for Target Proteins in the Pancreas of European eel: A Molecular Docking Approach
Abstract: Leishmaniasis is a disease caused by tiny parasites called Leishmania, which spread to humans through the bite of an infected female sand fly. The disease manifests in three different forms, and the protein calcitonin promotes the disease’s spread. By reducing blood calcium levels, inhibiting osteoclast activity, increasing calcium excretion, and possibly playing a role in neurotransmitter modulation, calcitonin, a hormone released by vertebrates, promotes the progression of pathogenesis and lessens …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 12–19 Read article
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Design and Performance Analysis of Sustainable Hybrid Composites for Impact Absorption and Lightweight Applications.
Abstract: This study explores the mechanical and structural properties of a novel hybrid composite composed of recycled tyre rubber, ceramics, and wood. The investigation focuses on key parameters, including energy absorption, compressive and tensile strength, and density, to evaluate the composite's suitability for diverse applications. The impact energy absorption test revealed that Sample A, comprising 50% rubber, 25% ceramic, and 25% wood, exhibited the highest energy absorption capability, with an average …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 95–104 Read article
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Modeling and Simulation of Feed Forward Temperature Controller with Effect of Higher Gain on Chemical Reactors Heat Exchangers
Abstract: Chemical reactors are widely used in pharmaceutical process industries. The temperature controller design is an essential part of heat exchangers (HE) design for such reactors. The goal of this research is to design and validate the Feed Forward (FF) temperature compensator for the stared tank chemical rectors. The aim is to analyze the impact of high turbulence (Gain) performance on step response. For temperature management, a transfer function (TF) control …
Published in Journal of Thermal Engineering and Applications · Vol. 12, Issue 1, 2025 · pp. 30–40 Read article
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Precision Medicine Approaches for Cancer Therapy Recent and Advance
Abstract: Recent advances in biotechnology have made it possible to identify intricate and distinctive biological characteristics linked to carcinogenesis. Proteomic and RNA studies, immunological markers, tumor and cell-free DNA profiling, and other methods are utilized to find these traits in order to optimize anticancer treatment for specific patients. In recent years, the focus of clinical trials has shifted considerably to enhance treatment outcomes in cancer therapy. Rather than being primarily centered …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 1, 2025 · pp. 1–11 Read article
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Image Processing and Deep CNN-based Automatic Liver Cancer Detection
Abstract: Liver cancer ranks among the leading causes of mortality for people worldwide. In the current situation, manually identifying the cancer tissue is a challenging and timeconsuming task. Treatment planning, response monitoring, tumor load assessment, and prediction are all made possible by the segmentation of liver lesions in CT scans. To address the current problem of liver cancer, the Hybridized Fully Convolutional Neural Network (HFCNN), which has been theoretically modeled, has …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 1, 2025 · pp. 39–41 Read article
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Understanding Leukemogenesis: Challenges and Advancements in Diagnostic Approaches
Abstract: Leukaemia development, or leukemogenesis, is a multifactorial process driven by a complex interplay of environmental, genetic, and epigenetic factors. Despite substantial advancements in technology and medicine, which have enhanced our understanding of the contributing factors, early and accurate diagnosis remains a major challenge due to the overlapping clinical features shared by the various leukaemia subtypes. This study explores the molecular and cellular mechanisms underlying leukemogenesis, while also addressing the difficulties …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 1, 2025 · pp. 11–22 Read article
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Real-Time Object Detection and Tracking in Traffic Surveillance: Implementing Algorithms That Can Process Video Streams for Immediate Traffic Monitoring
Abstract: The rapid growth in urban development and traffic congestion calls for adopting high standards of traffic surveillance systems for monitoring. This paper reviews the current advancement and future trends of real-time object detection and tracking technology and its implications for traffic surveillance. Conventional approaches to traffic monitoring can provide more or less accurate data, but they are not easily scalable and cannot cope with rapidly changing conditions typical within urban …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 3, Issue 1, 2025 · pp. 18–39 Read article
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Design and Implementation of an Automatic Fire Extinguishing System Using Arduino UNO
Abstract: Fire safety is an essential concern in both residential and industrial spaces. Conventional firefighting techniques frequently call for human assistance, which is not always adequate or timely. This study discusses the design and development of an automatic fire suppression system that uses an Arduino UNO microcontroller, a 5 V single-line relay, an infrared (IR) sensor, a buzzer, and a 5 V DC pump. The system identifies a fire by detecting …
Published in Journal of Microelectronics and Solid State Devices · Vol. 12, Issue 1, 2025 · pp. 6–12 Read article
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Computational Analysis of Tinospora Cordifolia Phytochemicals as Potential Inhibitors of BRCA1-BRCT Domain Interaction in Breast Cancer
Abstract: Breast cancer is a leading cause of cancer-related deaths worldwide, accounting for a significant proportion of mortality rates among women. Despite current therapeutic approaches, the disease remains characterized by molecular heterogeneity, making it challenging to develop effective treatments. This study explores the potential of Tinospora cordifolia, a medicinal plant, in breast cancer therapy. Guduchi, scientifically known as Tinospora cordifolia, boasts a centuries-long history of use in traditional medicine, with a …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 27–37 Read article
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Computational Investigation of Phytochemicals Targeting AKT1 for Major Depressive Disorder: A Molecular Docking and ADMET Study
Abstract: Major depressive disorder (MDD) is a prevalent neuropsychiatric condition affecting approximately 280 million individuals worldwide, with women exhibiting a 50% higher likelihood of diagnosis than men. Despite significant advancements in treatment, MDD remains a chronic and relapsing disorder, necessitating the exploration of novel therapeutic interventions. This study focuses on the AKT1 gene, a key player in neuropsychiatric disorders, and investigates its interactions with natural phytochemicals as potential alternatives to conventional …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 2, 2025 Read article
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Diversity and Sustainability: The Role of Traditional Fruit Trees in Uttarakhand Agricultural Landscape
Abstract: Uttarakhand state is characterized by a rich diversity of traditional fruit trees. Uttarakhand is largely a mountainous state, with only around 10% of its overall geographical area being plains, and more than three-quarters (78%) of its total people relying on agriculture for survival. The state's geographical features and climatic circumstances are suited for growing temperate and subtropical fruit crops. It provides a variety of agro-geoclimatic conditions that are ideal for …
Published in International Journal of Land · Vol. 1, Issue 2, 2024 · pp. 22–25 Read article
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A GIS and MCDA Framework for Land Suitability Analysis in Sustainable Agriculture
Abstract: This study examines land suitability for sustainable agriculture by integrating Geographic Information Systems (GIS) and Multi-Criteria Decision Analysis (MCDA) as tools to optimize agricultural planning. Sustainable agricultural practices are increasingly critical to meet global food demands without depleting essential land resources. This research focuses on assessing specific parameters that determine the agricultural viability of land, including soil characteristics, topography, climatic conditions, and water availability. These criteria are integral to understanding …
Published in International Journal of Land · Vol. 1, Issue 2, 2024 · pp. 30–34 Read article
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Unmasking Human Metapneumovirus: The Emerging Threat to Vulnerable Populations
Abstract: Human Metapneumovirus (HMPV) is a contagious respiratory virus that commonly spreads among individuals. It can cause serious infections, especially in high-risk groups like infants, older adults, and individuals with weakened immune systems.It is a major contributor to acute respiratory illnesses. Since its discovery in 2001, HMPV has been identified as a common cause of both upper and lower respiratory tract illnesses, with clinical presentations ranging from mild symptoms to severe …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 16–24 Read article
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Screening of Newer Phytoconstituents on Novel Enzymes for their Biological Activity
Abstract: Background: Hyperlipidemia and gout are prevalent metabolic disorders significantly impacting global health. The xanthine oxidase and HMG-CoA reductase pathways play pivotal roles in the pathophysiology of these conditions. This study explores the potential of natural phytoconstituents—daidzein, resveratrol, and genistein—as dual inhibitors for these enzymatic targets, offering insights into innovative therapeutic strategies. Aim: To evaluate the potential of natural phytoconstituents—daidzein, resveratrol, and genistein—as dual inhibitors of xanthine oxidase and HMG-CoA reductase …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 81–86 Read article
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Screening of Pharmaceutically Significant Methioninase-Producing Fungi from the Satpura Range of Hoshangabad District and Its Large-Scale Production
Abstract: L-methioninase, an enzyme with notable anticancer properties, has emerged as a promising therapeutic agent due to its ability to selectively degrade methionine, a critical amino acid for the survival of methionine-dependent cancer cells. Methionine dependency, observed in many tumor cells, is a metabolic vulnerability that can be exploited for targeted cancer therapy. The Satpura Range in the Narmadapuram District, India, with its diverse microbial ecosystems, offers a rich reservoir for …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 2, 2025 · pp. 33–43 Read article
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Hormonal Shifts and Vision Changes: Addressing the Needs of Women During and After Pregnancy
Abstract: Pregnancy and the postpartum period are marked by significant hormonal fluctuations that can profoundly affect a woman’s vision health. This review explores the relationship between hormonal shifts during pregnancy and the onset of common vision changes, including but not limited to dry eyes, blurred vision, and retinal changes. These changes are often temporary but can indicate underlying complications such as gestational diabetes, preeclampsia, and other pregnancy-related conditions that may threaten …
Published in International Journal of Women's Health Nursing And Practices · Vol. 3, Issue 1, 2025 · pp. 19–24 Read article
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A Review of Drug Design Techniques Assisted by Computers to Combat Diabetes
Abstract: Diabetes mellitus is a global health concern characterized by chronic hyperglycemia and associated complications. The creation of innovative medicines with enhanced efficacy and safety profiles continues to be a top focus, notwithstanding improvements in treatment. A useful method in drug development, computer-aided drug design (CADD) makes it easier to identify possible therapeutic candidates and optimise lead molecules. An extensive synopsis of CADD tactics used in the fight against diabetes is …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 1–10 Read article